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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFKB2

Z-value: 1.33

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Transcription factors associated with NFKB2

Gene Symbol Gene ID Gene Info
NFKB2
ENSG00000077150.13 nuclear factor kappa B subunit 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB2hg19_v2_chr10_+_104155450_1041554790.882.1e-02Click!

Activity profile of NFKB2 motif

Sorted Z-values of NFKB2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_74904398 2.52 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr4_-_74864386 2.43 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr1_-_47655686 1.85 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr20_+_43803517 1.51 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr11_-_18270182 1.44 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr4_+_74735102 1.34 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr4_-_74964904 1.09 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr10_+_104154229 1.08 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr4_+_74702214 1.07 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr5_-_150466692 0.90 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr5_-_150467221 0.83 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr20_-_43753104 0.81 ENST00000372785.3
WFDC12
WAP four-disulfide core domain 12
chr2_+_74212073 0.79 ENST00000441217.1
AC073046.25
AC073046.25
chr12_-_49259643 0.73 ENST00000309739.5
RND1
Rho family GTPase 1
chr3_-_50340996 0.67 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr21_+_42741979 0.60 ENST00000543692.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr19_+_45504688 0.57 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr14_-_24729251 0.56 ENST00000559136.1
TGM1
transglutaminase 1
chr16_+_88704978 0.55 ENST00000244241.4
IL17C
interleukin 17C
chr14_-_24615805 0.49 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr17_+_40440481 0.47 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr15_-_43559055 0.47 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr2_+_64681641 0.46 ENST00000409537.2
LGALSL
lectin, galactoside-binding-like
chr8_-_90769422 0.46 ENST00000524190.1
ENST00000523859.1
RP11-37B2.1
RP11-37B2.1
chr5_-_60240858 0.44 ENST00000426742.2
ENST00000265038.5
ENST00000543101.1
ENST00000439176.1
ERCC8
excision repair cross-complementing rodent repair deficiency, complementation group 8
chr19_-_43835582 0.43 ENST00000595748.1
CTC-490G23.2
CTC-490G23.2
chr17_-_53499218 0.42 ENST00000571578.1
MMD
monocyte to macrophage differentiation-associated
chr2_+_132044330 0.42 ENST00000416266.1
CYP4F31P
cytochrome P450, family 4, subfamily F, polypeptide 31, pseudogene
chr16_+_28835766 0.42 ENST00000564656.1
ATXN2L
ataxin 2-like
chr9_+_130911723 0.41 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr6_+_14117872 0.41 ENST00000379153.3
CD83
CD83 molecule
chr16_+_2880157 0.40 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr1_-_183559693 0.40 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr1_-_183560011 0.39 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr16_+_31724618 0.39 ENST00000530881.1
ENST00000529515.1
ZNF720
zinc finger protein 720
chr12_+_93115281 0.39 ENST00000549856.1
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr15_+_101402041 0.39 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr19_+_15218180 0.38 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr5_+_176731572 0.38 ENST00000503853.1
PRELID1
PRELI domain containing 1
chr16_+_58497274 0.38 ENST00000564207.1
NDRG4
NDRG family member 4
chr9_+_130911770 0.37 ENST00000372998.1
LCN2
lipocalin 2
chr1_-_42921915 0.36 ENST00000372565.3
ENST00000433602.2
ZMYND12
zinc finger, MYND-type containing 12
chr3_+_111718173 0.35 ENST00000494932.1
TAGLN3
transgelin 3
chr2_+_99771527 0.35 ENST00000415142.1
ENST00000436234.1
LIPT1
lipoyltransferase 1
chr19_-_2090131 0.35 ENST00000591326.1
MOB3A
MOB kinase activator 3A
chr16_+_27279526 0.35 ENST00000566854.1
CTD-3203P2.2
HCG1815999; Uncharacterized protein
chr16_-_74734742 0.34 ENST00000308807.7
ENST00000573267.1
MLKL
mixed lineage kinase domain-like
chr17_+_46970134 0.34 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr14_-_21516590 0.33 ENST00000555026.1
NDRG2
NDRG family member 2
chr3_+_119814070 0.33 ENST00000469070.1
RP11-18H7.1
RP11-18H7.1
chr11_-_57335750 0.32 ENST00000340573.4
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr1_-_209824643 0.32 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr8_+_21777243 0.32 ENST00000521303.1
XPO7
exportin 7
chr17_-_18160584 0.31 ENST00000581349.1
ENST00000473425.2
FLII
flightless I homolog (Drosophila)
chr19_+_45251804 0.31 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr5_+_176730769 0.31 ENST00000303204.4
ENST00000503216.1
PRELID1
PRELI domain containing 1
chr14_-_24616426 0.31 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr3_+_52232102 0.31 ENST00000469224.1
ENST00000394965.2
ENST00000310271.2
ENST00000484952.1
ALAS1
aminolevulinate, delta-, synthase 1
chr2_-_241836298 0.30 ENST00000414499.1
C2orf54
chromosome 2 open reading frame 54
chr6_+_43968306 0.30 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr9_-_139268068 0.30 ENST00000371734.3
ENST00000371732.5
ENST00000315908.7
CARD9
caspase recruitment domain family, member 9
chr8_-_145641864 0.30 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr13_+_111972980 0.29 ENST00000283547.1
TEX29
testis expressed 29
chr9_-_140115775 0.29 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chr1_-_186649543 0.29 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr12_+_58176525 0.28 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr3_+_9850199 0.28 ENST00000452597.1
TTLL3
tubulin tyrosine ligase-like family, member 3
chr16_-_74734672 0.28 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr20_-_48532019 0.28 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr10_+_30722866 0.28 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr18_+_74240610 0.27 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
LINC00908
long intergenic non-protein coding RNA 908
chr16_-_1429010 0.27 ENST00000513783.1
UNKL
unkempt family zinc finger-like
chr16_+_67280799 0.26 ENST00000566345.2
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr16_+_28835437 0.26 ENST00000568266.1
ATXN2L
ataxin 2-like
chr11_-_3186551 0.26 ENST00000533234.1
OSBPL5
oxysterol binding protein-like 5
chr16_-_66959429 0.26 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr12_+_116955659 0.25 ENST00000552992.1
RP11-148B3.1
RP11-148B3.1
chr17_-_36997708 0.25 ENST00000398575.4
C17orf98
chromosome 17 open reading frame 98
chr8_+_95565947 0.25 ENST00000523011.1
RP11-267M23.4
RP11-267M23.4
chr1_-_173886491 0.25 ENST00000367698.3
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr5_+_142286887 0.25 ENST00000451259.1
ARHGAP26
Rho GTPase activating protein 26
chr10_+_112257596 0.25 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr12_+_120502441 0.25 ENST00000446727.2
CCDC64
coiled-coil domain containing 64
chrX_+_150151824 0.24 ENST00000455596.1
ENST00000448905.2
HMGB3
high mobility group box 3
chr12_+_120740119 0.24 ENST00000536460.1
ENST00000202967.4
SIRT4
sirtuin 4
chr1_+_150954493 0.24 ENST00000368947.4
ANXA9
annexin A9
chr5_+_60240943 0.24 ENST00000296597.5
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr17_-_53499310 0.24 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr6_-_143266297 0.23 ENST00000367603.2
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr14_+_21467414 0.23 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr18_-_6414797 0.23 ENST00000583809.1
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr6_-_24646249 0.23 ENST00000430948.2
ENST00000537886.1
ENST00000535378.1
ENST00000378214.3
KIAA0319
KIAA0319
chr8_-_9008206 0.22 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr2_-_27718052 0.22 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr2_-_70781087 0.22 ENST00000394241.3
ENST00000295400.6
TGFA
transforming growth factor, alpha
chr11_+_73000449 0.22 ENST00000535931.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr8_+_32406137 0.22 ENST00000521670.1
NRG1
neuregulin 1
chr17_-_39928106 0.22 ENST00000540235.1
JUP
junction plakoglobin
chr9_+_95909309 0.22 ENST00000366188.2
RP11-370F5.4
RP11-370F5.4
chr12_+_7023491 0.22 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr19_-_4338838 0.21 ENST00000594605.1
STAP2
signal transducing adaptor family member 2
chr17_+_40440094 0.21 ENST00000546010.2
STAT5A
signal transducer and activator of transcription 5A
chr20_+_58713514 0.21 ENST00000432910.1
RP5-1043L13.1
RP5-1043L13.1
chr2_+_173940163 0.21 ENST00000539448.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr11_-_3186494 0.21 ENST00000389989.3
ENST00000542243.1
OSBPL5
oxysterol binding protein-like 5
chrX_+_64887512 0.21 ENST00000360270.5
MSN
moesin
chr17_+_4854375 0.21 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
ENO3
enolase 3 (beta, muscle)
chr14_+_24605389 0.21 ENST00000382708.3
ENST00000561435.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr2_-_70780770 0.20 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr1_+_207494853 0.20 ENST00000367064.3
ENST00000367063.2
ENST00000391921.4
ENST00000367067.4
ENST00000314754.8
ENST00000367065.5
ENST00000391920.4
ENST00000367062.4
ENST00000343420.6
CD55
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chr20_+_61584026 0.20 ENST00000370351.4
ENST00000370349.3
SLC17A9
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr1_+_111770294 0.20 ENST00000474304.2
CHI3L2
chitinase 3-like 2
chr7_-_1595107 0.20 ENST00000414730.1
TMEM184A
transmembrane protein 184A
chr3_+_12329358 0.20 ENST00000309576.6
PPARG
peroxisome proliferator-activated receptor gamma
chr5_+_612387 0.20 ENST00000264935.5
ENST00000444221.1
CEP72
centrosomal protein 72kDa
chr17_-_47786375 0.19 ENST00000511657.1
SLC35B1
solute carrier family 35, member B1
chr11_-_8739383 0.19 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr6_-_31138439 0.19 ENST00000259915.8
POU5F1
POU class 5 homeobox 1
chr2_+_89952792 0.19 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr14_+_24605361 0.19 ENST00000206451.6
ENST00000559123.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr14_-_24615523 0.19 ENST00000559056.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr12_-_94673956 0.19 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr3_+_108308559 0.19 ENST00000486815.1
DZIP3
DAZ interacting zinc finger protein 3
chrX_-_24665208 0.19 ENST00000356768.4
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr7_+_1570322 0.19 ENST00000343242.4
MAFK
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr15_+_76030311 0.18 ENST00000543887.1
AC019294.1
AC019294.1
chr17_-_5487277 0.18 ENST00000572272.1
ENST00000354411.3
ENST00000577119.1
NLRP1
NLR family, pyrin domain containing 1
chr3_+_111718036 0.18 ENST00000455401.2
TAGLN3
transgelin 3
chr6_+_30978251 0.18 ENST00000561890.1
MUC22
mucin 22
chr2_+_24346324 0.18 ENST00000407625.1
ENST00000420135.2
FAM228B
family with sequence similarity 228, member B
chr19_-_4338783 0.18 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr14_-_75078725 0.18 ENST00000556690.1
LTBP2
latent transforming growth factor beta binding protein 2
chr11_+_61197572 0.18 ENST00000542074.1
ENST00000534878.1
ENST00000537782.1
ENST00000543265.1
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr15_+_77287426 0.18 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr22_+_44319648 0.17 ENST00000423180.2
PNPLA3
patatin-like phospholipase domain containing 3
chr1_-_71513471 0.17 ENST00000370931.3
ENST00000356595.4
ENST00000306666.5
ENST00000370932.2
ENST00000351052.5
ENST00000414819.1
ENST00000370924.4
PTGER3
prostaglandin E receptor 3 (subtype EP3)
chr17_-_9479128 0.17 ENST00000574431.1
STX8
syntaxin 8
chr9_+_139377947 0.17 ENST00000354376.1
C9orf163
chromosome 9 open reading frame 163
chr17_-_73267304 0.17 ENST00000579297.1
ENST00000580571.1
MIF4GD
MIF4G domain containing
chr6_-_10838736 0.17 ENST00000536370.1
ENST00000474039.1
MAK
male germ cell-associated kinase
chr6_-_31324943 0.17 ENST00000412585.2
ENST00000434333.1
HLA-B
major histocompatibility complex, class I, B
chr17_-_33415837 0.17 ENST00000414419.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr19_+_48898132 0.17 ENST00000263269.3
GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr3_+_23847394 0.17 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr14_+_23299088 0.17 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr11_-_33891362 0.16 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_+_60691924 0.16 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A
transmembrane protein 132A
chr17_+_46970127 0.16 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr3_+_157154578 0.16 ENST00000295927.3
PTX3
pentraxin 3, long
chrX_+_30671476 0.16 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
GK
glycerol kinase
chr5_+_53686658 0.16 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr8_-_66754172 0.16 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr7_-_111202511 0.16 ENST00000452895.1
ENST00000452753.1
ENST00000331762.3
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr19_-_47734448 0.16 ENST00000439096.2
BBC3
BCL2 binding component 3
chr12_+_112191694 0.15 ENST00000546840.2
RP11-162P23.2
RP11-162P23.2
chr17_-_7832753 0.15 ENST00000303790.2
KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr5_+_60241020 0.15 ENST00000511107.1
ENST00000502658.1
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr8_-_145653885 0.15 ENST00000531032.1
ENST00000292510.4
ENST00000377348.2
ENST00000530790.1
ENST00000533806.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr17_+_4855053 0.15 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr17_+_7462103 0.15 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr8_+_86376081 0.15 ENST00000285379.5
CA2
carbonic anhydrase II
chr2_+_173940668 0.15 ENST00000375213.3
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr10_+_99609996 0.15 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr22_+_44319619 0.15 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr19_+_45147313 0.15 ENST00000406449.4
PVR
poliovirus receptor
chrX_+_48755183 0.15 ENST00000376563.1
ENST00000376566.4
PQBP1
polyglutamine binding protein 1
chr3_+_113775576 0.15 ENST00000485050.1
ENST00000281273.4
QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr16_-_81110683 0.15 ENST00000565253.1
ENST00000378611.4
ENST00000299578.5
C16orf46
chromosome 16 open reading frame 46
chr3_+_111717600 0.15 ENST00000273368.4
TAGLN3
transgelin 3
chr17_-_1389228 0.15 ENST00000438665.2
MYO1C
myosin IC
chr5_-_176730676 0.15 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24
RAB24, member RAS oncogene family
chr16_+_50775948 0.15 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr8_+_128427857 0.15 ENST00000391675.1
POU5F1B
POU class 5 homeobox 1B
chr2_+_173940442 0.14 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr17_+_9548845 0.14 ENST00000570475.1
ENST00000285199.7
USP43
ubiquitin specific peptidase 43
chr19_+_45147098 0.14 ENST00000425690.3
ENST00000344956.4
ENST00000403059.4
PVR
poliovirus receptor
chr6_-_2962331 0.14 ENST00000380524.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr6_+_129204337 0.14 ENST00000421865.2
LAMA2
laminin, alpha 2
chr11_-_2924720 0.14 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr6_-_10838710 0.14 ENST00000313243.2
MAK
male germ cell-associated kinase
chr17_-_1389419 0.14 ENST00000575158.1
MYO1C
myosin IC
chr12_-_62997214 0.14 ENST00000408887.2
C12orf61
chromosome 12 open reading frame 61
chr12_+_56473939 0.13 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr12_-_56753858 0.13 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr16_+_89894875 0.13 ENST00000393062.2
SPIRE2
spire-type actin nucleation factor 2
chr13_-_111214015 0.13 ENST00000267328.3
RAB20
RAB20, member RAS oncogene family
chrX_-_2418596 0.13 ENST00000381218.3
ZBED1
zinc finger, BED-type containing 1
chr6_-_44095183 0.13 ENST00000372014.3
MRPL14
mitochondrial ribosomal protein L14
chr14_+_97263641 0.13 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr18_+_21529811 0.13 ENST00000588004.1
LAMA3
laminin, alpha 3
chr12_+_110011571 0.13 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr1_-_47082495 0.13 ENST00000545730.1
ENST00000531769.1
ENST00000319928.3
MKNK1
MOB3C
MAP kinase interacting serine/threonine kinase 1
MOB kinase activator 3C
chr11_-_8739566 0.13 ENST00000533020.1
ST5
suppression of tumorigenicity 5
chr1_-_89458287 0.13 ENST00000370485.2
CCBL2
cysteine conjugate-beta lyase 2
chr9_-_139965000 0.13 ENST00000409687.3
SAPCD2
suppressor APC domain containing 2
chr19_-_5978144 0.13 ENST00000340578.6
ENST00000541471.1
ENST00000591736.1
ENST00000587479.1
RANBP3
RAN binding protein 3
chr16_-_88878305 0.13 ENST00000569616.1
ENST00000563655.1
ENST00000567713.1
ENST00000426324.2
ENST00000378364.3
APRT
adenine phosphoribosyltransferase
chr11_-_27722021 0.13 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
BDNF
brain-derived neurotrophic factor
chr20_-_48330377 0.12 ENST00000371711.4
B4GALT5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr1_-_154943212 0.12 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1
SHC (Src homology 2 domain containing) transforming protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.3 1.7 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 8.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.2 0.8 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.7 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.7 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.7 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 0.3 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.2 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 1.5 GO:0007620 copulation(GO:0007620)
0.1 0.6 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.2 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.5 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.2 GO:1901558 pancreatic stellate cell proliferation(GO:0072343) response to metformin(GO:1901558) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.2 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.2 GO:0042938 positive regulation of cellular pH reduction(GO:0032849) dipeptide transport(GO:0042938)
0.1 0.2 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.2 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.2 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.8 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.3 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.4 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.7 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.3 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0001878 response to yeast(GO:0001878)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.6 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.3 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.2 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0052031 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0 0.8 GO:0045730 respiratory burst(GO:0045730)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.3 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.4 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 1.4 GO:0006953 acute-phase response(GO:0006953)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.0 GO:0008089 anterograde axonal transport(GO:0008089) axonal transport(GO:0098930)
0.0 0.3 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.1 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:1903971 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.0 0.2 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.6 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 0.0 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.4 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.1 GO:0090166 histone H3-S10 phosphorylation(GO:0043987) Golgi disassembly(GO:0090166)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.0 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.0 GO:0051097 negative regulation of helicase activity(GO:0051097) cellular response to actinomycin D(GO:0072717)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 1.4 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.4 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.0 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 1.4 GO:0008537 proteasome activator complex(GO:0008537)
0.2 0.7 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 0.8 GO:0032010 phagolysosome(GO:0032010)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.2 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 0.2 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.0 1.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 2.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.5 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.8 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.0 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 1.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.3 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.3 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.1 0.2 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.6 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 1.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.3 GO:0030297 ErbB-2 class receptor binding(GO:0005176) transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.4 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.0 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.1 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 5.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 2.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway