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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFATC4

Z-value: 0.88

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Transcription factors associated with NFATC4

Gene Symbol Gene ID Gene Info
NFATC4
ENSG00000100968.9 nuclear factor of activated T cells 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC4hg19_v2_chr14_+_24837226_24837547-0.749.3e-02Click!

Activity profile of NFATC4 motif

Sorted Z-values of NFATC4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_86116396 0.51 ENST00000455121.3
AC105053.4
AC105053.4
chr22_-_39548443 0.41 ENST00000401405.3
CBX7
chromobox homolog 7
chr12_-_58329888 0.39 ENST00000546580.1
RP11-620J15.3
RP11-620J15.3
chr11_-_126174186 0.37 ENST00000524964.1
RP11-712L6.5
Uncharacterized protein
chr14_-_51135005 0.37 ENST00000556735.1
SAV1
salvador homolog 1 (Drosophila)
chrX_+_100224676 0.26 ENST00000450049.2
ARL13A
ADP-ribosylation factor-like 13A
chr1_-_100643765 0.25 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39
leucine rich repeat containing 39
chr2_+_201994208 0.25 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr4_+_26322409 0.25 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr6_-_53530474 0.25 ENST00000370905.3
KLHL31
kelch-like family member 31
chr2_-_165697717 0.25 ENST00000439313.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr4_+_175205038 0.24 ENST00000457424.2
ENST00000514712.1
CEP44
centrosomal protein 44kDa
chr14_+_32546145 0.24 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr16_-_18937072 0.24 ENST00000569122.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr8_-_25281747 0.24 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr14_+_75536335 0.23 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr3_-_49837254 0.23 ENST00000412678.2
ENST00000343366.4
ENST00000487256.1
CDHR4
cadherin-related family member 4
chr11_-_62457371 0.21 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr14_+_96858433 0.21 ENST00000267584.4
AK7
adenylate kinase 7
chr14_+_21156915 0.21 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr14_+_32546274 0.21 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr7_+_23210760 0.21 ENST00000366347.4
AC005082.1
Uncharacterized protein
chr19_+_10959043 0.20 ENST00000397820.4
C19orf38
chromosome 19 open reading frame 38
chr12_+_51318513 0.20 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr8_+_101349823 0.20 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr14_-_54955376 0.20 ENST00000553333.1
GMFB
glia maturation factor, beta
chr1_+_212782012 0.19 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr18_-_3247084 0.19 ENST00000609924.1
RP13-270P17.3
RP13-270P17.3
chr5_+_63461642 0.19 ENST00000296615.6
ENST00000381081.2
ENST00000389100.4
RNF180
ring finger protein 180
chr2_+_191208196 0.19 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr17_-_34207295 0.18 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chrX_-_48827976 0.18 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr11_+_100862811 0.18 ENST00000303130.2
TMEM133
transmembrane protein 133
chr1_+_78470530 0.18 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr10_-_116444371 0.18 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr12_-_47219733 0.18 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4
solute carrier family 38, member 4
chr15_-_77712477 0.17 ENST00000560626.2
PEAK1
pseudopodium-enriched atypical kinase 1
chr2_+_201994042 0.17 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr7_-_152373216 0.17 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr11_+_62475130 0.17 ENST00000294117.5
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr17_-_58603482 0.17 ENST00000585368.1
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr14_+_58754751 0.17 ENST00000598233.1
AL132989.1
AL132989.1
chr2_+_98703595 0.17 ENST00000435344.1
VWA3B
von Willebrand factor A domain containing 3B
chr1_-_113161730 0.17 ENST00000544629.1
ENST00000543570.1
ENST00000360743.4
ENST00000490067.1
ENST00000343210.7
ENST00000369666.1
ST7L
suppression of tumorigenicity 7 like
chr10_-_16563870 0.16 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr17_-_58499766 0.16 ENST00000588898.1
USP32
ubiquitin specific peptidase 32
chr5_-_43412418 0.16 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chr11_-_124806297 0.16 ENST00000298251.4
HEPACAM
hepatic and glial cell adhesion molecule
chr4_+_175205100 0.16 ENST00000515299.1
CEP44
centrosomal protein 44kDa
chr2_+_191208601 0.16 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr17_+_67590125 0.16 ENST00000591334.1
AC003051.1
AC003051.1
chr3_+_98451532 0.15 ENST00000486334.2
ENST00000394162.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr6_-_146057144 0.15 ENST00000367519.3
EPM2A
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr15_+_84841242 0.15 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr2_-_207629997 0.15 ENST00000454776.2
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr17_-_1613663 0.15 ENST00000330676.6
TLCD2
TLC domain containing 2
chr2_+_98703695 0.15 ENST00000451075.2
VWA3B
von Willebrand factor A domain containing 3B
chr1_-_151826173 0.15 ENST00000368817.5
THEM5
thioesterase superfamily member 5
chr11_-_46142948 0.15 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr17_+_44701402 0.15 ENST00000575068.1
NSF
N-ethylmaleimide-sensitive factor
chr1_-_145470383 0.15 ENST00000369314.1
ENST00000369313.3
POLR3GL
polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
chr9_-_13165457 0.14 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr13_+_102104980 0.14 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr8_+_28747884 0.14 ENST00000287701.10
ENST00000444075.1
ENST00000403668.2
ENST00000519662.1
ENST00000558662.1
ENST00000523613.1
ENST00000560599.1
ENST00000397358.3
HMBOX1
homeobox containing 1
chrX_+_22056165 0.14 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr12_-_49075941 0.14 ENST00000553086.1
ENST00000548304.1
KANSL2
KAT8 regulatory NSL complex subunit 2
chr11_-_5537920 0.13 ENST00000380184.1
UBQLNL
ubiquilin-like
chr6_-_26235206 0.13 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr11_-_61735029 0.13 ENST00000526640.1
FTH1
ferritin, heavy polypeptide 1
chr1_+_99127225 0.13 ENST00000370189.5
ENST00000529992.1
SNX7
sorting nexin 7
chr8_+_70404996 0.13 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr1_+_99127265 0.13 ENST00000306121.3
SNX7
sorting nexin 7
chr2_+_191208791 0.13 ENST00000423767.1
ENST00000451089.1
INPP1
inositol polyphosphate-1-phosphatase
chr3_+_178865887 0.13 ENST00000477735.1
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr2_+_191208656 0.13 ENST00000458647.1
INPP1
inositol polyphosphate-1-phosphatase
chr7_-_105319536 0.13 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr14_-_30396948 0.13 ENST00000331968.5
PRKD1
protein kinase D1
chr22_-_29107919 0.13 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr3_+_154797781 0.13 ENST00000382989.3
MME
membrane metallo-endopeptidase
chr3_+_138340067 0.13 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr17_+_6900201 0.12 ENST00000480801.1
ALOX12
arachidonate 12-lipoxygenase
chr11_-_46142615 0.12 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr1_-_113162040 0.12 ENST00000358039.4
ENST00000369668.2
ST7L
suppression of tumorigenicity 7 like
chr5_+_72112418 0.12 ENST00000454282.1
TNPO1
transportin 1
chr12_-_95467267 0.12 ENST00000330677.7
NR2C1
nuclear receptor subfamily 2, group C, member 1
chr5_+_15500280 0.12 ENST00000504595.1
FBXL7
F-box and leucine-rich repeat protein 7
chr17_+_65375082 0.12 ENST00000584471.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chrX_+_23928500 0.12 ENST00000435707.1
CXorf58
chromosome X open reading frame 58
chr20_+_33464238 0.12 ENST00000360596.2
ACSS2
acyl-CoA synthetase short-chain family member 2
chr11_-_46113756 0.12 ENST00000531959.1
PHF21A
PHD finger protein 21A
chr12_+_56511943 0.12 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
ZC3H10
ESYT1
zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr21_+_17791838 0.12 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr1_-_234667504 0.12 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr18_+_3451584 0.12 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr3_-_93747425 0.12 ENST00000315099.2
STX19
syntaxin 19
chr17_+_40996590 0.12 ENST00000253799.3
ENST00000452774.2
AOC2
amine oxidase, copper containing 2 (retina-specific)
chr14_+_54863682 0.12 ENST00000543789.2
ENST00000442975.2
ENST00000458126.2
ENST00000556102.2
CDKN3
cyclin-dependent kinase inhibitor 3
chr6_-_131384412 0.12 ENST00000445890.2
ENST00000368128.2
ENST00000337057.3
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_-_155881156 0.12 ENST00000539040.1
ENST00000368323.3
RIT1
Ras-like without CAAX 1
chr10_+_25305524 0.12 ENST00000524413.1
ENST00000376356.4
THNSL1
threonine synthase-like 1 (S. cerevisiae)
chr1_-_161337662 0.12 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr15_-_90437195 0.12 ENST00000560940.1
ENST00000558011.1
AP3S2
adaptor-related protein complex 3, sigma 2 subunit
chr12_+_41086215 0.11 ENST00000547702.1
ENST00000551424.1
CNTN1
contactin 1
chr17_+_5389605 0.11 ENST00000576988.1
ENST00000576570.1
ENST00000573759.1
MIS12
MIS12 kinetochore complex component
chr19_+_37095719 0.11 ENST00000423582.1
ZNF382
zinc finger protein 382
chr1_-_68698197 0.11 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr12_-_54653313 0.11 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr5_+_158690089 0.11 ENST00000296786.6
UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr7_-_64023441 0.11 ENST00000309683.6
ZNF680
zinc finger protein 680
chr5_+_102090974 0.11 ENST00000512073.1
PAM
peptidylglycine alpha-amidating monooxygenase
chrX_+_129473916 0.11 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr2_+_204193101 0.11 ENST00000430418.1
ENST00000424558.1
ENST00000261016.6
ABI2
abl-interactor 2
chr2_+_98703643 0.11 ENST00000477737.1
VWA3B
von Willebrand factor A domain containing 3B
chr6_-_131384373 0.11 ENST00000392427.3
ENST00000525271.1
ENST00000527411.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr3_-_197024394 0.11 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr3_+_160559931 0.11 ENST00000464260.1
ENST00000295839.9
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chrX_+_100663243 0.11 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr2_-_97405775 0.11 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L
lectin, mannose-binding 2-like
chr1_-_150780757 0.11 ENST00000271651.3
CTSK
cathepsin K
chr3_-_46068969 0.11 ENST00000542109.1
ENST00000395946.2
XCR1
chemokine (C motif) receptor 1
chr5_+_154238149 0.11 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr4_-_48683188 0.11 ENST00000505759.1
FRYL
FRY-like
chr4_+_26322185 0.11 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr21_+_17791648 0.11 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr2_-_175113301 0.11 ENST00000344357.5
ENST00000284719.3
OLA1
Obg-like ATPase 1
chr17_-_44657017 0.11 ENST00000573185.1
ENST00000570550.1
ENST00000445552.2
ENST00000336125.5
ENST00000329240.4
ENST00000337845.7
ARL17A
ADP-ribosylation factor-like 17A
chr22_-_39548511 0.11 ENST00000434260.1
CBX7
chromobox homolog 7
chr14_+_81421921 0.10 ENST00000554263.1
ENST00000554435.1
TSHR
thyroid stimulating hormone receptor
chr12_+_64798826 0.10 ENST00000540203.1
XPOT
exportin, tRNA
chr12_-_39734783 0.10 ENST00000552961.1
KIF21A
kinesin family member 21A
chr14_+_54863667 0.10 ENST00000335183.6
CDKN3
cyclin-dependent kinase inhibitor 3
chr18_-_64271316 0.10 ENST00000540086.1
ENST00000580157.1
CDH19
cadherin 19, type 2
chr2_-_207630033 0.10 ENST00000449792.1
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr4_+_175204818 0.10 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr14_-_61748550 0.10 ENST00000555868.1
TMEM30B
transmembrane protein 30B
chr6_-_132834184 0.10 ENST00000367941.2
ENST00000367937.4
STX7
syntaxin 7
chr11_-_46142505 0.10 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr6_-_159065741 0.10 ENST00000367085.3
ENST00000367089.3
DYNLT1
dynein, light chain, Tctex-type 1
chr12_+_21654714 0.10 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr10_-_7453445 0.10 ENST00000379713.3
ENST00000397167.1
ENST00000397160.3
SFMBT2
Scm-like with four mbt domains 2
chr1_-_8075693 0.10 ENST00000467067.1
ERRFI1
ERBB receptor feedback inhibitor 1
chr2_+_29353520 0.10 ENST00000438819.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr2_-_55277692 0.10 ENST00000394611.2
RTN4
reticulon 4
chr1_+_206317591 0.10 ENST00000432969.2
CTSE
cathepsin E
chr11_-_47600320 0.10 ENST00000525720.1
ENST00000531067.1
ENST00000533290.1
ENST00000529499.1
ENST00000529946.1
ENST00000526005.1
ENST00000395288.2
ENST00000534239.1
KBTBD4
kelch repeat and BTB (POZ) domain containing 4
chr17_+_52978185 0.10 ENST00000572405.1
ENST00000572158.1
ENST00000540336.1
ENST00000572298.1
ENST00000536554.1
ENST00000575333.1
ENST00000570499.1
ENST00000572576.1
TOM1L1
target of myb1 (chicken)-like 1
chr2_-_191115229 0.10 ENST00000409820.2
ENST00000410045.1
HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr9_+_26956371 0.10 ENST00000380062.5
ENST00000518614.1
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr6_+_122720681 0.10 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr5_-_42812143 0.10 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr7_-_107204337 0.10 ENST00000605888.1
ENST00000347053.3
COG5
component of oligomeric golgi complex 5
chr3_+_98451093 0.10 ENST00000483910.1
ENST00000460774.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr18_+_5238549 0.10 ENST00000580684.1
LINC00667
long intergenic non-protein coding RNA 667
chr12_-_56105880 0.10 ENST00000557257.1
ITGA7
integrin, alpha 7
chr3_+_142342228 0.10 ENST00000337777.3
PLS1
plastin 1
chr12_-_76461249 0.10 ENST00000551524.1
NAP1L1
nucleosome assembly protein 1-like 1
chr10_+_114710516 0.09 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr15_-_77712429 0.09 ENST00000564328.1
ENST00000558305.1
PEAK1
pseudopodium-enriched atypical kinase 1
chr11_+_1942580 0.09 ENST00000381558.1
TNNT3
troponin T type 3 (skeletal, fast)
chr12_+_3600356 0.09 ENST00000382622.3
PRMT8
protein arginine methyltransferase 8
chr12_-_21910775 0.09 ENST00000539782.1
LDHB
lactate dehydrogenase B
chr4_+_89300158 0.09 ENST00000502870.1
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr20_+_35201993 0.09 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr3_+_69812877 0.09 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr1_+_65613513 0.09 ENST00000395334.2
AK4
adenylate kinase 4
chr11_-_47600549 0.09 ENST00000430070.2
KBTBD4
kelch repeat and BTB (POZ) domain containing 4
chr3_+_63953415 0.09 ENST00000484332.1
ATXN7
ataxin 7
chr7_-_99679324 0.09 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
ZNF3
zinc finger protein 3
chr6_-_56716686 0.09 ENST00000520645.1
DST
dystonin
chr11_+_114271367 0.09 ENST00000544582.1
ENST00000545678.1
RBM7
RNA binding motif protein 7
chr15_-_72563585 0.09 ENST00000287196.9
ENST00000260376.7
PARP6
poly (ADP-ribose) polymerase family, member 6
chr1_-_52521831 0.09 ENST00000371626.4
TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr4_-_175204765 0.09 ENST00000513696.1
ENST00000503293.1
FBXO8
F-box protein 8
chr4_-_176733897 0.09 ENST00000393658.2
GPM6A
glycoprotein M6A
chr1_+_155178518 0.09 ENST00000316721.4
MTX1
metaxin 1
chrX_-_102943022 0.09 ENST00000433176.2
MORF4L2
mortality factor 4 like 2
chr12_-_47226152 0.09 ENST00000546940.1
SLC38A4
solute carrier family 38, member 4
chr4_-_52883786 0.09 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr3_-_42642560 0.09 ENST00000417572.1
SEC22C
SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
chrX_-_84634708 0.09 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chr6_-_31510181 0.09 ENST00000458640.1
ENST00000396172.1
ENST00000417556.2
DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr5_+_68462944 0.09 ENST00000506572.1
CCNB1
cyclin B1
chrX_+_70503526 0.09 ENST00000413858.1
ENST00000450092.1
NONO
non-POU domain containing, octamer-binding
chr10_-_62704005 0.08 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr7_-_92157747 0.08 ENST00000428214.1
ENST00000438045.1
PEX1
peroxisomal biogenesis factor 1
chr12_+_10460417 0.08 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
KLRD1
killer cell lectin-like receptor subfamily D, member 1
chr7_-_92777606 0.08 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr19_+_52772832 0.08 ENST00000593703.1
ENST00000601711.1
ENST00000599581.1
ZNF766
zinc finger protein 766
chr8_+_94767109 0.08 ENST00000409623.3
ENST00000453906.1
ENST00000521517.1
TMEM67
transmembrane protein 67
chr3_+_98451275 0.08 ENST00000265261.6
ENST00000497008.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr16_-_85969774 0.08 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr6_-_131384347 0.08 ENST00000530481.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_-_155880672 0.08 ENST00000609492.1
ENST00000368322.3
RIT1
Ras-like without CAAX 1
chr1_+_40627038 0.08 ENST00000372771.4
RLF
rearranged L-myc fusion
chr1_-_150207017 0.08 ENST00000369119.3
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr2_+_223916862 0.08 ENST00000604125.1
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr3_-_149375783 0.08 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr11_+_65190245 0.08 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr2_+_27301435 0.08 ENST00000380320.4
EMILIN1
elastin microfibril interfacer 1
chr1_-_151299842 0.08 ENST00000438243.2
ENST00000489223.2
ENST00000368873.1
ENST00000430800.1
ENST00000368872.1
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0046883 hormone secretion(GO:0046879) regulation of hormone secretion(GO:0046883)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.2 GO:1990637 response to prolactin(GO:1990637)
0.1 0.4 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.0 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0097018 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.4 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:2001302 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.1 GO:2000775 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0038194 thyroid-stimulating hormone signaling pathway(GO:0038194)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.2 GO:1901727 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0019413 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.0 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.4 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.0 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.1 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.0 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.0 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.0 GO:0070858 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) negative regulation of bile acid biosynthetic process(GO:0070858) acinar cell differentiation(GO:0090425) negative regulation of bile acid metabolic process(GO:1904252) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.3 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290) formaldehyde metabolic process(GO:0046292)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341) male mating behavior(GO:0060179)
0.0 0.1 GO:1903764 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.0 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.3 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.0 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0031403 lithium ion binding(GO:0031403)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.0 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.0 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)