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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MSX2

Z-value: 0.31

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Transcription factors associated with MSX2

Gene Symbol Gene ID Gene Info
ENSG00000120149.7 msh homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSX2hg19_v2_chr5_+_174151536_174151610-0.796.1e-02Click!

Activity profile of MSX2 motif

Sorted Z-values of MSX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_88200641 0.24 ENST00000556168.1
RP11-1152H15.1
chr1_+_152943122 0.19 ENST00000328051.2
small proline-rich protein 4
chr3_-_180397256 0.11 ENST00000442201.2
coiled-coil domain containing 39
chr12_+_64798826 0.10 ENST00000540203.1
exportin, tRNA
chr1_+_81001398 0.10 ENST00000418041.1
ENST00000443104.1
RP5-887A10.1
chr20_-_50418972 0.09 ENST00000395997.3
spalt-like transcription factor 4
chr3_-_112127981 0.08 ENST00000486726.2
RP11-231E6.1
chr7_-_2883650 0.08 ENST00000544127.1
guanine nucleotide binding protein (G protein) alpha 12
chr16_-_18923035 0.08 ENST00000563836.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr6_+_130339710 0.08 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr12_-_9102224 0.08 ENST00000543845.1
ENST00000544245.1
mannose-6-phosphate receptor (cation dependent)
chr8_-_117886563 0.07 ENST00000519837.1
ENST00000522699.1
RAD21 homolog (S. pombe)
chr1_-_151762900 0.07 ENST00000440583.2
tudor and KH domain containing
chr16_+_58783542 0.07 ENST00000500117.1
ENST00000565722.1
RP11-410D17.2
chr10_-_99205607 0.06 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
exosome component 1
chr3_-_120400960 0.06 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr3_-_141747950 0.06 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr11_+_17298543 0.06 ENST00000533926.1
nucleobindin 2
chr18_+_63273310 0.06 ENST00000579862.1
RP11-775G23.1
chr4_-_69434245 0.06 ENST00000317746.2
UDP glucuronosyltransferase 2 family, polypeptide B17
chr7_+_99717230 0.05 ENST00000262932.3
canopy FGF signaling regulator 4
chr1_+_44115814 0.05 ENST00000372396.3
lysine (K)-specific demethylase 4A
chr19_+_41869894 0.05 ENST00000413014.2
transmembrane protein 91
chr6_-_167040731 0.05 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr10_+_99205894 0.05 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
zinc finger, DHHC-type containing 16
chr7_-_2883928 0.05 ENST00000275364.3
guanine nucleotide binding protein (G protein) alpha 12
chr10_+_99205959 0.04 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
zinc finger, DHHC-type containing 16
chr17_-_43045439 0.04 ENST00000253407.3
complement component 1, q subcomponent-like 1
chrX_+_77154935 0.04 ENST00000481445.1
cytochrome c oxidase subunit VIIb
chr12_-_120315074 0.04 ENST00000261833.7
ENST00000392521.2
citron (rho-interacting, serine/threonine kinase 21)
chr3_-_120003941 0.04 ENST00000464295.1
G protein-coupled receptor 156
chr12_-_95397442 0.04 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr1_-_151762943 0.04 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
tudor and KH domain containing
chr12_-_9102549 0.04 ENST00000000412.3
mannose-6-phosphate receptor (cation dependent)
chr6_-_116866773 0.03 ENST00000368602.3
trafficking protein particle complex 3-like
chr12_-_57039739 0.03 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr3_+_113251143 0.03 ENST00000264852.4
ENST00000393830.3
SID1 transmembrane family, member 1
chr15_-_37393406 0.03 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr1_+_27158483 0.03 ENST00000374141.2
zinc finger, DHHC-type containing 18
chr20_-_54967187 0.03 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
aurora kinase A
chr11_+_108535752 0.03 ENST00000322536.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr1_-_151965048 0.03 ENST00000368809.1
S100 calcium binding protein A10
chr5_-_31532238 0.03 ENST00000507438.1
drosha, ribonuclease type III
chr5_+_95998070 0.03 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
calpastatin
chr1_-_47779762 0.03 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
SCL/TAL1 interrupting locus
chr5_-_132200477 0.03 ENST00000296875.2
growth differentiation factor 9
chr5_+_150639360 0.03 ENST00000523004.1
GM2 ganglioside activator
chr17_+_67759813 0.03 ENST00000587241.1
AC003051.1
chr20_+_54967663 0.03 ENST00000452950.1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr1_-_151431674 0.03 ENST00000531094.1
pogo transposable element with ZNF domain
chr6_-_167040693 0.03 ENST00000366863.2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_-_68698197 0.03 ENST00000370973.2
ENST00000370971.1
wntless Wnt ligand secretion mediator
chr9_+_34646624 0.03 ENST00000450095.2
ENST00000556278.1
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr20_-_50418947 0.03 ENST00000371539.3
spalt-like transcription factor 4
chr14_-_23504432 0.03 ENST00000425762.2
proteasome (prosome, macropain) subunit, beta type, 5
chr20_-_50722183 0.03 ENST00000371523.4
ZFP64 zinc finger protein
chr11_-_124981475 0.02 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr7_+_100183927 0.02 ENST00000241071.6
ENST00000360609.2
F-box protein 24
chr2_-_200335983 0.02 ENST00000457245.1
SATB homeobox 2
chr9_+_34646651 0.02 ENST00000378842.3
galactose-1-phosphate uridylyltransferase
chr12_+_54718904 0.02 ENST00000262061.2
ENST00000549043.1
ENST00000552218.1
ENST00000553231.1
ENST00000552362.1
ENST00000455864.2
ENST00000416254.2
ENST00000549116.1
ENST00000551779.1
coatomer protein complex, subunit zeta 1
chr5_+_95997885 0.02 ENST00000511097.2
calpastatin
chr17_-_12920907 0.02 ENST00000609757.1
ENST00000581499.2
ENST00000580504.1
elaC ribonuclease Z 2
chr16_+_69345243 0.02 ENST00000254950.11
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr1_-_36916066 0.02 ENST00000315643.9
organic solute carrier partner 1
chrX_-_48931648 0.02 ENST00000376386.3
ENST00000376390.4
PRA1 domain family, member 2
chr17_+_12569306 0.02 ENST00000425538.1
myocardin
chr11_-_71823715 0.02 ENST00000545944.1
ENST00000502597.2
anaphase promoting complex subunit 15
chr6_-_111927062 0.02 ENST00000359831.4
TRAF3 interacting protein 2
chr1_-_151431647 0.02 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
pogo transposable element with ZNF domain
chr5_-_31532160 0.02 ENST00000511367.2
ENST00000513349.1
drosha, ribonuclease type III
chr17_-_9929581 0.02 ENST00000437099.2
ENST00000396115.2
growth arrest-specific 7
chr4_-_69536346 0.02 ENST00000338206.5
UDP glucuronosyltransferase 2 family, polypeptide B15
chr2_+_150187020 0.02 ENST00000334166.4
LY6/PLAUR domain containing 6
chr1_-_158173659 0.02 ENST00000415019.1
RP11-404O13.5
chr7_-_99716940 0.02 ENST00000440225.1
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr14_-_23504337 0.02 ENST00000361611.6
proteasome (prosome, macropain) subunit, beta type, 5
chr7_+_134331550 0.02 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
2,3-bisphosphoglycerate mutase
chr6_+_30687978 0.02 ENST00000327892.8
ENST00000435534.1
tubulin, beta class I
chr17_+_12569472 0.01 ENST00000343344.4
myocardin
chrX_+_70752917 0.01 ENST00000373719.3
O-linked N-acetylglucosamine (GlcNAc) transferase
chr11_+_17298342 0.01 ENST00000530964.1
nucleobindin 2
chr1_+_151735431 0.01 ENST00000321531.5
ENST00000315067.8
ornithine decarboxylase antizyme 3
chr22_-_30960876 0.01 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
galactose-3-O-sulfotransferase 1
chr3_+_186353756 0.01 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
fetuin B
chr9_+_74729511 0.01 ENST00000545168.1
guanine deaminase
chr20_+_30467600 0.01 ENST00000375934.4
ENST00000375922.4
tubulin tyrosine ligase-like family, member 9
chr4_-_109684120 0.01 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ethanolamine-phosphate phospho-lyase
chr1_-_23694794 0.01 ENST00000374608.3
zinc finger protein 436
chr1_-_94050668 0.01 ENST00000539242.1
breast cancer anti-estrogen resistance 3
chrX_+_70752945 0.01 ENST00000373701.3
O-linked N-acetylglucosamine (GlcNAc) transferase
chr6_-_31830655 0.01 ENST00000375631.4
sialidase 1 (lysosomal sialidase)
chr7_+_130794846 0.01 ENST00000421797.2
muskelin 1, intracellular mediator containing kelch motifs
chr15_+_80351910 0.01 ENST00000261749.6
ENST00000561060.1
zinc finger, AN1-type domain 6
chr3_-_48672859 0.01 ENST00000395550.2
ENST00000455886.2
ENST00000431739.1
ENST00000426599.1
ENST00000383733.3
ENST00000420764.2
ENST00000337000.8
solute carrier family 26 (anion exchanger), member 6
chr20_+_49126881 0.01 ENST00000371621.3
ENST00000541713.1
protein tyrosine phosphatase, non-receptor type 1
chr6_+_160183492 0.01 ENST00000541436.1
acetyl-CoA acetyltransferase 2
chr11_-_71823796 0.01 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
anaphase promoting complex subunit 15
chr4_-_138453606 0.01 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr19_+_17378278 0.01 ENST00000596335.1
ENST00000601436.1
ENST00000595632.1
BRISC and BRCA1 A complex member 1
chr1_-_21377383 0.01 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr8_+_38831683 0.01 ENST00000302495.4
HtrA serine peptidase 4
chr1_-_68698222 0.01 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
wntless Wnt ligand secretion mediator
chr10_-_56561022 0.01 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
protocadherin-related 15
chr3_-_114866084 0.01 ENST00000357258.3
zinc finger and BTB domain containing 20
chr13_-_103389159 0.01 ENST00000322527.2
coiled-coil domain containing 168
chr1_-_151431909 0.00 ENST00000361398.3
ENST00000271715.2
pogo transposable element with ZNF domain
chr2_-_98280383 0.00 ENST00000289228.5
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr20_+_56964169 0.00 ENST00000475243.1
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr9_+_80912059 0.00 ENST00000347159.2
ENST00000376588.3
phosphoserine aminotransferase 1
chr11_-_71823266 0.00 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
anaphase promoting complex subunit 15
chr1_-_8877692 0.00 ENST00000400908.2
arginine-glutamic acid dipeptide (RE) repeats
chr4_-_171012844 0.00 ENST00000502392.1
aminoadipate aminotransferase
chr8_+_1993173 0.00 ENST00000523438.1
myomesin 2
chr2_+_187371440 0.00 ENST00000445547.1
zinc finger CCCH-type containing 15
chr11_+_108535849 0.00 ENST00000526794.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr11_+_33061543 0.00 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
t-complex 11, testis-specific-like 1
chr9_-_5339873 0.00 ENST00000223862.1
ENST00000223858.4
relaxin 1
chr8_+_1993152 0.00 ENST00000262113.4
myomesin 2
chr19_+_11485333 0.00 ENST00000312423.2
SWIM-type zinc finger 7 associated protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.0 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.0 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.0 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)