Project

NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for NKX2-4

Z-value: 1.45

Motif logo

Transcription factors associated with NKX2-4

Gene Symbol Gene ID Gene Info
ENSG00000125816.4 NK2 homeobox 4

Activity profile of NKX2-4 motif

Sorted Z-values of NKX2-4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_3469181 1.02 ENST00000366116.2
Uncharacterized protein
chr22_-_18923655 0.81 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
proline dehydrogenase (oxidase) 1
chr6_-_30899924 0.76 ENST00000359086.3
surfactant associated 2
chr2_+_109065634 0.74 ENST00000409821.1
GRIP and coiled-coil domain containing 2
chr1_-_89458287 0.67 ENST00000370485.2
cysteine conjugate-beta lyase 2
chr12_-_58329888 0.66 ENST00000546580.1
RP11-620J15.3
chr8_+_42396712 0.66 ENST00000518574.1
ENST00000417410.2
ENST00000414154.2
small integral membrane protein 19
chr2_-_188419078 0.65 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr11_-_111383064 0.65 ENST00000525791.1
ENST00000456861.2
ENST00000356018.2
B-cell translocation gene 4
chr10_-_28571015 0.61 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr19_-_55669093 0.58 ENST00000344887.5
troponin I type 3 (cardiac)
chr11_+_60699222 0.57 ENST00000536409.1
transmembrane protein 132A
chr1_+_144989309 0.55 ENST00000596396.1
Uncharacterized protein
chr1_+_158901329 0.54 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
pyrin and HIN domain family, member 1
chr8_+_103876528 0.54 ENST00000522939.1
ENST00000524007.1
HCG15011, isoform CRA_a; Protein LOC100996457
chr7_+_129932974 0.53 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
carboxypeptidase A4
chr19_-_41942344 0.52 ENST00000594660.1
ATP5S-like
chr1_-_100643765 0.50 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
leucine rich repeat containing 39
chr11_-_14521349 0.49 ENST00000534234.1
coatomer protein complex, subunit beta 1
chr19_-_12444519 0.48 ENST00000595977.1
zinc finger protein 563
chr6_-_56492816 0.48 ENST00000522360.1
dystonin
chr9_-_88874519 0.48 ENST00000376001.3
ENST00000339137.3
chromosome 9 open reading frame 153
chr4_+_86748898 0.47 ENST00000509300.1
Rho GTPase activating protein 24
chr1_-_85040090 0.46 ENST00000370630.5
chitobiase, di-N-acetyl-
chr18_+_9136758 0.46 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ankyrin repeat domain 12
chr8_+_67687773 0.45 ENST00000518388.1
serum/glucocorticoid regulated kinase family, member 3
chr5_-_42811986 0.45 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr1_+_110036728 0.45 ENST00000369868.3
ENST00000430195.2
cytochrome b561 family, member D1
chr5_-_42812143 0.45 ENST00000514985.1
selenoprotein P, plasma, 1
chr13_-_41240717 0.45 ENST00000379561.5
forkhead box O1
chr8_+_136469684 0.44 ENST00000355849.5
KH domain containing, RNA binding, signal transduction associated 3
chr1_-_204183071 0.44 ENST00000308302.3
golgi transport 1A
chr18_-_60985914 0.43 ENST00000589955.1
B-cell CLL/lymphoma 2
chr12_-_53601000 0.42 ENST00000338737.4
ENST00000549086.2
integrin, beta 7
chr15_+_34394257 0.42 ENST00000397766.2
piggyBac transposable element derived 4
chr18_-_28622699 0.41 ENST00000360428.4
desmocollin 3
chr19_-_49843539 0.41 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
chr17_-_41050716 0.41 ENST00000417193.1
ENST00000301683.3
ENST00000436546.1
ENST00000431109.2
long intergenic non-protein coding RNA 671
chr2_-_85828867 0.40 ENST00000425160.1
transmembrane protein 150A
chr1_+_61869748 0.40 ENST00000357977.5
nuclear factor I/A
chr18_-_28622774 0.39 ENST00000434452.1
desmocollin 3
chr11_-_104035088 0.39 ENST00000302251.5
platelet derived growth factor D
chr4_-_175443943 0.39 ENST00000296522.6
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr15_+_63354769 0.39 ENST00000558910.1
tropomyosin 1 (alpha)
chr2_+_161993465 0.38 ENST00000457476.1
TRAF family member-associated NFKB activator
chr10_+_99332529 0.38 ENST00000455090.1
ankyrin repeat domain 2 (stretch responsive muscle)
chr11_+_35965531 0.38 ENST00000528989.1
ENST00000524419.1
ENST00000315571.5
low density lipoprotein receptor class A domain containing 3
chr15_-_34394008 0.36 ENST00000527822.1
ENST00000528949.1
ER membrane protein complex subunit 7
chr10_-_18944123 0.36 ENST00000606425.1
Uncharacterized protein
chr1_-_197744763 0.36 ENST00000422998.1
DENN/MADD domain containing 1B
chr1_+_202431859 0.35 ENST00000391959.3
ENST00000367270.4
protein phosphatase 1, regulatory subunit 12B
chr7_-_105221898 0.35 ENST00000486180.1
ENST00000485614.1
ENST00000480514.1
EF-hand calcium binding domain 10
chrX_+_148622138 0.34 ENST00000450602.2
ENST00000441248.1
chromosome X open reading frame 40A
chr3_-_107777208 0.34 ENST00000398258.3
CD47 molecule
chr4_-_100242549 0.34 ENST00000305046.8
ENST00000394887.3
alcohol dehydrogenase 1B (class I), beta polypeptide
chr1_+_110036699 0.34 ENST00000496961.1
ENST00000533024.1
ENST00000310611.4
ENST00000527072.1
ENST00000420578.2
ENST00000528785.1
cytochrome b561 family, member D1
chr14_-_59932044 0.34 ENST00000395116.1
G protein-coupled receptor 135
chr1_+_222886694 0.33 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BRO1 domain and CAAX motif containing
chr1_-_70671216 0.33 ENST00000370952.3
leucine rich repeat containing 40
chr4_+_90033968 0.32 ENST00000317005.2
tigger transposable element derived 2
chr4_-_75695366 0.32 ENST00000512743.1
betacellulin
chr8_+_42396936 0.32 ENST00000416469.2
small integral membrane protein 19
chr2_-_188419200 0.32 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr21_-_16374688 0.31 ENST00000411932.1
nuclear receptor interacting protein 1
chr4_-_48683188 0.31 ENST00000505759.1
FRY-like
chr20_+_55108302 0.31 ENST00000371325.1
family with sequence similarity 209, member B
chr15_-_31523036 0.31 ENST00000559094.1
ENST00000558388.2
RP11-16E12.2
chr17_+_42977122 0.31 ENST00000412523.2
ENST00000331733.4
ENST00000417826.2
family with sequence similarity 187, member A
coiled-coil domain containing 103
chr7_-_54826869 0.31 ENST00000450622.1
Sec61 gamma subunit
chr17_-_19648416 0.31 ENST00000426645.2
aldehyde dehydrogenase 3 family, member A1
chr7_+_36450169 0.30 ENST00000428612.1
anillin, actin binding protein
chr1_-_222886526 0.30 ENST00000541237.1
axin interactor, dorsalization associated
chr4_+_129349188 0.29 ENST00000511497.1
RP11-420A23.1
chr10_-_65225641 0.29 ENST00000399262.2
jumonji domain containing 1C
chr15_-_33180439 0.29 ENST00000559610.1
formin 1
chr1_-_115301235 0.29 ENST00000525878.1
cold shock domain containing E1, RNA-binding
chr12_+_133757995 0.29 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
zinc finger protein 268
chr16_+_8736232 0.28 ENST00000562973.1
methyltransferase like 22
chr12_+_21590549 0.28 ENST00000545178.1
ENST00000240651.9
pyridine nucleotide-disulphide oxidoreductase domain 1
chr1_-_57431679 0.28 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
complement component 8, beta polypeptide
chr2_-_55920952 0.28 ENST00000447944.2
polyribonucleotide nucleotidyltransferase 1
chr12_-_53601055 0.28 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
integrin, beta 7
chr6_+_159071015 0.28 ENST00000360448.3
synaptotagmin-like 3
chr7_+_65552756 0.28 ENST00000450043.1
AC068533.7
chr8_+_97597148 0.28 ENST00000521590.1
syndecan 2
chr18_+_11851383 0.27 ENST00000526991.2
charged multivesicular body protein 1B
chr6_+_7590413 0.27 ENST00000342415.5
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr6_-_73935163 0.27 ENST00000370388.3
KH homology domain containing 1-like
chr6_-_31088214 0.27 ENST00000376288.2
corneodesmosin
chr2_+_183982255 0.27 ENST00000455063.1
nucleoporin 35kDa
chr10_+_60094735 0.27 ENST00000373910.4
ubiquitin-conjugating enzyme E2D 1
chr12_-_113658892 0.27 ENST00000299732.2
ENST00000416617.2
IQ motif containing D
chr13_-_108870623 0.26 ENST00000405925.1
ligase IV, DNA, ATP-dependent
chr7_-_152373216 0.26 ENST00000359321.1
X-ray repair complementing defective repair in Chinese hamster cells 2
chr19_-_12444306 0.26 ENST00000594577.1
ENST00000601858.1
zinc finger protein 563
chr5_+_154135453 0.25 ENST00000517616.1
ENST00000518892.1
La ribonucleoprotein domain family, member 1
chr10_-_65225722 0.25 ENST00000399251.1
jumonji domain containing 1C
chr21_-_15918618 0.25 ENST00000400564.1
ENST00000400566.1
SAM domain, SH3 domain and nuclear localization signals 1
chr18_-_29340827 0.25 ENST00000269205.5
solute carrier family 25, member 52
chr7_+_133812052 0.25 ENST00000285928.2
leucine-rich repeats and guanylate kinase domain containing
chr11_+_33037652 0.25 ENST00000311388.3
DEP domain containing 7
chr14_-_34420259 0.25 ENST00000250457.3
ENST00000547327.2
egl-9 family hypoxia-inducible factor 3
chr10_-_13544945 0.24 ENST00000378605.3
ENST00000341083.3
BEN domain containing 7
chr5_-_39270725 0.24 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr15_-_83474806 0.24 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
fibronectin type III and SPRY domain containing 2
chr12_+_128399965 0.24 ENST00000540882.1
ENST00000542089.1
long intergenic non-protein coding RNA 507
chrX_+_105936982 0.24 ENST00000418562.1
ring finger protein 128, E3 ubiquitin protein ligase
chr13_-_96705624 0.24 ENST00000376747.3
ENST00000376712.4
ENST00000397618.3
ENST00000376714.3
UDP-glucose glycoprotein glucosyltransferase 2
chr4_-_68411275 0.24 ENST00000273853.6
centromere protein C
chr4_-_87028478 0.24 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr3_-_88108192 0.24 ENST00000309534.6
CGG triplet repeat binding protein 1
chr3_+_177159744 0.24 ENST00000439009.1
long intergenic non-protein coding RNA 578
chr1_-_223308098 0.23 ENST00000342210.6
toll-like receptor 5
chr2_+_120687335 0.23 ENST00000544261.1
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr13_-_36944307 0.23 ENST00000355182.4
spastic paraplegia 20 (Troyer syndrome)
chr13_-_108867846 0.23 ENST00000442234.1
ligase IV, DNA, ATP-dependent
chr7_+_75932863 0.23 ENST00000429938.1
heat shock 27kDa protein 1
chr2_+_10560147 0.23 ENST00000422133.1
hippocalcin-like 1
chr19_-_17559376 0.23 ENST00000341130.5
transmembrane protein 221
chr17_+_42923686 0.23 ENST00000591513.1
HIG1 hypoxia inducible domain family, member 1B
chr3_+_124303512 0.23 ENST00000454902.1
kalirin, RhoGEF kinase
chr14_+_45464658 0.23 ENST00000555874.1
family with sequence similarity 179, member B
chr5_-_78808617 0.23 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
homer homolog 1 (Drosophila)
chr14_+_65381079 0.23 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr5_-_68339648 0.23 ENST00000479830.2
CTC-498J12.1
chr11_-_85780853 0.22 ENST00000531930.1
ENST00000528398.1
phosphatidylinositol binding clathrin assembly protein
chr17_-_5138099 0.22 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr19_-_20748541 0.22 ENST00000427401.4
ENST00000594419.1
zinc finger protein 737
chr2_-_37899323 0.22 ENST00000295324.3
ENST00000457889.1
CDC42 effector protein (Rho GTPase binding) 3
chr1_-_47407136 0.22 ENST00000462347.1
ENST00000371905.1
ENST00000310638.4
cytochrome P450, family 4, subfamily A, polypeptide 11
chr17_-_38574169 0.22 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr2_-_169887827 0.22 ENST00000263817.6
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr19_-_20748614 0.22 ENST00000596797.1
zinc finger protein 737
chr18_+_21032781 0.22 ENST00000339486.3
RIO kinase 3
chr10_+_81272287 0.22 ENST00000520547.2
eukaryotic translation initiation factor 5A-like 1
chr16_-_31100284 0.22 ENST00000280606.6
protease, serine, 53
chr14_+_51955831 0.22 ENST00000356218.4
FERM domain containing 6
chr12_+_128399917 0.21 ENST00000544645.1
long intergenic non-protein coding RNA 507
chr17_+_66244071 0.21 ENST00000580548.1
ENST00000580753.1
ENST00000392720.2
ENST00000359783.4
ENST00000584837.1
ENST00000579724.1
ENST00000584494.1
ENST00000580837.1
archaelysin family metallopeptidase 2
chrX_-_54069576 0.21 ENST00000445025.1
ENST00000322659.8
PHD finger protein 8
chr1_+_95583479 0.21 ENST00000455656.1
ENST00000604534.1
transmembrane protein 56
TMEM56-RWDD3 readthrough
chr2_-_225434538 0.21 ENST00000409096.1
cullin 3
chr9_+_71986182 0.21 ENST00000303068.7
family with sequence similarity 189, member A2
chrX_-_44402231 0.21 ENST00000378045.4
FUN14 domain containing 1
chr12_+_133758115 0.21 ENST00000541009.2
ENST00000592241.1
zinc finger protein 268
chr22_+_25465786 0.21 ENST00000401395.1
KIAA1671
chr13_-_52026730 0.20 ENST00000420668.2
integrator complex subunit 6
chr2_-_202483867 0.20 ENST00000439802.1
ENST00000286195.3
ENST00000439140.1
ENST00000450242.1
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11
chr3_-_126327398 0.20 ENST00000383572.2
thioredoxin reductase 3 neighbor
chr18_+_61445205 0.20 ENST00000431370.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr2_+_204571198 0.20 ENST00000374481.3
ENST00000458610.2
ENST00000324106.8
CD28 molecule
chr2_-_175462934 0.19 ENST00000392546.2
ENST00000436221.1
WAS/WASL interacting protein family, member 1
chr2_-_179315786 0.19 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
protein kinase, interferon-inducible double stranded RNA dependent activator
chr8_-_7320974 0.19 ENST00000528943.1
ENST00000359758.5
ENST00000361111.2
ENST00000398462.2
ENST00000297498.2
ENST00000317900.5
sperm associated antigen 11B
chr8_+_7705398 0.19 ENST00000400125.2
ENST00000434307.2
ENST00000326558.5
ENST00000351436.4
ENST00000528033.1
sperm associated antigen 11A
chr2_+_191221240 0.19 ENST00000409027.1
ENST00000458193.1
inositol polyphosphate-1-phosphatase
chr6_-_134861089 0.19 ENST00000606039.1
RP11-557H15.4
chr8_+_74206829 0.19 ENST00000240285.5
retinol dehydrogenase 10 (all-trans)
chr2_-_25451065 0.18 ENST00000606328.1
RP11-458N5.1
chr2_+_172309634 0.18 ENST00000339506.3
DDB1 and CUL4 associated factor 17
chr6_-_28303901 0.18 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
zinc finger and SCAN domain containing 31
chr5_+_64064748 0.18 ENST00000381070.3
ENST00000508024.1
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr4_+_102734967 0.18 ENST00000444316.2
B-cell scaffold protein with ankyrin repeats 1
chr4_-_103746683 0.18 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr15_+_44719996 0.18 ENST00000559793.1
ENST00000558968.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr19_-_12444491 0.18 ENST00000293725.5
zinc finger protein 563
chr4_-_178363581 0.18 ENST00000264595.2
aspartylglucosaminidase
chr6_-_143832793 0.18 ENST00000438118.2
fucosidase, alpha-L- 2, plasma
chr7_-_92463210 0.18 ENST00000265734.4
cyclin-dependent kinase 6
chr4_-_69111401 0.18 ENST00000332644.5
transmembrane protease, serine 11B
chr10_+_22605374 0.18 ENST00000448361.1
COMM domain containing 3
chr21_+_40823753 0.17 ENST00000333634.4
SH3 domain binding glutamic acid-rich protein
chr5_-_34919094 0.17 ENST00000341754.4
RAD1 homolog (S. pombe)
chr22_-_26961328 0.17 ENST00000398110.2
tyrosylprotein sulfotransferase 2
chr7_+_134551583 0.17 ENST00000435928.1
caldesmon 1
chr4_+_3768075 0.16 ENST00000509482.1
ENST00000330055.5
adrenoceptor alpha 2C
chr6_+_45390222 0.16 ENST00000359524.5
runt-related transcription factor 2
chr14_+_62229075 0.16 ENST00000216294.4
small nuclear RNA activating complex, polypeptide 1, 43kDa
chr2_+_103378472 0.16 ENST00000412401.2
transmembrane protein 182
chr12_-_102591604 0.16 ENST00000329406.4
pro-melanin-concentrating hormone
chr14_+_78266408 0.16 ENST00000238561.5
aarF domain containing kinase 1
chrX_-_138914394 0.16 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATPase, class VI, type 11C
chr6_-_149969871 0.16 ENST00000335643.8
ENST00000444282.1
katanin p60 (ATPase containing) subunit A 1
chr11_+_61717842 0.16 ENST00000449131.2
bestrophin 1
chr4_-_175041663 0.16 ENST00000503140.1
RP11-148L24.1
chr4_-_103746924 0.16 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
ubiquitin-conjugating enzyme E2D 3
chr11_+_19138670 0.16 ENST00000446113.2
ENST00000399351.3
zinc finger, DHHC-type containing 13
chr11_-_105892937 0.16 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr12_+_18891045 0.15 ENST00000317658.3
capping protein (actin filament) muscle Z-line, alpha 3
chr6_+_153552455 0.15 ENST00000392385.2
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr14_-_81408093 0.15 ENST00000555265.1
centrosomal protein 128kDa
chr1_+_87794150 0.15 ENST00000370544.5
LIM domain only 4
chr12_+_123011776 0.15 ENST00000450485.2
ENST00000333479.7
kinetochore associated 1
chr1_-_89591749 0.15 ENST00000370466.3
guanylate binding protein 2, interferon-inducible
chr2_+_205410723 0.15 ENST00000358768.2
ENST00000351153.1
ENST00000349953.3
par-3 family cell polarity regulator beta
chr4_-_168155169 0.15 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr10_+_98592674 0.15 ENST00000356016.3
ENST00000371097.4
ligand dependent nuclear receptor corepressor
chr14_-_23451467 0.15 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
ajuba LIM protein
chr14_+_56078695 0.15 ENST00000416613.1
kinectin 1 (kinesin receptor)
chr19_+_7953417 0.15 ENST00000600345.1
ENST00000598224.1
leucine rich repeat containing 8 family, member E

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0006562 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.2 1.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.7 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.2 0.5 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.2 0.5 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.7 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.4 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.1 0.4 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.3 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.3 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.1 0.3 GO:2000625 rRNA import into mitochondrion(GO:0035928) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.1 0.3 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.2 GO:0097359 UDP-glucosylation(GO:0097359)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.1 0.2 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.3 GO:0003335 corneocyte development(GO:0003335)
0.1 0.4 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.5 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.2 GO:0032811 regulation of epinephrine secretion(GO:0014060) negative regulation of epinephrine secretion(GO:0032811) epinephrine secretion(GO:0048242)
0.1 0.2 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.2 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.2 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.3 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.5 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.3 GO:0008228 opsonization(GO:0008228)
0.0 0.2 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.3 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.6 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0 0.4 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.3 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.4 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.3 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.0 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.1 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.4 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.0 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.2 GO:0031274 regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.0 0.3 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.0 GO:0002892 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) regulation of type II hypersensitivity(GO:0002892) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.0 0.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:0002442 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.5 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0032059 bleb(GO:0032059)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.1 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.4 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.4 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.2 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.2 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.1 0.6 GO:0030172 troponin C binding(GO:0030172)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.2 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.5 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.8 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle