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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MYBL2

Z-value: 1.49

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Transcription factors associated with MYBL2

Gene Symbol Gene ID Gene Info
MYBL2
ENSG00000101057.11 MYB proto-oncogene like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MYBL2hg19_v2_chr20_+_42295745_42295797-0.592.2e-01Click!

Activity profile of MYBL2 motif

Sorted Z-values of MYBL2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_89300158 0.87 ENST00000502870.1
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr16_-_3285144 0.71 ENST00000431561.3
ENST00000396870.4
ZNF200
zinc finger protein 200
chr2_+_223725723 0.67 ENST00000535678.1
ACSL3
acyl-CoA synthetase long-chain family member 3
chr14_+_65016620 0.64 ENST00000298705.1
PPP1R36
protein phosphatase 1, regulatory subunit 36
chr17_-_58469591 0.62 ENST00000589335.1
USP32
ubiquitin specific peptidase 32
chr9_-_4679419 0.61 ENST00000609131.1
ENST00000607997.1
RP11-6J24.6
RP11-6J24.6
chr14_+_54863682 0.59 ENST00000543789.2
ENST00000442975.2
ENST00000458126.2
ENST00000556102.2
CDKN3
cyclin-dependent kinase inhibitor 3
chr8_-_124665190 0.56 ENST00000325995.7
KLHL38
kelch-like family member 38
chr1_+_92414952 0.56 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
BRDT
bromodomain, testis-specific
chr3_-_165555200 0.55 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr1_-_235098861 0.55 ENST00000458044.1
RP11-443B7.1
RP11-443B7.1
chr8_+_67344710 0.54 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
ADHFE1
alcohol dehydrogenase, iron containing, 1
chrX_-_46759138 0.52 ENST00000377879.3
CXorf31
chromosome X open reading frame 31
chr2_-_17699691 0.51 ENST00000399080.2
RAD51AP2
RAD51 associated protein 2
chr3_+_178865887 0.50 ENST00000477735.1
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr9_-_3469181 0.48 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr1_+_91966384 0.48 ENST00000430031.2
ENST00000234626.6
CDC7
cell division cycle 7
chrX_-_117107680 0.47 ENST00000447671.2
ENST00000262820.3
KLHL13
kelch-like family member 13
chr16_+_19535235 0.46 ENST00000565376.2
ENST00000396208.2
CCP110
centriolar coiled coil protein 110kDa
chr14_+_75536335 0.45 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr1_+_156308245 0.44 ENST00000368253.2
ENST00000470342.1
ENST00000368254.1
TSACC
TSSK6 activating co-chaperone
chr12_-_58329888 0.44 ENST00000546580.1
RP11-620J15.3
RP11-620J15.3
chr3_-_122233723 0.44 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1
karyopherin alpha 1 (importin alpha 5)
chrX_-_107019181 0.43 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22D3
TSC22 domain family, member 3
chr3_-_42003479 0.43 ENST00000420927.1
ULK4
unc-51 like kinase 4
chr12_-_110906027 0.43 ENST00000537466.2
ENST00000550974.1
ENST00000228827.3
GPN3
GPN-loop GTPase 3
chr1_-_152131703 0.42 ENST00000316073.3
RPTN
repetin
chr1_+_85527987 0.42 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr17_+_62503073 0.42 ENST00000580188.1
ENST00000581056.1
CEP95
centrosomal protein 95kDa
chr2_-_25194476 0.42 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr6_-_121655850 0.41 ENST00000422369.1
TBC1D32
TBC1 domain family, member 32
chr10_+_118349920 0.41 ENST00000531984.1
PNLIPRP1
pancreatic lipase-related protein 1
chr14_+_54863667 0.41 ENST00000335183.6
CDKN3
cyclin-dependent kinase inhibitor 3
chrX_+_67718863 0.40 ENST00000374622.2
YIPF6
Yip1 domain family, member 6
chr5_-_142077569 0.40 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1
fibroblast growth factor 1 (acidic)
chr11_+_125757556 0.39 ENST00000526028.1
HYLS1
hydrolethalus syndrome 1
chr20_+_54967663 0.38 ENST00000452950.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr13_-_45048386 0.38 ENST00000472477.1
TSC22D1
TSC22 domain family, member 1
chr7_-_42971759 0.37 ENST00000538645.1
ENST00000445517.1
ENST00000223321.4
PSMA2
proteasome (prosome, macropain) subunit, alpha type, 2
chr14_+_74960423 0.37 ENST00000556816.1
ENST00000298818.8
ENST00000554924.1
ISCA2
iron-sulfur cluster assembly 2
chr1_-_85156216 0.37 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr2_-_38830030 0.37 ENST00000410076.1
HNRNPLL
heterogeneous nuclear ribonucleoprotein L-like
chr1_+_243419306 0.37 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8
serologically defined colon cancer antigen 8
chr13_+_25670268 0.37 ENST00000281589.3
PABPC3
poly(A) binding protein, cytoplasmic 3
chr2_-_211341411 0.36 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
LANCL1
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr10_+_98592009 0.36 ENST00000540664.1
ENST00000371103.3
LCOR
ligand dependent nuclear receptor corepressor
chr20_+_34042962 0.36 ENST00000446710.1
ENST00000420564.1
CEP250
centrosomal protein 250kDa
chr5_-_137475071 0.36 ENST00000265191.2
NME5
NME/NM23 family member 5
chr8_-_25315905 0.36 ENST00000221200.4
KCTD9
potassium channel tetramerization domain containing 9
chr16_-_22012419 0.36 ENST00000537222.2
ENST00000424898.2
ENST00000286143.6
PDZD9
PDZ domain containing 9
chr10_-_27389392 0.35 ENST00000376087.4
ANKRD26
ankyrin repeat domain 26
chr2_+_200775971 0.35 ENST00000319974.5
C2orf69
chromosome 2 open reading frame 69
chr14_-_54955376 0.35 ENST00000553333.1
GMFB
glia maturation factor, beta
chr3_-_172241250 0.35 ENST00000420541.2
ENST00000241261.2
TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
chr10_+_91461337 0.35 ENST00000260753.4
ENST00000416354.1
ENST00000394289.2
ENST00000371728.3
KIF20B
kinesin family member 20B
chr1_+_93646238 0.35 ENST00000448243.1
ENST00000370276.1
CCDC18
coiled-coil domain containing 18
chr7_-_152373216 0.34 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr9_+_91926103 0.34 ENST00000314355.6
CKS2
CDC28 protein kinase regulatory subunit 2
chr16_-_30032610 0.34 ENST00000574405.1
DOC2A
double C2-like domains, alpha
chrX_-_117107542 0.34 ENST00000371878.1
KLHL13
kelch-like family member 13
chr7_+_102715315 0.34 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
ARMC10
armadillo repeat containing 10
chr1_-_171711177 0.34 ENST00000415773.1
ENST00000367740.2
VAMP4
vesicle-associated membrane protein 4
chr2_+_201390843 0.33 ENST00000357799.4
ENST00000409203.3
SGOL2
shugoshin-like 2 (S. pombe)
chr12_-_15114191 0.33 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr17_+_7210898 0.33 ENST00000572815.1
EIF5A
eukaryotic translation initiation factor 5A
chr17_-_38574169 0.33 ENST00000423485.1
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr16_-_3422283 0.33 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr5_+_96077888 0.33 ENST00000509259.1
ENST00000503828.1
CAST
calpastatin
chr2_-_174828892 0.32 ENST00000418194.2
SP3
Sp3 transcription factor
chr3_+_156544057 0.32 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
LEKR1
leucine, glutamate and lysine rich 1
chr1_-_108735440 0.32 ENST00000370041.4
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr4_+_175205038 0.32 ENST00000457424.2
ENST00000514712.1
CEP44
centrosomal protein 44kDa
chrX_-_11129229 0.32 ENST00000608176.1
ENST00000433747.2
ENST00000608576.1
ENST00000608916.1
RP11-120D5.1
RP11-120D5.1
chr1_+_246887349 0.32 ENST00000366510.3
SCCPDH
saccharopine dehydrogenase (putative)
chr9_+_4679555 0.31 ENST00000381858.1
ENST00000381854.3
CDC37L1
cell division cycle 37-like 1
chr11_+_34073757 0.31 ENST00000532820.1
CAPRIN1
cell cycle associated protein 1
chrX_+_129473859 0.31 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr5_+_135383008 0.31 ENST00000508767.1
ENST00000604555.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr2_+_7005959 0.31 ENST00000442639.1
RSAD2
radical S-adenosyl methionine domain containing 2
chr10_+_94352956 0.31 ENST00000260731.3
KIF11
kinesin family member 11
chr11_+_85566422 0.31 ENST00000342404.3
CCDC83
coiled-coil domain containing 83
chr5_+_36606700 0.31 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_-_94417339 0.31 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr2_-_69870747 0.31 ENST00000409068.1
AAK1
AP2 associated kinase 1
chr10_-_99052382 0.31 ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ENST00000466484.1
ENST00000358531.4
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough (NMD candidate)
Rho GTPase activating protein 19
chr19_+_38826477 0.31 ENST00000409410.2
ENST00000215069.4
CATSPERG
catsper channel auxiliary subunit gamma
chr16_+_30418910 0.31 ENST00000566625.1
ZNF771
zinc finger protein 771
chr15_-_31283618 0.30 ENST00000563714.1
MTMR10
myotubularin related protein 10
chr2_+_97454321 0.30 ENST00000540067.1
CNNM4
cyclin M4
chr13_-_52026730 0.30 ENST00000420668.2
INTS6
integrator complex subunit 6
chr14_-_23446003 0.30 ENST00000553911.1
AJUBA
ajuba LIM protein
chr9_-_113018835 0.30 ENST00000374517.5
TXN
thioredoxin
chrX_-_20074895 0.29 ENST00000543767.1
MAP7D2
MAP7 domain containing 2
chr1_-_100598444 0.29 ENST00000535161.1
ENST00000287482.5
SASS6
spindle assembly 6 homolog (C. elegans)
chr19_-_52097613 0.29 ENST00000301439.3
AC018755.1
HCG2008157; Uncharacterized protein; cDNA FLJ30403 fis, clone BRACE2008480
chr4_+_17812525 0.29 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr12_-_6602955 0.29 ENST00000543703.1
MRPL51
mitochondrial ribosomal protein L51
chr7_-_129592471 0.29 ENST00000473814.2
ENST00000490974.1
UBE2H
ubiquitin-conjugating enzyme E2H
chr9_-_36400920 0.29 ENST00000357058.3
ENST00000350199.4
RNF38
ring finger protein 38
chr16_+_50059182 0.29 ENST00000562576.1
CNEP1R1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr4_-_47839966 0.29 ENST00000273857.4
ENST00000505909.1
ENST00000502252.1
CORIN
corin, serine peptidase
chr8_+_6566206 0.28 ENST00000518327.1
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5
chr1_+_211500129 0.28 ENST00000427925.2
ENST00000261464.5
TRAF5
TNF receptor-associated factor 5
chr18_+_61575200 0.28 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chrX_-_48056199 0.28 ENST00000311798.1
ENST00000347757.1
SSX5
synovial sarcoma, X breakpoint 5
chr6_+_64282447 0.28 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr10_+_111765562 0.28 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr2_+_48010221 0.28 ENST00000234420.5
MSH6
mutS homolog 6
chr3_-_183145873 0.28 ENST00000447025.2
ENST00000414362.2
ENST00000328913.3
MCF2L2
MCF.2 cell line derived transforming sequence-like 2
chr9_+_34652164 0.28 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr4_+_24797085 0.28 ENST00000382120.3
SOD3
superoxide dismutase 3, extracellular
chr6_-_110011704 0.28 ENST00000448084.2
AK9
adenylate kinase 9
chr3_-_123680246 0.28 ENST00000488653.2
CCDC14
coiled-coil domain containing 14
chr3_-_172428842 0.28 ENST00000424772.1
NCEH1
neutral cholesterol ester hydrolase 1
chr1_-_98386543 0.27 ENST00000423006.2
ENST00000370192.3
ENST00000306031.5
DPYD
dihydropyrimidine dehydrogenase
chr2_+_216946589 0.27 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169
transmembrane protein 169
chr11_-_94965667 0.27 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr10_-_46167722 0.27 ENST00000374366.3
ENST00000344646.5
ZFAND4
zinc finger, AN1-type domain 4
chr2_+_127413481 0.27 ENST00000259254.4
GYPC
glycophorin C (Gerbich blood group)
chr8_-_103250997 0.27 ENST00000522368.1
RRM2B
ribonucleotide reductase M2 B (TP53 inducible)
chr17_+_62503147 0.27 ENST00000553412.1
CEP95
centrosomal protein 95kDa
chr16_-_66764119 0.27 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr11_+_100862811 0.26 ENST00000303130.2
TMEM133
transmembrane protein 133
chr1_+_91966656 0.26 ENST00000428239.1
ENST00000426137.1
CDC7
cell division cycle 7
chr1_-_115301235 0.26 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr9_-_37904084 0.26 ENST00000377716.2
ENST00000242275.6
SLC25A51
solute carrier family 25, member 51
chr14_-_73360796 0.26 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr17_-_62503015 0.26 ENST00000581806.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr11_+_123301012 0.26 ENST00000533341.1
AP000783.1
Uncharacterized protein
chr3_-_123680047 0.26 ENST00000409697.3
CCDC14
coiled-coil domain containing 14
chr1_-_109825719 0.26 ENST00000369904.3
ENST00000369903.2
ENST00000429031.1
ENST00000418914.2
ENST00000409267.1
PSRC1
proline/serine-rich coiled-coil 1
chr20_-_5485166 0.26 ENST00000589201.1
ENST00000379053.4
LINC00654
long intergenic non-protein coding RNA 654
chr3_+_56591184 0.25 ENST00000422222.1
ENST00000394672.3
ENST00000326595.7
CCDC66
coiled-coil domain containing 66
chr5_-_64858944 0.25 ENST00000508421.1
ENST00000510693.1
ENST00000514814.1
ENST00000515497.1
ENST00000396679.1
CENPK
centromere protein K
chr17_+_34948228 0.25 ENST00000251312.5
ENST00000590554.1
DHRS11
dehydrogenase/reductase (SDR family) member 11
chr6_-_26659913 0.25 ENST00000480036.1
ENST00000415922.2
ZNF322
zinc finger protein 322
chr2_-_27712583 0.25 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr16_-_3285049 0.25 ENST00000575948.1
ZNF200
zinc finger protein 200
chr13_+_98628886 0.25 ENST00000490680.1
ENST00000539640.1
ENST00000403772.3
IPO5
importin 5
chr20_+_54967409 0.25 ENST00000415828.1
ENST00000217109.4
ENST00000428552.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr6_+_96969672 0.25 ENST00000369278.4
UFL1
UFM1-specific ligase 1
chr11_-_130184470 0.25 ENST00000357899.4
ENST00000397753.1
ZBTB44
zinc finger and BTB domain containing 44
chr1_-_68698197 0.25 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr3_-_138048631 0.25 ENST00000484930.1
ENST00000475751.1
NME9
NME/NM23 family member 9
chr2_-_152118352 0.25 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr11_-_28129656 0.24 ENST00000263181.6
KIF18A
kinesin family member 18A
chr13_-_60737898 0.24 ENST00000377908.2
ENST00000400319.1
ENST00000400320.1
ENST00000267215.4
DIAPH3
diaphanous-related formin 3
chr17_+_61678225 0.24 ENST00000258975.6
TACO1
translational activator of mitochondrially encoded cytochrome c oxidase I
chr8_-_94753184 0.24 ENST00000520560.1
RBM12B
RNA binding motif protein 12B
chr15_-_43212836 0.24 ENST00000566931.1
ENST00000564431.1
ENST00000567274.1
TTBK2
tau tubulin kinase 2
chr15_+_49715449 0.24 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr10_-_74385811 0.24 ENST00000603011.1
ENST00000401998.3
ENST00000361114.5
ENST00000604238.1
MICU1
mitochondrial calcium uptake 1
chr2_-_61244550 0.24 ENST00000421319.1
PUS10
pseudouridylate synthase 10
chr7_+_72742178 0.24 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr2_+_109403193 0.24 ENST00000412964.2
ENST00000295124.4
CCDC138
coiled-coil domain containing 138
chr2_+_196522032 0.24 ENST00000418005.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr10_-_60027642 0.24 ENST00000373935.3
IPMK
inositol polyphosphate multikinase
chr15_-_70994612 0.24 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr17_+_46908350 0.24 ENST00000258947.3
ENST00000509507.1
ENST00000448105.2
ENST00000570513.1
ENST00000509415.1
ENST00000513119.1
ENST00000416445.2
ENST00000508679.1
ENST00000505071.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr6_+_45296391 0.24 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr4_-_47916543 0.23 ENST00000507489.1
NFXL1
nuclear transcription factor, X-box binding-like 1
chr7_-_27169801 0.23 ENST00000511914.1
HOXA4
homeobox A4
chr6_-_26033796 0.23 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr1_-_109825751 0.23 ENST00000369907.3
ENST00000438534.2
ENST00000369909.2
ENST00000409138.2
PSRC1
proline/serine-rich coiled-coil 1
chr16_+_19535133 0.23 ENST00000396212.2
ENST00000381396.5
CCP110
centriolar coiled coil protein 110kDa
chr2_-_113522177 0.23 ENST00000541405.1
CKAP2L
cytoskeleton associated protein 2-like
chr22_-_39096925 0.23 ENST00000456626.1
ENST00000412832.1
JOSD1
Josephin domain containing 1
chr11_-_67888881 0.23 ENST00000356135.5
CHKA
choline kinase alpha
chr16_-_20817753 0.23 ENST00000389345.5
ENST00000300005.3
ENST00000357967.4
ENST00000569729.1
ERI2
ERI1 exoribonuclease family member 2
chr19_-_14529847 0.23 ENST00000590239.1
ENST00000590696.1
ENST00000591275.1
ENST00000586993.1
DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr8_+_109455830 0.23 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr12_+_69201923 0.23 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr15_-_59041768 0.23 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM10
ADAM metallopeptidase domain 10
chr17_-_38978847 0.23 ENST00000269576.5
KRT10
keratin 10
chr6_-_110011718 0.23 ENST00000532976.1
AK9
adenylate kinase 9
chr19_+_38826415 0.23 ENST00000410018.1
ENST00000409235.3
CATSPERG
catsper channel auxiliary subunit gamma
chr1_+_52521797 0.23 ENST00000313334.8
BTF3L4
basic transcription factor 3-like 4
chr1_-_160232312 0.22 ENST00000440682.1
DCAF8
DDB1 and CUL4 associated factor 8
chr8_+_73921085 0.22 ENST00000276603.5
ENST00000276602.6
ENST00000518874.1
TERF1
telomeric repeat binding factor (NIMA-interacting) 1
chr17_-_34207295 0.22 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr5_-_49737184 0.22 ENST00000508934.1
ENST00000303221.5
EMB
embigin
chr2_+_127413677 0.22 ENST00000356887.7
GYPC
glycophorin C (Gerbich blood group)
chr12_-_27167233 0.22 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
TM7SF3
transmembrane 7 superfamily member 3
chrX_-_135338503 0.22 ENST00000370663.5
MAP7D3
MAP7 domain containing 3
chr17_-_39580775 0.22 ENST00000225550.3
KRT37
keratin 37
chr15_+_41523335 0.22 ENST00000334660.5
CHP1
calcineurin-like EF-hand protein 1
chr7_+_116654958 0.22 ENST00000449366.1
ST7
suppression of tumorigenicity 7
chr10_-_30637906 0.22 ENST00000417581.1
MTPAP
mitochondrial poly(A) polymerase
chr3_-_45957088 0.22 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr3_-_42003613 0.22 ENST00000414606.1
ULK4
unc-51 like kinase 4
chr4_+_148538517 0.22 ENST00000296582.3
ENST00000508208.1
TMEM184C
transmembrane protein 184C
chr6_-_134639042 0.21 ENST00000461976.2
SGK1
serum/glucocorticoid regulated kinase 1
chr3_-_15643090 0.21 ENST00000451445.2
ENST00000421993.1
HACL1
2-hydroxyacyl-CoA lyase 1
chr14_+_45605127 0.21 ENST00000556036.1
ENST00000267430.5
FANCM
Fanconi anemia, complementation group M
chr2_+_30670127 0.21 ENST00000540623.1
ENST00000476038.1
LCLAT1
lysocardiolipin acyltransferase 1
chr18_+_14748194 0.21 ENST00000358984.4
ANKRD30B
ankyrin repeat domain 30B
chr19_-_53606604 0.21 ENST00000599056.1
ENST00000599247.1
ENST00000355147.5
ENST00000429604.1
ENST00000418871.1
ENST00000599637.1
ZNF160
zinc finger protein 160
chr5_+_112074029 0.21 ENST00000512211.2
APC
adenomatous polyposis coli
chr2_+_190722119 0.21 ENST00000452382.1
PMS1
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
chr10_+_64564469 0.21 ENST00000373783.1
ADO
2-aminoethanethiol (cysteamine) dioxygenase

Network of associatons between targets according to the STRING database.

First level regulatory network of MYBL2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.2 0.6 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.2 0.5 GO:0015993 molecular hydrogen transport(GO:0015993)
0.2 0.7 GO:0032053 ciliary basal body organization(GO:0032053)
0.2 0.3 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 0.5 GO:0061569 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.2 0.2 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.1 0.4 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.4 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.5 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.4 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.4 GO:0060437 lung growth(GO:0060437)
0.1 0.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.3 GO:2000283 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.9 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.2 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.3 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.1 0.3 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.7 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.1 0.5 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.2 GO:0010160 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.5 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 0.3 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.2 GO:2000523 negative regulation of regulatory T cell differentiation(GO:0045590) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0007566 embryo implantation(GO:0007566)
0.0 0.4 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:2000861 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.6 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:1902739 interferon-alpha secretion(GO:0072642) telomerase RNA stabilization(GO:0090669) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.4 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.2 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:1901910 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.1 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.3 GO:0015866 ADP transport(GO:0015866)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.0 GO:0009216 purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0042148 strand invasion(GO:0042148)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.2 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.5 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.7 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.3 GO:0015074 mitotic nuclear envelope reassembly(GO:0007084) DNA integration(GO:0015074)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.3 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.8 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.6 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.5 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.1 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.4 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960) enamel mineralization(GO:0070166)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.4 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.8 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.1 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.4 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.3 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.0 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.3 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 0.4 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.4 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.2 GO:1990423 RZZ complex(GO:1990423)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0019034 viral replication complex(GO:0019034)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.3 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0033265 choline binding(GO:0033265)
0.2 0.5 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.3 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.4 GO:0032143 single thymine insertion binding(GO:0032143)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.5 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.2 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.4 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.2 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.5 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.2 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.7 GO:0000150 recombinase activity(GO:0000150)
0.0 1.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0052847 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0032405 MutLalpha complex binding(GO:0032405)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.0 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.1 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.2 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis