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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFATC2_NFATC3

Z-value: 1.45

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Transcription factors associated with NFATC2_NFATC3

Gene Symbol Gene ID Gene Info
NFATC2
ENSG00000101096.15 nuclear factor of activated T cells 2
NFATC3
ENSG00000072736.14 nuclear factor of activated T cells 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC3hg19_v2_chr16_+_68119764_68119868-0.872.6e-02Click!
NFATC2hg19_v2_chr20_-_50179368_501793920.315.5e-01Click!

Activity profile of NFATC2_NFATC3 motif

Sorted Z-values of NFATC2_NFATC3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_138188351 1.93 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr7_-_41742697 1.83 ENST00000242208.4
INHBA
inhibin, beta A
chr16_-_85969774 1.20 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr14_-_21562671 1.17 ENST00000554923.1
ZNF219
zinc finger protein 219
chr1_+_209941942 1.04 ENST00000487271.1
ENST00000477431.1
TRAF3IP3
TRAF3 interacting protein 3
chr14_-_51863853 1.02 ENST00000556762.1
RP11-255G12.3
RP11-255G12.3
chr15_+_45722727 0.99 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr7_+_22766766 0.93 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr6_+_138188378 0.90 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr20_+_44637526 0.90 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr2_+_162949939 0.83 ENST00000432251.1
AC008063.3
AC008063.3
chr8_+_55466915 0.81 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr3_-_161089289 0.80 ENST00000497137.1
SPTSSB
serine palmitoyltransferase, small subunit B
chr4_-_122148620 0.80 ENST00000509841.1
TNIP3
TNFAIP3 interacting protein 3
chr5_+_140514782 0.77 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr3_-_100565249 0.77 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr3_-_141747950 0.74 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr21_+_35553045 0.73 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr6_-_112081113 0.72 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr1_+_67632083 0.72 ENST00000347310.5
ENST00000371002.1
IL23R
interleukin 23 receptor
chr12_+_113354341 0.68 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr6_+_31105426 0.67 ENST00000547221.1
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr4_-_71532207 0.67 ENST00000543780.1
ENST00000391614.3
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr14_+_103589789 0.63 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr8_+_55467072 0.62 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr11_-_9482010 0.62 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr2_-_228244013 0.62 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr5_+_159895275 0.62 ENST00000517927.1
MIR146A
microRNA 146a
chr13_-_30160925 0.59 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr17_-_39093672 0.59 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr17_+_27047570 0.56 ENST00000472628.1
ENST00000578181.1
RPL23A
ribosomal protein L23a
chr14_+_91709103 0.55 ENST00000553725.1
CTD-2547L24.3
HCG1816139; Uncharacterized protein
chr6_-_133055815 0.55 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr6_+_31916733 0.54 ENST00000483004.1
CFB
complement factor B
chr11_-_126174186 0.52 ENST00000524964.1
RP11-712L6.5
Uncharacterized protein
chr8_-_23712312 0.52 ENST00000290271.2
STC1
stanniocalcin 1
chr6_-_133055896 0.51 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr11_-_69867159 0.51 ENST00000528507.1
RP11-626H12.2
RP11-626H12.2
chr11_-_119293872 0.49 ENST00000524970.1
THY1
Thy-1 cell surface antigen
chr12_-_57037284 0.47 ENST00000551570.1
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr3_-_114035026 0.47 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr4_+_39408470 0.46 ENST00000257408.4
KLB
klotho beta
chr7_+_28452130 0.46 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr7_+_66800928 0.45 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr17_+_4853442 0.45 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr1_-_173020056 0.44 ENST00000239468.2
ENST00000404377.3
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chrX_-_133792480 0.44 ENST00000359237.4
PLAC1
placenta-specific 1
chr1_+_81106951 0.43 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr6_+_106546808 0.42 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr14_-_92413727 0.42 ENST00000267620.10
FBLN5
fibulin 5
chr14_-_77889860 0.41 ENST00000555603.1
NOXRED1
NADP-dependent oxidoreductase domain containing 1
chr3_+_99357319 0.41 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1
collagen, type VIII, alpha 1
chr2_+_66918558 0.40 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr14_+_75988851 0.40 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr16_-_3306587 0.40 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
MEFV
Mediterranean fever
chr14_-_76447336 0.39 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr17_+_27046988 0.39 ENST00000496182.1
RPL23A
ribosomal protein L23a
chr17_-_61045902 0.39 ENST00000581596.1
RP11-180P8.3
RP11-180P8.3
chr6_+_106534192 0.38 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr18_-_25739260 0.38 ENST00000413878.1
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr17_-_15522826 0.38 ENST00000395906.3
CDRT1
CMT1A duplicated region transcript 1
chr17_+_18647326 0.38 ENST00000395667.1
ENST00000395665.4
ENST00000308799.4
ENST00000301938.4
FBXW10
F-box and WD repeat domain containing 10
chr17_-_7120498 0.38 ENST00000485100.1
DLG4
discs, large homolog 4 (Drosophila)
chr17_+_27047244 0.37 ENST00000394938.4
ENST00000394935.3
ENST00000355731.4
RPL23A
ribosomal protein L23a
chr12_-_49582978 0.37 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chrX_+_152683780 0.37 ENST00000338647.5
ZFP92
ZFP92 zinc finger protein
chr1_-_204135450 0.36 ENST00000272190.8
ENST00000367195.2
REN
renin
chr17_+_45331184 0.35 ENST00000559488.1
ENST00000571680.1
ENST00000435993.2
ITGB3
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
chr12_-_7244469 0.35 ENST00000538050.1
ENST00000536053.2
C1R
complement component 1, r subcomponent
chr8_-_57123815 0.35 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr15_-_40401062 0.34 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF
Bcl2 modifying factor
chr10_+_30723105 0.34 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr10_+_30723045 0.33 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr18_-_3247084 0.32 ENST00000609924.1
RP13-270P17.3
RP13-270P17.3
chr5_+_140207536 0.32 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr22_+_38203898 0.32 ENST00000323205.6
ENST00000248924.6
ENST00000445195.1
GCAT
glycine C-acetyltransferase
chr13_-_81801115 0.31 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chr11_+_18417948 0.31 ENST00000542179.1
LDHA
lactate dehydrogenase A
chr17_+_16120512 0.30 ENST00000581006.1
ENST00000584797.1
ENST00000498772.2
ENST00000225609.5
ENST00000395844.4
ENST00000477745.1
PIGL
phosphatidylinositol glycan anchor biosynthesis, class L
chrX_+_133941218 0.30 ENST00000370784.4
ENST00000370785.3
FAM122C
family with sequence similarity 122C
chr12_+_49961990 0.30 ENST00000551063.1
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr14_+_24837226 0.30 ENST00000554050.1
ENST00000554903.1
ENST00000554779.1
ENST00000250373.4
ENST00000553708.1
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr12_+_54393880 0.29 ENST00000303450.4
HOXC9
homeobox C9
chrY_-_15591485 0.29 ENST00000382896.4
ENST00000537580.1
ENST00000540140.1
ENST00000545955.1
ENST00000538878.1
UTY
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr11_+_102188272 0.29 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr14_-_92413353 0.28 ENST00000556154.1
FBLN5
fibulin 5
chr8_+_128748466 0.28 ENST00000524013.1
ENST00000520751.1
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr2_+_172543919 0.28 ENST00000452242.1
ENST00000340296.4
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr7_-_139756791 0.28 ENST00000489809.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr5_+_66124590 0.28 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr3_-_71353892 0.28 ENST00000484350.1
FOXP1
forkhead box P1
chr2_+_162272605 0.28 ENST00000389554.3
TBR1
T-box, brain, 1
chr17_-_7120525 0.27 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
DLG4
discs, large homolog 4 (Drosophila)
chr7_-_150754935 0.27 ENST00000297518.4
CDK5
cyclin-dependent kinase 5
chr12_-_49582593 0.26 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr14_+_65170820 0.26 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr9_-_73483926 0.26 ENST00000396283.1
ENST00000361823.5
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chrX_+_84498989 0.26 ENST00000395402.1
ZNF711
zinc finger protein 711
chr22_-_30642728 0.26 ENST00000403987.3
LIF
leukemia inhibitory factor
chrX_+_9431324 0.26 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr17_+_67759813 0.26 ENST00000587241.1
AC003051.1
AC003051.1
chrX_-_100662881 0.26 ENST00000218516.3
GLA
galactosidase, alpha
chr14_-_88200641 0.26 ENST00000556168.1
RP11-1152H15.1
RP11-1152H15.1
chr14_-_24615805 0.26 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr5_-_115910630 0.25 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr5_-_150466692 0.25 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr12_-_96793142 0.25 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17
chr5_-_111093759 0.25 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr4_+_22999152 0.25 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chrX_-_139866723 0.25 ENST00000370532.2
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr6_+_12290586 0.25 ENST00000379375.5
EDN1
endothelin 1
chr11_+_101983176 0.25 ENST00000524575.1
YAP1
Yes-associated protein 1
chr17_-_61776522 0.25 ENST00000582055.1
LIMD2
LIM domain containing 2
chr15_+_93443419 0.25 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr12_-_92536433 0.25 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr6_+_32407619 0.24 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr12_-_49582837 0.24 ENST00000547939.1
ENST00000546918.1
ENST00000552924.1
TUBA1A
tubulin, alpha 1a
chr11_+_102188224 0.24 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr5_-_147162263 0.24 ENST00000333010.6
ENST00000265272.5
JAKMIP2
janus kinase and microtubule interacting protein 2
chr11_-_102714534 0.24 ENST00000299855.5
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr14_-_89878369 0.24 ENST00000553840.1
ENST00000556916.1
FOXN3
forkhead box N3
chr11_-_85397167 0.24 ENST00000316398.3
CCDC89
coiled-coil domain containing 89
chr5_+_167718604 0.24 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr18_-_33047039 0.23 ENST00000591141.1
ENST00000586741.1
RP11-322E11.5
RP11-322E11.5
chr9_-_136283156 0.23 ENST00000371942.3
REXO4
REX4, RNA exonuclease 4 homolog (S. cerevisiae)
chr1_+_149239529 0.23 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr5_+_140220769 0.23 ENST00000531613.1
ENST00000378123.3
PCDHA8
protocadherin alpha 8
chr2_-_113594279 0.23 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr11_+_18417813 0.23 ENST00000540430.1
ENST00000379412.5
LDHA
lactate dehydrogenase A
chr22_-_19466643 0.23 ENST00000474226.1
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr22_-_39640756 0.23 ENST00000331163.6
PDGFB
platelet-derived growth factor beta polypeptide
chr2_-_165424973 0.23 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr11_-_46142948 0.23 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr7_+_20686946 0.22 ENST00000443026.2
ENST00000406935.1
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr11_-_2924970 0.22 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr1_-_246670519 0.22 ENST00000388985.4
ENST00000490107.1
SMYD3
SET and MYND domain containing 3
chr12_-_89918982 0.22 ENST00000549504.1
POC1B
POC1 centriolar protein B
chr1_+_186265399 0.22 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr6_-_134495992 0.22 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1
serum/glucocorticoid regulated kinase 1
chr14_+_65171099 0.22 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chrX_-_43832711 0.22 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr6_-_26235206 0.22 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr3_-_39195037 0.22 ENST00000273153.5
CSRNP1
cysteine-serine-rich nuclear protein 1
chr22_-_50699701 0.22 ENST00000395780.1
MAPK12
mitogen-activated protein kinase 12
chr5_-_146461027 0.21 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr6_+_116832789 0.21 ENST00000368599.3
FAM26E
family with sequence similarity 26, member E
chr7_-_121944491 0.21 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr5_-_64777733 0.21 ENST00000381055.3
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr11_-_111749767 0.21 ENST00000542429.1
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr22_-_19466683 0.21 ENST00000399523.1
ENST00000421968.2
ENST00000447868.1
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr13_-_33780133 0.21 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr3_-_71632894 0.21 ENST00000493089.1
FOXP1
forkhead box P1
chr17_-_46657473 0.21 ENST00000332503.5
HOXB4
homeobox B4
chr11_+_34663913 0.21 ENST00000532302.1
EHF
ets homologous factor
chr1_+_79115503 0.21 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr17_+_38334501 0.20 ENST00000541245.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr18_-_3845293 0.20 ENST00000400145.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr12_+_6554021 0.20 ENST00000266557.3
CD27
CD27 molecule
chr3_-_134092561 0.20 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2
angiomotin like 2
chr17_+_7387677 0.20 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr8_-_73793975 0.20 ENST00000523881.1
RP11-1145L24.1
RP11-1145L24.1
chr2_-_191885686 0.20 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr1_+_38022513 0.20 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr14_+_78227105 0.20 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178
chromosome 14 open reading frame 178
chr10_-_50323543 0.20 ENST00000332853.4
ENST00000298454.3
VSTM4
V-set and transmembrane domain containing 4
chr15_-_65503801 0.20 ENST00000261883.4
CILP
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr2_+_149974684 0.20 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr11_+_34654011 0.20 ENST00000531794.1
EHF
ets homologous factor
chr19_+_1041187 0.20 ENST00000531467.1
ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr8_-_74495065 0.19 ENST00000523533.1
STAU2
staufen double-stranded RNA binding protein 2
chr16_+_66400533 0.19 ENST00000341529.3
CDH5
cadherin 5, type 2 (vascular endothelium)
chr12_-_2944184 0.19 ENST00000337508.4
NRIP2
nuclear receptor interacting protein 2
chr18_+_3451584 0.19 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr6_+_106535455 0.19 ENST00000424894.1
PRDM1
PR domain containing 1, with ZNF domain
chr5_-_108063949 0.19 ENST00000606054.1
LINC01023
long intergenic non-protein coding RNA 1023
chr2_-_127963343 0.19 ENST00000335247.7
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr10_-_75118611 0.19 ENST00000355577.3
ENST00000394865.1
ENST00000310715.3
ENST00000401621.2
TTC18
tetratricopeptide repeat domain 18
chr19_+_45690646 0.19 ENST00000591569.1
AC006126.3
Uncharacterized protein
chr8_-_74884341 0.19 ENST00000284811.8
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr11_-_57089774 0.19 ENST00000527207.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr5_+_38845960 0.19 ENST00000502536.1
OSMR
oncostatin M receptor
chr10_+_118305435 0.19 ENST00000369221.2
PNLIP
pancreatic lipase
chr1_+_150254936 0.19 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr11_-_119293903 0.19 ENST00000580275.1
THY1
Thy-1 cell surface antigen
chr16_+_30211181 0.18 ENST00000395138.2
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr6_+_152011628 0.18 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr5_+_38846101 0.18 ENST00000274276.3
OSMR
oncostatin M receptor
chr20_+_33464238 0.18 ENST00000360596.2
ACSS2
acyl-CoA synthetase short-chain family member 2
chr6_+_26183958 0.18 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr17_+_79953310 0.18 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr7_-_111424462 0.18 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr12_+_46777450 0.18 ENST00000551503.1
RP11-96H19.1
RP11-96H19.1
chr10_+_90521163 0.18 ENST00000404459.1
LIPN
lipase, family member N
chrX_+_135730297 0.18 ENST00000370629.2
CD40LG
CD40 ligand
chrX_+_135730373 0.18 ENST00000370628.2
CD40LG
CD40 ligand
chr2_-_163100045 0.18 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr17_-_56492989 0.18 ENST00000583753.1
RNF43
ring finger protein 43
chr12_-_7245018 0.18 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr11_+_64004888 0.17 ENST00000541681.1
VEGFB
vascular endothelial growth factor B
chr18_-_3845321 0.17 ENST00000539435.1
ENST00000400147.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC2_NFATC3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291) negative regulation of CD40 signaling pathway(GO:2000349)
0.6 1.8 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 1.0 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 0.9 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.2 0.7 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.7 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 0.4 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.1 0.8 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.4 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.4 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.4 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.2 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.1 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.6 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.3 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.5 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 0.4 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.1 0.1 GO:1900212 mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.1 0.3 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.6 GO:0035932 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.1 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.9 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.7 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 0.2 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.1 0.4 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 1.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.6 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.2 GO:1900241 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.2 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.2 GO:0048749 compound eye development(GO:0048749)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.1 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.1 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.2 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.5 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.4 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.1 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1 0.3 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.2 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.2 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.4 GO:2000809 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:1903660 cellular response to mercury ion(GO:0071288) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.3 GO:0021764 amygdala development(GO:0021764)
0.0 0.4 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.5 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.0 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.7 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.5 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0038194 thyroid-stimulating hormone signaling pathway(GO:0038194)
0.0 0.2 GO:0031620 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.4 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.1 GO:0045416 very-low-density lipoprotein particle remodeling(GO:0034372) positive regulation of interleukin-8 biosynthetic process(GO:0045416) regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.4 GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.0 0.1 GO:0061485 memory T cell proliferation(GO:0061485)
0.0 0.3 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 1.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0019541 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.6 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0016598 protein arginylation(GO:0016598)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.2 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:0060581 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101) RNA repair(GO:0042245)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.3 GO:0051001 glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477) negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.6 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0052042 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.0 0.2 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.0 0.1 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0051510 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.1 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.2 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 1.0 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.2 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 0.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.2 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.0 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.0 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.0 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.8 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.6 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.0 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 0.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 0.4 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.7 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.5 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.7 GO:0071953 elastic fiber(GO:0071953)
0.1 0.2 GO:0045160 myosin I complex(GO:0045160)
0.1 0.6 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 1.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.4 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.0 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.0 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0034711 inhibin binding(GO:0034711)
0.2 1.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 0.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 2.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.7 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 1.3 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.4 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.2 GO:0031705 bombesin receptor binding(GO:0031705)
0.1 0.7 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.7 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.4 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.5 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.3 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.2 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.5 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0004057 arginyltransferase activity(GO:0004057)
0.0 0.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.6 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 1.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.0 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.0 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.0 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.0 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.0 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 PID CD40 PATHWAY CD40/CD40L signaling
0.1 0.9 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 2.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters