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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for OLIG2_NEUROD1_ATOH1

Z-value: 0.96

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Transcription factors associated with OLIG2_NEUROD1_ATOH1

Gene Symbol Gene ID Gene Info
OLIG2
ENSG00000205927.4 oligodendrocyte transcription factor 2
NEUROD1
ENSG00000162992.3 neuronal differentiation 1
ATOH1
ENSG00000172238.3 atonal bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NEUROD1hg19_v2_chr2_-_182545603_182545603-0.786.5e-02Click!
OLIG2hg19_v2_chr21_+_34398153_34398250-0.118.4e-01Click!

Activity profile of OLIG2_NEUROD1_ATOH1 motif

Sorted Z-values of OLIG2_NEUROD1_ATOH1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_26250835 0.80 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr22_-_21905120 0.80 ENST00000331505.5
RIMBP3C
RIMS binding protein 3C
chr4_-_108204904 0.79 ENST00000510463.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr5_-_159766528 0.70 ENST00000505287.2
CCNJL
cyclin J-like
chr12_+_113416340 0.63 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr7_-_41742697 0.60 ENST00000242208.4
INHBA
inhibin, beta A
chr12_+_113416191 0.49 ENST00000342315.4
ENST00000392583.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr2_-_7005785 0.45 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr19_-_19030157 0.45 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
COPE
coatomer protein complex, subunit epsilon
chr12_-_13105081 0.43 ENST00000541128.1
GPRC5D
G protein-coupled receptor, family C, group 5, member D
chr16_-_69385681 0.42 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr6_+_53948328 0.41 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr12_+_122150646 0.40 ENST00000449592.2
TMEM120B
transmembrane protein 120B
chr7_-_150777920 0.40 ENST00000353841.2
ENST00000297532.6
FASTK
Fas-activated serine/threonine kinase
chr19_-_1650666 0.40 ENST00000588136.1
TCF3
transcription factor 3
chr19_+_19030478 0.39 ENST00000247003.4
DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr1_-_209792111 0.37 ENST00000455193.1
LAMB3
laminin, beta 3
chr14_-_75078725 0.37 ENST00000556690.1
LTBP2
latent transforming growth factor beta binding protein 2
chr2_-_220117867 0.36 ENST00000456818.1
ENST00000447205.1
TUBA4A
tubulin, alpha 4a
chr11_-_798239 0.35 ENST00000531437.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr7_-_44105158 0.34 ENST00000297283.3
PGAM2
phosphoglycerate mutase 2 (muscle)
chr9_+_19408919 0.34 ENST00000380376.1
ACER2
alkaline ceramidase 2
chr7_-_97881429 0.34 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
TECPR1
tectonin beta-propeller repeat containing 1
chr17_+_80193644 0.33 ENST00000582946.1
SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
chr1_-_63782888 0.33 ENST00000436475.2
LINC00466
long intergenic non-protein coding RNA 466
chr12_+_48152774 0.32 ENST00000549243.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr19_+_19030497 0.32 ENST00000438170.2
DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr7_-_150777949 0.31 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr9_+_131174024 0.30 ENST00000420034.1
ENST00000372842.1
CERCAM
cerebral endothelial cell adhesion molecule
chr2_-_27603582 0.29 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr13_-_33780133 0.29 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_+_53948221 0.28 ENST00000460844.2
MLIP
muscular LMNA-interacting protein
chr12_-_48152853 0.28 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr11_+_5775923 0.28 ENST00000317254.3
OR52N4
olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene)
chr3_-_65583561 0.27 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr15_+_89182156 0.27 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr16_+_67280799 0.26 ENST00000566345.2
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr19_-_6720686 0.26 ENST00000245907.6
C3
complement component 3
chr1_+_180897269 0.26 ENST00000367587.1
KIAA1614
KIAA1614
chr19_-_3772209 0.26 ENST00000555978.1
ENST00000555633.1
RAX2
retina and anterior neural fold homeobox 2
chrX_+_118108571 0.25 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr15_+_89182178 0.25 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_+_74723031 0.25 ENST00000586200.1
METTL23
methyltransferase like 23
chr11_-_1619524 0.25 ENST00000412090.1
KRTAP5-2
keratin associated protein 5-2
chr14_-_75079294 0.24 ENST00000556359.1
LTBP2
latent transforming growth factor beta binding protein 2
chr7_+_144015218 0.24 ENST00000408951.1
OR2A1
olfactory receptor, family 2, subfamily A, member 1
chr15_-_40633101 0.24 ENST00000559313.1
C15orf52
chromosome 15 open reading frame 52
chr4_-_48683188 0.24 ENST00000505759.1
FRYL
FRY-like
chr17_-_47286729 0.24 ENST00000300406.2
ENST00000511277.1
ENST00000511673.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr11_-_72070206 0.23 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr5_+_167718604 0.23 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr2_-_219146839 0.23 ENST00000425694.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr11_+_44587141 0.23 ENST00000227155.4
ENST00000342935.3
ENST00000532544.1
CD82
CD82 molecule
chr5_-_150467221 0.22 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr18_-_56985776 0.22 ENST00000587244.1
CPLX4
complexin 4
chr6_+_31895467 0.22 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr1_-_153363452 0.22 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr5_+_71475449 0.21 ENST00000504492.1
MAP1B
microtubule-associated protein 1B
chr14_-_38028689 0.21 ENST00000553425.1
RP11-356O9.2
RP11-356O9.2
chr8_-_123706338 0.21 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr11_-_798305 0.21 ENST00000531514.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr17_-_56591321 0.20 ENST00000583243.1
MTMR4
myotubularin related protein 4
chr7_+_5229819 0.20 ENST00000288828.4
ENST00000401525.3
ENST00000404704.3
WIPI2
WD repeat domain, phosphoinositide interacting 2
chr16_+_57847684 0.20 ENST00000335616.2
CTD-2600O9.1
uncharacterized protein LOC388282
chr11_+_76494253 0.20 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chrX_+_9880590 0.20 ENST00000452575.1
SHROOM2
shroom family member 2
chr7_-_143929936 0.20 ENST00000391496.1
OR2A42
olfactory receptor, family 2, subfamily A, member 42
chr11_-_1587166 0.20 ENST00000331588.4
DUSP8
dual specificity phosphatase 8
chr1_+_110881945 0.20 ENST00000602849.1
ENST00000487146.2
RBM15
RNA binding motif protein 15
chr1_-_206671061 0.19 ENST00000367119.1
C1orf147
chromosome 1 open reading frame 147
chr12_-_48152611 0.19 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr12_-_94673956 0.19 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr14_+_104710541 0.19 ENST00000419115.1
C14orf144
chromosome 14 open reading frame 144
chr19_+_35485682 0.19 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr19_+_36249044 0.19 ENST00000444637.2
ENST00000396908.4
ENST00000544099.1
C19orf55
chromosome 19 open reading frame 55
chr5_-_150466692 0.19 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr7_+_143078652 0.18 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr8_-_23282820 0.18 ENST00000520871.1
LOXL2
lysyl oxidase-like 2
chr19_-_38743878 0.18 ENST00000587515.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr6_+_31895480 0.18 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chrX_+_118108601 0.18 ENST00000371628.3
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr7_-_150777874 0.18 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr17_-_77925806 0.18 ENST00000574241.2
TBC1D16
TBC1 domain family, member 16
chr12_-_7245018 0.18 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr1_+_180875711 0.17 ENST00000434447.1
RP11-46A10.2
RP11-46A10.2
chr8_-_23282797 0.17 ENST00000524144.1
LOXL2
lysyl oxidase-like 2
chr19_-_18391708 0.17 ENST00000600972.1
JUND
jun D proto-oncogene
chr3_-_52868931 0.17 ENST00000486659.1
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr6_+_30851840 0.17 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr8_-_66701319 0.17 ENST00000379419.4
PDE7A
phosphodiesterase 7A
chr5_+_3596168 0.17 ENST00000302006.3
IRX1
iroquois homeobox 1
chr19_-_13068012 0.17 ENST00000316939.1
GADD45GIP1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr16_+_72142195 0.16 ENST00000563819.1
ENST00000567142.2
DHX38
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr19_-_36499521 0.16 ENST00000397428.3
ENST00000503121.1
ENST00000340477.5
ENST00000324444.3
ENST00000490730.1
SYNE4
spectrin repeat containing, nuclear envelope family member 4
chr15_-_65407524 0.16 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr17_+_49243176 0.16 ENST00000513177.1
NME1-NME2
NME1-NME2 readthrough
chr7_+_143079000 0.16 ENST00000392910.2
ZYX
zyxin
chr8_-_145018080 0.16 ENST00000354589.3
PLEC
plectin
chr12_-_7245125 0.16 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr19_+_41222998 0.16 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr17_-_27621125 0.16 ENST00000579665.1
ENST00000225388.4
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr7_+_2687173 0.16 ENST00000403167.1
TTYH3
tweety family member 3
chr11_+_118826999 0.16 ENST00000264031.2
UPK2
uroplakin 2
chr1_-_33647267 0.16 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr20_-_31124186 0.15 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr19_+_45281118 0.15 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr4_+_8201091 0.15 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr6_-_33663474 0.15 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chrX_+_150151752 0.15 ENST00000325307.7
HMGB3
high mobility group box 3
chr14_-_91282821 0.15 ENST00000553948.1
TTC7B
tetratricopeptide repeat domain 7B
chrX_+_47444613 0.15 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr17_-_77813186 0.15 ENST00000448310.1
ENST00000269397.4
CBX4
chromobox homolog 4
chr10_-_15413035 0.15 ENST00000378116.4
ENST00000455654.1
FAM171A1
family with sequence similarity 171, member A1
chr9_-_140351928 0.15 ENST00000339554.3
NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr3_-_48541537 0.14 ENST00000443308.2
ENST00000417841.1
SHISA5
shisa family member 5
chr12_-_7245152 0.14 ENST00000542220.2
C1R
complement component 1, r subcomponent
chr8_-_41522779 0.14 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
ANK1
ankyrin 1, erythrocytic
chr19_-_42916499 0.14 ENST00000601189.1
ENST00000599211.1
LIPE
lipase, hormone-sensitive
chr17_+_14277419 0.14 ENST00000436469.1
AC022816.2
AC022816.2
chr12_-_52845910 0.14 ENST00000252252.3
KRT6B
keratin 6B
chr14_+_97925151 0.14 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1
CTD-2506J14.1
chr8_-_145018905 0.14 ENST00000398774.2
PLEC
plectin
chr17_+_73512594 0.14 ENST00000333213.6
TSEN54
TSEN54 tRNA splicing endonuclease subunit
chr15_-_75660919 0.14 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
MAN2C1
mannosidase, alpha, class 2C, member 1
chr10_+_102759545 0.14 ENST00000454422.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr16_-_79633799 0.14 ENST00000569649.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr19_+_1241732 0.14 ENST00000215375.2
ENST00000395633.1
ENST00000591660.1
ATP5D
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr8_-_133772794 0.14 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
TMEM71
transmembrane protein 71
chr20_+_3777078 0.14 ENST00000340833.4
CDC25B
cell division cycle 25B
chr18_-_72920372 0.14 ENST00000581620.1
ENST00000582437.1
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr11_-_66675371 0.14 ENST00000393955.2
PC
pyruvate carboxylase
chr9_-_32573130 0.14 ENST00000350021.2
ENST00000379847.3
NDUFB6
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr11_+_45918092 0.13 ENST00000395629.2
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr19_-_4338783 0.13 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr12_-_7245080 0.13 ENST00000541042.1
ENST00000540242.1
C1R
complement component 1, r subcomponent
chr4_+_53525573 0.13 ENST00000503051.1
USP46-AS1
USP46 antisense RNA 1
chrX_-_153583257 0.13 ENST00000438732.1
FLNA
filamin A, alpha
chr17_-_4689727 0.13 ENST00000328739.5
ENST00000354194.4
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr1_-_149785236 0.13 ENST00000331491.1
HIST2H3D
histone cluster 2, H3d
chr19_-_41934635 0.13 ENST00000321702.2
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr12_+_113416265 0.13 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr11_+_110001723 0.13 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr8_-_145016692 0.13 ENST00000357649.2
PLEC
plectin
chr9_+_131644388 0.12 ENST00000372600.4
LRRC8A
leucine rich repeat containing 8 family, member A
chr9_+_131644398 0.12 ENST00000372599.3
LRRC8A
leucine rich repeat containing 8 family, member A
chr17_-_4689649 0.12 ENST00000441199.2
ENST00000416307.2
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr1_+_15272271 0.12 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr6_-_152623231 0.12 ENST00000540663.1
ENST00000537033.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr10_+_124214164 0.12 ENST00000528446.1
ARMS2
age-related maculopathy susceptibility 2
chr5_+_139055021 0.12 ENST00000502716.1
ENST00000503511.1
CXXC5
CXXC finger protein 5
chr7_+_5229904 0.12 ENST00000382384.2
WIPI2
WD repeat domain, phosphoinositide interacting 2
chr1_-_154842741 0.12 ENST00000271915.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr11_+_44587206 0.12 ENST00000525210.1
ENST00000527737.1
ENST00000524704.1
CD82
CD82 molecule
chr2_+_26785409 0.12 ENST00000329615.3
ENST00000409392.1
C2orf70
chromosome 2 open reading frame 70
chr16_+_30662085 0.12 ENST00000569864.1
PRR14
proline rich 14
chr12_-_15082050 0.12 ENST00000540097.1
ERP27
endoplasmic reticulum protein 27
chr1_-_243326612 0.12 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr17_-_79166176 0.12 ENST00000571292.1
AZI1
5-azacytidine induced 1
chr2_+_95963052 0.12 ENST00000295225.5
KCNIP3
Kv channel interacting protein 3, calsenilin
chr9_-_131644202 0.11 ENST00000320665.6
ENST00000436267.2
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr9_-_35111420 0.11 ENST00000378557.1
FAM214B
family with sequence similarity 214, member B
chr19_+_39687596 0.11 ENST00000339852.4
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chrX_+_135279179 0.11 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr17_-_3301704 0.11 ENST00000322608.2
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr3_-_87039662 0.11 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr6_-_39399087 0.11 ENST00000229913.5
ENST00000541946.1
ENST00000394362.1
KIF6
kinesin family member 6
chr5_-_59481406 0.11 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_163100045 0.11 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr17_-_74722672 0.11 ENST00000397625.4
ENST00000445478.2
JMJD6
jumonji domain containing 6
chr4_-_103748271 0.11 ENST00000343106.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr15_+_75940218 0.11 ENST00000308527.5
SNX33
sorting nexin 33
chr8_-_144897138 0.11 ENST00000377533.3
SCRIB
scribbled planar cell polarity protein
chr14_-_75079026 0.11 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2
chr21_+_30502806 0.11 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr6_+_30856507 0.11 ENST00000513240.1
ENST00000424544.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr16_-_25026641 0.11 ENST00000289968.6
ENST00000303665.5
ENST00000455311.2
ENST00000441763.2
ARHGAP17
Rho GTPase activating protein 17
chr1_+_110026544 0.11 ENST00000369870.3
ATXN7L2
ataxin 7-like 2
chr9_+_133710453 0.11 ENST00000318560.5
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr6_-_110736742 0.11 ENST00000368924.3
ENST00000368923.3
DDO
D-aspartate oxidase
chr17_+_1627834 0.11 ENST00000419248.1
ENST00000418841.1
WDR81
WD repeat domain 81
chr11_+_20044096 0.10 ENST00000533917.1
NAV2
neuron navigator 2
chr4_-_174451370 0.10 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr17_+_49242796 0.10 ENST00000514264.2
ENST00000393185.1
NME1-NME2
NME1-NME2 readthrough
chr3_-_87040259 0.10 ENST00000383698.3
VGLL3
vestigial like 3 (Drosophila)
chr7_+_75931861 0.10 ENST00000248553.6
HSPB1
heat shock 27kDa protein 1
chr19_-_49944806 0.10 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr19_-_1568057 0.10 ENST00000402693.4
ENST00000388824.6
MEX3D
mex-3 RNA binding family member D
chr17_-_73775839 0.10 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chr9_+_131644781 0.10 ENST00000259324.5
LRRC8A
leucine rich repeat containing 8 family, member A
chr12_+_117348742 0.10 ENST00000309909.5
ENST00000455858.2
FBXW8
F-box and WD repeat domain containing 8
chr6_+_46761118 0.10 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr20_-_56284816 0.10 ENST00000395819.3
ENST00000341744.3
PMEPA1
prostate transmembrane protein, androgen induced 1
chr1_-_206945830 0.10 ENST00000423557.1
IL10
interleukin 10
chr22_-_50964558 0.10 ENST00000535425.1
ENST00000439934.1
SCO2
SCO2 cytochrome c oxidase assembly protein
chr12_+_27849378 0.10 ENST00000310791.2
REP15
RAB15 effector protein
chr14_+_93389425 0.10 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chr22_+_45072925 0.10 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr17_-_39165366 0.10 ENST00000391588.1
KRTAP3-1
keratin associated protein 3-1
chr1_+_114522049 0.10 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr2_+_120187465 0.10 ENST00000409826.1
ENST00000417645.1
TMEM37
transmembrane protein 37

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG2_NEUROD1_ATOH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.5 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 1.2 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.5 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.4 GO:0018277 protein deamination(GO:0018277)
0.1 0.3 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.3 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.4 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.4 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.3 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.2 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.3 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.2 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.1 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:1900738 dense core granule biogenesis(GO:0061110) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098) negative regulation of monocyte chemotaxis(GO:0090027)
0.0 0.4 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.2 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.0 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.0 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0007320 insemination(GO:0007320)
0.0 0.0 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.0 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.0 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.0 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.1 GO:0046985 negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 0.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.6 GO:0034711 inhibin binding(GO:0034711)
0.1 0.5 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 1.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.6 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.6 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.0 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.0 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway