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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NKX3-1

Z-value: 0.98

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Transcription factors associated with NKX3-1

Gene Symbol Gene ID Gene Info
NKX3-1
ENSG00000167034.9 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX3-1hg19_v2_chr8_-_23540402_23540466-0.236.6e-01Click!

Activity profile of NKX3-1 motif

Sorted Z-values of NKX3-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_54609230 0.68 ENST00000420296.1
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr11_-_104480019 0.67 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr1_-_152779104 0.65 ENST00000606576.1
ENST00000368768.1
LCE1C
late cornified envelope 1C
chr19_-_12708113 0.65 ENST00000440366.1
ZNF490
zinc finger protein 490
chr6_+_26251835 0.61 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr16_+_1832902 0.55 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr1_-_153113927 0.54 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr12_-_92536433 0.53 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr1_-_203273676 0.52 ENST00000425698.1
RP11-134P9.1
long intergenic non-protein coding RNA 1136
chr16_+_47496023 0.52 ENST00000567200.1
PHKB
phosphorylase kinase, beta
chr1_-_153066998 0.49 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chrY_+_15418467 0.49 ENST00000595988.1
AC010877.1
Uncharacterized protein
chr19_-_45457264 0.49 ENST00000591646.1
CTB-129P6.11
Uncharacterized protein
chr11_-_64684672 0.46 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr14_+_101293687 0.46 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr19_+_56111680 0.43 ENST00000301073.3
ZNF524
zinc finger protein 524
chr4_+_159131596 0.41 ENST00000512481.1
TMEM144
transmembrane protein 144
chr19_-_44174330 0.40 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr12_-_92821922 0.38 ENST00000538965.1
ENST00000378487.2
CLLU1OS
chronic lymphocytic leukemia up-regulated 1 opposite strand
chr15_-_74726283 0.38 ENST00000543145.2
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr3_-_49726104 0.38 ENST00000383728.3
ENST00000545762.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr19_+_17970693 0.34 ENST00000600147.1
ENST00000599898.1
RPL18A
ribosomal protein L18a
chr19_-_1592652 0.34 ENST00000156825.1
ENST00000434436.3
MBD3
methyl-CpG binding domain protein 3
chr6_+_26020672 0.33 ENST00000357647.3
HIST1H3A
histone cluster 1, H3a
chr5_-_176889381 0.32 ENST00000393563.4
ENST00000512501.1
DBN1
drebrin 1
chr17_-_34257731 0.32 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RDM1
RAD52 motif 1
chr6_+_80129989 0.32 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr11_-_62323702 0.31 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr6_-_26124138 0.31 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr8_+_27169138 0.30 ENST00000522338.1
PTK2B
protein tyrosine kinase 2 beta
chr11_+_64685026 0.30 ENST00000526559.1
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr16_-_31076332 0.30 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668
zinc finger protein 668
chr16_+_83986827 0.30 ENST00000393306.1
ENST00000565123.1
OSGIN1
oxidative stress induced growth inhibitor 1
chr19_+_17970677 0.30 ENST00000222247.5
RPL18A
ribosomal protein L18a
chr9_+_97766469 0.30 ENST00000433691.2
C9orf3
chromosome 9 open reading frame 3
chr3_-_48732926 0.29 ENST00000453202.1
IP6K2
inositol hexakisphosphate kinase 2
chr16_+_3068393 0.29 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr4_-_70626314 0.29 ENST00000510821.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr11_-_9482010 0.28 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr17_+_42422629 0.27 ENST00000589536.1
ENST00000587109.1
ENST00000587518.1
GRN
granulin
chr12_+_113354341 0.27 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr11_+_65337901 0.27 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
SSSCA1
Sjogren syndrome/scleroderma autoantigen 1
chr3_+_52489503 0.27 ENST00000345716.4
NISCH
nischarin
chr19_+_17830051 0.27 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
MAP1S
microtubule-associated protein 1S
chr19_-_42931567 0.26 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr6_+_26217159 0.25 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr21_-_46964306 0.25 ENST00000443742.1
ENST00000528477.1
ENST00000567670.1
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr17_-_76836963 0.25 ENST00000312010.6
USP36
ubiquitin specific peptidase 36
chrX_+_153237740 0.23 ENST00000369982.4
TMEM187
transmembrane protein 187
chr8_+_30300119 0.23 ENST00000520191.1
RBPMS
RNA binding protein with multiple splicing
chr11_+_67798090 0.23 ENST00000313468.5
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr17_-_39661947 0.22 ENST00000590425.1
KRT13
keratin 13
chr17_-_29645836 0.22 ENST00000578584.1
CTD-2370N5.3
CTD-2370N5.3
chr1_-_32169761 0.22 ENST00000271069.6
COL16A1
collagen, type XVI, alpha 1
chr11_-_64536521 0.22 ENST00000486867.1
SF1
splicing factor 1
chr16_-_3068171 0.22 ENST00000572154.1
ENST00000328796.4
CLDN6
claudin 6
chrX_-_153236819 0.21 ENST00000354233.3
HCFC1
host cell factor C1 (VP16-accessory protein)
chr19_-_11266437 0.21 ENST00000586708.1
ENST00000591396.1
ENST00000592967.1
ENST00000585486.1
ENST00000585567.1
SPC24
SPC24, NDC80 kinetochore complex component
chr17_+_42422637 0.21 ENST00000053867.3
ENST00000588143.1
GRN
granulin
chr14_+_23654525 0.21 ENST00000399910.1
ENST00000492621.1
C14orf164
chromosome 14 open reading frame 164
chr11_+_67798114 0.21 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr1_-_32169920 0.21 ENST00000373672.3
ENST00000373668.3
COL16A1
collagen, type XVI, alpha 1
chr3_-_10334617 0.20 ENST00000429122.1
ENST00000425479.1
ENST00000335542.8
GHRL
ghrelin/obestatin prepropeptide
chr19_+_16308711 0.20 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr17_+_38334501 0.20 ENST00000541245.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr3_+_124223586 0.20 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr1_+_161475208 0.20 ENST00000367972.4
ENST00000271450.6
FCGR2A
Fc fragment of IgG, low affinity IIa, receptor (CD32)
chr3_-_39196049 0.20 ENST00000514182.1
CSRNP1
cysteine-serine-rich nuclear protein 1
chr15_+_77713222 0.19 ENST00000558176.1
HMG20A
high mobility group 20A
chr19_-_44174305 0.19 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr19_-_11266471 0.19 ENST00000592540.1
SPC24
SPC24, NDC80 kinetochore complex component
chr16_+_33204156 0.19 ENST00000398667.4
TP53TG3C
TP53 target 3C
chr2_-_36779411 0.19 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr17_+_42422662 0.19 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN
granulin
chr6_-_160210692 0.18 ENST00000538128.1
ENST00000537390.1
TCP1
t-complex 1
chr19_+_17186577 0.18 ENST00000595618.1
ENST00000594824.1
MYO9B
myosin IXB
chr1_-_6445809 0.18 ENST00000377855.2
ACOT7
acyl-CoA thioesterase 7
chr17_-_36884451 0.17 ENST00000595377.1
AC006449.1
NS5ATP13TP1; Uncharacterized protein
chr10_+_18629628 0.17 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr11_+_101983176 0.17 ENST00000524575.1
YAP1
Yes-associated protein 1
chr15_-_93353028 0.17 ENST00000557398.2
FAM174B
family with sequence similarity 174, member B
chr4_-_76928641 0.17 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chrX_-_153237258 0.17 ENST00000310441.7
HCFC1
host cell factor C1 (VP16-accessory protein)
chr1_-_48866517 0.17 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr14_-_47812321 0.17 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr6_-_144416737 0.17 ENST00000367569.2
SF3B5
splicing factor 3b, subunit 5, 10kDa
chr20_+_2821340 0.17 ENST00000380445.3
ENST00000380469.3
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr11_+_114168085 0.16 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase
chr4_-_105416039 0.16 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr11_+_67798363 0.16 ENST00000525628.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr10_+_32735030 0.16 ENST00000277657.6
ENST00000362006.5
CCDC7
coiled-coil domain containing 7
chr3_-_10334585 0.16 ENST00000430179.1
ENST00000449238.2
ENST00000437422.2
ENST00000287656.7
ENST00000457360.1
ENST00000439975.2
ENST00000446937.2
GHRL
ghrelin/obestatin prepropeptide
chr22_+_18632666 0.16 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr12_+_110011571 0.16 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr15_+_44084040 0.15 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr16_-_3074231 0.15 ENST00000572355.1
ENST00000248089.3
ENST00000574980.1
ENST00000354679.3
ENST00000396916.1
ENST00000573842.1
HCFC1R1
host cell factor C1 regulator 1 (XPO1 dependent)
chr11_+_7506713 0.14 ENST00000329293.3
ENST00000534244.1
OLFML1
olfactomedin-like 1
chr19_+_10362882 0.14 ENST00000393733.2
ENST00000588502.1
MRPL4
mitochondrial ribosomal protein L4
chr16_-_31076273 0.14 ENST00000426488.2
ZNF668
zinc finger protein 668
chr15_-_79576156 0.14 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
RP11-17L5.4
RP11-17L5.4
chr19_+_16308659 0.14 ENST00000590263.1
ENST00000590756.1
ENST00000541844.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr10_-_99185798 0.14 ENST00000439965.2
AL355490.1
LOC644215 protein; Uncharacterized protein
chr19_-_5719860 0.13 ENST00000590729.1
LONP1
lon peptidase 1, mitochondrial
chr17_-_295730 0.13 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr12_-_53298841 0.13 ENST00000293308.6
KRT8
keratin 8
chr14_-_39417410 0.13 ENST00000557019.1
ENST00000556116.1
ENST00000554732.1
LINC00639
long intergenic non-protein coding RNA 639
chr10_+_46994087 0.13 ENST00000374317.1
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr14_+_95078714 0.13 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr17_-_29624343 0.13 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr5_-_139937895 0.13 ENST00000336283.6
SRA1
steroid receptor RNA activator 1
chrX_-_51797351 0.13 ENST00000375644.3
RP11-114H20.1
RP11-114H20.1
chr4_+_108746282 0.13 ENST00000503862.1
SGMS2
sphingomyelin synthase 2
chr3_-_48632593 0.13 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr5_-_1799864 0.12 ENST00000510999.1
MRPL36
mitochondrial ribosomal protein L36
chr20_-_2821271 0.12 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr10_+_135204338 0.12 ENST00000468317.2
RP11-108K14.8
Mitochondrial GTPase 1
chr7_-_33080506 0.12 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr12_-_111926342 0.12 ENST00000389154.3
ATXN2
ataxin 2
chr11_+_9482551 0.12 ENST00000438144.2
ENST00000526657.1
ENST00000299606.2
ENST00000534265.1
ENST00000412390.2
ZNF143
zinc finger protein 143
chr11_+_94277017 0.12 ENST00000358752.2
FUT4
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr9_+_132565454 0.11 ENST00000427860.1
TOR1B
torsin family 1, member B (torsin B)
chr6_-_31648150 0.11 ENST00000375858.3
ENST00000383237.4
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr18_-_67623906 0.11 ENST00000583955.1
CD226
CD226 molecule
chr19_-_15544099 0.11 ENST00000599910.2
WIZ
widely interspaced zinc finger motifs
chr14_-_65409438 0.11 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr20_-_2821756 0.11 ENST00000356872.3
ENST00000439542.1
PCED1A
PC-esterase domain containing 1A
chr11_-_46639436 0.11 ENST00000532281.1
HARBI1
harbinger transposase derived 1
chr1_-_153085984 0.11 ENST00000468739.1
SPRR2F
small proline-rich protein 2F
chr1_-_208417620 0.11 ENST00000367033.3
PLXNA2
plexin A2
chr4_-_1685718 0.10 ENST00000472884.2
ENST00000489363.1
ENST00000308132.6
ENST00000463238.1
FAM53A
family with sequence similarity 53, member A
chr13_+_50570019 0.10 ENST00000442421.1
TRIM13
tripartite motif containing 13
chr15_-_79576229 0.10 ENST00000557790.1
ENST00000558297.1
RP11-17L5.4
RP11-17L5.4
chr14_-_65409502 0.10 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr1_-_153931052 0.10 ENST00000368630.3
ENST00000368633.1
CRTC2
CREB regulated transcription coactivator 2
chr10_-_4720301 0.10 ENST00000449712.1
LINC00704
long intergenic non-protein coding RNA 704
chrX_-_153637612 0.10 ENST00000369807.1
ENST00000369808.3
DNASE1L1
deoxyribonuclease I-like 1
chr14_+_74551650 0.10 ENST00000554938.1
LIN52
lin-52 homolog (C. elegans)
chr4_+_76481258 0.10 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr12_-_118628315 0.09 ENST00000540561.1
TAOK3
TAO kinase 3
chr14_-_74551096 0.09 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr17_-_39661849 0.09 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chrX_-_132231123 0.09 ENST00000511190.1
USP26
ubiquitin specific peptidase 26
chr6_+_108616054 0.09 ENST00000368977.4
LACE1
lactation elevated 1
chr19_-_55791563 0.09 ENST00000588971.1
ENST00000255631.5
ENST00000587551.1
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr16_+_32264040 0.09 ENST00000398664.3
TP53TG3D
TP53 target 3D
chr14_-_23388338 0.09 ENST00000555209.1
ENST00000554256.1
ENST00000557403.1
ENST00000557549.1
ENST00000555676.1
ENST00000557571.1
ENST00000557464.1
ENST00000554618.1
ENST00000556862.1
ENST00000555722.1
ENST00000346528.5
ENST00000542016.2
ENST00000399922.2
ENST00000557227.1
ENST00000359890.3
RBM23
RNA binding motif protein 23
chr17_-_7307358 0.09 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr16_+_57406437 0.08 ENST00000564948.1
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr17_+_48610074 0.08 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chr8_-_38034192 0.08 ENST00000520755.1
LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_-_59951112 0.08 ENST00000247194.4
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr14_+_67656110 0.08 ENST00000524532.1
ENST00000530728.1
FAM71D
family with sequence similarity 71, member D
chr9_+_116263639 0.08 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr3_+_98482175 0.08 ENST00000485391.1
ENST00000492254.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr11_+_64073022 0.08 ENST00000406310.1
ENST00000000442.6
ENST00000539594.1
ESRRA
estrogen-related receptor alpha
chr19_-_55791431 0.08 ENST00000593263.1
ENST00000376343.3
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr3_+_39509163 0.08 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chr22_+_44427230 0.07 ENST00000444029.1
PARVB
parvin, beta
chr8_+_27168988 0.07 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr6_-_33285505 0.07 ENST00000431845.2
ZBTB22
zinc finger and BTB domain containing 22
chr5_-_1799965 0.07 ENST00000508987.1
MRPL36
mitochondrial ribosomal protein L36
chr16_-_69373396 0.07 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chrX_-_31285018 0.07 ENST00000361471.4
DMD
dystrophin
chr9_+_134065506 0.07 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr19_+_58193388 0.07 ENST00000596085.1
ENST00000594684.1
ZNF551
AC003006.7
zinc finger protein 551
Uncharacterized protein
chr16_-_32688053 0.07 ENST00000398682.4
TP53TG3
TP53 target 3
chr3_+_139062838 0.07 ENST00000310776.4
ENST00000465056.1
ENST00000465373.1
MRPS22
mitochondrial ribosomal protein S22
chr19_+_37341260 0.07 ENST00000589046.1
ZNF345
zinc finger protein 345
chr18_-_67629015 0.07 ENST00000579496.1
CD226
CD226 molecule
chr19_-_55791540 0.07 ENST00000433386.2
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr6_-_144385698 0.07 ENST00000444202.1
ENST00000437412.1
PLAGL1
pleiomorphic adenoma gene-like 1
chr11_-_118901559 0.07 ENST00000330775.7
ENST00000545985.1
ENST00000357590.5
ENST00000538950.1
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr15_+_99645277 0.07 ENST00000336292.6
ENST00000328642.7
SYNM
synemin, intermediate filament protein
chr3_+_39509070 0.06 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr3_+_154801678 0.06 ENST00000462837.1
MME
membrane metallo-endopeptidase
chr17_+_45973516 0.06 ENST00000376741.4
SP2
Sp2 transcription factor
chr7_+_100303676 0.06 ENST00000303151.4
POP7
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr2_-_27545921 0.06 ENST00000402310.1
ENST00000405983.1
ENST00000403262.2
ENST00000428910.1
ENST00000402722.1
ENST00000399052.4
ENST00000380044.1
ENST00000405076.1
MPV17
MpV17 mitochondrial inner membrane protein
chr3_+_26735991 0.06 ENST00000456208.2
LRRC3B
leucine rich repeat containing 3B
chrX_-_31285042 0.06 ENST00000378680.2
ENST00000378723.3
DMD
dystrophin
chr17_+_41150290 0.06 ENST00000589037.1
ENST00000253788.5
RPL27
ribosomal protein L27
chr11_-_61687739 0.06 ENST00000531922.1
ENST00000301773.5
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr15_-_50558223 0.06 ENST00000267845.3
HDC
histidine decarboxylase
chr19_+_52704346 0.06 ENST00000462990.1
PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr5_-_160279207 0.06 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr13_+_111893533 0.06 ENST00000478679.1
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr4_-_10118469 0.06 ENST00000499869.2
WDR1
WD repeat domain 1
chr6_-_127780510 0.06 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr12_+_4829507 0.06 ENST00000252318.2
GALNT8
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)
chr15_+_85147127 0.06 ENST00000541040.1
ENST00000538076.1
ENST00000485222.2
ZSCAN2
zinc finger and SCAN domain containing 2
chr14_+_61449197 0.06 ENST00000533744.2
SLC38A6
solute carrier family 38, member 6
chr5_+_140723601 0.06 ENST00000253812.6
PCDHGA3
protocadherin gamma subfamily A, 3
chr8_-_101157680 0.06 ENST00000428847.2
FBXO43
F-box protein 43
chr20_-_34330129 0.05 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RBM39
RNA binding motif protein 39
chr14_+_91709103 0.05 ENST00000553725.1
CTD-2547L24.3
HCG1816139; Uncharacterized protein
chr5_+_176873446 0.05 ENST00000507881.1
PRR7
proline rich 7 (synaptic)
chr8_-_93029865 0.05 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_71791726 0.05 ENST00000393695.3
NUMA1
nuclear mitotic apparatus protein 1
chr15_+_57540230 0.05 ENST00000559703.1
TCF12
transcription factor 12
chr16_-_21436459 0.05 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0046010 positive regulation of growth rate(GO:0040010) negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.4 GO:0019046 release from viral latency(GO:0019046)
0.1 0.6 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.4 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.2 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.3 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.0 0.2 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.1 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 1.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.3 GO:0048243 norepinephrine secretion(GO:0048243)
0.0 0.3 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.5 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.4 GO:0033622 integrin activation(GO:0033622)
0.0 0.3 GO:0048757 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.2 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.0 GO:0044417 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.5 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016608 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.6 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.3 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0070364 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.4 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 1.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade