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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NKX2-1

Z-value: 0.63

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Transcription factors associated with NKX2-1

Gene Symbol Gene ID Gene Info
NKX2-1
ENSG00000136352.13 NK2 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-1hg19_v2_chr14_-_36990061_369901540.522.9e-01Click!

Activity profile of NKX2-1 motif

Sorted Z-values of NKX2-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_41240717 0.32 ENST00000379561.5
FOXO1
forkhead box O1
chr12_+_25205446 0.31 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr6_-_113953705 0.29 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr2_-_25451065 0.29 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr3_+_187930491 0.25 ENST00000443217.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr12_+_25205568 0.24 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr1_-_156269428 0.23 ENST00000339922.3
VHLL
von Hippel-Lindau tumor suppressor-like
chr2_+_99797636 0.22 ENST00000409145.1
MRPL30
mitochondrial ribosomal protein L30
chr2_-_85895295 0.22 ENST00000428225.1
ENST00000519937.2
SFTPB
surfactant protein B
chr22_-_30925150 0.22 ENST00000437871.1
SEC14L6
SEC14-like 6 (S. cerevisiae)
chrX_-_108976410 0.22 ENST00000504980.1
ACSL4
acyl-CoA synthetase long-chain family member 4
chr19_+_48958766 0.21 ENST00000342291.2
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr16_-_18937072 0.21 ENST00000569122.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr12_+_25205666 0.20 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr15_-_66790146 0.20 ENST00000316634.5
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr20_-_45142154 0.18 ENST00000347606.4
ENST00000457685.2
ZNF334
zinc finger protein 334
chr14_-_73360796 0.18 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr15_-_42448788 0.17 ENST00000382396.4
ENST00000397272.3
PLA2G4F
phospholipase A2, group IVF
chr19_+_50148087 0.17 ENST00000601038.1
ENST00000595242.1
SCAF1
SR-related CTD-associated factor 1
chr1_+_202431859 0.17 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr8_+_70404996 0.17 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr7_+_99156249 0.17 ENST00000449244.1
ZNF655
zinc finger protein 655
chr12_+_25205628 0.16 ENST00000554942.1
LRMP
lymphoid-restricted membrane protein
chr19_-_39390350 0.16 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr19_-_17622269 0.16 ENST00000595116.1
CTD-3131K8.2
CTD-3131K8.2
chr8_-_80680078 0.15 ENST00000337919.5
ENST00000354724.3
HEY1
hes-related family bHLH transcription factor with YRPW motif 1
chr10_-_7708918 0.14 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr4_+_26165074 0.14 ENST00000512351.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr5_+_140345820 0.14 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr3_-_49837254 0.14 ENST00000412678.2
ENST00000343366.4
ENST00000487256.1
CDHR4
cadherin-related family member 4
chr10_-_98031310 0.13 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr14_+_74353320 0.13 ENST00000540593.1
ENST00000555730.1
ZNF410
zinc finger protein 410
chr1_-_220101944 0.13 ENST00000366926.3
ENST00000536992.1
SLC30A10
solute carrier family 30, member 10
chr3_+_32726774 0.13 ENST00000538368.1
CNOT10
CCR4-NOT transcription complex, subunit 10
chr1_-_236445251 0.13 ENST00000354619.5
ENST00000327333.8
ERO1LB
ERO1-like beta (S. cerevisiae)
chr21_-_36421401 0.12 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr17_-_8198636 0.12 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr3_+_23847432 0.12 ENST00000346855.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr12_+_56401268 0.12 ENST00000262032.5
IKZF4
IKAROS family zinc finger 4 (Eos)
chr10_+_63808970 0.12 ENST00000309334.5
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr10_-_98031265 0.12 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chrX_+_86772787 0.12 ENST00000373114.4
KLHL4
kelch-like family member 4
chr3_+_4535025 0.12 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr15_+_40453204 0.11 ENST00000287598.6
ENST00000412359.3
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
chrX_+_134478706 0.11 ENST00000370761.3
ENST00000339249.4
ENST00000370760.3
ZNF449
zinc finger protein 449
chr8_-_62602327 0.11 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr12_+_50479101 0.11 ENST00000551966.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr10_-_79397547 0.11 ENST00000481070.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr11_+_115498761 0.11 ENST00000424313.2
AP000997.1
AP000997.1
chr15_+_77287426 0.11 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr1_-_68698222 0.10 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr22_+_24891210 0.10 ENST00000382760.2
UPB1
ureidopropionase, beta
chr3_+_172361483 0.10 ENST00000598405.1
AC007919.2
HCG1787166; PRO1163; Uncharacterized protein
chr1_+_204485571 0.10 ENST00000454264.2
ENST00000367183.3
MDM4
Mdm4 p53 binding protein homolog (mouse)
chr19_-_36231437 0.09 ENST00000591748.1
IGFLR1
IGF-like family receptor 1
chr4_+_184826418 0.09 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr17_+_26646175 0.09 ENST00000583381.1
ENST00000582113.1
ENST00000582384.1
TMEM97
transmembrane protein 97
chr14_+_67708344 0.09 ENST00000557237.1
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr1_+_32930647 0.09 ENST00000609129.1
ZBTB8B
zinc finger and BTB domain containing 8B
chrX_+_22056165 0.09 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr19_+_1942453 0.09 ENST00000591752.1
CSNK1G2
casein kinase 1, gamma 2
chr13_+_95364963 0.09 ENST00000438290.2
SOX21-AS1
SOX21 antisense RNA 1 (head to head)
chr1_-_153538292 0.08 ENST00000497140.1
ENST00000368708.3
S100A2
S100 calcium binding protein A2
chr5_+_96077888 0.08 ENST00000509259.1
ENST00000503828.1
CAST
calpastatin
chr5_+_140079919 0.08 ENST00000274712.3
ZMAT2
zinc finger, matrin-type 2
chr3_+_4535155 0.08 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr19_-_38720354 0.08 ENST00000416611.1
DPF1
D4, zinc and double PHD fingers family 1
chr6_-_41673552 0.08 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr16_+_1359138 0.08 ENST00000325437.5
UBE2I
ubiquitin-conjugating enzyme E2I
chr6_-_137113604 0.08 ENST00000359015.4
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr9_+_129986734 0.08 ENST00000444677.1
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr11_-_105948040 0.08 ENST00000534815.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr6_+_32121218 0.08 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2
palmitoyl-protein thioesterase 2
chr17_-_42466864 0.07 ENST00000353281.4
ENST00000262407.5
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chrX_+_131157322 0.07 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4
Serine/threonine-protein kinase MST4
chr1_-_10003372 0.07 ENST00000377223.1
ENST00000541052.1
ENST00000377213.1
LZIC
leucine zipper and CTNNBIP1 domain containing
chr16_+_5121814 0.07 ENST00000262374.5
ENST00000586840.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr3_+_187930429 0.07 ENST00000420410.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr14_+_74815116 0.07 ENST00000256362.4
VRTN
vertebrae development associated
chr3_-_113464906 0.07 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr11_+_35160709 0.07 ENST00000415148.2
ENST00000433354.2
ENST00000449691.2
ENST00000437706.2
ENST00000360158.4
ENST00000428726.2
ENST00000526669.2
ENST00000433892.2
ENST00000278386.6
ENST00000434472.2
ENST00000352818.4
ENST00000442151.2
CD44
CD44 molecule (Indian blood group)
chr17_+_26646121 0.07 ENST00000226230.6
TMEM97
transmembrane protein 97
chr1_+_228337553 0.07 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr1_-_153538011 0.07 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr4_-_819901 0.07 ENST00000304062.6
CPLX1
complexin 1
chr1_-_41487415 0.07 ENST00000372611.1
SLFNL1
schlafen-like 1
chr12_+_50478977 0.07 ENST00000381513.4
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr3_+_39149145 0.07 ENST00000301819.6
ENST00000431162.2
TTC21A
tetratricopeptide repeat domain 21A
chr15_-_33360085 0.07 ENST00000334528.9
FMN1
formin 1
chr17_+_73642486 0.07 ENST00000579469.1
SMIM6
small integral membrane protein 6
chrX_+_131157290 0.07 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chrX_-_83442915 0.07 ENST00000262752.2
ENST00000543399.1
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr18_+_33877654 0.07 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3
formin homology 2 domain containing 3
chr6_+_32121789 0.06 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chrX_-_30326445 0.06 ENST00000378963.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr3_-_42744312 0.06 ENST00000416756.1
ENST00000441594.1
HHATL
hedgehog acyltransferase-like
chr14_+_67708137 0.06 ENST00000556345.1
ENST00000555925.1
ENST00000557783.1
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr8_-_144679602 0.06 ENST00000526710.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr19_+_24009879 0.06 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr17_+_40610862 0.06 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chrX_-_119693745 0.06 ENST00000371323.2
CUL4B
cullin 4B
chrX_+_86772707 0.06 ENST00000373119.4
KLHL4
kelch-like family member 4
chr2_+_220379052 0.06 ENST00000347842.3
ENST00000358078.4
ASIC4
acid-sensing (proton-gated) ion channel family member 4
chr7_-_105332084 0.06 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr3_-_52029958 0.06 ENST00000294189.6
RPL29
ribosomal protein L29
chr22_-_30968839 0.06 ENST00000445645.1
ENST00000416358.1
ENST00000423371.1
ENST00000411821.1
ENST00000448604.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr2_+_152266604 0.06 ENST00000430328.2
RIF1
RAP1 interacting factor homolog (yeast)
chr2_-_175870085 0.06 ENST00000409156.3
CHN1
chimerin 1
chr8_+_132916318 0.06 ENST00000254624.5
ENST00000522709.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr15_-_44955842 0.06 ENST00000427534.2
ENST00000559193.1
ENST00000261866.7
ENST00000535302.2
ENST00000558319.1
SPG11
spastic paraplegia 11 (autosomal recessive)
chr3_+_187930719 0.06 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_-_176033066 0.05 ENST00000437522.1
ATF2
activating transcription factor 2
chr14_-_58893832 0.05 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr9_-_5830768 0.05 ENST00000381506.3
ERMP1
endoplasmic reticulum metallopeptidase 1
chr8_-_94752946 0.05 ENST00000519109.1
RBM12B
RNA binding motif protein 12B
chr12_+_121837905 0.05 ENST00000392465.3
ENST00000554606.1
ENST00000392464.2
ENST00000555076.1
RNF34
ring finger protein 34, E3 ubiquitin protein ligase
chr12_+_93772326 0.05 ENST00000550056.1
ENST00000549992.1
ENST00000548662.1
ENST00000547014.1
NUDT4
nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr9_-_72374848 0.05 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
PTAR1
protein prenyltransferase alpha subunit repeat containing 1
chr2_-_152118352 0.05 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr1_-_41487383 0.05 ENST00000302946.8
ENST00000372613.2
ENST00000439569.2
ENST00000397197.2
SLFNL1
schlafen-like 1
chr9_+_33290491 0.05 ENST00000379540.3
ENST00000379521.4
ENST00000318524.6
NFX1
nuclear transcription factor, X-box binding 1
chr7_-_95064264 0.05 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
PON2
paraoxonase 2
chr2_-_225266802 0.05 ENST00000243806.2
FAM124B
family with sequence similarity 124B
chr1_-_160232197 0.05 ENST00000419626.1
ENST00000610139.1
ENST00000475733.1
ENST00000407642.2
ENST00000368073.3
ENST00000326837.2
DCAF8
DDB1 and CUL4 associated factor 8
chr17_-_60005365 0.05 ENST00000444766.3
INTS2
integrator complex subunit 2
chr17_+_26684604 0.04 ENST00000292114.3
ENST00000509083.1
TMEM199
transmembrane protein 199
chr12_+_7941989 0.04 ENST00000229307.4
NANOG
Nanog homeobox
chr5_-_146889619 0.04 ENST00000343218.5
DPYSL3
dihydropyrimidinase-like 3
chr17_+_59489112 0.04 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr2_+_128848740 0.04 ENST00000375990.3
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr17_-_60005329 0.04 ENST00000251334.6
INTS2
integrator complex subunit 2
chr1_-_228604328 0.04 ENST00000355586.4
ENST00000366698.2
ENST00000520264.1
ENST00000479800.1
ENST00000295033.3
TRIM17
tripartite motif containing 17
chr6_-_134373732 0.04 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chrX_-_134478012 0.04 ENST00000370766.3
ZNF75D
zinc finger protein 75D
chr7_+_65338230 0.04 ENST00000360768.3
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr3_-_42744270 0.04 ENST00000457462.1
HHATL
hedgehog acyltransferase-like
chr12_+_121416489 0.04 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr17_-_37123646 0.04 ENST00000378079.2
FBXO47
F-box protein 47
chr7_-_142583478 0.04 ENST00000436401.1
TRPV6
transient receptor potential cation channel, subfamily V, member 6
chrX_-_70473957 0.04 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3
zinc finger, MYM-type 3
chr13_-_46425865 0.04 ENST00000400405.2
SIAH3
siah E3 ubiquitin protein ligase family member 3
chr19_-_10679644 0.04 ENST00000393599.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr16_-_58663720 0.03 ENST00000564557.1
ENST00000569240.1
ENST00000441024.2
ENST00000569020.1
ENST00000317147.5
CNOT1
CCR4-NOT transcription complex, subunit 1
chrX_-_70474499 0.03 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr12_-_21810765 0.03 ENST00000450584.1
ENST00000350669.1
LDHB
lactate dehydrogenase B
chr5_+_134094461 0.03 ENST00000452510.2
ENST00000354283.4
DDX46
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr17_+_61554829 0.03 ENST00000582627.1
ACE
angiotensin I converting enzyme
chr15_+_57511609 0.03 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12
transcription factor 12
chr11_-_105948129 0.03 ENST00000526793.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr17_+_73642315 0.03 ENST00000556126.2
SMIM6
small integral membrane protein 6
chr14_+_81421921 0.03 ENST00000554263.1
ENST00000554435.1
TSHR
thyroid stimulating hormone receptor
chr10_+_111967345 0.03 ENST00000332674.5
ENST00000453116.1
MXI1
MAX interactor 1, dimerization protein
chr11_+_105948216 0.03 ENST00000278618.4
AASDHPPT
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr6_+_31554779 0.03 ENST00000376090.2
LST1
leukocyte specific transcript 1
chr17_+_76210367 0.03 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr20_+_58152524 0.03 ENST00000359926.3
PHACTR3
phosphatase and actin regulator 3
chr15_+_76030311 0.03 ENST00000543887.1
AC019294.1
AC019294.1
chr16_-_29757272 0.03 ENST00000329410.3
C16orf54
chromosome 16 open reading frame 54
chr1_-_153518270 0.03 ENST00000354332.4
ENST00000368716.4
S100A4
S100 calcium binding protein A4
chr16_+_28303804 0.03 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr8_-_114389353 0.03 ENST00000343508.3
CSMD3
CUB and Sushi multiple domains 3
chr8_+_94752349 0.03 ENST00000391680.1
RBM12B-AS1
RBM12B antisense RNA 1
chr1_+_178694300 0.03 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr2_-_225266711 0.03 ENST00000389874.3
FAM124B
family with sequence similarity 124B
chr12_+_50479109 0.03 ENST00000550477.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr21_+_33671264 0.03 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr12_-_21810726 0.03 ENST00000396076.1
LDHB
lactate dehydrogenase B
chr17_+_59529743 0.03 ENST00000589003.1
ENST00000393853.4
TBX4
T-box 4
chr9_+_133986782 0.03 ENST00000372301.2
AIF1L
allograft inflammatory factor 1-like
chr4_+_55524085 0.03 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr17_-_34195862 0.02 ENST00000592980.1
ENST00000587626.1
C17orf66
chromosome 17 open reading frame 66
chr9_-_14313641 0.02 ENST00000380953.1
NFIB
nuclear factor I/B
chrX_+_23928500 0.02 ENST00000435707.1
CXorf58
chromosome X open reading frame 58
chr4_-_155471528 0.02 ENST00000302078.5
ENST00000499023.2
PLRG1
pleiotropic regulator 1
chr5_+_131705438 0.02 ENST00000245407.3
SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr16_+_71929397 0.02 ENST00000537613.1
ENST00000424485.2
ENST00000606369.1
ENST00000329908.8
ENST00000538850.1
ENST00000541918.1
ENST00000534994.1
ENST00000378798.5
ENST00000539186.1
IST1
increased sodium tolerance 1 homolog (yeast)
chr8_+_37654693 0.02 ENST00000412232.2
GPR124
G protein-coupled receptor 124
chr2_+_85646054 0.02 ENST00000389938.2
SH2D6
SH2 domain containing 6
chr15_-_94614049 0.02 ENST00000556447.1
ENST00000555772.1
CTD-3049M7.1
CTD-3049M7.1
chr5_-_137548997 0.02 ENST00000505120.1
ENST00000394886.2
ENST00000394884.3
CDC23
cell division cycle 23
chr8_+_77596014 0.02 ENST00000523885.1
ZFHX4
zinc finger homeobox 4
chr19_+_1065922 0.02 ENST00000539243.2
HMHA1
histocompatibility (minor) HA-1
chrX_-_70474377 0.02 ENST00000373978.1
ENST00000373981.1
ZMYM3
zinc finger, MYM-type 3
chr15_+_69452959 0.02 ENST00000261858.2
GLCE
glucuronic acid epimerase
chr17_-_40169429 0.02 ENST00000316603.7
ENST00000588641.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr2_-_230787879 0.02 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr17_-_76778339 0.02 ENST00000591455.1
ENST00000446868.3
ENST00000361101.4
ENST00000589296.1
CYTH1
cytohesin 1
chr1_-_153599426 0.02 ENST00000392622.1
S100A13
S100 calcium binding protein A13
chr2_-_225266743 0.02 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chr1_-_175712665 0.02 ENST00000263525.2
TNR
tenascin R
chr22_-_30968813 0.02 ENST00000443111.2
ENST00000443136.1
ENST00000426220.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr19_+_39390320 0.02 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr1_-_62190793 0.02 ENST00000371177.2
ENST00000606498.1
TM2D1
TM2 domain containing 1
chr15_-_43029252 0.02 ENST00000563260.1
ENST00000356231.3
CDAN1
codanin 1
chr17_-_34195889 0.01 ENST00000311880.2
C17orf66
chromosome 17 open reading frame 66
chr21_+_45773515 0.01 ENST00000397932.2
ENST00000300481.9
TRPM2
transient receptor potential cation channel, subfamily M, member 2
chr9_+_109685630 0.01 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr8_+_145065705 0.01 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr2_+_99797542 0.01 ENST00000338148.3
ENST00000512183.2
MRPL30
C2orf15
mitochondrial ribosomal protein L30
chromosome 2 open reading frame 15
chr20_+_30407151 0.01 ENST00000375985.4
MYLK2
myosin light chain kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0 0.1 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.1 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.0 0.2 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.1 GO:0060254 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.0 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.0 GO:0035623 renal glucose absorption(GO:0035623)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0043219 lateral loop(GO:0043219)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.5 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.0 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.0 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells