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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NOTO_VSX2_DLX2_DLX6_NKX6-1

Z-value: 0.49

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Transcription factors associated with NOTO_VSX2_DLX2_DLX6_NKX6-1

Gene Symbol Gene ID Gene Info
NOTO
ENSG00000214513.3 notochord homeobox
VSX2
ENSG00000119614.2 visual system homeobox 2
DLX2
ENSG00000115844.6 distal-less homeobox 2
DLX6
ENSG00000006377.9 distal-less homeobox 6
NKX6-1
ENSG00000163623.5 NK6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DLX6hg19_v2_chr7_+_96634850_966348740.216.9e-01Click!
NOTOhg19_v2_chr2_+_73429386_734293860.177.4e-01Click!
DLX2hg19_v2_chr2_-_172967621_1729676370.019.9e-01Click!

Activity profile of NOTO_VSX2_DLX2_DLX6_NKX6-1 motif

Sorted Z-values of NOTO_VSX2_DLX2_DLX6_NKX6-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_25281747 0.72 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr17_+_47448102 0.34 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr6_+_130339710 0.34 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr21_+_17909594 0.33 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chr17_-_38928414 0.32 ENST00000335552.4
KRT26
keratin 26
chr5_+_53751445 0.31 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr8_-_72268721 0.28 ENST00000419131.1
ENST00000388743.2
EYA1
eyes absent homolog 1 (Drosophila)
chr5_+_36606700 0.26 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_+_105235572 0.25 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr4_+_71108300 0.22 ENST00000304954.3
CSN3
casein kappa
chr14_-_92413727 0.22 ENST00000267620.10
FBLN5
fibulin 5
chr3_-_141747950 0.22 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr6_-_39693111 0.22 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6
kinesin family member 6
chr14_-_57197224 0.21 ENST00000554597.1
ENST00000556696.1
RP11-1085N6.3
Uncharacterized protein
chr5_-_56778635 0.21 ENST00000423391.1
ACTBL2
actin, beta-like 2
chr17_-_39123144 0.21 ENST00000355612.2
KRT39
keratin 39
chr4_+_105828537 0.20 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr4_+_105828492 0.19 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr13_+_36050881 0.18 ENST00000537702.1
NBEA
neurobeachin
chr2_+_66918558 0.18 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chrX_-_133792480 0.18 ENST00000359237.4
PLAC1
placenta-specific 1
chr20_-_50418972 0.18 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr21_+_17443521 0.17 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr4_-_184243561 0.17 ENST00000514470.1
ENST00000541814.1
CLDN24
claudin 24
chr21_-_31538971 0.16 ENST00000286808.3
CLDN17
claudin 17
chr17_+_59489112 0.16 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr8_-_72268889 0.16 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr7_-_111424462 0.15 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr13_-_36050819 0.15 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr20_-_50418947 0.15 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr4_+_26324474 0.15 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr13_-_41593425 0.14 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr15_+_93443419 0.14 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr5_-_88119580 0.12 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr11_+_35222629 0.12 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr11_+_115498761 0.12 ENST00000424313.2
AP000997.1
AP000997.1
chr21_+_17443434 0.12 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr4_-_140544386 0.12 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr5_-_126409159 0.11 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr11_-_129062093 0.11 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr12_-_28122980 0.11 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr5_-_24645078 0.11 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr9_-_75488984 0.11 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
RP11-151D14.1
chrM_+_7586 0.11 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr4_-_138453606 0.11 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr14_+_61654271 0.11 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr1_+_68150744 0.11 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr6_+_155538093 0.11 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr14_+_59100774 0.10 ENST00000556859.1
ENST00000421793.1
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr17_-_38911580 0.10 ENST00000312150.4
KRT25
keratin 25
chr6_-_31107127 0.10 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr10_+_123951957 0.10 ENST00000514539.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr6_+_139135648 0.10 ENST00000541398.1
ECT2L
epithelial cell transforming sequence 2 oncogene-like
chr7_+_66800928 0.10 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr12_-_28123206 0.10 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr3_-_131756559 0.10 ENST00000505957.1
CPNE4
copine IV
chr1_+_160160283 0.09 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr3_+_173116225 0.09 ENST00000457714.1
NLGN1
neuroligin 1
chr8_-_72268968 0.09 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr17_-_39623681 0.09 ENST00000225899.3
KRT32
keratin 32
chr1_+_160160346 0.09 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr5_-_96478466 0.09 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr11_-_16419067 0.09 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr17_-_2117600 0.09 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr11_-_8290263 0.09 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr12_+_54378849 0.09 ENST00000515593.1
HOXC10
homeobox C10
chr2_-_214017151 0.09 ENST00000452786.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr1_-_150738261 0.08 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr17_+_18086392 0.08 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr5_+_140625147 0.08 ENST00000231173.3
PCDHB15
protocadherin beta 15
chr4_+_71384257 0.08 ENST00000339336.4
AMTN
amelotin
chr2_+_47454054 0.08 ENST00000426892.1
AC106869.2
AC106869.2
chr13_-_36788718 0.08 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr8_-_10512569 0.08 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr4_-_186696425 0.08 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr5_-_88120083 0.08 ENST00000509373.1
MEF2C
myocyte enhancer factor 2C
chr10_+_118083919 0.08 ENST00000333254.3
CCDC172
coiled-coil domain containing 172
chr12_+_54378923 0.08 ENST00000303460.4
HOXC10
homeobox C10
chr1_+_225600404 0.08 ENST00000366845.2
AC092811.1
AC092811.1
chr19_-_12889226 0.08 ENST00000589400.1
ENST00000590839.1
ENST00000592079.1
HOOK2
hook microtubule-tethering protein 2
chr1_-_92952433 0.08 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr7_+_99717230 0.08 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr20_+_52105495 0.08 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr2_+_190541153 0.08 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chrM_+_10758 0.07 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr3_-_71777824 0.07 ENST00000469524.1
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr3_+_111718173 0.07 ENST00000494932.1
TAGLN3
transgelin 3
chr1_+_183774285 0.07 ENST00000539189.1
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr4_-_89442940 0.07 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr21_+_17792672 0.07 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr7_-_14028488 0.07 ENST00000405358.4
ETV1
ets variant 1
chr1_-_68698222 0.07 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr3_-_126327398 0.07 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr5_+_147582387 0.07 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr20_-_60294804 0.07 ENST00000317652.1
RP11-429E11.3
Uncharacterized protein
chr17_+_43238438 0.07 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chrX_+_68835911 0.07 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chr9_+_82188077 0.07 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr18_-_53089723 0.07 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr1_-_68698197 0.07 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr20_-_50419055 0.07 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr5_+_60933634 0.07 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr14_-_36988882 0.07 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr15_+_67841330 0.07 ENST00000354498.5
MAP2K5
mitogen-activated protein kinase kinase 5
chr6_-_33160231 0.06 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr5_-_124082279 0.06 ENST00000513986.1
ZNF608
zinc finger protein 608
chr19_-_7698599 0.06 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr17_-_78450398 0.06 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr13_-_31040060 0.06 ENST00000326004.4
ENST00000341423.5
HMGB1
high mobility group box 1
chr15_+_76352178 0.06 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr17_-_39203519 0.06 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chrX_-_46187069 0.06 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr2_-_182545603 0.06 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr12_-_6233828 0.06 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr1_+_61548374 0.06 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
NFIA
nuclear factor I/A
chr7_+_139528952 0.06 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr14_+_72052983 0.06 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr15_+_67390920 0.06 ENST00000559092.1
ENST00000560175.1
SMAD3
SMAD family member 3
chr3_-_178984759 0.06 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr12_-_30887948 0.06 ENST00000433722.2
CAPRIN2
caprin family member 2
chr6_+_4087664 0.06 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chrX_-_64196351 0.06 ENST00000374839.3
ZC4H2
zinc finger, C4H2 domain containing
chr1_-_45956868 0.06 ENST00000451835.2
TESK2
testis-specific kinase 2
chr7_-_14026123 0.06 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr13_-_95131923 0.06 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chrM_-_14670 0.06 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr10_+_24755416 0.06 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr20_+_42187682 0.05 ENST00000373092.3
ENST00000373077.1
SGK2
serum/glucocorticoid regulated kinase 2
chrX_-_73512358 0.05 ENST00000602776.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chrX_+_13671225 0.05 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr2_-_224467093 0.05 ENST00000305409.2
SCG2
secretogranin II
chr12_-_16760021 0.05 ENST00000540445.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_159557637 0.05 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr14_-_21994337 0.05 ENST00000537235.1
ENST00000450879.2
SALL2
spalt-like transcription factor 2
chr4_+_169418255 0.05 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr17_+_72931876 0.05 ENST00000328801.4
OTOP3
otopetrin 3
chr14_-_92413353 0.05 ENST00000556154.1
FBLN5
fibulin 5
chr9_+_82267508 0.05 ENST00000490347.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr15_-_37393406 0.05 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr2_-_203735586 0.05 ENST00000454326.1
ENST00000432273.1
ENST00000450143.1
ENST00000411681.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr6_-_30899924 0.05 ENST00000359086.3
SFTA2
surfactant associated 2
chr6_-_26235206 0.05 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr1_-_9953295 0.05 ENST00000377258.1
CTNNBIP1
catenin, beta interacting protein 1
chr5_-_20575959 0.05 ENST00000507958.1
CDH18
cadherin 18, type 2
chr1_-_152131703 0.05 ENST00000316073.3
RPTN
repetin
chr16_+_24621546 0.05 ENST00000566108.1
CTD-2540M10.1
CTD-2540M10.1
chr6_+_5261225 0.05 ENST00000324331.6
FARS2
phenylalanyl-tRNA synthetase 2, mitochondrial
chr17_-_39140549 0.05 ENST00000377755.4
KRT40
keratin 40
chr4_-_177116772 0.05 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr12_-_54653313 0.05 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr10_+_4828815 0.05 ENST00000533295.1
AKR1E2
aldo-keto reductase family 1, member E2
chr7_-_111032971 0.05 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr7_-_130080977 0.05 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr2_-_227050079 0.05 ENST00000423838.1
AC068138.1
AC068138.1
chrM_+_14741 0.05 ENST00000361789.2
MT-CYB
mitochondrially encoded cytochrome b
chr2_-_40680578 0.05 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr10_-_96829246 0.05 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr8_-_101661887 0.05 ENST00000311812.2
SNX31
sorting nexin 31
chr12_-_15114658 0.05 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr17_-_40337470 0.05 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr4_-_186696561 0.05 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr20_+_56136136 0.05 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr6_-_5261141 0.05 ENST00000330636.4
ENST00000500576.2
LYRM4
LYR motif containing 4
chr12_+_25205628 0.05 ENST00000554942.1
LRMP
lymphoid-restricted membrane protein
chr16_+_69345243 0.05 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chrM_+_10464 0.05 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr5_+_31193847 0.05 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr17_-_61045902 0.05 ENST00000581596.1
RP11-180P8.3
RP11-180P8.3
chrX_-_106243451 0.05 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr11_+_34663913 0.04 ENST00000532302.1
EHF
ets homologous factor
chr7_-_14029515 0.04 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr11_-_107729287 0.04 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr7_-_14026063 0.04 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr15_+_45544426 0.04 ENST00000347644.3
ENST00000560438.1
SLC28A2
solute carrier family 28 (concentrative nucleoside transporter), member 2
chr11_-_124981475 0.04 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218
transmembrane protein 218
chrX_+_100224676 0.04 ENST00000450049.2
ARL13A
ADP-ribosylation factor-like 13A
chr6_+_148593425 0.04 ENST00000367469.1
SASH1
SAM and SH3 domain containing 1
chr12_-_56321397 0.04 ENST00000557259.1
ENST00000549939.1
WIBG
within bgcn homolog (Drosophila)
chr3_-_101039402 0.04 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr3_+_156799587 0.04 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr12_+_25205155 0.04 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr12_-_53994805 0.04 ENST00000328463.7
ATF7
activating transcription factor 7
chr3_+_15045419 0.04 ENST00000406272.2
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr3_-_120400960 0.04 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr1_+_214161272 0.04 ENST00000498508.2
ENST00000366958.4
PROX1
prospero homeobox 1
chrM_+_3299 0.04 ENST00000361390.2
MT-ND1
mitochondrially encoded NADH dehydrogenase 1
chr2_-_70780770 0.04 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr6_-_123958051 0.04 ENST00000546248.1
TRDN
triadin
chr9_+_44867571 0.04 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chr1_+_168250194 0.04 ENST00000367821.3
TBX19
T-box 19
chr17_+_48243352 0.04 ENST00000344627.6
ENST00000262018.3
ENST00000543315.1
ENST00000451235.2
ENST00000511303.1
SGCA
sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
chr6_-_111136299 0.04 ENST00000457688.1
CDK19
cyclin-dependent kinase 19
chr3_-_114173530 0.04 ENST00000470311.1
ZBTB20
zinc finger and BTB domain containing 20
chr17_+_46970127 0.04 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr17_+_46970134 0.04 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr7_-_84121858 0.04 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr20_+_58630972 0.04 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr5_+_147582348 0.04 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr6_+_151646800 0.04 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr8_-_72274095 0.04 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of NOTO_VSX2_DLX2_DLX6_NKX6-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990637 response to prolactin(GO:1990637)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.0 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.2 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.1 GO:2000979 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) negative regulation of bile acid biosynthetic process(GO:0070858) acinar cell differentiation(GO:0090425) negative regulation of bile acid metabolic process(GO:1904252) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.1 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.0 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.0 GO:1904640 response to methionine(GO:1904640)
0.0 0.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.0 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.0 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.0 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.1 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.0 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors