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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NKX3-2

Z-value: 0.66

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Transcription factors associated with NKX3-2

Gene Symbol Gene ID Gene Info
NKX3-2
ENSG00000109705.7 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX3-2hg19_v2_chr4_-_13546632_135466740.295.8e-01Click!

Activity profile of NKX3-2 motif

Sorted Z-values of NKX3-2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_18544045 0.41 ENST00000599699.2
SSBP4
single stranded DNA binding protein 4
chr2_-_25451065 0.37 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr3_-_100551141 0.33 ENST00000478235.1
ENST00000471901.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr15_-_40401062 0.32 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF
Bcl2 modifying factor
chrX_+_38420623 0.26 ENST00000378482.2
TSPAN7
tetraspanin 7
chrY_+_15418467 0.26 ENST00000595988.1
AC010877.1
Uncharacterized protein
chr4_-_85771168 0.25 ENST00000514071.1
WDFY3
WD repeat and FYVE domain containing 3
chr15_-_100258029 0.24 ENST00000378904.2
DKFZP779J2370
DKFZP779J2370
chr3_-_42003613 0.24 ENST00000414606.1
ULK4
unc-51 like kinase 4
chr8_+_86999516 0.23 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr19_+_41497178 0.23 ENST00000324071.4
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr6_+_80129989 0.21 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr10_-_98031310 0.20 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr1_+_164528437 0.20 ENST00000485769.1
PBX1
pre-B-cell leukemia homeobox 1
chr8_+_22414182 0.19 ENST00000524057.1
SORBS3
sorbin and SH3 domain containing 3
chr14_+_23016437 0.19 ENST00000478163.3
TRAC
T cell receptor alpha constant
chr7_-_120498357 0.18 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr19_+_54609230 0.18 ENST00000420296.1
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr8_+_87111059 0.18 ENST00000285393.3
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr12_+_96337061 0.18 ENST00000266736.2
AMDHD1
amidohydrolase domain containing 1
chr6_-_30899924 0.18 ENST00000359086.3
SFTA2
surfactant associated 2
chr2_+_74229812 0.17 ENST00000305799.7
TET3
tet methylcytosine dioxygenase 3
chr2_+_145780767 0.17 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr1_-_161337662 0.17 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr12_+_6309517 0.17 ENST00000382519.4
ENST00000009180.4
CD9
CD9 molecule
chr19_+_16999654 0.17 ENST00000248076.3
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr3_-_52008016 0.17 ENST00000489595.2
ENST00000461108.1
ENST00000395008.2
ENST00000525795.1
ENST00000361143.5
RP11-155D18.14
ABHD14B
Poly(rC)-binding protein 4
abhydrolase domain containing 14B
chr9_+_97562440 0.17 ENST00000395357.2
C9orf3
chromosome 9 open reading frame 3
chr7_-_117512264 0.16 ENST00000454375.1
CTTNBP2
cortactin binding protein 2
chr15_-_79576156 0.16 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
RP11-17L5.4
RP11-17L5.4
chr19_-_44809121 0.16 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
ZNF235
zinc finger protein 235
chr19_-_36545649 0.15 ENST00000292894.1
THAP8
THAP domain containing 8
chr4_-_168155577 0.15 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr12_-_113658892 0.15 ENST00000299732.2
ENST00000416617.2
IQCD
IQ motif containing D
chr12_+_6309963 0.15 ENST00000382515.2
CD9
CD9 molecule
chr6_-_4347271 0.14 ENST00000437430.2
RP3-527G5.1
RP3-527G5.1
chr1_+_162351503 0.14 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr12_-_95397442 0.13 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr14_+_50779029 0.13 ENST00000245448.6
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr2_+_17721920 0.13 ENST00000295156.4
VSNL1
visinin-like 1
chr7_-_24957699 0.12 ENST00000441059.1
ENST00000415162.1
OSBPL3
oxysterol binding protein-like 3
chrX_+_105936982 0.12 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr7_-_38969150 0.12 ENST00000418457.2
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr14_+_21566980 0.12 ENST00000418511.2
ENST00000554329.2
TMEM253
transmembrane protein 253
chr11_-_72852958 0.12 ENST00000458644.2
FCHSD2
FCH and double SH3 domains 2
chr16_+_57406437 0.12 ENST00000564948.1
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr11_+_62432777 0.12 ENST00000532971.1
METTL12
methyltransferase like 12
chr10_+_96305535 0.11 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
HELLS
helicase, lymphoid-specific
chr2_+_62132781 0.11 ENST00000311832.5
COMMD1
copper metabolism (Murr1) domain containing 1
chrX_+_38420783 0.11 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr1_+_149230680 0.11 ENST00000443018.1
RP11-403I13.5
RP11-403I13.5
chr2_-_175869936 0.11 ENST00000409900.3
CHN1
chimerin 1
chr8_-_27469383 0.11 ENST00000519742.1
CLU
clusterin
chr5_+_40909354 0.11 ENST00000313164.9
C7
complement component 7
chr11_-_118047376 0.10 ENST00000278947.5
SCN2B
sodium channel, voltage-gated, type II, beta subunit
chr12_+_34175398 0.10 ENST00000538927.1
ALG10
ALG10, alpha-1,2-glucosyltransferase
chr11_-_59633951 0.10 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr4_-_141348789 0.10 ENST00000414773.1
CLGN
calmegin
chr17_+_4835580 0.10 ENST00000329125.5
GP1BA
glycoprotein Ib (platelet), alpha polypeptide
chr15_+_84841242 0.10 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr5_+_127039075 0.10 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr1_+_10509971 0.10 ENST00000320498.4
CORT
cortistatin
chr6_+_155443048 0.09 ENST00000535583.1
TIAM2
T-cell lymphoma invasion and metastasis 2
chr12_-_21927736 0.09 ENST00000240662.2
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr1_+_26517052 0.09 ENST00000338855.2
ENST00000456354.2
CATSPER4
cation channel, sperm associated 4
chr14_-_50778931 0.09 ENST00000555423.1
ENST00000421284.3
L2HGDH
L-2-hydroxyglutarate dehydrogenase
chr4_+_26324474 0.09 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr22_-_21356375 0.09 ENST00000215742.4
ENST00000399133.2
THAP7
THAP domain containing 7
chr11_+_93474786 0.09 ENST00000331239.4
ENST00000533585.1
ENST00000528099.1
ENST00000354421.3
ENST00000540113.1
ENST00000530620.1
ENST00000527003.1
ENST00000531650.1
ENST00000530279.1
C11orf54
chromosome 11 open reading frame 54
chr4_-_141348999 0.09 ENST00000325617.5
CLGN
calmegin
chr12_+_50794947 0.09 ENST00000552445.1
LARP4
La ribonucleoprotein domain family, member 4
chr5_-_137514333 0.09 ENST00000411594.2
ENST00000430331.1
BRD8
bromodomain containing 8
chr19_-_17185848 0.09 ENST00000593360.1
HAUS8
HAUS augmin-like complex, subunit 8
chr5_+_118406796 0.08 ENST00000503802.1
DMXL1
Dmx-like 1
chr17_+_58755184 0.08 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr6_-_30080876 0.08 ENST00000376734.3
TRIM31
tripartite motif containing 31
chr19_-_51412584 0.08 ENST00000431178.2
KLK4
kallikrein-related peptidase 4
chr2_+_208104497 0.08 ENST00000430494.1
AC007879.7
AC007879.7
chr2_+_238395042 0.08 ENST00000429898.1
ENST00000410032.1
MLPH
melanophilin
chr15_+_42694573 0.08 ENST00000397200.4
ENST00000569827.1
CAPN3
calpain 3, (p94)
chr2_+_25016282 0.08 ENST00000260662.1
CENPO
centromere protein O
chr1_+_119957554 0.08 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr14_+_50779071 0.08 ENST00000426751.2
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr5_-_149669612 0.08 ENST00000510347.1
CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr1_+_162601774 0.08 ENST00000415555.1
DDR2
discoidin domain receptor tyrosine kinase 2
chr1_+_95583479 0.08 ENST00000455656.1
ENST00000604534.1
TMEM56
RP11-57H12.6
transmembrane protein 56
TMEM56-RWDD3 readthrough
chr11_-_22851367 0.08 ENST00000354193.4
SVIP
small VCP/p97-interacting protein
chr3_-_100558953 0.08 ENST00000533795.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr12_+_71833756 0.08 ENST00000536515.1
ENST00000540815.2
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr17_+_76126842 0.08 ENST00000590426.1
ENST00000590799.1
ENST00000318430.5
ENST00000589691.1
TMC8
transmembrane channel-like 8
chr1_-_2461684 0.08 ENST00000378453.3
HES5
hes family bHLH transcription factor 5
chr16_+_5121814 0.08 ENST00000262374.5
ENST00000586840.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr12_-_120765565 0.08 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr17_+_4854375 0.08 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
ENO3
enolase 3 (beta, muscle)
chr9_-_131940526 0.08 ENST00000372491.2
IER5L
immediate early response 5-like
chr16_-_5083589 0.07 ENST00000563578.1
ENST00000562346.2
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr12_+_56473939 0.07 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_+_112162381 0.07 ENST00000433097.1
ENST00000369709.3
ENST00000436150.2
RAP1A
RAP1A, member of RAS oncogene family
chr19_-_51920952 0.07 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr3_+_51977294 0.07 ENST00000498510.1
PARP3
poly (ADP-ribose) polymerase family, member 3
chr12_-_113658826 0.07 ENST00000546692.1
IQCD
IQ motif containing D
chr6_-_32557610 0.07 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr4_+_159727222 0.07 ENST00000512986.1
FNIP2
folliculin interacting protein 2
chr20_-_634000 0.07 ENST00000381962.3
SRXN1
sulfiredoxin 1
chr15_-_63450192 0.07 ENST00000411926.1
RPS27L
ribosomal protein S27-like
chr15_+_89402148 0.07 ENST00000560601.1
ACAN
aggrecan
chr20_+_1115821 0.07 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr22_-_41636929 0.07 ENST00000216241.9
CHADL
chondroadherin-like
chr16_+_69333585 0.07 ENST00000570054.2
RP11-343C2.11
Uncharacterized protein
chr21_+_33671160 0.07 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr9_-_112970436 0.07 ENST00000400613.4
C9orf152
chromosome 9 open reading frame 152
chr20_+_54987305 0.07 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr17_+_7482785 0.07 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68
CD68 molecule
chr12_-_21928515 0.07 ENST00000537950.1
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr5_-_137514288 0.07 ENST00000454473.1
ENST00000418329.1
ENST00000455658.2
ENST00000230901.5
ENST00000402931.1
BRD8
bromodomain containing 8
chr1_+_86889769 0.07 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr8_+_70404996 0.07 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr9_-_74979420 0.07 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr10_-_7708918 0.06 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr20_+_42839722 0.06 ENST00000442383.1
ENST00000435163.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr14_+_64565442 0.06 ENST00000553308.1
SYNE2
spectrin repeat containing, nuclear envelope 2
chrX_+_105937068 0.06 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr14_+_31494672 0.06 ENST00000542754.2
ENST00000313566.6
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr2_-_175870085 0.06 ENST00000409156.3
CHN1
chimerin 1
chr21_-_33984865 0.06 ENST00000458138.1
C21orf59
chromosome 21 open reading frame 59
chr15_-_85259360 0.06 ENST00000559729.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chr10_-_98031265 0.06 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr12_-_68845165 0.06 ENST00000360485.3
ENST00000441255.2
RP11-81H14.2
RP11-81H14.2
chr12_+_56473910 0.06 ENST00000411731.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr9_+_131062367 0.06 ENST00000601297.1
AL359091.2
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr3_+_50192457 0.06 ENST00000414301.1
ENST00000450338.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr19_-_51920873 0.06 ENST00000441969.3
ENST00000525998.1
ENST00000436984.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr7_-_56160666 0.06 ENST00000297373.2
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr10_+_35415719 0.06 ENST00000474362.1
ENST00000374721.3
CREM
cAMP responsive element modulator
chr2_+_44396000 0.06 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr19_+_52074502 0.06 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
ZNF175
zinc finger protein 175
chr1_-_155145721 0.06 ENST00000295682.4
KRTCAP2
keratinocyte associated protein 2
chr3_+_177545563 0.06 ENST00000434309.1
RP11-91K9.1
RP11-91K9.1
chr3_-_48481518 0.06 ENST00000412398.2
ENST00000395696.1
CCDC51
coiled-coil domain containing 51
chr7_-_128415844 0.06 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr6_+_159084188 0.06 ENST00000367081.3
SYTL3
synaptotagmin-like 3
chr10_+_101089107 0.06 ENST00000446890.1
ENST00000370528.3
CNNM1
cyclin M1
chr15_-_83474806 0.06 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr19_+_16435625 0.05 ENST00000248071.5
ENST00000592003.1
KLF2
Kruppel-like factor 2
chr12_-_68845417 0.05 ENST00000542875.1
RP11-81H14.2
RP11-81H14.2
chr12_+_32687221 0.05 ENST00000525053.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr4_-_11430221 0.05 ENST00000514690.1
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr17_-_40168698 0.05 ENST00000590774.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chrX_-_119445306 0.05 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
TMEM255A
transmembrane protein 255A
chr7_-_111424462 0.05 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr19_+_57999101 0.05 ENST00000347466.6
ENST00000523138.1
ENST00000415379.2
ENST00000521754.1
ENST00000221735.7
ENST00000518999.1
ENST00000521137.1
ZNF419
zinc finger protein 419
chr1_-_160040038 0.05 ENST00000368089.3
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr4_+_159727272 0.05 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr10_-_27529779 0.05 ENST00000426079.1
ACBD5
acyl-CoA binding domain containing 5
chr4_+_169575875 0.05 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr17_-_42908155 0.05 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1
gap junction protein, gamma 1, 45kDa
chr4_+_156680518 0.05 ENST00000513437.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr3_+_125694347 0.05 ENST00000505382.1
ENST00000511082.1
ROPN1B
rhophilin associated tail protein 1B
chr7_+_30174574 0.05 ENST00000409688.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr4_+_37245799 0.05 ENST00000309447.5
KIAA1239
KIAA1239
chr7_-_14026123 0.05 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr12_-_57037284 0.05 ENST00000551570.1
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr19_-_51920835 0.05 ENST00000442846.3
ENST00000530476.1
SIGLEC10
sialic acid binding Ig-like lectin 10
chr3_-_112693865 0.05 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200R1
CD200 receptor 1
chr2_+_201754050 0.05 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr2_-_45166338 0.05 ENST00000437916.2
RP11-89K21.1
RP11-89K21.1
chr5_+_78407602 0.05 ENST00000274353.5
ENST00000524080.1
BHMT
betaine--homocysteine S-methyltransferase
chr9_+_124329336 0.05 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr15_+_88120158 0.05 ENST00000560153.1
LINC00052
long intergenic non-protein coding RNA 52
chr4_+_156588115 0.05 ENST00000455639.2
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr3_-_146262293 0.05 ENST00000448205.1
PLSCR1
phospholipid scramblase 1
chr6_+_18155560 0.05 ENST00000546309.2
ENST00000388870.2
ENST00000397244.1
KDM1B
lysine (K)-specific demethylase 1B
chr5_-_160279207 0.05 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr6_+_5261730 0.05 ENST00000274680.4
FARS2
phenylalanyl-tRNA synthetase 2, mitochondrial
chr20_-_2821271 0.05 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr5_-_77072085 0.05 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
TBCA
tubulin folding cofactor A
chr20_+_33462745 0.05 ENST00000488172.1
ACSS2
acyl-CoA synthetase short-chain family member 2
chr9_-_23821842 0.05 ENST00000544538.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr7_-_102119342 0.05 ENST00000393794.3
ENST00000292614.5
POLR2J
polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr9_+_19049372 0.05 ENST00000380527.1
RRAGA
Ras-related GTP binding A
chr6_+_31082603 0.05 ENST00000259881.9
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr15_+_81475047 0.05 ENST00000559388.1
IL16
interleukin 16
chr2_+_145780739 0.05 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
TEX41
testis expressed 41 (non-protein coding)
chr3_+_111697843 0.04 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
ABHD10
abhydrolase domain containing 10
chr17_+_43238438 0.04 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr5_+_68711209 0.04 ENST00000512803.1
MARVELD2
MARVEL domain containing 2
chr11_-_76381029 0.04 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr4_-_84205905 0.04 ENST00000311461.7
ENST00000311469.4
ENST00000439031.2
COQ2
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
chr12_+_104982622 0.04 ENST00000549016.1
CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr2_-_27294500 0.04 ENST00000447619.1
ENST00000429985.1
ENST00000456793.1
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr8_+_145162629 0.04 ENST00000323662.8
KIAA1875
KIAA1875
chr17_-_1619568 0.04 ENST00000571595.1
MIR22HG
MIR22 host gene (non-protein coding)
chr8_-_144674284 0.04 ENST00000528519.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr11_-_119993979 0.04 ENST00000524816.3
ENST00000525327.1
TRIM29
tripartite motif containing 29
chrX_+_44732757 0.04 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A
lysine (K)-specific demethylase 6A
chr1_+_31769836 0.04 ENST00000344147.5
ENST00000373714.1
ENST00000546109.1
ENST00000422613.2
ZCCHC17
zinc finger, CCHC domain containing 17
chr17_+_53828432 0.04 ENST00000573500.1
PCTP
phosphatidylcholine transfer protein
chr14_-_90798418 0.04 ENST00000354366.3
NRDE2
NRDE-2, necessary for RNA interference, domain containing
chr5_+_150051149 0.04 ENST00000523553.1
MYOZ3
myozenin 3
chr9_+_109694914 0.04 ENST00000542028.1
ZNF462
zinc finger protein 462

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.0 0.2 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.3 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.4 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.1 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.0 0.1 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.4 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.0 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.0 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.0 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.5 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:2000301 response to antineoplastic agent(GO:0097327) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.0 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.1 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.0 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.0 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.2 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.0 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.0 GO:0031433 telethonin binding(GO:0031433)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins