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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MAFF_MAFG

Z-value: 1.21

Motif logo

Transcription factors associated with MAFF_MAFG

Gene Symbol Gene ID Gene Info
ENSG00000185022.7 MAF bZIP transcription factor F
ENSG00000197063.6 MAF bZIP transcription factor G

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFFhg19_v2_chr22_+_38597889_38598021-0.532.8e-01Click!
MAFGhg19_v2_chr17_-_79885576_79885624-0.433.9e-01Click!

Activity profile of MAFF_MAFG motif

Sorted Z-values of MAFF_MAFG motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_3189861 1.22 ENST00000457435.1
ENST00000420429.2
chromosome X open reading frame 28
chr13_-_44453826 0.89 ENST00000444614.3
coiled-coil domain containing 122
chr11_-_914774 0.83 ENST00000528154.1
ENST00000525840.1
chitinase domain containing 1
chr1_+_85527987 0.80 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WD repeat domain 63
chr16_+_66442411 0.72 ENST00000499966.1
long intergenic non-protein coding RNA 920
chr4_-_2243839 0.71 ENST00000511885.2
ENST00000506763.1
ENST00000514395.1
ENST00000502440.1
ENST00000243706.4
ENST00000443786.2
polymerase (DNA directed) nu
HAUS augmin-like complex, subunit 3
chr13_+_44453688 0.70 ENST00000425906.1
laccase (multicopper oxidoreductase) domain containing 1
chr4_-_185655278 0.69 ENST00000281453.5
centromere protein U
chr11_-_94965667 0.69 ENST00000542176.1
ENST00000278499.2
sestrin 3
chr7_+_107220660 0.67 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
B-cell receptor-associated protein 29
chr3_-_150264272 0.66 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
stress-associated endoplasmic reticulum protein 1
chr1_-_68962744 0.61 ENST00000525124.1
DEP domain containing 1
chr8_+_26240414 0.59 ENST00000380629.2
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr6_+_53794780 0.57 ENST00000505762.1
ENST00000511369.1
ENST00000431554.2
muscular LMNA-interacting protein
RP11-411K7.1
chr3_+_172034218 0.56 ENST00000366261.2
Uncharacterized protein
chr7_-_86849883 0.54 ENST00000433078.1
transmembrane protein 243, mitochondrial
chr16_-_56701933 0.54 ENST00000568675.1
ENST00000569500.1
ENST00000444837.2
ENST00000379811.3
metallothionein 1G
chr15_+_23810853 0.53 ENST00000568252.1
makorin ring finger protein 3
chr1_+_89829610 0.52 ENST00000370456.4
ENST00000535065.1
guanylate binding protein family, member 6
chr4_+_26585538 0.52 ENST00000264866.4
TBC1 domain family, member 19
chrX_-_55187588 0.52 ENST00000472571.2
ENST00000332132.4
ENST00000425133.2
ENST00000358460.4
family with sequence similarity 104, member B
chr11_+_114271367 0.52 ENST00000544582.1
ENST00000545678.1
RNA binding motif protein 7
chr12_-_10282742 0.51 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
C-type lectin domain family 7, member A
chr6_-_113953705 0.48 ENST00000452675.1
RP11-367G18.1
chr7_-_92219698 0.48 ENST00000438306.1
ENST00000445716.1
family with sequence similarity 133, member B
chr1_+_110210644 0.47 ENST00000369831.2
ENST00000442650.1
ENST00000369827.3
ENST00000460717.3
ENST00000241337.4
ENST00000467579.3
ENST00000414179.2
ENST00000369829.2
glutathione S-transferase mu 2 (muscle)
chr16_-_66907139 0.47 ENST00000561579.2
NEDD8 activating enzyme E1 subunit 1
chrX_-_20134990 0.46 ENST00000379651.3
ENST00000443379.3
ENST00000379643.5
MAP7 domain containing 2
chr17_+_68047418 0.44 ENST00000586373.1
ENST00000588782.1
long intergenic non-protein coding RNA 1028
chrX_-_107019181 0.44 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22 domain family, member 3
chr12_+_57522692 0.44 ENST00000554174.1
low density lipoprotein receptor-related protein 1
chr12_+_51318513 0.43 ENST00000332160.4
methyltransferase like 7A
chr8_+_125486939 0.42 ENST00000303545.3
ring finger protein 139
chr6_+_159291090 0.42 ENST00000367073.4
ENST00000608817.1
chromosome 6 open reading frame 99
chr5_+_130506475 0.41 ENST00000379380.4
LYR motif containing 7
chr19_-_57967854 0.41 ENST00000321039.3
vomeronasal 1 receptor 1
chr1_-_150669500 0.40 ENST00000271732.3
golgi phosphoprotein 3-like
chr11_+_114271251 0.39 ENST00000375490.5
RNA binding motif protein 7
chr17_-_39216344 0.39 ENST00000391418.2
keratin associated protein 2-3
chr15_+_49913201 0.38 ENST00000329873.5
ENST00000558653.1
ENST00000559164.1
ENST00000560632.1
ENST00000559405.1
ENST00000251250.6
DTW domain containing 1
chr12_+_57522439 0.37 ENST00000338962.4
low density lipoprotein receptor-related protein 1
chr4_-_170924888 0.36 ENST00000502832.1
ENST00000393704.3
microfibrillar-associated protein 3-like
chr19_+_5914213 0.36 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
calcyphosine
chr5_-_42811986 0.36 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr4_+_15683369 0.36 ENST00000503617.1
family with sequence similarity 200, member B
chr5_-_42812143 0.36 ENST00000514985.1
selenoprotein P, plasma, 1
chr6_+_27215494 0.35 ENST00000230582.3
protease, serine, 16 (thymus)
chr15_+_49913175 0.35 ENST00000403028.3
DTW domain containing 1
chr5_-_82373260 0.35 ENST00000502346.1
transmembrane protein 167A
chr7_+_89975979 0.35 ENST00000257659.8
ENST00000222511.6
ENST00000417207.1
GTP-binding protein 10 (putative)
chr7_-_17980091 0.34 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
sorting nexin 13
chr10_-_4720333 0.34 ENST00000430998.2
long intergenic non-protein coding RNA 704
chr14_+_32798547 0.33 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr10_+_43916052 0.33 ENST00000442526.2
RP11-517P14.2
chr11_+_114270752 0.33 ENST00000540163.1
RNA binding motif protein 7
chr15_-_31521567 0.33 ENST00000560812.1
ENST00000559853.1
ENST00000558109.1
RP11-16E12.2
chr11_+_62652649 0.32 ENST00000539507.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr20_+_12989596 0.32 ENST00000434210.1
ENST00000399002.2
serine palmitoyltransferase, long chain base subunit 3
chr2_+_171640291 0.31 ENST00000409885.1
glutamate-rich 2
chr2_+_64068116 0.31 ENST00000480679.1
UDP-glucose pyrophosphorylase 2
chr18_+_61575200 0.31 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr7_-_22234381 0.30 ENST00000458533.1
Rap guanine nucleotide exchange factor (GEF) 5
chr8_-_91657740 0.30 ENST00000422900.1
transmembrane protein 64
chr11_+_114271314 0.30 ENST00000541475.1
RNA binding motif protein 7
chr6_-_26189304 0.30 ENST00000340756.2
histone cluster 1, H4d
chr11_+_114549108 0.30 ENST00000389586.4
ENST00000375475.5
neurexophilin and PC-esterase domain family, member 2
chr19_-_43702231 0.29 ENST00000597374.1
ENST00000599371.1
pregnancy specific beta-1-glycoprotein 4
chr3_-_176914238 0.29 ENST00000430069.1
ENST00000428970.1
transducin (beta)-like 1 X-linked receptor 1
chr4_+_74718906 0.29 ENST00000226524.3
platelet factor 4 variant 1
chr4_-_15683118 0.28 ENST00000507899.1
ENST00000510802.1
F-box and leucine-rich repeat protein 5
chr1_+_110254850 0.28 ENST00000369812.5
ENST00000256593.3
ENST00000369813.1
glutathione S-transferase mu 5
chr1_-_108231101 0.28 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr12_+_64798095 0.28 ENST00000332707.5
exportin, tRNA
chr4_-_123843597 0.27 ENST00000510735.1
ENST00000304430.5
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr17_-_28618867 0.27 ENST00000394819.3
ENST00000577623.1
bleomycin hydrolase
chrX_+_155110956 0.27 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
vesicle-associated membrane protein 7
chr6_-_109330702 0.27 ENST00000356644.7
sestrin 1
chr15_+_23810903 0.27 ENST00000564592.1
makorin ring finger protein 3
chr5_+_94890778 0.26 ENST00000380009.4
arylsulfatase family, member K
chr6_+_27215471 0.26 ENST00000421826.2
protease, serine, 16 (thymus)
chr4_+_26585686 0.26 ENST00000505206.1
ENST00000511789.1
TBC1 domain family, member 19
chr5_-_74162739 0.26 ENST00000513277.1
family with sequence similarity 169, member A
chr5_-_111093167 0.26 ENST00000446294.2
ENST00000419114.2
neuronal regeneration related protein
chr4_-_89442940 0.26 ENST00000527353.1
phosphatidylinositol glycan anchor biosynthesis, class Y
chr7_-_5465045 0.26 ENST00000399434.2
trinucleotide repeat containing 18
chr19_+_15751689 0.26 ENST00000586182.2
ENST00000591058.1
ENST00000221307.8
cytochrome P450, family 4, subfamily F, polypeptide 3
chr7_-_100844193 0.25 ENST00000440203.2
ENST00000379423.3
ENST00000223114.4
monoacylglycerol O-acyltransferase 3
chr10_-_116444371 0.25 ENST00000533213.2
ENST00000369252.4
actin binding LIM protein 1
chr15_-_66858298 0.25 ENST00000537670.1
lactase-like
chr14_+_37131058 0.25 ENST00000361487.6
paired box 9
chrX_+_22050546 0.25 ENST00000379374.4
phosphate regulating endopeptidase homolog, X-linked
chr12_-_51785083 0.25 ENST00000603563.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr5_-_176433565 0.25 ENST00000428382.2
ubiquitin interaction motif containing 1
chr12_-_123215306 0.25 ENST00000356987.2
ENST00000436083.2
hydroxycarboxylic acid receptor 1
chr10_-_134145321 0.25 ENST00000368625.4
ENST00000368619.3
ENST00000456004.1
ENST00000368620.2
serine/threonine kinase 32C
chr6_+_7590413 0.25 ENST00000342415.5
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr21_+_27543175 0.25 ENST00000608591.1
ENST00000609365.1
AP000230.1
chr10_+_88854926 0.25 ENST00000298784.1
ENST00000298786.4
family with sequence similarity 35, member A
chr20_-_1569278 0.24 ENST00000262929.5
ENST00000567028.1
signal-regulatory protein beta 1
Uncharacterized protein
chr11_-_10879572 0.24 ENST00000413761.2
zinc finger, BED-type containing 5
chr13_+_108921977 0.24 ENST00000430559.1
ENST00000375887.4
tumor necrosis factor (ligand) superfamily, member 13b
chr12_-_75784669 0.24 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
calcyphosine 2
chr22_+_21133469 0.24 ENST00000406799.1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr12_+_105501487 0.24 ENST00000332180.5
KIAA1033
chrX_-_119709637 0.24 ENST00000404115.3
cullin 4B
chrX_-_14891150 0.24 ENST00000452869.1
ENST00000398334.1
ENST00000324138.3
Fanconi anemia, complementation group B
chr12_+_32655048 0.24 ENST00000427716.2
ENST00000266482.3
FYVE, RhoGEF and PH domain containing 4
chr16_-_3350614 0.23 ENST00000268674.2
tigger transposable element derived 7
chr5_+_71616188 0.23 ENST00000380639.5
ENST00000543322.1
ENST00000503868.1
ENST00000510676.2
ENST00000536805.1
pentatricopeptide repeat domain 2
chr12_-_91573132 0.23 ENST00000550563.1
ENST00000546370.1
decorin
chr14_-_58893876 0.22 ENST00000555097.1
ENST00000555404.1
translocase of inner mitochondrial membrane 9 homolog (yeast)
chrX_-_63005405 0.22 ENST00000374878.1
ENST00000437457.2
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr12_+_97306295 0.22 ENST00000457368.2
neural precursor cell expressed, developmentally down-regulated 1
chr6_+_88299833 0.22 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
origin recognition complex, subunit 3
chr9_-_119449483 0.22 ENST00000288520.5
ENST00000358637.4
ENST00000341734.4
astrotactin 2
chr19_-_12444306 0.22 ENST00000594577.1
ENST00000601858.1
zinc finger protein 563
chr11_+_27076764 0.22 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr10_-_13544945 0.22 ENST00000378605.3
ENST00000341083.3
BEN domain containing 7
chr8_+_97773202 0.22 ENST00000519484.1
carboxypeptidase Q
chr20_+_12989895 0.22 ENST00000450297.1
serine palmitoyltransferase, long chain base subunit 3
chr14_+_58894103 0.22 ENST00000354386.6
ENST00000556134.1
KIAA0586
chr4_+_154125565 0.21 ENST00000338700.5
tripartite motif containing 2
chr11_+_1855645 0.21 ENST00000381968.3
ENST00000381978.3
synaptotagmin VIII
chr22_-_36600849 0.21 ENST00000429038.2
ENST00000457630.2
ENST00000419360.1
ENST00000436763.1
ENST00000404685.3
ENST00000405511.1
ENST00000352371.1
ENST00000332987.1
ENST00000449084.1
apolipoprotein L, 4
chr10_+_38383255 0.21 ENST00000351773.3
ENST00000361085.5
zinc finger protein 37A
chr12_-_110511424 0.21 ENST00000548191.1
chromosome 12 open reading frame 76
chr12_-_51785393 0.21 ENST00000605138.1
ENST00000604381.1
ENST00000605055.1
ENST00000605617.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr5_+_94890840 0.20 ENST00000504763.1
arylsulfatase family, member K
chr3_-_176914191 0.20 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
transducin (beta)-like 1 X-linked receptor 1
chr4_+_57843876 0.20 ENST00000450656.1
ENST00000381227.1
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr11_-_114271139 0.20 ENST00000325636.4
chromosome 11 open reading frame 71
chr1_-_62785054 0.20 ENST00000371153.4
KN motif and ankyrin repeat domains 4
chr6_+_159290917 0.20 ENST00000367072.1
chromosome 6 open reading frame 99
chr6_-_31088214 0.20 ENST00000376288.2
corneodesmosin
chr11_-_10879593 0.20 ENST00000528289.1
ENST00000432999.2
zinc finger, BED-type containing 5
chr17_+_60758814 0.20 ENST00000579432.1
ENST00000446119.2
mannose receptor, C type 2
chr12_+_75784850 0.20 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLI pathogenesis-related 1 like 2
chr9_-_14693417 0.20 ENST00000380916.4
zinc finger, DHHC-type containing 21
chr11_+_34938119 0.20 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
pyruvate dehydrogenase complex, component X
chr2_-_46844159 0.20 ENST00000474980.1
ENST00000306465.4
phosphatidylinositol glycan anchor biosynthesis, class F
chr4_+_95128996 0.19 ENST00000457823.2
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_+_22351977 0.19 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
long intergenic non-protein coding RNA 339
chr10_+_90750493 0.19 ENST00000357339.2
ENST00000355279.2
Fas cell surface death receptor
chr22_+_22673051 0.19 ENST00000390289.2
immunoglobulin lambda variable 5-52
chr5_+_139027877 0.19 ENST00000302517.3
CXXC finger protein 5
chr13_-_53024725 0.19 ENST00000378060.4
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr22_+_20905422 0.19 ENST00000424287.1
ENST00000423862.1
mediator complex subunit 15
chr12_+_111051902 0.19 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
tectonic family member 1
chr13_-_33112899 0.19 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
NEDD4 binding protein 2-like 2
chr5_+_110427983 0.19 ENST00000513710.2
ENST00000505303.1
WD repeat domain 36
chr15_+_34517251 0.19 ENST00000559421.1
ER membrane protein complex subunit 4
chr19_+_6531010 0.18 ENST00000245817.3
tumor necrosis factor (ligand) superfamily, member 9
chr5_-_74162605 0.18 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
family with sequence similarity 169, member A
chr20_+_12989822 0.18 ENST00000378194.4
serine palmitoyltransferase, long chain base subunit 3
chr8_-_27469383 0.18 ENST00000519742.1
clusterin
chr4_+_80584903 0.18 ENST00000506460.1
RP11-452C8.1
chr13_+_24844857 0.18 ENST00000409126.1
ENST00000343003.6
spermatogenesis associated 13
chr2_-_46844242 0.18 ENST00000281382.6
phosphatidylinositol glycan anchor biosynthesis, class F
chr1_-_229644034 0.18 ENST00000366678.3
ENST00000261396.3
ENST00000537506.1
nucleoporin 133kDa
chr1_-_222014008 0.18 ENST00000431729.1
RP11-191N8.2
chr4_+_95129061 0.18 ENST00000354268.4
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_+_15986364 0.18 ENST00000345034.1
regulatory solute carrier protein, family 1, member 1
chr20_-_1569351 0.18 ENST00000563840.1
signal-regulatory protein beta 1
chr17_+_42248063 0.18 ENST00000293414.1
ankyrin repeat and SOCS box containing 16
chr18_+_11851383 0.18 ENST00000526991.2
charged multivesicular body protein 1B
chr3_+_101292939 0.18 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
PEST proteolytic signal containing nuclear protein
chr2_+_46844290 0.18 ENST00000238892.3
cysteine-rich PDZ-binding protein
chr2_-_74648702 0.18 ENST00000518863.1
chromosome 2 open reading frame 81
chr12_-_118796910 0.17 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr11_-_93583697 0.17 ENST00000409977.1
V-set and transmembrane domain containing 5
chr2_+_64068074 0.17 ENST00000394417.2
ENST00000484142.1
ENST00000482668.1
ENST00000467648.2
UDP-glucose pyrophosphorylase 2
chr1_-_23694794 0.17 ENST00000374608.3
zinc finger protein 436
chr3_+_108308559 0.17 ENST00000486815.1
DAZ interacting zinc finger protein 3
chr6_-_71666732 0.17 ENST00000230053.6
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr8_+_97773457 0.17 ENST00000521142.1
carboxypeptidase Q
chr16_-_11723066 0.16 ENST00000576036.1
lipopolysaccharide-induced TNF factor
chr2_+_163200598 0.16 ENST00000437150.2
ENST00000453113.2
grancalcin, EF-hand calcium binding protein
chr4_+_140222609 0.16 ENST00000296543.5
ENST00000398947.1
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr6_+_31638156 0.16 ENST00000409525.1
lymphocyte antigen 6 complex, locus G5B
chr18_+_32173276 0.16 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr8_+_48920960 0.16 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
ubiquitin-conjugating enzyme E2 variant 2
chr11_+_45168182 0.16 ENST00000526442.1
PR domain containing 11
chr5_-_94890648 0.16 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
tetratricopeptide repeat domain 37
chr3_+_44771088 0.16 ENST00000396048.2
zinc finger protein 501
chr7_+_2695726 0.16 ENST00000429448.1
tweety family member 3
chr20_+_61867235 0.16 ENST00000342412.6
ENST00000217169.3
baculoviral IAP repeat containing 7
chr1_+_196788887 0.16 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr4_+_15683404 0.16 ENST00000422728.2
family with sequence similarity 200, member B
chr5_+_140019079 0.16 ENST00000252100.6
transmembrane and coiled-coil domains 6
chr17_+_6900201 0.15 ENST00000480801.1
arachidonate 12-lipoxygenase
chr18_+_32290218 0.15 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
dystrobrevin, alpha
chr1_+_167599532 0.15 ENST00000537350.1
RCSD domain containing 1
chr11_+_121447469 0.15 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr15_+_90895471 0.15 ENST00000354377.3
ENST00000379090.5
zinc finger protein 774
chr12_-_53594227 0.15 ENST00000550743.2
integrin, beta 7
chr2_+_103089756 0.15 ENST00000295269.4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr6_-_143771799 0.15 ENST00000237283.8
adenosine deaminase, tRNA-specific 2
chr12_+_133613937 0.15 ENST00000539354.1
ENST00000542874.1
ENST00000438628.2
zinc finger protein 84
chr11_-_62379752 0.15 ENST00000466671.1
ENST00000466886.1
echinoderm microtubule associated protein like 3
chr4_-_42659102 0.15 ENST00000264449.10
ENST00000510289.1
ENST00000381668.5
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFF_MAFG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.3 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.8 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.2 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.6 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.4 GO:0019236 response to pheromone(GO:0019236)
0.1 0.2 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.1 0.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.1 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.5 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 1.0 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.5 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.6 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.2 GO:1902997 protein retention in Golgi apparatus(GO:0045053) regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.3 GO:1901523 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1 0.2 GO:0003335 corneocyte development(GO:0003335)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.3 GO:0060356 leucine import(GO:0060356)
0.0 0.2 GO:0031081 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.0 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.4 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:2001303 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.3 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.7 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.7 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.5 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.2 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.2 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.7 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.5 GO:0042117 monocyte activation(GO:0042117)
0.0 0.1 GO:0070893 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.0 0.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:0033241 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:1902996 regulation of neuronal signal transduction(GO:1902847) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 1.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.1 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.1 GO:0071400 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.0 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.0 GO:0018307 enzyme active site formation(GO:0018307)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.9 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.0 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.0 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 1.0 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 0.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.0 0.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.7 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.2 0.5 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.4 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.3 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.6 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.5 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0016826 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.0 0.2 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.0 0.2 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.7 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.0 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.0 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.1 GO:0047718 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 0.0 GO:0000035 acyl binding(GO:0000035)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex