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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR5A2

Z-value: 1.04

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Transcription factors associated with NR5A2

Gene Symbol Gene ID Gene Info
NR5A2
ENSG00000116833.9 nuclear receptor subfamily 5 group A member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR5A2hg19_v2_chr1_+_199996702_1999967320.246.4e-01Click!

Activity profile of NR5A2 motif

Sorted Z-values of NR5A2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_74864386 1.83 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr4_-_74904398 1.17 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr16_+_58535372 1.15 ENST00000566656.1
ENST00000566618.1
NDRG4
NDRG family member 4
chr14_+_21492331 0.99 ENST00000533984.1
ENST00000532213.2
AL161668.5
AL161668.5
chr6_+_27861190 0.91 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr5_-_150473127 0.83 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr6_+_43968306 0.82 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr11_+_118272328 0.79 ENST00000524422.1
ATP5L
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr13_-_30160925 0.75 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr19_+_45251804 0.74 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr14_-_24729251 0.72 ENST00000559136.1
TGM1
transglutaminase 1
chr12_-_7245125 0.62 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr11_-_105010320 0.61 ENST00000532895.1
ENST00000530950.1
CARD18
caspase recruitment domain family, member 18
chr17_+_46970134 0.61 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr4_-_74964904 0.60 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr6_+_31916733 0.59 ENST00000483004.1
CFB
complement factor B
chr8_-_125869733 0.59 ENST00000533496.1
RP11-1082L8.3
RP11-1082L8.3
chr4_+_74735102 0.57 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr6_-_72129806 0.57 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
LINC00472
long intergenic non-protein coding RNA 472
chr1_+_152881014 0.55 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr6_-_26250835 0.54 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr10_+_104180580 0.53 ENST00000425536.1
FBXL15
F-box and leucine-rich repeat protein 15
chr5_+_177540444 0.49 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chr22_-_30642782 0.49 ENST00000249075.3
LIF
leukemia inhibitory factor
chr12_-_7245018 0.48 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr12_+_56732658 0.47 ENST00000228534.4
IL23A
interleukin 23, alpha subunit p19
chr22_-_39636914 0.47 ENST00000381551.4
PDGFB
platelet-derived growth factor beta polypeptide
chr12_-_7245080 0.46 ENST00000541042.1
ENST00000540242.1
C1R
complement component 1, r subcomponent
chr14_-_31889737 0.44 ENST00000382464.2
HEATR5A
HEAT repeat containing 5A
chr12_+_122667658 0.39 ENST00000339777.4
ENST00000425921.1
LRRC43
leucine rich repeat containing 43
chr22_+_38382163 0.39 ENST00000333418.4
ENST00000427034.1
POLR2F
polymerase (RNA) II (DNA directed) polypeptide F
chr21_+_33671264 0.39 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr12_-_30907822 0.38 ENST00000540436.1
CAPRIN2
caprin family member 2
chr10_+_81107271 0.38 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr22_-_39637135 0.36 ENST00000440375.1
PDGFB
platelet-derived growth factor beta polypeptide
chr12_-_7245152 0.36 ENST00000542220.2
C1R
complement component 1, r subcomponent
chrX_+_109602039 0.36 ENST00000520821.1
RGAG1
retrotransposon gag domain containing 1
chr22_+_38071615 0.35 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr7_+_76107444 0.34 ENST00000435861.1
DTX2
deltex homolog 2 (Drosophila)
chr11_+_10472223 0.34 ENST00000396554.3
ENST00000524866.1
AMPD3
adenosine monophosphate deaminase 3
chr3_+_185046676 0.34 ENST00000428617.1
ENST00000443863.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr1_-_200992827 0.34 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr5_-_66942617 0.34 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr22_+_37959647 0.34 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr17_+_73455788 0.33 ENST00000581519.1
KIAA0195
KIAA0195
chr15_+_59730348 0.33 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr20_-_35329063 0.33 ENST00000422536.1
NDRG3
NDRG family member 3
chr22_+_38609538 0.32 ENST00000407965.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr19_+_45254529 0.32 ENST00000444487.1
BCL3
B-cell CLL/lymphoma 3
chr17_+_79670386 0.31 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
MRPL12
SLC25A10
SLC25A10
mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr16_-_57809015 0.31 ENST00000540079.2
ENST00000569222.1
KIFC3
kinesin family member C3
chr21_+_33671160 0.31 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr8_+_145149930 0.31 ENST00000318911.4
CYC1
cytochrome c-1
chr7_-_127671674 0.31 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr20_-_45280091 0.30 ENST00000396360.1
ENST00000435032.1
ENST00000413164.2
ENST00000372121.1
ENST00000339636.3
SLC13A3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr17_-_79792909 0.29 ENST00000330261.4
ENST00000570394.1
PPP1R27
protein phosphatase 1, regulatory subunit 27
chr10_+_102891048 0.29 ENST00000467928.2
TLX1
T-cell leukemia homeobox 1
chr13_-_111214015 0.29 ENST00000267328.3
RAB20
RAB20, member RAS oncogene family
chr16_+_67694849 0.29 ENST00000602551.1
ENST00000458121.2
ENST00000219255.3
PARD6A
par-6 family cell polarity regulator alpha
chr1_-_33502528 0.29 ENST00000354858.6
AK2
adenylate kinase 2
chr6_-_29648887 0.28 ENST00000376883.1
ZFP57
ZFP57 zinc finger protein
chr16_-_3767506 0.28 ENST00000538171.1
TRAP1
TNF receptor-associated protein 1
chr6_-_31939734 0.28 ENST00000375356.3
DXO
decapping exoribonuclease
chr8_-_100905925 0.28 ENST00000518171.1
COX6C
cytochrome c oxidase subunit VIc
chr16_-_3767551 0.27 ENST00000246957.5
TRAP1
TNF receptor-associated protein 1
chr17_-_6616678 0.27 ENST00000381074.4
ENST00000293800.6
ENST00000572352.1
ENST00000576323.1
ENST00000573648.1
SLC13A5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr2_-_220119280 0.27 ENST00000392088.2
TUBA4A
tubulin, alpha 4a
chr17_-_39928106 0.27 ENST00000540235.1
JUP
junction plakoglobin
chr4_-_85771168 0.27 ENST00000514071.1
WDFY3
WD repeat and FYVE domain containing 3
chr1_+_43613612 0.27 ENST00000335282.4
FAM183A
family with sequence similarity 183, member A
chr1_-_183559693 0.27 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr6_-_27100529 0.26 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ
histone cluster 1, H2bj
chr22_-_30814469 0.26 ENST00000598426.1
KIAA1658
KIAA1658
chr14_-_21491477 0.26 ENST00000298684.5
ENST00000557169.1
ENST00000553563.1
NDRG2
NDRG family member 2
chr11_+_67798114 0.25 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr17_+_46970127 0.25 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr12_+_51632666 0.25 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr1_-_2323140 0.25 ENST00000378531.3
ENST00000378529.3
MORN1
MORN repeat containing 1
chrX_-_104465358 0.25 ENST00000372578.3
ENST00000372575.1
ENST00000413579.1
TEX13A
testis expressed 13A
chr17_-_76778339 0.25 ENST00000591455.1
ENST00000446868.3
ENST00000361101.4
ENST00000589296.1
CYTH1
cytohesin 1
chr12_-_57039739 0.24 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr14_-_103989033 0.24 ENST00000553878.1
ENST00000557530.1
CKB
creatine kinase, brain
chr12_-_3862245 0.24 ENST00000252322.1
ENST00000440314.2
EFCAB4B
EF-hand calcium binding domain 4B
chr17_+_74536115 0.24 ENST00000592014.1
PRCD
progressive rod-cone degeneration
chrX_-_46618490 0.24 ENST00000328306.4
SLC9A7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr7_+_99156393 0.23 ENST00000422164.1
ENST00000422647.1
ENST00000427931.1
ZNF655
zinc finger protein 655
chr17_-_47925379 0.23 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr1_+_44444865 0.23 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr1_+_169077133 0.23 ENST00000494797.1
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr19_-_6057282 0.23 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr17_-_1553346 0.23 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr5_-_176056974 0.23 ENST00000510387.1
ENST00000506696.1
SNCB
synuclein, beta
chr22_+_30163340 0.22 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr1_+_161172143 0.22 ENST00000476409.2
NDUFS2
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr5_-_159766528 0.22 ENST00000505287.2
CCNJL
cyclin J-like
chr9_-_138391692 0.22 ENST00000429260.2
C9orf116
chromosome 9 open reading frame 116
chr10_-_75676400 0.22 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chrX_+_48681768 0.22 ENST00000430858.1
HDAC6
histone deacetylase 6
chr9_+_108424738 0.22 ENST00000334077.3
TAL2
T-cell acute lymphocytic leukemia 2
chr5_-_43412418 0.22 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chr1_+_1447517 0.22 ENST00000378756.3
ENST00000378755.5
ATAD3A
ATPase family, AAA domain containing 3A
chr14_-_21492251 0.22 ENST00000554398.1
NDRG2
NDRG family member 2
chr1_-_33502441 0.22 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
AK2
adenylate kinase 2
chrX_+_47083037 0.22 ENST00000523034.1
CDK16
cyclin-dependent kinase 16
chr9_+_132388566 0.21 ENST00000372480.1
NTMT1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr2_-_39187479 0.21 ENST00000601251.1
AC019171.1
Uncharacterized protein
chr8_-_10336885 0.21 ENST00000520494.1
RP11-981G7.3
RP11-981G7.3
chr17_-_46608272 0.21 ENST00000577092.1
ENST00000239174.6
HOXB1
homeobox B1
chr17_-_39093672 0.21 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr7_-_107883678 0.21 ENST00000417701.1
NRCAM
neuronal cell adhesion molecule
chr22_+_39348723 0.21 ENST00000402255.1
APOBEC3A
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
chr6_-_26235206 0.21 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr6_+_26199737 0.20 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr11_-_9025541 0.20 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
NRIP3
nuclear receptor interacting protein 3
chr15_-_81616446 0.20 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr18_+_42260059 0.20 ENST00000426838.4
SETBP1
SET binding protein 1
chr13_-_24476794 0.20 ENST00000382140.2
C1QTNF9B
C1q and tumor necrosis factor related protein 9B
chr10_-_112678692 0.20 ENST00000605742.1
BBIP1
BBSome interacting protein 1
chr6_+_32006042 0.20 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr5_+_71403061 0.20 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr19_-_13044494 0.20 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr3_-_169487617 0.20 ENST00000330368.2
ACTRT3
actin-related protein T3
chr19_+_46850320 0.20 ENST00000391919.1
PPP5C
protein phosphatase 5, catalytic subunit
chr12_+_42624050 0.20 ENST00000601185.1
AC020629.1
Uncharacterized protein
chr17_+_900342 0.20 ENST00000327158.4
TIMM22
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr1_-_12908578 0.19 ENST00000317869.6
HNRNPCL1
heterogeneous nuclear ribonucleoprotein C-like 1
chrX_-_55020511 0.19 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr8_+_145202939 0.19 ENST00000423230.2
ENST00000398656.4
MROH1
maestro heat-like repeat family member 1
chr6_+_32006159 0.19 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr19_-_7293942 0.19 ENST00000341500.5
ENST00000302850.5
INSR
insulin receptor
chr19_+_1407517 0.19 ENST00000336761.6
ENST00000233078.4
DAZAP1
DAZ associated protein 1
chr17_-_56591321 0.19 ENST00000583243.1
MTMR4
myotubularin related protein 4
chr5_+_71403280 0.19 ENST00000511641.2
MAP1B
microtubule-associated protein 1B
chr2_-_27718052 0.19 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr10_-_27529779 0.19 ENST00000426079.1
ACBD5
acyl-CoA binding domain containing 5
chr15_+_67420441 0.19 ENST00000558894.1
SMAD3
SMAD family member 3
chr1_-_27240455 0.19 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr19_+_46850251 0.18 ENST00000012443.4
PPP5C
protein phosphatase 5, catalytic subunit
chr11_+_126262027 0.18 ENST00000526311.1
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr1_+_161195781 0.18 ENST00000367988.3
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr19_+_41284121 0.18 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
RAB4B
RAB4B, member RAS oncogene family
chr20_-_48532019 0.18 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr3_-_121379739 0.18 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr2_-_31361543 0.18 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr11_-_65640071 0.18 ENST00000526624.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr5_-_74348371 0.18 ENST00000503568.1
RP11-229C3.2
RP11-229C3.2
chr7_+_44836276 0.18 ENST00000451562.1
ENST00000468812.1
ENST00000489459.1
ENST00000355968.6
PPIA
peptidylprolyl isomerase A (cyclophilin A)
chr13_+_22245522 0.18 ENST00000382353.5
FGF9
fibroblast growth factor 9
chr14_-_23504087 0.18 ENST00000493471.2
ENST00000460922.2
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr3_+_171844762 0.18 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr1_+_202995611 0.18 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr6_-_27860956 0.18 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr21_-_35288284 0.18 ENST00000290299.2
ATP5O
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr1_-_154600421 0.17 ENST00000368471.3
ENST00000292205.5
ADAR
adenosine deaminase, RNA-specific
chr17_+_48585794 0.17 ENST00000576179.1
ENST00000419930.1
MYCBPAP
MYCBP associated protein
chr9_-_130889990 0.17 ENST00000449878.1
PTGES2
prostaglandin E synthase 2
chr20_+_3776371 0.17 ENST00000245960.5
CDC25B
cell division cycle 25B
chr2_+_220492116 0.17 ENST00000373760.2
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr2_+_201994042 0.17 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr11_-_914812 0.17 ENST00000533059.1
CHID1
chitinase domain containing 1
chr8_-_100905850 0.17 ENST00000520271.1
ENST00000522940.1
ENST00000523016.1
ENST00000517682.2
ENST00000297564.2
COX6C
cytochrome c oxidase subunit VIc
chr9_+_131873842 0.17 ENST00000417728.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr7_+_48128854 0.17 ENST00000436673.1
ENST00000429491.2
UPP1
uridine phosphorylase 1
chr21_+_41029235 0.17 ENST00000380618.1
B3GALT5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr2_+_220491973 0.17 ENST00000358055.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr16_-_11363178 0.17 ENST00000312693.3
TNP2
transition protein 2 (during histone to protamine replacement)
chr11_+_73498973 0.17 ENST00000537007.1
MRPL48
mitochondrial ribosomal protein L48
chr22_-_32022280 0.17 ENST00000442379.1
PISD
phosphatidylserine decarboxylase
chr3_+_9851904 0.17 ENST00000547186.1
ENST00000397241.1
ENST00000426827.1
TTLL3
tubulin tyrosine ligase-like family, member 3
chr3_-_58643483 0.17 ENST00000483787.1
FAM3D
family with sequence similarity 3, member D
chr3_-_49941042 0.17 ENST00000344206.4
ENST00000296474.3
MST1R
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr9_+_33240157 0.17 ENST00000379721.3
SPINK4
serine peptidase inhibitor, Kazal type 4
chr14_-_105262016 0.17 ENST00000407796.2
AKT1
v-akt murine thymoma viral oncogene homolog 1
chr17_+_45727204 0.17 ENST00000290158.4
KPNB1
karyopherin (importin) beta 1
chr1_+_228270784 0.16 ENST00000541182.1
ARF1
ADP-ribosylation factor 1
chr20_+_3776936 0.16 ENST00000439880.2
CDC25B
cell division cycle 25B
chr3_-_14166316 0.16 ENST00000396914.3
ENST00000295767.5
CHCHD4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr15_+_78441663 0.16 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr17_+_46970178 0.16 ENST00000393366.2
ENST00000506855.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr19_-_2328572 0.16 ENST00000252622.10
LSM7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_-_105262055 0.16 ENST00000349310.3
AKT1
v-akt murine thymoma viral oncogene homolog 1
chr11_-_915012 0.16 ENST00000449825.1
ENST00000533056.1
CHID1
chitinase domain containing 1
chr15_+_73735490 0.16 ENST00000331090.6
ENST00000560581.1
C15orf60
chromosome 15 open reading frame 60
chrX_+_48620147 0.16 ENST00000303227.6
GLOD5
glyoxalase domain containing 5
chr11_-_65640198 0.16 ENST00000528176.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr2_+_120189422 0.16 ENST00000306406.4
TMEM37
transmembrane protein 37
chr17_-_46682321 0.16 ENST00000225648.3
ENST00000484302.2
HOXB6
homeobox B6
chr10_+_105156364 0.16 ENST00000369797.3
PDCD11
programmed cell death 11
chr9_+_103189660 0.16 ENST00000374886.3
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr17_+_30814707 0.16 ENST00000584792.1
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr17_+_40119801 0.16 ENST00000585452.1
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr19_+_13228917 0.16 ENST00000586171.1
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr7_+_48128816 0.16 ENST00000395564.4
UPP1
uridine phosphorylase 1
chr17_-_67323385 0.16 ENST00000588665.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr20_-_31989307 0.16 ENST00000473997.1
ENST00000544843.1
ENST00000346416.2
ENST00000357886.4
ENST00000339269.5
CDK5RAP1
CDK5 regulatory subunit associated protein 1
chr21_+_44073860 0.16 ENST00000335512.4
ENST00000539837.1
ENST00000291539.6
ENST00000380328.2
ENST00000398232.3
ENST00000398234.3
ENST00000398236.3
ENST00000328862.6
ENST00000335440.6
ENST00000398225.3
ENST00000398229.3
ENST00000398227.3
PDE9A
phosphodiesterase 9A
chr1_+_199996702 0.16 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr19_+_11201275 0.16 ENST00000252444.5
LDLR
low density lipoprotein receptor
chr11_-_3862059 0.15 ENST00000396978.1
RHOG
ras homolog family member G
chr16_+_89787393 0.15 ENST00000289816.5
ENST00000568064.1
ZNF276
zinc finger protein 276

Network of associatons between targets according to the STRING database.

First level regulatory network of NR5A2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.2 0.8 GO:1905174 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 4.6 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.2 1.1 GO:0015744 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.2 0.8 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.6 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.6 GO:0009386 translational attenuation(GO:0009386)
0.1 0.4 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.5 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.5 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.7 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.8 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.3 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 0.4 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 2.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.2 GO:0035570 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.1 0.2 GO:0021571 rhombomere 5 development(GO:0021571)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.2 GO:0036146 cellular response to mycotoxin(GO:0036146)
0.1 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.2 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.1 0.2 GO:0097187 dentinogenesis(GO:0097187)
0.1 0.2 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.2 GO:1902824 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.2 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.1 0.4 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.2 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.1 GO:0042938 positive regulation of cellular pH reduction(GO:0032849) dipeptide transport(GO:0042938)
0.0 0.5 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.0 0.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0021503 neural fold bending(GO:0021503)
0.0 0.6 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.0 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.1 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826)
0.0 0.1 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.6 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 1.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.1 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:0007343 egg activation(GO:0007343) female pronucleus assembly(GO:0035038)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.1 GO:0060926 cardiac pacemaker cell development(GO:0060926)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0018963 insecticide metabolic process(GO:0017143) phthalate metabolic process(GO:0018963) cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.3 GO:0007144 female meiosis I(GO:0007144)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:1904044 response to aldosterone(GO:1904044)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0009189 pyrimidine nucleoside diphosphate metabolic process(GO:0009138) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.4 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0070100 apoptotic process involved in luteolysis(GO:0061364) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.0 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.3 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.4 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.0 GO:1905033 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.0 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.3 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.0 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.0 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.0 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.5 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.3 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:1900107 embryonic hindgut morphogenesis(GO:0048619) regulation of nodal signaling pathway(GO:1900107)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:2000258 complement activation, lectin pathway(GO:0001867) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.2 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 1.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.3 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.3 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 0.3 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 0.2 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.4 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.4 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.6 GO:0005604 basement membrane(GO:0005604)
0.0 2.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.7 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2 1.1 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.2 0.5 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.4 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.6 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.4 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.3 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 2.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 1.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.3 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.2 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.6 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.0 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0015266 protein channel activity(GO:0015266)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.6 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995) PTB domain binding(GO:0051425)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.0 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.0 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.0 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.0 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 1.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.7 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 4.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport