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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFE2L1

Z-value: 1.30

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Transcription factors associated with NFE2L1

Gene Symbol Gene ID Gene Info
NFE2L1
ENSG00000082641.11 nuclear factor, erythroid 2 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L1hg19_v2_chr17_+_46131912_46131952-0.928.6e-03Click!

Activity profile of NFE2L1 motif

Sorted Z-values of NFE2L1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_74606223 0.87 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr2_+_113735575 0.86 ENST00000376489.2
ENST00000259205.4
IL36G
interleukin 36, gamma
chr2_-_25451065 0.80 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr6_+_13272904 0.67 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr1_+_81106951 0.67 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr16_+_31044413 0.61 ENST00000394998.1
STX4
syntaxin 4
chr19_-_42192189 0.60 ENST00000401731.1
ENST00000338196.4
ENST00000006724.3
CEACAM7
carcinoembryonic antigen-related cell adhesion molecule 7
chr15_-_34502197 0.54 ENST00000557877.1
KATNBL1
katanin p80 subunit B-like 1
chr17_-_26220366 0.51 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr3_-_172019686 0.50 ENST00000596321.1
AC092964.2
Uncharacterized protein
chr6_-_133055815 0.48 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr18_-_2982869 0.46 ENST00000584915.1
LPIN2
lipin 2
chr8_+_55466915 0.46 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr6_-_152623231 0.45 ENST00000540663.1
ENST00000537033.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_-_173886491 0.43 ENST00000367698.3
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr3_-_186262166 0.42 ENST00000307944.5
CRYGS
crystallin, gamma S
chr2_+_149974684 0.42 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr17_+_57274914 0.41 ENST00000582004.1
ENST00000577660.1
PRR11
CTD-2510F5.6
proline rich 11
Uncharacterized protein
chr9_-_34665983 0.41 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
RP11-195F19.5
HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr8_-_95220775 0.40 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr3_-_114790179 0.40 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr8_+_55467072 0.39 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr9_-_140082983 0.39 ENST00000323927.2
ANAPC2
anaphase promoting complex subunit 2
chr7_+_141463897 0.39 ENST00000247879.2
TAS2R3
taste receptor, type 2, member 3
chr6_-_33037019 0.38 ENST00000437811.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr17_+_38119216 0.38 ENST00000301659.4
GSDMA
gasdermin A
chr15_+_101389945 0.37 ENST00000561231.1
ENST00000559331.1
ENST00000558254.1
RP11-66B24.2
RP11-66B24.2
chr5_+_36608280 0.37 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_-_34207295 0.37 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr9_-_117853297 0.37 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
TNC
tenascin C
chr5_+_142286887 0.37 ENST00000451259.1
ARHGAP26
Rho GTPase activating protein 26
chr2_+_234160340 0.37 ENST00000417017.1
ENST00000392020.4
ENST00000392018.1
ATG16L1
autophagy related 16-like 1 (S. cerevisiae)
chr2_-_113594279 0.37 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr1_-_153113927 0.36 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr1_-_12679171 0.36 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr16_-_67881588 0.36 ENST00000561593.1
ENST00000565114.1
CENPT
centromere protein T
chr6_+_31916733 0.36 ENST00000483004.1
CFB
complement factor B
chr11_+_64052692 0.36 ENST00000377702.4
GPR137
G protein-coupled receptor 137
chr20_-_44516256 0.35 ENST00000372519.3
SPATA25
spermatogenesis associated 25
chr1_-_219615984 0.35 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr5_-_176936844 0.34 ENST00000510380.1
ENST00000510898.1
ENST00000357198.4
DOK3
docking protein 3
chr5_+_127039075 0.34 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chrX_-_84363974 0.34 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
SATL1
spermidine/spermine N1-acetyl transferase-like 1
chr11_-_10920838 0.34 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr22_+_30805086 0.33 ENST00000439838.1
ENST00000439023.3
RP4-539M6.19
Uncharacterized protein
chr3_-_100566492 0.33 ENST00000528490.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr17_-_57784755 0.32 ENST00000537860.1
ENST00000393038.2
ENST00000409433.2
PTRH2
peptidyl-tRNA hydrolase 2
chr6_-_154751629 0.32 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr7_+_144015218 0.32 ENST00000408951.1
OR2A1
olfactory receptor, family 2, subfamily A, member 1
chr5_-_162887054 0.32 ENST00000517501.1
NUDCD2
NudC domain containing 2
chr6_-_31940065 0.32 ENST00000375349.3
ENST00000337523.5
DXO
decapping exoribonuclease
chr6_+_143381979 0.32 ENST00000367598.5
ENST00000447498.1
ENST00000357847.4
ENST00000344492.5
ENST00000367596.1
ENST00000494282.2
ENST00000275235.4
AIG1
androgen-induced 1
chr12_-_7596735 0.32 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1
CD163 molecule-like 1
chr17_+_76210367 0.31 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr16_+_8814563 0.31 ENST00000425191.2
ENST00000569156.1
ABAT
4-aminobutyrate aminotransferase
chr20_-_52612468 0.30 ENST00000422805.1
BCAS1
breast carcinoma amplified sequence 1
chr3_-_110612323 0.30 ENST00000383686.2
RP11-553A10.1
Uncharacterized protein
chr1_+_16330723 0.29 ENST00000329454.2
C1orf64
chromosome 1 open reading frame 64
chr1_-_151319654 0.28 ENST00000430227.1
ENST00000412774.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr19_+_36545833 0.28 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WDR62
WD repeat domain 62
chr7_+_116593953 0.28 ENST00000397750.3
ST7-OT4
ST7 overlapping transcript 4
chr7_+_872107 0.28 ENST00000405266.1
ENST00000401592.1
ENST00000403868.1
ENST00000425407.2
SUN1
Sad1 and UNC84 domain containing 1
chr8_-_38386175 0.28 ENST00000437935.2
ENST00000358138.1
C8orf86
chromosome 8 open reading frame 86
chr6_-_170151603 0.27 ENST00000366774.3
TCTE3
t-complex-associated-testis-expressed 3
chr17_-_8021710 0.27 ENST00000380149.1
ENST00000448843.2
ALOXE3
arachidonate lipoxygenase 3
chrM_+_7586 0.27 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr7_-_143929936 0.27 ENST00000391496.1
OR2A42
olfactory receptor, family 2, subfamily A, member 42
chr19_+_36545781 0.27 ENST00000388999.3
WDR62
WD repeat domain 62
chr2_+_234160217 0.27 ENST00000392017.4
ENST00000347464.5
ENST00000444735.1
ENST00000373525.5
ENST00000419681.1
ATG16L1
autophagy related 16-like 1 (S. cerevisiae)
chr10_-_51958906 0.27 ENST00000489640.1
ASAH2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr11_+_64052266 0.26 ENST00000539851.1
GPR137
G protein-coupled receptor 137
chr20_+_57594309 0.26 ENST00000217133.1
TUBB1
tubulin, beta 1 class VI
chr1_-_11865982 0.26 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr17_-_40170506 0.26 ENST00000589773.1
ENST00000590348.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr7_-_41742697 0.26 ENST00000242208.4
INHBA
inhibin, beta A
chr4_+_71108300 0.26 ENST00000304954.3
CSN3
casein kappa
chr6_-_43027105 0.26 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
MRPL2
mitochondrial ribosomal protein L2
chr6_+_33043703 0.26 ENST00000418931.2
ENST00000535465.1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr4_+_185734773 0.25 ENST00000508020.1
RP11-701P16.2
Uncharacterized protein
chr6_+_30295036 0.25 ENST00000376659.5
ENST00000428555.1
TRIM39
tripartite motif containing 39
chr3_-_52488048 0.25 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr19_-_39881669 0.24 ENST00000221266.7
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr9_+_125027127 0.24 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
MRRF
mitochondrial ribosome recycling factor
chr1_-_151319318 0.24 ENST00000436271.1
ENST00000450506.1
ENST00000422595.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr4_+_71384257 0.24 ENST00000339336.4
AMTN
amelotin
chr3_-_27764190 0.23 ENST00000537516.1
EOMES
eomesodermin
chr6_+_30029008 0.23 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
ZNRD1
zinc ribbon domain containing 1
chr11_-_107729287 0.23 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr3_+_16926441 0.23 ENST00000418129.2
ENST00000396755.2
PLCL2
phospholipase C-like 2
chr5_-_140700322 0.23 ENST00000313368.5
TAF7
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
chr5_+_40909354 0.22 ENST00000313164.9
C7
complement component 7
chr10_+_35464513 0.22 ENST00000494479.1
ENST00000463314.1
ENST00000342105.3
ENST00000495301.1
ENST00000463960.1
CREM
cAMP responsive element modulator
chr10_+_69865866 0.22 ENST00000354393.2
MYPN
myopalladin
chr16_+_19467772 0.22 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5
transmembrane channel-like 5
chr4_+_26324474 0.22 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chrX_+_119029800 0.22 ENST00000371431.3
ENST00000371423.2
ENST00000371425.4
ENST00000394594.2
AKAP14
A kinase (PRKA) anchor protein 14
chr19_-_39881777 0.21 ENST00000595564.1
ENST00000221265.3
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr17_+_73663470 0.21 ENST00000583536.1
SAP30BP
SAP30 binding protein
chr22_+_32439019 0.21 ENST00000266088.4
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chrX_-_128782722 0.21 ENST00000427399.1
APLN
apelin
chr5_+_147582387 0.21 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr9_-_100684769 0.21 ENST00000455506.1
ENST00000375117.4
C9orf156
chromosome 9 open reading frame 156
chr15_-_43559055 0.21 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr19_-_36545649 0.21 ENST00000292894.1
THAP8
THAP domain containing 8
chrX_+_47078069 0.21 ENST00000357227.4
ENST00000519758.1
ENST00000520893.1
ENST00000517426.1
CDK16
cyclin-dependent kinase 16
chr12_+_57998400 0.21 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr19_+_44100632 0.21 ENST00000533118.1
ZNF576
zinc finger protein 576
chr8_+_22853345 0.21 ENST00000522948.1
RHOBTB2
Rho-related BTB domain containing 2
chr17_-_73663168 0.20 ENST00000578201.1
ENST00000423245.2
RECQL5
RecQ protein-like 5
chr5_-_160279207 0.20 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr14_-_75536182 0.20 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr6_-_31939734 0.20 ENST00000375356.3
DXO
decapping exoribonuclease
chr1_+_43735646 0.19 ENST00000439858.1
TMEM125
transmembrane protein 125
chr5_-_162887071 0.19 ENST00000302764.4
NUDCD2
NudC domain containing 2
chr6_-_3157760 0.19 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr1_-_155211017 0.19 ENST00000536770.1
ENST00000368373.3
GBA
glucosidase, beta, acid
chr21_+_36041688 0.19 ENST00000360731.3
ENST00000349499.2
CLIC6
chloride intracellular channel 6
chr19_+_47616682 0.19 ENST00000594526.1
SAE1
SUMO1 activating enzyme subunit 1
chr11_+_64052454 0.19 ENST00000539833.1
GPR137
G protein-coupled receptor 137
chr15_+_94899183 0.19 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr22_-_37505449 0.19 ENST00000406725.1
TMPRSS6
transmembrane protease, serine 6
chr1_+_45265897 0.19 ENST00000372201.4
PLK3
polo-like kinase 3
chrX_+_70503037 0.19 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chrX_+_100224676 0.19 ENST00000450049.2
ARL13A
ADP-ribosylation factor-like 13A
chr4_-_147442982 0.19 ENST00000511374.1
ENST00000264986.3
SLC10A7
solute carrier family 10, member 7
chr17_+_7461580 0.18 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr2_-_87018784 0.18 ENST00000283635.3
ENST00000538832.1
CD8A
CD8a molecule
chrX_+_49126294 0.18 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr1_+_198189921 0.18 ENST00000391974.3
NEK7
NIMA-related kinase 7
chr6_+_144185573 0.18 ENST00000237275.6
ENST00000539295.1
ZC2HC1B
zinc finger, C2HC-type containing 1B
chr14_+_35761540 0.18 ENST00000261479.4
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr19_-_58485895 0.18 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr11_+_57531292 0.18 ENST00000524579.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr3_+_45730829 0.18 ENST00000438671.1
SACM1L
SAC1 suppressor of actin mutations 1-like (yeast)
chr15_-_45406385 0.18 ENST00000389039.6
DUOX2
dual oxidase 2
chr3_+_63638372 0.18 ENST00000496807.1
SNTN
sentan, cilia apical structure protein
chr9_-_100684845 0.18 ENST00000375119.3
C9orf156
chromosome 9 open reading frame 156
chr2_-_68547061 0.18 ENST00000263655.3
CNRIP1
cannabinoid receptor interacting protein 1
chr11_-_125366089 0.18 ENST00000366139.3
ENST00000278919.3
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr16_-_46797149 0.18 ENST00000536476.1
MYLK3
myosin light chain kinase 3
chr9_+_140083099 0.18 ENST00000322310.5
SSNA1
Sjogren syndrome nuclear autoantigen 1
chr1_+_67632083 0.17 ENST00000347310.5
ENST00000371002.1
IL23R
interleukin 23 receptor
chr8_-_86141245 0.17 ENST00000546501.1
RP11-219B4.5
Uncharacterized protein
chr3_-_98241358 0.17 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr3_+_45730912 0.17 ENST00000541314.1
SACM1L
SAC1 suppressor of actin mutations 1-like (yeast)
chr5_+_147582348 0.17 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr1_+_207039154 0.17 ENST00000367096.3
ENST00000391930.2
IL20
interleukin 20
chr12_-_118628315 0.17 ENST00000540561.1
TAOK3
TAO kinase 3
chr18_-_70535177 0.17 ENST00000327305.6
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr12_-_18890940 0.17 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1
phospholipase C, zeta 1
chr17_-_39258461 0.17 ENST00000440582.1
KRTAP4-16P
keratin associated protein 4-16, pseudogene
chr11_+_7618413 0.17 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr7_+_6713376 0.17 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
AC073343.1
Uncharacterized protein
chr4_-_40632605 0.17 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr1_-_119682812 0.16 ENST00000537870.1
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
chr4_-_103749179 0.16 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr6_+_131958436 0.16 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr19_+_4402659 0.16 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr19_+_18699599 0.16 ENST00000450195.2
C19orf60
chromosome 19 open reading frame 60
chr14_-_21490653 0.16 ENST00000449431.2
NDRG2
NDRG family member 2
chr1_+_149239529 0.16 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr11_-_108093329 0.16 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr12_-_54813229 0.16 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr19_-_42721819 0.16 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
DEDD2
death effector domain containing 2
chr15_+_71228826 0.16 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr10_-_49860525 0.16 ENST00000435790.2
ARHGAP22
Rho GTPase activating protein 22
chr4_+_71384300 0.16 ENST00000504451.1
AMTN
amelotin
chr8_+_24151553 0.16 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr15_+_39311432 0.16 ENST00000560709.1
RP11-62C7.2
RP11-62C7.2
chr3_-_98241713 0.16 ENST00000502288.1
ENST00000512147.1
ENST00000510541.1
ENST00000503621.1
ENST00000511081.1
CLDND1
claudin domain containing 1
chr2_-_46769694 0.16 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr1_+_222817629 0.16 ENST00000340535.7
MIA3
melanoma inhibitory activity family, member 3
chr11_-_10920714 0.15 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr14_+_35761580 0.15 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr1_+_26517052 0.15 ENST00000338855.2
ENST00000456354.2
CATSPER4
cation channel, sperm associated 4
chr7_-_11871815 0.15 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr15_-_45406348 0.15 ENST00000603300.1
DUOX2
dual oxidase 2
chr11_-_126138808 0.15 ENST00000332118.6
ENST00000532259.1
SRPR
signal recognition particle receptor (docking protein)
chr4_+_165675197 0.15 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr6_+_143381594 0.15 ENST00000367601.4
AIG1
androgen-induced 1
chr12_-_53228079 0.15 ENST00000330553.5
KRT79
keratin 79
chr9_+_6757634 0.15 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C
lysine (K)-specific demethylase 4C
chr1_-_156265438 0.15 ENST00000362007.1
C1orf85
chromosome 1 open reading frame 85
chr15_+_28624878 0.15 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr15_-_42840961 0.14 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
LRRC57
leucine rich repeat containing 57
chr3_+_187957646 0.14 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_-_228244013 0.14 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr19_-_46142637 0.14 ENST00000590043.1
ENST00000589876.1
EML2
echinoderm microtubule associated protein like 2
chr2_-_225266743 0.14 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chr6_+_86195088 0.14 ENST00000437581.1
NT5E
5'-nucleotidase, ecto (CD73)
chr1_+_43613612 0.14 ENST00000335282.4
FAM183A
family with sequence similarity 183, member A
chr6_-_37467628 0.14 ENST00000373408.3
CCDC167
coiled-coil domain containing 167
chr1_-_40562908 0.14 ENST00000527311.2
ENST00000449045.2
ENST00000372779.4
PPT1
palmitoyl-protein thioesterase 1
chr1_-_183538319 0.14 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr19_+_41856816 0.14 ENST00000539627.1
TMEM91
transmembrane protein 91
chr9_-_123555655 0.14 ENST00000340778.5
ENST00000453291.1
ENST00000608872.1
FBXW2
F-box and WD repeat domain containing 2
chr4_-_69083720 0.14 ENST00000432593.3
TMPRSS11BNL
TMPRSS11B N-terminal like
chrX_-_30595959 0.14 ENST00000378962.3
CXorf21
chromosome X open reading frame 21
chr19_-_48018203 0.14 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr12_-_39734783 0.14 ENST00000552961.1
KIF21A
kinesin family member 21A

Network of associatons between targets according to the STRING database.

First level regulatory network of NFE2L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.4 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.2 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.1 0.3 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.6 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.3 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.3 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.2 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.3 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.4 GO:0031620 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.1 0.3 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.3 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.4 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) positive regulation of tooth mineralization(GO:0070172)
0.1 0.2 GO:0007343 egg activation(GO:0007343)
0.1 0.3 GO:0042335 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.8 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.4 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.2 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.3 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.3 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.3 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.0 0.1 GO:0019860 uracil metabolic process(GO:0019860) intestinal epithelial cell maturation(GO:0060574)
0.0 0.5 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.1 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.2 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0015846 polyamine transport(GO:0015846)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.0 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.3 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.5 GO:0007099 centriole replication(GO:0007099)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.1 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.0 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.5 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.4 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.5 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.2 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.3 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.3 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 0.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.3 GO:0034711 inhibin binding(GO:0034711)
0.1 1.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.4 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.6 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.0 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.4 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway