Project

NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for NKX2-8

Z-value: 0.68

Motif logo

logo of

Transcription factors associated with NKX2-8

Gene Symbol Gene ID Gene Info
NKX2-8
ENSG00000136327.6 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-8hg19_v2_chr14_-_37051798_37051831-0.157.7e-01Click!

Activity profile of NKX2-8 motif

Sorted Z-values of NKX2-8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_27998689 0.82 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
IFI6
interferon, alpha-inducible protein 6
chr2_-_25451065 0.53 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr17_+_67590125 0.53 ENST00000591334.1
AC003051.1
AC003051.1
chrX_+_115567767 0.42 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr5_-_176056974 0.39 ENST00000510387.1
ENST00000506696.1
SNCB
synuclein, beta
chr1_+_10057274 0.38 ENST00000294435.7
RBP7
retinol binding protein 7, cellular
chr3_+_177545563 0.32 ENST00000434309.1
RP11-91K9.1
RP11-91K9.1
chr22_+_38609538 0.31 ENST00000407965.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr6_+_43968306 0.31 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr14_-_24732403 0.28 ENST00000206765.6
TGM1
transglutaminase 1
chr2_-_36779411 0.28 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr3_+_172361483 0.27 ENST00000598405.1
AC007919.2
HCG1787166; PRO1163; Uncharacterized protein
chr16_+_23194033 0.25 ENST00000300061.2
SCNN1G
sodium channel, non-voltage-gated 1, gamma subunit
chr6_+_41010293 0.25 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
TSPO2
translocator protein 2
chr2_+_119699864 0.23 ENST00000541757.1
ENST00000412481.1
MARCO
macrophage receptor with collagenous structure
chr17_+_76210367 0.22 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr2_-_159313214 0.20 ENST00000409889.1
ENST00000283233.5
ENST00000536771.1
CCDC148
coiled-coil domain containing 148
chr3_+_126423045 0.20 ENST00000290913.3
ENST00000508789.1
CHCHD6
coiled-coil-helix-coiled-coil-helix domain containing 6
chr14_-_24732368 0.20 ENST00000544573.1
TGM1
transglutaminase 1
chr7_-_127671674 0.19 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr12_+_49658855 0.19 ENST00000549183.1
TUBA1C
tubulin, alpha 1c
chr2_+_119699742 0.17 ENST00000327097.4
MARCO
macrophage receptor with collagenous structure
chr8_+_107593198 0.17 ENST00000517686.1
OXR1
oxidation resistance 1
chr14_+_58894404 0.17 ENST00000554463.1
ENST00000555833.1
KIAA0586
KIAA0586
chr11_-_128457446 0.16 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr3_-_16524357 0.16 ENST00000432519.1
RFTN1
raftlin, lipid raft linker 1
chr1_-_95007193 0.16 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr1_+_228337553 0.15 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr2_+_101591314 0.15 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr2_-_68547061 0.15 ENST00000263655.3
CNRIP1
cannabinoid receptor interacting protein 1
chr4_+_76481258 0.15 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr21_+_33671160 0.15 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr3_+_239652 0.15 ENST00000435603.1
CHL1
cell adhesion molecule L1-like
chr18_-_72920372 0.14 ENST00000581620.1
ENST00000582437.1
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr12_+_13349711 0.14 ENST00000538364.1
ENST00000396301.3
EMP1
epithelial membrane protein 1
chr7_-_766879 0.14 ENST00000537384.1
ENST00000417852.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr12_+_66218903 0.14 ENST00000393577.3
HMGA2
high mobility group AT-hook 2
chr8_+_105602961 0.13 ENST00000521923.1
RP11-127H5.1
Uncharacterized protein
chr3_+_67048721 0.13 ENST00000295568.4
ENST00000484414.1
ENST00000460576.1
ENST00000417314.2
KBTBD8
kelch repeat and BTB (POZ) domain containing 8
chr18_+_44497455 0.13 ENST00000592005.1
KATNAL2
katanin p60 subunit A-like 2
chr17_+_61086917 0.13 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chrX_+_48681768 0.12 ENST00000430858.1
HDAC6
histone deacetylase 6
chr22_+_39101728 0.12 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr8_-_29120604 0.12 ENST00000521515.1
KIF13B
kinesin family member 13B
chr15_-_60683326 0.12 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
ANXA2
annexin A2
chr22_-_32341336 0.11 ENST00000248984.3
C22orf24
chromosome 22 open reading frame 24
chr15_-_35047166 0.10 ENST00000290374.4
GJD2
gap junction protein, delta 2, 36kDa
chr12_+_7941989 0.10 ENST00000229307.4
NANOG
Nanog homeobox
chr4_-_100485143 0.10 ENST00000394877.3
TRMT10A
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr8_-_29120580 0.10 ENST00000524189.1
KIF13B
kinesin family member 13B
chr16_+_58426296 0.10 ENST00000426538.2
ENST00000328514.7
ENST00000318129.5
GINS3
GINS complex subunit 3 (Psf3 homolog)
chrM_+_8366 0.10 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chrX_-_69479654 0.10 ENST00000374519.2
P2RY4
pyrimidinergic receptor P2Y, G-protein coupled, 4
chr19_-_39881669 0.10 ENST00000221266.7
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr10_-_135171178 0.10 ENST00000368551.1
FUOM
fucose mutarotase
chr18_+_3450161 0.09 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr1_+_180165672 0.09 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr5_-_95158644 0.09 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr21_+_33671264 0.09 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr3_-_52739670 0.09 ENST00000497953.1
GLT8D1
glycosyltransferase 8 domain containing 1
chr3_-_114790179 0.09 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr7_-_95025661 0.09 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
PON1
PON3
paraoxonase 1
paraoxonase 3
chr11_+_59705928 0.09 ENST00000398992.1
OOSP1
oocyte secreted protein 1
chr20_-_48747662 0.09 ENST00000371656.2
TMEM189
transmembrane protein 189
chr18_+_13382553 0.09 ENST00000586222.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr8_+_23430157 0.09 ENST00000399967.3
FP15737
FP15737
chr6_-_133084580 0.09 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2
vanin 2
chr4_-_7873713 0.08 ENST00000382543.3
AFAP1
actin filament associated protein 1
chr5_+_35852797 0.08 ENST00000508941.1
IL7R
interleukin 7 receptor
chr16_+_67034466 0.08 ENST00000535696.1
CES4A
carboxylesterase 4A
chr16_+_67034456 0.08 ENST00000540579.1
CES4A
carboxylesterase 4A
chr14_-_58894332 0.08 ENST00000395159.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr8_-_81083341 0.08 ENST00000519303.2
TPD52
tumor protein D52
chr4_-_819901 0.08 ENST00000304062.6
CPLX1
complexin 1
chr16_+_29674540 0.08 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
SPN
QPRT
sialophorin
quinolinate phosphoribosyltransferase
chr17_+_7591639 0.07 ENST00000396463.2
WRAP53
WD repeat containing, antisense to TP53
chr12_-_10320190 0.07 ENST00000543993.1
ENST00000339968.6
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr7_-_127672146 0.07 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr14_-_58894223 0.07 ENST00000555593.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr11_+_18417948 0.07 ENST00000542179.1
LDHA
lactate dehydrogenase A
chr4_-_100485183 0.07 ENST00000394876.2
TRMT10A
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr10_-_14596140 0.07 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr1_+_151512775 0.07 ENST00000368849.3
ENST00000392712.3
ENST00000353024.3
ENST00000368848.2
ENST00000538902.1
TUFT1
tuftelin 1
chr12_+_60058458 0.07 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr1_+_55464600 0.06 ENST00000371265.4
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr3_+_111717511 0.06 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr6_-_137113604 0.06 ENST00000359015.4
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr17_-_9808887 0.06 ENST00000226193.5
RCVRN
recoverin
chr7_+_18330035 0.06 ENST00000413509.2
HDAC9
histone deacetylase 9
chr16_-_3767506 0.06 ENST00000538171.1
TRAP1
TNF receptor-associated protein 1
chr11_-_72353451 0.06 ENST00000376450.3
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr2_+_204801471 0.06 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chrM_+_8527 0.06 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr11_-_72353494 0.06 ENST00000544570.1
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr6_+_30844192 0.06 ENST00000502955.1
ENST00000505066.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr9_+_131873842 0.06 ENST00000417728.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr7_+_30634297 0.06 ENST00000389266.3
GARS
glycyl-tRNA synthetase
chr20_+_47835884 0.06 ENST00000371764.4
DDX27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr1_+_41157361 0.06 ENST00000427410.2
ENST00000447388.3
ENST00000425457.2
ENST00000453631.1
ENST00000456393.2
NFYC
nuclear transcription factor Y, gamma
chr12_-_49504449 0.06 ENST00000547675.1
LMBR1L
limb development membrane protein 1-like
chr8_-_144679264 0.05 ENST00000531953.1
ENST00000526133.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr3_-_8811288 0.05 ENST00000316793.3
ENST00000431493.1
OXTR
oxytocin receptor
chr21_-_35899113 0.05 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr19_+_34856141 0.05 ENST00000586425.1
GPI
glucose-6-phosphate isomerase
chr4_-_153601136 0.05 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr1_+_154401791 0.05 ENST00000476006.1
IL6R
interleukin 6 receptor
chr19_-_38720354 0.05 ENST00000416611.1
DPF1
D4, zinc and double PHD fingers family 1
chrX_-_63450480 0.05 ENST00000362002.2
ASB12
ankyrin repeat and SOCS box containing 12
chr16_-_66952779 0.05 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
CDH16
cadherin 16, KSP-cadherin
chr16_-_30441293 0.05 ENST00000565758.1
ENST00000567983.1
ENST00000319285.4
DCTPP1
dCTP pyrophosphatase 1
chr3_+_111717600 0.05 ENST00000273368.4
TAGLN3
transgelin 3
chr5_+_176692466 0.05 ENST00000508029.1
ENST00000503056.1
NSD1
nuclear receptor binding SET domain protein 1
chr2_-_151905288 0.05 ENST00000409243.1
AC023469.1
HCG1817310; Uncharacterized protein
chr16_-_3767551 0.05 ENST00000246957.5
TRAP1
TNF receptor-associated protein 1
chr6_-_32806506 0.05 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr18_-_44497308 0.05 ENST00000585916.1
ENST00000324794.7
ENST00000545673.1
PIAS2
protein inhibitor of activated STAT, 2
chr19_-_44259053 0.05 ENST00000601170.1
SMG9
SMG9 nonsense mediated mRNA decay factor
chr1_+_74701062 0.05 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chrX_-_64196307 0.05 ENST00000545618.1
ZC4H2
zinc finger, C4H2 domain containing
chr8_+_128426535 0.05 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chr15_-_77363375 0.05 ENST00000559494.1
TSPAN3
tetraspanin 3
chr17_-_62502399 0.05 ENST00000450599.2
ENST00000585060.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr6_+_34433844 0.05 ENST00000244458.2
ENST00000374043.2
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr8_-_125551278 0.04 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TATDN1
TatD DNase domain containing 1
chr20_-_57089934 0.04 ENST00000439429.1
ENST00000371149.3
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chr17_-_62502639 0.04 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr2_+_62132800 0.04 ENST00000538736.1
COMMD1
copper metabolism (Murr1) domain containing 1
chr17_+_37784749 0.04 ENST00000394265.1
ENST00000394267.2
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr16_-_66952742 0.04 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16
cadherin 16, KSP-cadherin
chrX_-_9754333 0.04 ENST00000447366.1
GPR143
G protein-coupled receptor 143
chr11_-_67141640 0.04 ENST00000533438.1
CLCF1
cardiotrophin-like cytokine factor 1
chr3_-_196242233 0.04 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr1_-_217262969 0.04 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr12_+_13349650 0.04 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr6_-_32145861 0.04 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr2_-_151395525 0.04 ENST00000439275.1
RND3
Rho family GTPase 3
chr10_-_118032697 0.04 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr3_-_116163830 0.04 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr15_+_74911430 0.04 ENST00000562670.1
ENST00000564096.1
CLK3
CDC-like kinase 3
chr19_+_52074502 0.04 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
ZNF175
zinc finger protein 175
chr3_-_58613323 0.04 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr3_-_73673991 0.04 ENST00000308537.4
ENST00000263666.4
PDZRN3
PDZ domain containing ring finger 3
chr10_+_71078595 0.04 ENST00000359426.6
HK1
hexokinase 1
chr1_+_16083098 0.04 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr17_-_62503015 0.04 ENST00000581806.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr17_+_73455788 0.04 ENST00000581519.1
KIAA0195
KIAA0195
chr1_-_94147385 0.04 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr19_+_34856078 0.04 ENST00000589399.1
ENST00000589640.1
ENST00000591204.1
GPI
glucose-6-phosphate isomerase
chr19_-_44259136 0.03 ENST00000270066.6
SMG9
SMG9 nonsense mediated mRNA decay factor
chrX_-_110039286 0.03 ENST00000434224.1
CHRDL1
chordin-like 1
chr1_-_217262933 0.03 ENST00000359162.2
ESRRG
estrogen-related receptor gamma
chr15_-_77363513 0.03 ENST00000267970.4
TSPAN3
tetraspanin 3
chr5_-_179107975 0.03 ENST00000376974.4
CBY3
chibby homolog 3 (Drosophila)
chr8_+_67341239 0.03 ENST00000320270.2
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr1_+_224301787 0.03 ENST00000366862.5
ENST00000424254.2
FBXO28
F-box protein 28
chr4_-_100484825 0.03 ENST00000273962.3
ENST00000514547.1
ENST00000455368.2
TRMT10A
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr14_+_76618242 0.03 ENST00000557542.1
ENST00000557263.1
ENST00000557207.1
ENST00000312858.5
ENST00000261530.7
GPATCH2L
G patch domain containing 2-like
chr3_+_173302222 0.03 ENST00000361589.4
NLGN1
neuroligin 1
chr1_+_12040238 0.03 ENST00000444836.1
ENST00000235329.5
MFN2
mitofusin 2
chr15_+_86686953 0.03 ENST00000421325.2
AGBL1
ATP/GTP binding protein-like 1
chr6_+_143772060 0.03 ENST00000367591.4
PEX3
peroxisomal biogenesis factor 3
chr12_-_49504655 0.03 ENST00000551782.1
ENST00000267102.8
LMBR1L
limb development membrane protein 1-like
chr17_+_46184911 0.03 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
SNX11
sorting nexin 11
chrX_-_48776292 0.03 ENST00000376509.4
PIM2
pim-2 oncogene
chrX_-_110655306 0.03 ENST00000371993.2
DCX
doublecortin
chr2_-_136288740 0.03 ENST00000264159.6
ENST00000536680.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr3_-_187455680 0.03 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr17_-_46178527 0.03 ENST00000393408.3
CBX1
chromobox homolog 1
chr12_-_118406777 0.03 ENST00000339824.5
KSR2
kinase suppressor of ras 2
chr2_+_207024306 0.03 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr6_+_69942298 0.03 ENST00000238918.8
BAI3
brain-specific angiogenesis inhibitor 3
chr15_-_77363441 0.03 ENST00000346495.2
ENST00000424443.3
ENST00000561277.1
TSPAN3
tetraspanin 3
chr17_+_62503073 0.02 ENST00000580188.1
ENST00000581056.1
CEP95
centrosomal protein 95kDa
chr12_-_75603202 0.02 ENST00000393288.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr17_-_33390667 0.02 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr8_+_27182862 0.02 ENST00000521164.1
ENST00000346049.5
PTK2B
protein tyrosine kinase 2 beta
chr11_-_104827425 0.02 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr13_+_46039037 0.02 ENST00000349995.5
COG3
component of oligomeric golgi complex 3
chr15_+_40453204 0.02 ENST00000287598.6
ENST00000412359.3
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
chr17_+_7591747 0.02 ENST00000534050.1
WRAP53
WD repeat containing, antisense to TP53
chr19_-_11347173 0.02 ENST00000587656.1
DOCK6
dedicator of cytokinesis 6
chr3_-_53164423 0.02 ENST00000467048.1
ENST00000394738.3
ENST00000296292.3
RFT1
RFT1 homolog (S. cerevisiae)
chr7_-_92855762 0.02 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr1_-_104239302 0.02 ENST00000446703.1
AMY1B
amylase, alpha 1B (salivary)
chr3_-_114343768 0.02 ENST00000393785.2
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_68547019 0.02 ENST00000409862.1
CNRIP1
cannabinoid receptor interacting protein 1
chr7_-_156803329 0.02 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr17_-_79623597 0.02 ENST00000574024.1
ENST00000331056.5
PDE6G
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr1_+_41157421 0.02 ENST00000372654.1
NFYC
nuclear transcription factor Y, gamma
chr1_-_155006224 0.02 ENST00000368424.3
DCST2
DC-STAMP domain containing 2
chr22_+_21213771 0.02 ENST00000439214.1
SNAP29
synaptosomal-associated protein, 29kDa
chr12_-_12837423 0.02 ENST00000540510.1
GPR19
G protein-coupled receptor 19
chr15_-_99057551 0.02 ENST00000558256.1
FAM169B
family with sequence similarity 169, member B
chr2_-_207023918 0.02 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_+_76251912 0.02 ENST00000370826.3
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr7_+_30811004 0.02 ENST00000265299.6
FAM188B
family with sequence similarity 188, member B
chr5_+_74011328 0.02 ENST00000513336.1
HEXB
hexosaminidase B (beta polypeptide)
chr11_+_64808675 0.02 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr6_-_55740352 0.02 ENST00000370830.3
BMP5
bone morphogenetic protein 5
chr18_-_56296182 0.02 ENST00000361673.3
ALPK2
alpha-kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:1904180 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.1 0.5 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0031049 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0044035 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0060455 positive regulation of norepinephrine secretion(GO:0010701) negative regulation of gastric acid secretion(GO:0060455)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.0 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:0015966 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.0 0.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0060180 female mating behavior(GO:0060180)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.3 GO:0007567 parturition(GO:0007567)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.4 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.0 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.0 GO:0035643 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly