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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MAX_TFEB

Z-value: 0.48

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Transcription factors associated with MAX_TFEB

Gene Symbol Gene ID Gene Info
MAX
ENSG00000125952.14 MYC associated factor X
TFEB
ENSG00000112561.13 transcription factor EB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFEBhg19_v2_chr6_-_41673552_416736780.786.7e-02Click!
MAXhg19_v2_chr14_-_65569244_65569413-0.473.5e-01Click!

Activity profile of MAX_TFEB motif

Sorted Z-values of MAX_TFEB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_103876528 0.86 ENST00000522939.1
ENST00000524007.1
KB-1507C5.2
HCG15011, isoform CRA_a; Protein LOC100996457
chr5_+_133706865 0.53 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr15_-_65282045 0.51 ENST00000558765.1
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr6_-_109703663 0.49 ENST00000368961.5
CD164
CD164 molecule, sialomucin
chrX_-_119693745 0.47 ENST00000371323.2
CUL4B
cullin 4B
chr14_-_54955721 0.46 ENST00000554908.1
GMFB
glia maturation factor, beta
chr2_+_240323439 0.44 ENST00000428471.1
ENST00000413029.1
AC062017.1
Uncharacterized protein
chr5_+_133707252 0.43 ENST00000506787.1
ENST00000507277.1
UBE2B
ubiquitin-conjugating enzyme E2B
chr5_+_110074685 0.41 ENST00000355943.3
ENST00000447245.2
SLC25A46
solute carrier family 25, member 46
chr10_-_46089939 0.41 ENST00000453980.3
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr19_+_5681011 0.38 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr11_-_18343725 0.38 ENST00000531848.1
HPS5
Hermansky-Pudlak syndrome 5
chr6_-_33385854 0.37 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr18_+_9136758 0.36 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12
ankyrin repeat domain 12
chr4_-_47465666 0.35 ENST00000381571.4
COMMD8
COMM domain containing 8
chr14_-_54955376 0.34 ENST00000553333.1
GMFB
glia maturation factor, beta
chr3_+_19988736 0.34 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr1_+_52521928 0.34 ENST00000489308.2
BTF3L4
basic transcription factor 3-like 4
chr8_-_54755789 0.33 ENST00000359530.2
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr2_-_40006289 0.33 ENST00000260619.6
ENST00000454352.2
THUMPD2
THUMP domain containing 2
chr15_-_50978965 0.32 ENST00000560955.1
ENST00000313478.7
TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr1_+_42921761 0.32 ENST00000372562.1
PPCS
phosphopantothenoylcysteine synthetase
chr15_-_65281775 0.32 ENST00000433215.2
ENST00000558415.1
ENST00000557795.1
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr4_-_76439596 0.31 ENST00000451788.1
ENST00000512706.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr2_-_176867534 0.31 ENST00000445472.1
KIAA1715
KIAA1715
chr6_-_109703634 0.31 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164
CD164 molecule, sialomucin
chrX_-_15872914 0.31 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr9_+_74526532 0.31 ENST00000486911.2
C9orf85
chromosome 9 open reading frame 85
chr3_-_113464906 0.31 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr10_+_70883908 0.29 ENST00000263559.6
ENST00000395098.1
ENST00000546041.1
ENST00000541711.1
VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr12_+_56110247 0.29 ENST00000551926.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr9_+_74526384 0.29 ENST00000334731.2
ENST00000377031.3
C9orf85
chromosome 9 open reading frame 85
chr4_-_76439483 0.29 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr14_+_77564440 0.28 ENST00000361786.2
ENST00000555437.1
ENST00000555611.1
ENST00000554658.1
KIAA1737
CLOCK-interacting pacemaker
chr9_-_103115135 0.28 ENST00000537512.1
TEX10
testis expressed 10
chr3_-_195163584 0.28 ENST00000439666.1
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr6_-_84937314 0.28 ENST00000257766.4
ENST00000403245.3
KIAA1009
KIAA1009
chr3_+_112280857 0.28 ENST00000492406.1
ENST00000468642.1
SLC35A5
solute carrier family 35, member A5
chr14_-_81687197 0.28 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr2_-_148778258 0.27 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4
origin recognition complex, subunit 4
chrX_+_102585124 0.27 ENST00000332431.4
ENST00000372666.1
TCEAL7
transcription elongation factor A (SII)-like 7
chr10_+_23728198 0.26 ENST00000376495.3
OTUD1
OTU domain containing 1
chr3_+_184530173 0.26 ENST00000453056.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr6_+_7590413 0.26 ENST00000342415.5
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr2_-_40006357 0.26 ENST00000505747.1
THUMPD2
THUMP domain containing 2
chr4_-_99850243 0.25 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E
eukaryotic translation initiation factor 4E
chr19_-_49137790 0.25 ENST00000599385.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr2_+_46926326 0.25 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr14_-_35183755 0.25 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr6_-_109703600 0.25 ENST00000512821.1
CD164
CD164 molecule, sialomucin
chr6_-_33385902 0.24 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr14_+_64970427 0.24 ENST00000553583.1
ZBTB1
zinc finger and BTB domain containing 1
chr1_+_40627038 0.24 ENST00000372771.4
RLF
rearranged L-myc fusion
chr1_-_39325431 0.24 ENST00000373001.3
RRAGC
Ras-related GTP binding C
chr3_-_20227619 0.23 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
SGOL1
shugoshin-like 1 (S. pombe)
chr15_+_82555125 0.23 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B
family with sequence similarity 154, member B
chr17_+_62223320 0.23 ENST00000580828.1
ENST00000582965.1
SNORA76
small nucleolar RNA, H/ACA box 76
chr21_-_38445297 0.23 ENST00000430792.1
ENST00000399103.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr17_-_7137582 0.23 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr21_-_38445011 0.23 ENST00000464265.1
ENST00000399102.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr6_-_80657292 0.23 ENST00000369816.4
ELOVL4
ELOVL fatty acid elongase 4
chr8_+_109455830 0.23 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr7_+_116593536 0.23 ENST00000417919.1
ST7
suppression of tumorigenicity 7
chr4_-_54930790 0.22 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr3_-_196987309 0.22 ENST00000453607.1
DLG1
discs, large homolog 1 (Drosophila)
chr8_-_54755459 0.22 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr4_+_56719782 0.21 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
EXOC1
exocyst complex component 1
chr13_+_113951607 0.21 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr17_-_6915646 0.21 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2
Uncharacterized protein
chr4_+_141264597 0.21 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC
short coiled-coil protein
chr3_+_127317705 0.21 ENST00000480910.1
MCM2
minichromosome maintenance complex component 2
chr12_+_56109926 0.21 ENST00000547076.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr11_+_67159416 0.21 ENST00000307980.2
ENST00000544620.1
RAD9A
RAD9 homolog A (S. pombe)
chr4_-_166034004 0.21 ENST00000505095.1
TMEM192
transmembrane protein 192
chrX_+_95939638 0.20 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2
diaphanous-related formin 2
chr1_-_183604794 0.20 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr9_+_92219919 0.20 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr1_+_109419804 0.20 ENST00000435475.1
GPSM2
G-protein signaling modulator 2
chr12_+_6833323 0.20 ENST00000544725.1
COPS7A
COP9 signalosome subunit 7A
chr8_+_9009296 0.20 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr1_+_52521797 0.19 ENST00000313334.8
BTF3L4
basic transcription factor 3-like 4
chr7_-_108209897 0.19 ENST00000313516.5
THAP5
THAP domain containing 5
chr2_+_46926048 0.19 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr4_-_84376953 0.19 ENST00000510985.1
ENST00000295488.3
HELQ
helicase, POLQ-like
chr14_-_35591433 0.19 ENST00000261475.5
ENST00000555644.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr18_+_77867177 0.18 ENST00000560752.1
ADNP2
ADNP homeobox 2
chr2_-_148778323 0.18 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr12_-_76953513 0.18 ENST00000547540.1
OSBPL8
oxysterol binding protein-like 8
chr5_+_41904431 0.18 ENST00000381647.2
C5orf51
chromosome 5 open reading frame 51
chr17_-_7137857 0.18 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr8_+_120220561 0.18 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr10_-_93392811 0.18 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr1_+_222885884 0.17 ENST00000340934.5
BROX
BRO1 domain and CAAX motif containing
chr1_+_42922173 0.17 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
PPCS
phosphopantothenoylcysteine synthetase
chr10_-_76995675 0.17 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr9_+_96928516 0.17 ENST00000602703.1
RP11-2B6.3
RP11-2B6.3
chr1_+_100436065 0.17 ENST00000370153.1
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr4_+_76439665 0.17 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP6
THAP domain containing 6
chr12_+_64845660 0.17 ENST00000331710.5
TBK1
TANK-binding kinase 1
chr6_+_123110302 0.17 ENST00000368440.4
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr1_-_222886526 0.17 ENST00000541237.1
AIDA
axin interactor, dorsalization associated
chr3_-_142720267 0.17 ENST00000597953.1
RP11-91G21.1
RP11-91G21.1
chr3_+_140660634 0.16 ENST00000446041.2
ENST00000507429.1
ENST00000324194.6
SLC25A36
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr8_-_75233563 0.16 ENST00000342232.4
JPH1
junctophilin 1
chr2_+_172864490 0.16 ENST00000315796.4
METAP1D
methionyl aminopeptidase type 1D (mitochondrial)
chr1_-_222885770 0.16 ENST00000355727.2
ENST00000340020.6
AIDA
axin interactor, dorsalization associated
chr11_+_62538775 0.16 ENST00000294168.3
ENST00000526261.1
TAF6L
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr12_-_76953284 0.16 ENST00000547544.1
ENST00000393249.2
OSBPL8
oxysterol binding protein-like 8
chr3_-_122512619 0.16 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr13_+_42846272 0.16 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr6_+_87865262 0.16 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr3_-_57678772 0.16 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr18_+_9708162 0.16 ENST00000578921.1
RAB31
RAB31, member RAS oncogene family
chr3_-_113465065 0.15 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr12_-_76477707 0.15 ENST00000551992.1
NAP1L1
nucleosome assembly protein 1-like 1
chr1_+_89149905 0.15 ENST00000316005.7
ENST00000370521.3
ENST00000370505.3
PKN2
protein kinase N2
chr9_-_6015607 0.15 ENST00000259569.5
RANBP6
RAN binding protein 6
chr11_-_18343669 0.15 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5
Hermansky-Pudlak syndrome 5
chr9_-_123476612 0.15 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr10_-_46090334 0.15 ENST00000395771.3
ENST00000319836.3
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr17_-_77967433 0.15 ENST00000571872.1
TBC1D16
TBC1 domain family, member 16
chr18_-_29522989 0.15 ENST00000582539.1
ENST00000283351.4
ENST00000582513.1
TRAPPC8
trafficking protein particle complex 8
chr11_+_9406169 0.15 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr11_-_85780086 0.15 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr14_-_35183886 0.15 ENST00000298159.6
CFL2
cofilin 2 (muscle)
chr15_-_65282274 0.15 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr3_-_101395936 0.15 ENST00000461821.1
ZBTB11
zinc finger and BTB domain containing 11
chr6_+_123110465 0.15 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr3_-_197025447 0.15 ENST00000346964.2
ENST00000357674.4
ENST00000314062.3
ENST00000448528.2
ENST00000419553.1
DLG1
discs, large homolog 1 (Drosophila)
chr7_-_27179814 0.15 ENST00000522788.1
ENST00000521779.1
HOXA3
homeobox A3
chrX_-_34675391 0.15 ENST00000275954.3
TMEM47
transmembrane protein 47
chr9_-_103115185 0.15 ENST00000374902.4
TEX10
testis expressed 10
chr12_+_56109810 0.14 ENST00000550412.1
ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
RP11-644F5.10
BLOC1S1
Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 1
chr10_-_32217717 0.14 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
ARHGAP12
Rho GTPase activating protein 12
chr3_+_133292759 0.14 ENST00000431519.2
CDV3
CDV3 homolog (mouse)
chr2_-_238499337 0.14 ENST00000411462.1
ENST00000409822.1
RAB17
RAB17, member RAS oncogene family
chr6_+_151773583 0.14 ENST00000545879.1
C6orf211
chromosome 6 open reading frame 211
chr3_-_197024965 0.14 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chr1_-_68962744 0.14 ENST00000525124.1
DEPDC1
DEP domain containing 1
chr7_+_36429424 0.14 ENST00000396068.2
ANLN
anillin, actin binding protein
chrX_-_100604184 0.14 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr5_+_56205878 0.14 ENST00000423328.1
SETD9
SET domain containing 9
chr17_+_49337881 0.14 ENST00000225298.7
UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr17_-_49337392 0.14 ENST00000376381.2
ENST00000586178.1
MBTD1
mbt domain containing 1
chr3_-_45883558 0.14 ENST00000445698.1
ENST00000296135.6
LZTFL1
leucine zipper transcription factor-like 1
chrX_+_150565038 0.14 ENST00000370361.1
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr1_+_15853308 0.14 ENST00000375838.1
ENST00000375847.3
ENST00000375849.1
DNAJC16
DnaJ (Hsp40) homolog, subfamily C, member 16
chr5_+_110427983 0.13 ENST00000513710.2
ENST00000505303.1
WDR36
WD repeat domain 36
chr2_+_232575168 0.13 ENST00000440384.1
PTMA
prothymosin, alpha
chr16_-_81129845 0.13 ENST00000569885.1
ENST00000566566.1
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr14_-_54420133 0.13 ENST00000559501.1
ENST00000558984.1
BMP4
bone morphogenetic protein 4
chr3_+_140660743 0.13 ENST00000453248.2
SLC25A36
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr14_-_35591156 0.13 ENST00000554361.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr3_+_19988566 0.13 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chrX_+_95939711 0.13 ENST00000373049.4
ENST00000324765.8
DIAPH2
diaphanous-related formin 2
chr18_+_20715416 0.13 ENST00000580153.1
CABLES1
Cdk5 and Abl enzyme substrate 1
chr21_+_38445539 0.13 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr17_-_19880992 0.13 ENST00000395536.3
ENST00000576896.1
ENST00000225737.6
AKAP10
A kinase (PRKA) anchor protein 10
chr11_-_113746212 0.13 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
USP28
ubiquitin specific peptidase 28
chr13_-_79233314 0.13 ENST00000282003.6
RNF219
ring finger protein 219
chr6_-_33385823 0.13 ENST00000494751.1
ENST00000374496.3
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr8_-_95961578 0.13 ENST00000448464.2
ENST00000342697.4
TP53INP1
tumor protein p53 inducible nuclear protein 1
chr6_+_139349817 0.13 ENST00000367660.3
ABRACL
ABRA C-terminal like
chr7_+_92861653 0.13 ENST00000251739.5
ENST00000305866.5
ENST00000544910.1
ENST00000541136.1
ENST00000458530.1
ENST00000535481.1
ENST00000317751.6
CCDC132
coiled-coil domain containing 132
chr8_+_104426942 0.13 ENST00000297579.5
DCAF13
DDB1 and CUL4 associated factor 13
chr10_+_112327425 0.13 ENST00000361804.4
SMC3
structural maintenance of chromosomes 3
chr9_-_123476719 0.13 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr2_-_55459485 0.13 ENST00000451916.1
CLHC1
clathrin heavy chain linker domain containing 1
chr20_+_17550691 0.13 ENST00000474024.1
DSTN
destrin (actin depolymerizing factor)
chr12_+_28343353 0.12 ENST00000539107.1
CCDC91
coiled-coil domain containing 91
chr1_-_71546690 0.12 ENST00000254821.6
ZRANB2
zinc finger, RAN-binding domain containing 2
chr12_-_42632016 0.12 ENST00000442791.3
ENST00000327791.4
ENST00000534854.2
ENST00000380788.3
ENST00000380790.4
YAF2
YY1 associated factor 2
chr19_-_11545920 0.12 ENST00000356392.4
ENST00000591179.1
CCDC151
coiled-coil domain containing 151
chr12_-_108154705 0.12 ENST00000547188.1
PRDM4
PR domain containing 4
chr7_+_108210012 0.12 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr22_-_36903101 0.12 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr17_+_42977122 0.12 ENST00000412523.2
ENST00000331733.4
ENST00000417826.2
FAM187A
CCDC103
family with sequence similarity 187, member A
coiled-coil domain containing 103
chr5_-_176730733 0.12 ENST00000504395.1
RAB24
RAB24, member RAS oncogene family
chrX_+_72783026 0.12 ENST00000373504.6
ENST00000373502.5
CHIC1
cysteine-rich hydrophobic domain 1
chr11_+_18344106 0.12 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr11_+_114310237 0.12 ENST00000539119.1
REXO2
RNA exonuclease 2
chr7_+_36429409 0.12 ENST00000265748.2
ANLN
anillin, actin binding protein
chr1_+_17248418 0.12 ENST00000375541.5
CROCC
ciliary rootlet coiled-coil, rootletin
chr2_-_198364581 0.12 ENST00000428204.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chrX_-_102531717 0.12 ENST00000372680.1
TCEAL5
transcription elongation factor A (SII)-like 5
chr11_+_120894781 0.12 ENST00000529397.1
ENST00000528512.1
ENST00000422003.2
TBCEL
tubulin folding cofactor E-like
chr17_-_57184260 0.12 ENST00000376149.3
ENST00000393066.3
TRIM37
tripartite motif containing 37
chr19_+_8386371 0.12 ENST00000600659.2
RPS28
ribosomal protein S28
chr7_+_12726474 0.12 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ARL4A
ADP-ribosylation factor-like 4A
chr22_-_42343117 0.12 ENST00000407253.3
ENST00000215980.5
CENPM
centromere protein M
chr16_+_24550857 0.12 ENST00000568015.1
RBBP6
retinoblastoma binding protein 6
chr7_+_74379083 0.12 ENST00000361825.7
GATSL1
GATS protein-like 1
chr11_-_47470682 0.11 ENST00000529341.1
ENST00000352508.3
RAPSN
receptor-associated protein of the synapse
chr12_+_64798095 0.11 ENST00000332707.5
XPOT
exportin, tRNA
chr9_+_130860583 0.11 ENST00000373064.5
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr3_+_50654821 0.11 ENST00000457064.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr16_+_57220193 0.11 ENST00000564435.1
ENST00000562959.1
ENST00000394420.4
ENST00000568505.2
ENST00000537866.1
RSPRY1
ring finger and SPRY domain containing 1
chr12_-_46663734 0.11 ENST00000550173.1
SLC38A1
solute carrier family 38, member 1
chr17_-_18266818 0.11 ENST00000583780.1
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr11_+_107879459 0.11 ENST00000393094.2
CUL5
cullin 5

Network of associatons between targets according to the STRING database.

First level regulatory network of MAX_TFEB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 0.2 GO:0010737 protein kinase A signaling(GO:0010737) regulation of protein kinase A signaling(GO:0010738)
0.1 0.3 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961) calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.4 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.4 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.8 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.3 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.1 0.3 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.4 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.5 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.6 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.3 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 0.3 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.4 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.2 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.5 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.1 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.7 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.1 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.0 0.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.0 0.1 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.2 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0072096 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.8 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.0 0.1 GO:0043181 vacuolar sequestering(GO:0043181)
0.0 0.1 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.2 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:0042414 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) epinephrine metabolic process(GO:0042414) cellular response to lead ion(GO:0071284)
0.0 0.1 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:0050787 detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.0 0.2 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.0 GO:1903371 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.0 GO:0044209 AMP salvage(GO:0044209)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.0 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0 0.0 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.0 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.6 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.0 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.8 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 1.0 GO:0033503 HULC complex(GO:0033503)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.6 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629) omegasome membrane(GO:1903349)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.0 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.0 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 1.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.0 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.0 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo