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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for NKX6-3
Z-value: 0.25
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Transcription factors associated with NKX6-3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
NKX6-3
|
ENSG00000165066.11 | NK6 homeobox 3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NKX6-3 | hg19_v2_chr8_-_41508855_41508855 | -0.72 | 1.0e-01 | Click! |
Activity profile of NKX6-3 motif
Sorted Z-values of NKX6-3 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_90769422 | 0.15 |
ENST00000524190.1
ENST00000523859.1 |
RP11-37B2.1
|
RP11-37B2.1 |
| chr5_-_139726181 | 0.12 |
ENST00000507104.1
ENST00000230990.6 |
HBEGF
|
heparin-binding EGF-like growth factor |
| chr3_+_138340067 | 0.09 |
ENST00000479848.1
|
FAIM
|
Fas apoptotic inhibitory molecule |
| chr14_-_51027838 | 0.09 |
ENST00000555216.1
|
MAP4K5
|
mitogen-activated protein kinase kinase kinase kinase 5 |
| chr17_+_4692230 | 0.08 |
ENST00000331264.7
|
GLTPD2
|
glycolipid transfer protein domain containing 2 |
| chr2_-_44550441 | 0.08 |
ENST00000420756.1
ENST00000444696.1 |
PREPL
|
prolyl endopeptidase-like |
| chr18_+_32558380 | 0.07 |
ENST00000588349.2
|
MAPRE2
|
microtubule-associated protein, RP/EB family, member 2 |
| chr9_+_125133315 | 0.06 |
ENST00000223423.4
ENST00000362012.2 |
PTGS1
|
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| chrX_+_43515467 | 0.06 |
ENST00000338702.3
ENST00000542639.1 |
MAOA
|
monoamine oxidase A |
| chr9_+_125133467 | 0.06 |
ENST00000426608.1
|
PTGS1
|
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| chr14_+_67831576 | 0.05 |
ENST00000555876.1
|
EIF2S1
|
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa |
| chr3_+_136649311 | 0.05 |
ENST00000469404.1
ENST00000467911.1 |
NCK1
|
NCK adaptor protein 1 |
| chr4_+_80584903 | 0.04 |
ENST00000506460.1
|
RP11-452C8.1
|
RP11-452C8.1 |
| chr3_+_138340049 | 0.04 |
ENST00000464668.1
|
FAIM
|
Fas apoptotic inhibitory molecule |
| chr6_+_114178512 | 0.03 |
ENST00000368635.4
|
MARCKS
|
myristoylated alanine-rich protein kinase C substrate |
| chr15_+_90735145 | 0.03 |
ENST00000559792.1
|
SEMA4B
|
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B |
| chrX_+_107288239 | 0.03 |
ENST00000217957.5
|
VSIG1
|
V-set and immunoglobulin domain containing 1 |
| chr14_+_88852059 | 0.02 |
ENST00000045347.7
|
SPATA7
|
spermatogenesis associated 7 |
| chr20_-_33735070 | 0.02 |
ENST00000374491.3
ENST00000542871.1 ENST00000374492.3 |
EDEM2
|
ER degradation enhancer, mannosidase alpha-like 2 |
| chrX_+_107288197 | 0.02 |
ENST00000415430.3
|
VSIG1
|
V-set and immunoglobulin domain containing 1 |
| chr9_+_125132803 | 0.02 |
ENST00000540753.1
|
PTGS1
|
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| chr1_-_232651312 | 0.02 |
ENST00000262861.4
|
SIPA1L2
|
signal-induced proliferation-associated 1 like 2 |
| chr5_-_58295712 | 0.02 |
ENST00000317118.8
|
PDE4D
|
phosphodiesterase 4D, cAMP-specific |
| chr15_+_48051920 | 0.02 |
ENST00000559196.1
|
SEMA6D
|
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| chr8_+_92261516 | 0.02 |
ENST00000276609.3
ENST00000309536.2 |
SLC26A7
|
solute carrier family 26 (anion exchanger), member 7 |
| chr9_-_215744 | 0.02 |
ENST00000382387.2
|
C9orf66
|
chromosome 9 open reading frame 66 |
| chr4_+_71384300 | 0.02 |
ENST00000504451.1
|
AMTN
|
amelotin |
| chr10_-_27529486 | 0.01 |
ENST00000375888.1
|
ACBD5
|
acyl-CoA binding domain containing 5 |
| chr13_-_81801115 | 0.01 |
ENST00000567258.1
|
LINC00564
|
long intergenic non-protein coding RNA 564 |
| chrX_+_47696275 | 0.01 |
ENST00000376954.1
ENST00000338637.7 |
ZNF81
|
zinc finger protein 81 |
| chr5_-_142780280 | 0.01 |
ENST00000424646.2
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| chr12_-_94673956 | 0.01 |
ENST00000551941.1
|
RP11-1105G2.3
|
Uncharacterized protein |
| chr18_+_20494078 | 0.01 |
ENST00000579124.1
ENST00000577588.1 ENST00000582354.1 ENST00000581819.1 |
RBBP8
|
retinoblastoma binding protein 8 |
| chr8_+_77593474 | 0.01 |
ENST00000455469.2
ENST00000050961.6 |
ZFHX4
|
zinc finger homeobox 4 |
| chr15_+_93443419 | 0.01 |
ENST00000557381.1
ENST00000420239.2 |
CHD2
|
chromodomain helicase DNA binding protein 2 |
| chrX_+_107288280 | 0.00 |
ENST00000458383.1
|
VSIG1
|
V-set and immunoglobulin domain containing 1 |
| chr3_+_121902511 | 0.00 |
ENST00000490131.1
|
CASR
|
calcium-sensing receptor |
| chr11_+_22689648 | 0.00 |
ENST00000278187.3
|
GAS2
|
growth arrest-specific 2 |
| chr19_-_6057282 | 0.00 |
ENST00000592281.1
|
RFX2
|
regulatory factor X, 2 (influences HLA class II expression) |
| chrX_-_110655306 | 0.00 |
ENST00000371993.2
|
DCX
|
doublecortin |
Network of associatons between targets according to the STRING database.
First level regulatory network of NKX6-3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0051541 | elastin metabolic process(GO:0051541) |
| 0.0 | 0.0 | GO:1903676 | regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676) |
| 0.0 | 0.1 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0043614 | multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |