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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for PAX1_PAX9
Z-value: 0.29
Motif logo
Transcription factors associated with PAX1_PAX9
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
PAX1
|
ENSG00000125813.9 | paired box 1 |
|
PAX9
|
ENSG00000198807.8 | paired box 9 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PAX9 | hg19_v2_chr14_+_37126765_37126799 | -0.59 | 2.2e-01 | Click! |
| PAX1 | hg19_v2_chr20_+_21686290_21686311 | 0.45 | 3.7e-01 | Click! |
Activity profile of PAX1_PAX9 motif
Sorted Z-values of PAX1_PAX9 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_-_67397371 | 0.19 |
ENST00000376693.2
ENST00000301490.4 |
NUDT8
|
nudix (nucleoside diphosphate linked moiety X)-type motif 8 |
| chr4_+_75230853 | 0.15 |
ENST00000244869.2
|
EREG
|
epiregulin |
| chr2_+_119699864 | 0.14 |
ENST00000541757.1
ENST00000412481.1 |
MARCO
|
macrophage receptor with collagenous structure |
| chr2_-_207629997 | 0.12 |
ENST00000454776.2
|
MDH1B
|
malate dehydrogenase 1B, NAD (soluble) |
| chr17_-_3461092 | 0.11 |
ENST00000301365.4
ENST00000572519.1 |
TRPV3
|
transient receptor potential cation channel, subfamily V, member 3 |
| chr8_+_84824920 | 0.10 |
ENST00000523678.1
|
RP11-120I21.2
|
RP11-120I21.2 |
| chr8_-_121825088 | 0.10 |
ENST00000520717.1
|
SNTB1
|
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| chr8_-_23282820 | 0.09 |
ENST00000520871.1
|
LOXL2
|
lysyl oxidase-like 2 |
| chr8_-_23282797 | 0.09 |
ENST00000524144.1
|
LOXL2
|
lysyl oxidase-like 2 |
| chr2_-_207630033 | 0.08 |
ENST00000449792.1
|
MDH1B
|
malate dehydrogenase 1B, NAD (soluble) |
| chr8_-_101965559 | 0.07 |
ENST00000353245.3
|
YWHAZ
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| chr13_+_98086445 | 0.07 |
ENST00000245304.4
|
RAP2A
|
RAP2A, member of RAS oncogene family |
| chr11_+_12308447 | 0.07 |
ENST00000256186.2
|
MICALCL
|
MICAL C-terminal like |
| chr4_+_123747979 | 0.06 |
ENST00000608478.1
|
FGF2
|
fibroblast growth factor 2 (basic) |
| chr9_+_33750515 | 0.06 |
ENST00000361005.5
|
PRSS3
|
protease, serine, 3 |
| chr4_+_123747834 | 0.05 |
ENST00000264498.3
|
FGF2
|
fibroblast growth factor 2 (basic) |
| chr10_+_30723105 | 0.05 |
ENST00000375322.2
|
MAP3K8
|
mitogen-activated protein kinase kinase kinase 8 |
| chr14_+_39703112 | 0.05 |
ENST00000555143.1
ENST00000280082.3 |
MIA2
|
melanoma inhibitory activity 2 |
| chr8_-_101965146 | 0.05 |
ENST00000395957.2
ENST00000395948.2 ENST00000457309.1 |
YWHAZ
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| chr19_-_5838768 | 0.05 |
ENST00000527106.1
ENST00000531199.1 ENST00000529165.1 |
FUT6
|
fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| chr10_-_43904608 | 0.04 |
ENST00000337970.3
|
HNRNPF
|
heterogeneous nuclear ribonucleoprotein F |
| chr11_-_126138808 | 0.04 |
ENST00000332118.6
ENST00000532259.1 |
SRPR
|
signal recognition particle receptor (docking protein) |
| chr9_+_33750667 | 0.04 |
ENST00000457896.1
ENST00000342836.4 ENST00000429677.3 |
PRSS3
|
protease, serine, 3 |
| chr5_+_133842243 | 0.03 |
ENST00000515627.2
|
AC005355.2
|
AC005355.2 |
| chrX_-_153707246 | 0.03 |
ENST00000407062.1
|
LAGE3
|
L antigen family, member 3 |
| chr1_+_26758849 | 0.03 |
ENST00000533087.1
ENST00000531312.1 ENST00000525165.1 ENST00000525326.1 ENST00000525546.1 ENST00000436153.2 ENST00000530781.1 |
DHDDS
|
dehydrodolichyl diphosphate synthase |
| chr18_-_33077556 | 0.03 |
ENST00000589273.1
ENST00000586489.1 |
INO80C
|
INO80 complex subunit C |
| chr4_-_77997126 | 0.02 |
ENST00000537948.1
ENST00000507788.1 ENST00000237654.4 |
CCNI
|
cyclin I |
| chr2_-_175711978 | 0.02 |
ENST00000409089.2
|
CHN1
|
chimerin 1 |
| chr19_-_39104556 | 0.02 |
ENST00000423454.2
|
MAP4K1
|
mitogen-activated protein kinase kinase kinase kinase 1 |
| chr14_+_64854958 | 0.02 |
ENST00000555709.2
ENST00000554739.1 ENST00000554768.1 ENST00000216605.8 |
MTHFD1
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase |
| chr9_+_33795533 | 0.02 |
ENST00000379405.3
|
PRSS3
|
protease, serine, 3 |
| chr6_+_34857019 | 0.02 |
ENST00000360359.3
ENST00000535627.1 |
ANKS1A
|
ankyrin repeat and sterile alpha motif domain containing 1A |
| chr7_-_22234381 | 0.02 |
ENST00000458533.1
|
RAPGEF5
|
Rap guanine nucleotide exchange factor (GEF) 5 |
| chr20_-_17641097 | 0.02 |
ENST00000246043.4
|
RRBP1
|
ribosome binding protein 1 |
| chr2_+_234160340 | 0.02 |
ENST00000417017.1
ENST00000392020.4 ENST00000392018.1 |
ATG16L1
|
autophagy related 16-like 1 (S. cerevisiae) |
| chr10_-_99393242 | 0.02 |
ENST00000370635.3
ENST00000478953.1 ENST00000335628.3 |
MORN4
|
MORN repeat containing 4 |
| chr1_+_26758790 | 0.02 |
ENST00000427245.2
ENST00000525682.2 ENST00000236342.7 ENST00000526219.1 ENST00000374185.3 ENST00000360009.2 |
DHDDS
|
dehydrodolichyl diphosphate synthase |
| chr9_-_124991124 | 0.02 |
ENST00000394319.4
ENST00000340587.3 |
LHX6
|
LIM homeobox 6 |
| chr6_+_74104471 | 0.02 |
ENST00000370336.4
|
DDX43
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| chr8_-_23261589 | 0.02 |
ENST00000524168.1
ENST00000523833.2 ENST00000519243.1 ENST00000389131.3 |
LOXL2
|
lysyl oxidase-like 2 |
| chr9_+_96793076 | 0.02 |
ENST00000375360.3
|
PTPDC1
|
protein tyrosine phosphatase domain containing 1 |
| chr14_-_69261310 | 0.02 |
ENST00000336440.3
|
ZFP36L1
|
ZFP36 ring finger protein-like 1 |
| chr9_+_6716478 | 0.02 |
ENST00000452643.1
|
RP11-390F4.3
|
RP11-390F4.3 |
| chr3_-_57113281 | 0.02 |
ENST00000468466.1
|
ARHGEF3
|
Rho guanine nucleotide exchange factor (GEF) 3 |
| chr2_+_207630081 | 0.02 |
ENST00000236980.6
ENST00000418289.1 ENST00000402774.3 ENST00000403094.3 |
FASTKD2
|
FAST kinase domains 2 |
| chr7_-_19157248 | 0.02 |
ENST00000242261.5
|
TWIST1
|
twist family bHLH transcription factor 1 |
| chr7_-_112758665 | 0.02 |
ENST00000397764.3
|
LINC00998
|
long intergenic non-protein coding RNA 998 |
| chr17_+_15848231 | 0.01 |
ENST00000304222.2
|
ADORA2B
|
adenosine A2b receptor |
| chrX_+_148622513 | 0.01 |
ENST00000393985.3
ENST00000423421.1 ENST00000423540.2 ENST00000434353.2 ENST00000514208.1 |
CXorf40A
|
chromosome X open reading frame 40A |
| chr14_-_91884115 | 0.01 |
ENST00000389857.6
|
CCDC88C
|
coiled-coil domain containing 88C |
| chr1_+_26759295 | 0.01 |
ENST00000430232.1
|
DHDDS
|
dehydrodolichyl diphosphate synthase |
| chr6_-_137366163 | 0.01 |
ENST00000367748.1
|
IL20RA
|
interleukin 20 receptor, alpha |
| chr3_-_57113314 | 0.01 |
ENST00000338458.4
ENST00000468727.1 |
ARHGEF3
|
Rho guanine nucleotide exchange factor (GEF) 3 |
| chr10_-_99393208 | 0.01 |
ENST00000307450.6
|
MORN4
|
MORN repeat containing 4 |
| chr11_+_61522844 | 0.01 |
ENST00000265460.5
|
MYRF
|
myelin regulatory factor |
| chr12_-_101801505 | 0.01 |
ENST00000539055.1
ENST00000551688.1 ENST00000551671.1 ENST00000261636.8 |
ARL1
|
ADP-ribosylation factor-like 1 |
| chr3_+_127771212 | 0.01 |
ENST00000243253.3
ENST00000481210.1 |
SEC61A1
|
Sec61 alpha 1 subunit (S. cerevisiae) |
| chr13_+_21141208 | 0.01 |
ENST00000351808.5
|
IFT88
|
intraflagellar transport 88 homolog (Chlamydomonas) |
| chr7_-_112758589 | 0.01 |
ENST00000413744.1
ENST00000439551.1 ENST00000441359.1 |
LINC00998
|
long intergenic non-protein coding RNA 998 |
| chr3_+_31574189 | 0.01 |
ENST00000295770.2
|
STT3B
|
STT3B, subunit of the oligosaccharyltransferase complex (catalytic) |
| chr1_+_45140360 | 0.01 |
ENST00000418644.1
ENST00000458657.2 ENST00000441519.1 ENST00000535358.1 ENST00000445071.1 |
C1orf228
|
chromosome 1 open reading frame 228 |
| chr19_-_18995029 | 0.01 |
ENST00000596048.1
|
CERS1
|
ceramide synthase 1 |
| chr3_-_25824872 | 0.01 |
ENST00000308710.5
|
NGLY1
|
N-glycanase 1 |
| chr2_-_162931052 | 0.01 |
ENST00000360534.3
|
DPP4
|
dipeptidyl-peptidase 4 |
| chr11_+_63870660 | 0.01 |
ENST00000246841.3
|
FLRT1
|
fibronectin leucine rich transmembrane protein 1 |
| chr5_-_133747589 | 0.00 |
ENST00000458198.2
|
CDKN2AIPNL
|
CDKN2A interacting protein N-terminal like |
| chr2_+_234160217 | 0.00 |
ENST00000392017.4
ENST00000347464.5 ENST00000444735.1 ENST00000373525.5 ENST00000419681.1 |
ATG16L1
|
autophagy related 16-like 1 (S. cerevisiae) |
| chr21_-_33104367 | 0.00 |
ENST00000286835.7
ENST00000399804.1 |
SCAF4
|
SR-related CTD-associated factor 4 |
| chr6_-_170893669 | 0.00 |
ENST00000392090.2
ENST00000542896.1 ENST00000453163.2 ENST00000537445.1 |
PDCD2
|
programmed cell death 2 |
| chr9_-_104249400 | 0.00 |
ENST00000374848.3
|
TMEM246
|
transmembrane protein 246 |
| chr1_+_213031570 | 0.00 |
ENST00000366971.4
|
FLVCR1
|
feline leukemia virus subgroup C cellular receptor 1 |
| chr17_+_37356586 | 0.00 |
ENST00000579260.1
ENST00000582193.1 |
RPL19
|
ribosomal protein L19 |
| chr2_-_39414848 | 0.00 |
ENST00000451199.1
|
CDKL4
|
cyclin-dependent kinase-like 4 |
| chr22_-_41940404 | 0.00 |
ENST00000355209.4
ENST00000337566.5 ENST00000396504.2 ENST00000407461.1 |
POLR3H
|
polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) |
| chr6_+_159290917 | 0.00 |
ENST00000367072.1
|
C6orf99
|
chromosome 6 open reading frame 99 |
| chr10_+_82297658 | 0.00 |
ENST00000339284.2
|
SH2D4B
|
SH2 domain containing 4B |
| chr3_-_25824925 | 0.00 |
ENST00000396649.3
ENST00000428257.1 ENST00000280700.5 |
NGLY1
|
N-glycanase 1 |
| chr6_-_170893742 | 0.00 |
ENST00000443345.2
ENST00000541970.1 |
PDCD2
|
programmed cell death 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of PAX1_PAX9
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0018277 | protein deamination(GO:0018277) |
| 0.0 | 0.1 | GO:0042660 | positive regulation of cell fate specification(GO:0042660) |
| 0.0 | 0.1 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 0.0 | 0.1 | GO:0016094 | polyprenol biosynthetic process(GO:0016094) |
| 0.0 | 0.2 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.0 | 0.1 | GO:0042636 | negative regulation of hair cycle(GO:0042636) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 0.0 | 0.2 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.0 | 0.1 | GO:0002094 | polyprenyltransferase activity(GO:0002094) |