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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR2E3

Z-value: 0.92

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Transcription factors associated with NR2E3

Gene Symbol Gene ID Gene Info
NR2E3
ENSG00000031544.10 nuclear receptor subfamily 2 group E member 3

Activity profile of NR2E3 motif

Sorted Z-values of NR2E3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_148593425 0.50 ENST00000367469.1
SASH1
SAM and SH3 domain containing 1
chr14_-_31926623 0.50 ENST00000356180.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr2_+_145780767 0.48 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr11_-_914774 0.46 ENST00000528154.1
ENST00000525840.1
CHID1
chitinase domain containing 1
chr3_-_195310802 0.40 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr4_-_23891693 0.39 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr5_+_59783941 0.35 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr5_+_102200948 0.35 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chrX_-_106959631 0.32 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr4_-_186732892 0.32 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2
sorbin and SH3 domain containing 2
chr15_-_41120896 0.32 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr3_+_69915363 0.31 ENST00000451708.1
MITF
microphthalmia-associated transcription factor
chr10_-_91403625 0.29 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
PANK1
pantothenate kinase 1
chr6_+_74405501 0.29 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr11_+_121447469 0.29 ENST00000532694.1
ENST00000534286.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr3_+_181429704 0.28 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr1_+_164528866 0.28 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr14_+_54976603 0.28 ENST00000557317.1
CGRRF1
cell growth regulator with ring finger domain 1
chr1_+_149858461 0.27 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr14_+_62462541 0.27 ENST00000430451.2
SYT16
synaptotagmin XVI
chr4_+_174089904 0.27 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr12_+_56661461 0.27 ENST00000546544.1
ENST00000553234.1
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr11_-_108408895 0.26 ENST00000443411.1
ENST00000533052.1
EXPH5
exophilin 5
chr19_+_2977444 0.26 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr6_+_27215494 0.25 ENST00000230582.3
PRSS16
protease, serine, 16 (thymus)
chrX_-_117119243 0.25 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr6_+_27215471 0.25 ENST00000421826.2
PRSS16
protease, serine, 16 (thymus)
chr16_+_86612112 0.25 ENST00000320241.3
FOXL1
forkhead box L1
chr19_-_40596767 0.25 ENST00000599972.1
ENST00000450241.2
ENST00000595687.2
ZNF780A
zinc finger protein 780A
chr1_+_164529004 0.24 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1
pre-B-cell leukemia homeobox 1
chr12_+_41221975 0.24 ENST00000552913.1
CNTN1
contactin 1
chr15_+_42697065 0.24 ENST00000565559.1
CAPN3
calpain 3, (p94)
chr2_+_190722119 0.24 ENST00000452382.1
PMS1
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
chr4_+_160188306 0.24 ENST00000510510.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr15_+_75640068 0.24 ENST00000565051.1
ENST00000564257.1
ENST00000567005.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr3_+_69915385 0.24 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr2_-_178128250 0.23 ENST00000448782.1
ENST00000446151.2
NFE2L2
nuclear factor, erythroid 2-like 2
chr6_-_33679452 0.23 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
UQCC2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr5_+_138210919 0.23 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr11_-_47600549 0.23 ENST00000430070.2
KBTBD4
kelch repeat and BTB (POZ) domain containing 4
chr19_-_46706186 0.23 ENST00000601263.1
ENST00000598754.1
ENST00000594027.1
ENST00000598518.1
ENST00000599817.1
ENST00000595673.1
AC006262.5
AC006262.5
chr8_+_74903580 0.23 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr3_-_196159268 0.22 ENST00000381887.3
ENST00000535858.1
ENST00000428095.1
ENST00000296328.4
UBXN7
UBX domain protein 7
chrX_+_123097014 0.22 ENST00000394478.1
STAG2
stromal antigen 2
chr1_+_89829610 0.22 ENST00000370456.4
ENST00000535065.1
GBP6
guanylate binding protein family, member 6
chr7_-_124569864 0.22 ENST00000609702.1
POT1
protection of telomeres 1
chr20_-_14318248 0.22 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr4_+_71859156 0.22 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
DCK
deoxycytidine kinase
chr4_+_174089951 0.22 ENST00000512285.1
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr14_+_31494672 0.22 ENST00000542754.2
ENST00000313566.6
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr13_+_51913819 0.21 ENST00000419898.2
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr22_-_40929812 0.21 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr8_+_67579807 0.21 ENST00000519289.1
ENST00000519561.1
ENST00000521889.1
C8orf44-SGK3
C8orf44
C8orf44-SGK3 readthrough
chromosome 8 open reading frame 44
chr9_+_72658490 0.21 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr6_+_45296391 0.21 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr5_-_124084493 0.20 ENST00000509799.1
ZNF608
zinc finger protein 608
chr7_-_124569991 0.20 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
POT1
protection of telomeres 1
chr4_-_88312301 0.20 ENST00000507286.1
HSD17B11
hydroxysteroid (17-beta) dehydrogenase 11
chr1_+_84630053 0.20 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_102962874 0.20 ENST00000531543.1
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5
chr20_-_20033052 0.20 ENST00000536226.1
CRNKL1
crooked neck pre-mRNA splicing factor 1
chr13_-_86373536 0.20 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chrX_-_102565858 0.20 ENST00000449185.1
ENST00000536889.1
BEX2
brain expressed X-linked 2
chr5_+_96079240 0.20 ENST00000515663.1
CAST
calpastatin
chr2_+_171036635 0.20 ENST00000484338.2
ENST00000334231.6
MYO3B
myosin IIIB
chr15_+_45879964 0.19 ENST00000565409.1
ENST00000564765.1
BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr2_-_207082748 0.19 ENST00000407325.2
ENST00000411719.1
GPR1
G protein-coupled receptor 1
chr1_-_47131521 0.19 ENST00000542495.1
ENST00000532925.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr1_+_62439037 0.19 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr18_-_28622699 0.19 ENST00000360428.4
DSC3
desmocollin 3
chr13_+_49822041 0.19 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
CDADC1
cytidine and dCMP deaminase domain containing 1
chr5_-_160365601 0.18 ENST00000518580.1
ENST00000518301.1
RP11-109J4.1
RP11-109J4.1
chr10_-_98031265 0.18 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr2_+_172309634 0.18 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr10_-_93392811 0.18 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr2_-_197675000 0.18 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr11_+_122709200 0.18 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr3_-_185826718 0.18 ENST00000413301.1
ENST00000421809.1
ETV5
ets variant 5
chr3_-_165555200 0.18 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr19_+_50148087 0.18 ENST00000601038.1
ENST00000595242.1
SCAF1
SR-related CTD-associated factor 1
chr1_-_144995074 0.18 ENST00000534536.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr19_+_17337473 0.18 ENST00000598068.1
OCEL1
occludin/ELL domain containing 1
chr12_+_53443963 0.18 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr14_-_54908043 0.17 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr2_-_207082624 0.17 ENST00000458440.1
ENST00000437420.1
GPR1
G protein-coupled receptor 1
chr18_-_28622774 0.17 ENST00000434452.1
DSC3
desmocollin 3
chr20_-_40247002 0.17 ENST00000373222.3
CHD6
chromodomain helicase DNA binding protein 6
chr12_-_15815626 0.17 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr3_+_186501979 0.17 ENST00000498746.1
EIF4A2
eukaryotic translation initiation factor 4A2
chr4_-_170947565 0.17 ENST00000506764.1
MFAP3L
microfibrillar-associated protein 3-like
chr11_+_1891380 0.17 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
LSP1
lymphocyte-specific protein 1
chr7_-_84121858 0.17 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_-_158732340 0.17 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1
activin A receptor, type I
chr12_+_32655110 0.17 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr5_+_59783540 0.17 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr12_+_41221794 0.17 ENST00000547849.1
CNTN1
contactin 1
chr9_+_72002837 0.16 ENST00000377216.3
FAM189A2
family with sequence similarity 189, member A2
chr12_+_56661033 0.16 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr6_-_113754604 0.16 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr1_+_234349957 0.16 ENST00000366617.3
SLC35F3
solute carrier family 35, member F3
chr10_-_61122220 0.16 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
FAM13C
family with sequence similarity 13, member C
chr8_-_95449155 0.16 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr3_-_169381183 0.15 ENST00000494292.1
MECOM
MDS1 and EVI1 complex locus
chr4_-_170948361 0.15 ENST00000393702.3
MFAP3L
microfibrillar-associated protein 3-like
chr4_-_153332886 0.15 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_+_47264711 0.15 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
CYP4B1
cytochrome P450, family 4, subfamily B, polypeptide 1
chr1_+_45140400 0.15 ENST00000453711.1
C1orf228
chromosome 1 open reading frame 228
chrX_+_119737806 0.15 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chrX_+_105412290 0.15 ENST00000357175.2
ENST00000337685.2
MUM1L1
melanoma associated antigen (mutated) 1-like 1
chr5_-_102455801 0.15 ENST00000508629.1
ENST00000399004.2
GIN1
gypsy retrotransposon integrase 1
chr1_-_146697185 0.15 ENST00000533174.1
ENST00000254090.4
FMO5
flavin containing monooxygenase 5
chr12_+_28605426 0.15 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chr19_-_40596828 0.15 ENST00000414720.2
ENST00000455521.1
ENST00000340963.5
ENST00000595773.1
ZNF780A
zinc finger protein 780A
chr6_-_75953484 0.15 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr2_+_149894968 0.15 ENST00000409642.3
LYPD6B
LY6/PLAUR domain containing 6B
chr17_+_57233087 0.15 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
PRR11
proline rich 11
chr15_-_33447055 0.14 ENST00000559047.1
ENST00000561249.1
FMN1
formin 1
chr3_-_195163584 0.14 ENST00000439666.1
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr1_+_203595689 0.14 ENST00000357681.5
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr4_-_129209221 0.14 ENST00000512483.1
PGRMC2
progesterone receptor membrane component 2
chr21_+_27543175 0.14 ENST00000608591.1
ENST00000609365.1
AP000230.1
AP000230.1
chr6_-_4135693 0.14 ENST00000495548.1
ENST00000380125.2
ENST00000465828.1
ECI2
enoyl-CoA delta isomerase 2
chr6_-_4135825 0.14 ENST00000380118.3
ENST00000413766.2
ENST00000361538.2
ECI2
enoyl-CoA delta isomerase 2
chr15_-_72565340 0.14 ENST00000568360.1
PARP6
poly (ADP-ribose) polymerase family, member 6
chr1_+_156084461 0.14 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
LMNA
lamin A/C
chr17_+_46185111 0.14 ENST00000582104.1
ENST00000584335.1
SNX11
sorting nexin 11
chr10_-_103603568 0.14 ENST00000356640.2
KCNIP2
Kv channel interacting protein 2
chr12_+_58138664 0.13 ENST00000257910.3
TSPAN31
tetraspanin 31
chr9_+_93759317 0.13 ENST00000563268.1
RP11-367F23.2
RP11-367F23.2
chr11_-_104905840 0.13 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr11_-_47600320 0.13 ENST00000525720.1
ENST00000531067.1
ENST00000533290.1
ENST00000529499.1
ENST00000529946.1
ENST00000526005.1
ENST00000395288.2
ENST00000534239.1
KBTBD4
kelch repeat and BTB (POZ) domain containing 4
chr2_-_178128149 0.13 ENST00000423513.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr12_+_32655048 0.13 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chrX_-_39956656 0.13 ENST00000397354.3
ENST00000378444.4
BCOR
BCL6 corepressor
chrX_-_135338503 0.13 ENST00000370663.5
MAP7D3
MAP7 domain containing 3
chr5_-_148930731 0.13 ENST00000515748.2
CSNK1A1
casein kinase 1, alpha 1
chr11_-_73471655 0.13 ENST00000400470.2
RAB6A
RAB6A, member RAS oncogene family
chr14_-_61124977 0.13 ENST00000554986.1
SIX1
SIX homeobox 1
chr12_-_57146095 0.13 ENST00000550770.1
ENST00000338193.6
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr1_+_24118452 0.13 ENST00000421070.1
LYPLA2
lysophospholipase II
chr20_-_40247133 0.13 ENST00000373233.3
ENST00000309279.7
CHD6
chromodomain helicase DNA binding protein 6
chr12_+_49740700 0.12 ENST00000549441.2
ENST00000395069.3
DNAJC22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr2_-_45795145 0.12 ENST00000535761.1
SRBD1
S1 RNA binding domain 1
chr15_+_23255242 0.12 ENST00000450802.3
GOLGA8I
golgin A8 family, member I
chr18_-_66382289 0.12 ENST00000443099.2
ENST00000562706.1
ENST00000544714.2
TMX3
thioredoxin-related transmembrane protein 3
chr11_+_111789580 0.12 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr11_-_82745238 0.12 ENST00000531021.1
RAB30
RAB30, member RAS oncogene family
chr14_-_37641618 0.12 ENST00000555449.1
SLC25A21
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr12_+_79258444 0.12 ENST00000261205.4
SYT1
synaptotagmin I
chr1_+_84629976 0.12 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr15_+_86087267 0.12 ENST00000558166.1
AKAP13
A kinase (PRKA) anchor protein 13
chr1_+_168250194 0.12 ENST00000367821.3
TBX19
T-box 19
chr2_-_197664366 0.12 ENST00000409364.3
ENST00000263956.3
GTF3C3
general transcription factor IIIC, polypeptide 3, 102kDa
chr5_+_179135246 0.12 ENST00000508787.1
CANX
calnexin
chr12_-_25150409 0.12 ENST00000549262.1
C12orf77
chromosome 12 open reading frame 77
chr14_+_56127989 0.12 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr15_-_38519066 0.11 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
RP11-346D14.1
chr4_-_156298087 0.11 ENST00000311277.4
MAP9
microtubule-associated protein 9
chrX_+_123094672 0.11 ENST00000354548.5
ENST00000458700.1
STAG2
stromal antigen 2
chr10_+_88428370 0.11 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3
LIM domain binding 3
chr2_+_160590469 0.11 ENST00000409591.1
MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr1_+_87797351 0.11 ENST00000370542.1
LMO4
LIM domain only 4
chr1_+_12042015 0.11 ENST00000412236.1
MFN2
mitofusin 2
chr13_+_60971080 0.11 ENST00000377894.2
TDRD3
tudor domain containing 3
chr10_-_16563870 0.11 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr11_+_17298543 0.11 ENST00000533926.1
NUCB2
nucleobindin 2
chr7_+_90339169 0.11 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr19_-_9546227 0.11 ENST00000361451.2
ENST00000361151.1
ZNF266
zinc finger protein 266
chr7_-_103848405 0.11 ENST00000447452.2
ENST00000545943.1
ENST00000297431.4
ORC5
origin recognition complex, subunit 5
chr15_-_77197620 0.11 ENST00000565970.1
ENST00000563290.1
ENST00000565372.1
ENST00000564177.1
ENST00000568382.1
ENST00000563919.1
SCAPER
S-phase cyclin A-associated protein in the ER
chr17_-_57232525 0.11 ENST00000583380.1
ENST00000580541.1
ENST00000578105.1
ENST00000437036.2
SKA2
spindle and kinetochore associated complex subunit 2
chrX_-_138914394 0.11 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATP11C
ATPase, class VI, type 11C
chr14_+_74035763 0.11 ENST00000238651.5
ACOT2
acyl-CoA thioesterase 2
chr3_-_69402828 0.10 ENST00000460709.1
FRMD4B
FERM domain containing 4B
chr12_+_48516463 0.10 ENST00000546465.1
PFKM
phosphofructokinase, muscle
chr1_-_229478714 0.10 ENST00000284617.2
CCSAP
centriole, cilia and spindle-associated protein
chr4_-_25865159 0.10 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr5_+_110559312 0.10 ENST00000508074.1
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr11_+_74204883 0.10 ENST00000528481.1
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chr1_+_84630645 0.10 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr15_-_50647347 0.10 ENST00000220429.8
ENST00000429662.2
GABPB1
GA binding protein transcription factor, beta subunit 1
chr21_-_16374688 0.10 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr2_+_130737223 0.10 ENST00000410061.2
RAB6C
RAB6C, member RAS oncogene family
chr4_+_159727272 0.10 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr12_+_32654965 0.10 ENST00000472289.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr11_+_63997750 0.10 ENST00000321685.3
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr1_-_144995002 0.10 ENST00000369356.4
PDE4DIP
phosphodiesterase 4D interacting protein
chr11_+_17298297 0.10 ENST00000529010.1
NUCB2
nucleobindin 2
chr1_+_167298281 0.10 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr17_-_57232596 0.10 ENST00000581068.1
ENST00000330137.7
SKA2
spindle and kinetochore associated complex subunit 2
chr18_+_23806382 0.10 ENST00000400466.2
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr19_-_9546177 0.10 ENST00000592292.1
ENST00000588221.1
ZNF266
zinc finger protein 266
chr5_-_138211051 0.10 ENST00000518785.1
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr2_+_73114489 0.10 ENST00000234454.5
SPR
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
chr6_-_42418999 0.10 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr7_+_94023873 0.10 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr12_-_76477707 0.09 ENST00000551992.1
NAP1L1
nucleosome assembly protein 1-like 1
chr16_+_21623392 0.09 ENST00000562961.1
METTL9
methyltransferase like 9
chr11_+_17298255 0.09 ENST00000531172.1
ENST00000533738.2
ENST00000323688.6
NUCB2
nucleobindin 2
chr11_+_17298522 0.09 ENST00000529313.1
NUCB2
nucleobindin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 0.3 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of mitochondrial DNA metabolic process(GO:1901860) response to methionine(GO:1904640)
0.1 0.7 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.4 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.4 GO:0018032 protein amidation(GO:0018032)
0.1 0.7 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.2 GO:1903249 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.1 0.5 GO:0097338 response to clozapine(GO:0097338)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.2 GO:0003274 endocardial cushion fusion(GO:0003274)
0.0 0.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.3 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.2 GO:0015888 thiamine transport(GO:0015888)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.2 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0030910 olfactory placode formation(GO:0030910) myotome development(GO:0061055) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.5 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.0 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:1901490 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) regulation of lymphangiogenesis(GO:1901490)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.2 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.0 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.0 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.0 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:1903412 response to bile acid(GO:1903412)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.0 GO:1904647 response to rotenone(GO:1904647)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0039713 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.4 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.2 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0055103 ligase regulator activity(GO:0055103)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.0 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.0 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB