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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PAX4

Z-value: 0.44

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Transcription factors associated with PAX4

Gene Symbol Gene ID Gene Info
PAX4
ENSG00000106331.10 paired box 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX4hg19_v2_chr7_-_127255982_1272559820.473.5e-01Click!

Activity profile of PAX4 motif

Sorted Z-values of PAX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_2977444 0.34 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr5_+_146614579 0.31 ENST00000541094.1
ENST00000398521.3
STK32A
serine/threonine kinase 32A
chr5_-_126409159 0.31 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr2_+_232316906 0.31 ENST00000370380.2
AC017104.2
Uncharacterized protein
chr19_-_17622269 0.30 ENST00000595116.1
CTD-3131K8.2
CTD-3131K8.2
chr12_-_123717711 0.29 ENST00000537854.1
MPHOSPH9
M-phase phosphoprotein 9
chr6_-_10694766 0.27 ENST00000460742.2
ENST00000259983.3
ENST00000379586.1
C6orf52
chromosome 6 open reading frame 52
chr18_+_61254534 0.20 ENST00000269489.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chrX_-_48827976 0.19 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr11_+_114549108 0.18 ENST00000389586.4
ENST00000375475.5
NXPE2
neurexophilin and PC-esterase domain family, member 2
chr18_+_61254570 0.18 ENST00000344731.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr17_+_7253635 0.18 ENST00000571471.1
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr1_+_33439268 0.18 ENST00000594612.1
FKSG48
FKSG48
chr3_-_123339343 0.17 ENST00000578202.1
MYLK
myosin light chain kinase
chr2_-_122042770 0.17 ENST00000263707.5
TFCP2L1
transcription factor CP2-like 1
chr1_+_26644441 0.17 ENST00000374213.2
CD52
CD52 molecule
chr19_-_5624057 0.16 ENST00000590262.1
SAFB2
scaffold attachment factor B2
chr16_-_28608424 0.16 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr4_-_140544386 0.16 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr9_+_92219919 0.16 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr5_+_146614526 0.15 ENST00000397936.3
STK32A
serine/threonine kinase 32A
chr6_+_32605134 0.14 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr4_+_165675269 0.14 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr2_+_99797636 0.14 ENST00000409145.1
MRPL30
mitochondrial ribosomal protein L30
chr3_+_119298523 0.13 ENST00000357003.3
ADPRH
ADP-ribosylarginine hydrolase
chr6_+_133135580 0.13 ENST00000230050.3
RPS12
ribosomal protein S12
chr18_-_53255766 0.13 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr8_+_67344710 0.13 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
ADHFE1
alcohol dehydrogenase, iron containing, 1
chr12_+_56546363 0.13 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr14_+_78227105 0.12 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178
chromosome 14 open reading frame 178
chr5_+_150406527 0.12 ENST00000520059.1
GPX3
glutathione peroxidase 3 (plasma)
chr17_-_46799872 0.12 ENST00000290294.3
PRAC1
prostate cancer susceptibility candidate 1
chr2_-_191184571 0.12 ENST00000392332.3
HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr10_-_70092635 0.12 ENST00000309049.4
PBLD
phenazine biosynthesis-like protein domain containing
chr1_+_244816237 0.11 ENST00000302550.11
DESI2
desumoylating isopeptidase 2
chr1_-_152061537 0.11 ENST00000368806.1
TCHHL1
trichohyalin-like 1
chr16_-_67224002 0.11 ENST00000563889.1
ENST00000564418.1
ENST00000545725.2
ENST00000314586.6
EXOC3L1
exocyst complex component 3-like 1
chr19_+_10959043 0.11 ENST00000397820.4
C19orf38
chromosome 19 open reading frame 38
chr3_-_123339418 0.11 ENST00000583087.1
MYLK
myosin light chain kinase
chr10_-_70092671 0.11 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
PBLD
phenazine biosynthesis-like protein domain containing
chr7_+_26331678 0.11 ENST00000446848.2
SNX10
sorting nexin 10
chr12_+_116997186 0.11 ENST00000306985.4
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr1_+_101702417 0.11 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr8_+_143781883 0.11 ENST00000522591.1
LY6K
lymphocyte antigen 6 complex, locus K
chr19_+_11708259 0.11 ENST00000587939.1
ENST00000588174.1
ZNF627
zinc finger protein 627
chr6_-_113754604 0.10 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr1_-_231376836 0.10 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chr18_-_53089538 0.10 ENST00000566777.1
TCF4
transcription factor 4
chr18_+_61254221 0.10 ENST00000431153.1
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr18_-_53089723 0.10 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr9_+_134103496 0.10 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr4_-_113207048 0.10 ENST00000361717.3
TIFA
TRAF-interacting protein with forkhead-associated domain
chr17_+_7254184 0.10 ENST00000575415.1
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr7_+_80267973 0.10 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)
chr11_-_124622134 0.10 ENST00000326621.5
VSIG2
V-set and immunoglobulin domain containing 2
chr4_-_176733897 0.10 ENST00000393658.2
GPM6A
glycoprotein M6A
chr4_-_76439596 0.09 ENST00000451788.1
ENST00000512706.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr10_-_14920599 0.09 ENST00000609399.1
RP11-398C13.6
RP11-398C13.6
chr9_-_100000957 0.09 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5
RP11-498P14.5
chr19_+_11708229 0.09 ENST00000361113.5
ZNF627
zinc finger protein 627
chr4_+_30723003 0.09 ENST00000543491.1
PCDH7
protocadherin 7
chr10_-_25012115 0.09 ENST00000446003.1
ARHGAP21
Rho GTPase activating protein 21
chr17_+_1674982 0.09 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr15_+_69373210 0.09 ENST00000435479.1
ENST00000559870.1
LINC00277
RP11-809H16.5
long intergenic non-protein coding RNA 277
RP11-809H16.5
chrX_-_102943022 0.09 ENST00000433176.2
MORF4L2
mortality factor 4 like 2
chr12_+_110718428 0.09 ENST00000552636.1
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr4_+_140586922 0.09 ENST00000265498.1
ENST00000506797.1
MGST2
microsomal glutathione S-transferase 2
chr2_-_85839146 0.09 ENST00000306336.5
ENST00000409734.3
C2orf68
chromosome 2 open reading frame 68
chr6_+_32605195 0.08 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chrX_-_101410762 0.08 ENST00000543160.1
ENST00000333643.3
BEX5
brain expressed, X-linked 5
chr12_+_123717458 0.08 ENST00000253233.1
C12orf65
chromosome 12 open reading frame 65
chr14_-_78227476 0.08 ENST00000554775.1
ENST00000555761.1
ENST00000554324.1
ENST00000261531.7
SNW1
SNW domain containing 1
chr1_-_1677358 0.08 ENST00000355439.2
ENST00000400924.1
ENST00000246421.4
SLC35E2
solute carrier family 35, member E2
chr4_-_169931393 0.08 ENST00000504480.1
ENST00000306193.3
CBR4
carbonyl reductase 4
chr1_+_145525015 0.08 ENST00000539363.1
ENST00000538811.1
ITGA10
integrin, alpha 10
chr7_+_134916731 0.08 ENST00000275764.3
STRA8
stimulated by retinoic acid 8
chr19_+_55141861 0.08 ENST00000396327.3
ENST00000324602.7
ENST00000434867.2
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr1_+_244816371 0.08 ENST00000263831.7
DESI2
desumoylating isopeptidase 2
chr13_-_25496926 0.08 ENST00000545981.1
ENST00000381884.4
CENPJ
centromere protein J
chr2_+_99758161 0.08 ENST00000409684.1
C2ORF15
Uncharacterized protein C2orf15
chr3_-_142166904 0.07 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr18_-_53255379 0.07 ENST00000565908.2
TCF4
transcription factor 4
chr12_-_95044309 0.07 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr15_+_63340647 0.07 ENST00000404484.4
TPM1
tropomyosin 1 (alpha)
chr19_-_51961702 0.07 ENST00000430817.1
ENST00000321424.3
ENST00000340550.5
SIGLEC8
sialic acid binding Ig-like lectin 8
chr4_+_174292058 0.07 ENST00000296504.3
SAP30
Sin3A-associated protein, 30kDa
chrX_-_131623982 0.07 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr8_-_101963482 0.07 ENST00000419477.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr16_-_28608364 0.07 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr4_+_95129061 0.07 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_+_95128996 0.07 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr12_+_118573663 0.07 ENST00000261313.2
PEBP1
phosphatidylethanolamine binding protein 1
chr3_-_142166846 0.07 ENST00000463916.1
ENST00000544157.1
XRN1
5'-3' exoribonuclease 1
chr4_+_170541678 0.07 ENST00000360642.3
ENST00000512813.1
CLCN3
chloride channel, voltage-sensitive 3
chr4_+_47487285 0.06 ENST00000273859.3
ENST00000504445.1
ATP10D
ATPase, class V, type 10D
chr1_-_85742773 0.06 ENST00000370580.1
BCL10
B-cell CLL/lymphoma 10
chr4_-_492891 0.06 ENST00000338977.5
ENST00000511833.2
ZNF721
zinc finger protein 721
chr4_+_170541835 0.06 ENST00000504131.2
CLCN3
chloride channel, voltage-sensitive 3
chr7_+_134233840 0.06 ENST00000457545.2
AKR1B15
aldo-keto reductase family 1, member B15
chr12_-_66035922 0.06 ENST00000546198.1
ENST00000535315.1
ENST00000537298.1
RP11-230G5.2
RP11-230G5.2
chrX_-_131547596 0.06 ENST00000538204.1
ENST00000370849.3
MBNL3
muscleblind-like splicing regulator 3
chr16_-_49890016 0.06 ENST00000563137.2
ZNF423
zinc finger protein 423
chr1_-_240775447 0.06 ENST00000318160.4
GREM2
gremlin 2, DAN family BMP antagonist
chr19_+_9361606 0.06 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr4_+_170541660 0.06 ENST00000513761.1
ENST00000347613.4
CLCN3
chloride channel, voltage-sensitive 3
chr16_-_79804394 0.05 ENST00000567993.1
RP11-345M22.2
RP11-345M22.2
chr18_-_3013307 0.05 ENST00000584294.1
LPIN2
lipin 2
chr3_+_69134124 0.05 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr21_-_33651324 0.05 ENST00000290130.3
MIS18A
MIS18 kinetochore protein A
chr12_+_16064258 0.05 ENST00000524480.1
ENST00000531803.1
ENST00000532964.1
DERA
deoxyribose-phosphate aldolase (putative)
chr11_+_20385327 0.05 ENST00000451739.2
ENST00000532505.1
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr6_-_90062543 0.05 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr1_+_231376941 0.05 ENST00000436239.1
ENST00000366647.4
ENST00000366646.3
ENST00000416000.1
GNPAT
glyceronephosphate O-acyltransferase
chr12_-_11091862 0.05 ENST00000537503.1
TAS2R14
taste receptor, type 2, member 14
chr3_+_107318157 0.05 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr12_+_16064106 0.04 ENST00000428559.2
DERA
deoxyribose-phosphate aldolase (putative)
chr3_+_27754397 0.04 ENST00000606069.1
RP11-222K16.2
RP11-222K16.2
chr15_+_63340553 0.04 ENST00000334895.5
TPM1
tropomyosin 1 (alpha)
chr4_+_39184024 0.04 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WDR19
WD repeat domain 19
chr6_+_32407619 0.04 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chrX_+_135067576 0.04 ENST00000370701.1
ENST00000370698.3
ENST00000370695.4
SLC9A6
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
chr19_+_55141948 0.04 ENST00000396332.4
ENST00000427581.2
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr5_+_119799927 0.04 ENST00000407149.2
ENST00000379551.2
PRR16
proline rich 16
chr2_+_201173667 0.04 ENST00000409755.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chrX_-_131547625 0.04 ENST00000394311.2
MBNL3
muscleblind-like splicing regulator 3
chr5_+_118668846 0.04 ENST00000513374.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr19_-_52552051 0.04 ENST00000221315.5
ZNF432
zinc finger protein 432
chr12_+_31812121 0.04 ENST00000395763.3
METTL20
methyltransferase like 20
chr5_-_175395283 0.04 ENST00000513482.1
ENST00000265097.4
THOC3
THO complex 3
chrX_-_31284974 0.04 ENST00000378702.4
DMD
dystrophin
chr5_+_173473662 0.04 ENST00000519717.1
NSG2
Neuron-specific protein family member 2
chr18_+_29027696 0.04 ENST00000257189.4
DSG3
desmoglein 3
chr8_-_74205851 0.04 ENST00000396467.1
RPL7
ribosomal protein L7
chr19_-_53193731 0.04 ENST00000598536.1
ENST00000594682.2
ENST00000601257.1
ZNF83
zinc finger protein 83
chr2_+_190526111 0.04 ENST00000607062.1
ENST00000260952.4
ENST00000425590.1
ENST00000607535.1
ENST00000420250.1
ENST00000606910.1
ENST00000607690.1
ENST00000607829.1
ASNSD1
asparagine synthetase domain containing 1
chr14_+_76072096 0.04 ENST00000555058.1
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr11_-_111741994 0.04 ENST00000398006.2
ALG9
ALG9, alpha-1,2-mannosyltransferase
chr7_+_133812052 0.04 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr8_-_38853990 0.04 ENST00000456845.2
ENST00000397070.2
ENST00000517872.1
ENST00000412303.1
ENST00000456397.2
TM2D2
TM2 domain containing 2
chr5_-_125930877 0.04 ENST00000510111.2
ENST00000509270.1
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr22_-_31688381 0.04 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr1_+_210001309 0.04 ENST00000491415.2
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr13_+_28712614 0.03 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chrX_-_19533379 0.03 ENST00000338883.4
MAP3K15
mitogen-activated protein kinase kinase kinase 15
chr7_-_130080818 0.03 ENST00000343969.5
ENST00000541543.1
ENST00000489512.1
CEP41
centrosomal protein 41kDa
chr15_-_72514866 0.03 ENST00000562997.1
PKM
pyruvate kinase, muscle
chr7_-_16872932 0.03 ENST00000419572.2
ENST00000412973.1
AGR2
anterior gradient 2
chr16_+_53088885 0.03 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr2_+_47630108 0.03 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2
mutS homolog 2
chr17_-_74049720 0.03 ENST00000602720.1
SRP68
signal recognition particle 68kDa
chr2_-_208489707 0.03 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
METTL21A
methyltransferase like 21A
chr2_-_10830093 0.03 ENST00000381685.5
ENST00000345985.3
ENST00000542668.1
ENST00000538384.1
NOL10
nucleolar protein 10
chr5_-_54988448 0.03 ENST00000503817.1
ENST00000512595.1
SLC38A9
solute carrier family 38, member 9
chr6_+_134274354 0.03 ENST00000367869.1
TBPL1
TBP-like 1
chr8_-_101963677 0.03 ENST00000395956.3
ENST00000395953.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr1_+_162039558 0.03 ENST00000530878.1
ENST00000361897.5
NOS1AP
nitric oxide synthase 1 (neuronal) adaptor protein
chr11_+_46740730 0.03 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2
coagulation factor II (thrombin)
chr2_-_20251744 0.03 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr7_-_96654133 0.03 ENST00000486603.2
ENST00000222598.4
DLX5
distal-less homeobox 5
chr11_+_1874200 0.03 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr2_+_15731289 0.03 ENST00000381341.2
DDX1
DEAD (Asp-Glu-Ala-Asp) box helicase 1
chr11_+_57529234 0.03 ENST00000360682.6
ENST00000361796.4
ENST00000529526.1
ENST00000426142.2
ENST00000399050.4
ENST00000361391.6
ENST00000361332.4
ENST00000532463.1
ENST00000529986.1
ENST00000358694.6
ENST00000532787.1
ENST00000533667.1
ENST00000532649.1
ENST00000528621.1
ENST00000530748.1
ENST00000428599.2
ENST00000527467.1
ENST00000528232.1
ENST00000531014.1
ENST00000526772.1
ENST00000529873.1
ENST00000525902.1
ENST00000532844.1
ENST00000526357.1
ENST00000530094.1
ENST00000415361.2
ENST00000532245.1
ENST00000534579.1
ENST00000526938.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr2_+_231860830 0.03 ENST00000424440.1
ENST00000452881.1
ENST00000433428.2
ENST00000455816.1
ENST00000440792.1
ENST00000423134.1
SPATA3
spermatogenesis associated 3
chr14_-_50559361 0.03 ENST00000305273.1
C14orf183
chromosome 14 open reading frame 183
chr21_+_43934633 0.03 ENST00000398343.2
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chrX_-_102942961 0.03 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
MORF4L2
mortality factor 4 like 2
chr11_+_20385231 0.03 ENST00000530266.1
ENST00000421577.2
ENST00000443524.2
ENST00000419348.2
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr17_-_33390667 0.03 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr11_+_134144139 0.03 ENST00000389887.5
GLB1L3
galactosidase, beta 1-like 3
chr1_+_90308981 0.03 ENST00000527156.1
LRRC8D
leucine rich repeat containing 8 family, member D
chr9_+_100000717 0.03 ENST00000375205.2
ENST00000357054.1
ENST00000395220.1
ENST00000375202.2
ENST00000411667.2
CCDC180
coiled-coil domain containing 180
chr4_-_84030996 0.03 ENST00000411416.2
PLAC8
placenta-specific 8
chr7_-_86595190 0.02 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324L
KIAA1324-like
chr2_-_217560248 0.02 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr8_-_116680833 0.02 ENST00000220888.5
TRPS1
trichorhinophalangeal syndrome I
chr5_-_142782862 0.02 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr8_-_13134045 0.02 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr16_-_28621312 0.02 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr2_+_216176761 0.02 ENST00000540518.1
ENST00000435675.1
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr18_-_32957260 0.02 ENST00000587422.1
ENST00000306346.1
ENST00000589332.1
ENST00000586687.1
ENST00000585522.1
ZNF396
zinc finger protein 396
chr1_-_151032040 0.02 ENST00000540998.1
ENST00000357235.5
CDC42SE1
CDC42 small effector 1
chr11_-_124622083 0.02 ENST00000403470.1
VSIG2
V-set and immunoglobulin domain containing 2
chr15_-_82641706 0.02 ENST00000439287.4
GOLGA6L10
golgin A6 family-like 10
chr11_-_93276582 0.02 ENST00000298966.2
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr16_-_79804435 0.02 ENST00000562921.1
ENST00000566729.1
RP11-345M22.2
RP11-345M22.2
chr4_-_169931231 0.02 ENST00000504561.1
CBR4
carbonyl reductase 4
chr1_+_162601774 0.02 ENST00000415555.1
DDR2
discoidin domain receptor tyrosine kinase 2
chr2_-_208489275 0.02 ENST00000272839.3
ENST00000426075.1
METTL21A
methyltransferase like 21A
chr3_+_46283863 0.02 ENST00000545097.1
ENST00000541018.1
CCR3
chemokine (C-C motif) receptor 3
chr17_-_26697304 0.02 ENST00000536498.1
VTN
vitronectin
chr2_+_99797542 0.02 ENST00000338148.3
ENST00000512183.2
MRPL30
C2orf15
mitochondrial ribosomal protein L30
chromosome 2 open reading frame 15
chr11_-_96239990 0.02 ENST00000511243.2
JRKL-AS1
JRKL antisense RNA 1
chr4_-_171011323 0.02 ENST00000509167.1
ENST00000353187.2
ENST00000507375.1
ENST00000515480.1
AADAT
aminoadipate aminotransferase
chr19_+_14544099 0.02 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1
protein kinase N1
chr7_-_23053719 0.02 ENST00000432176.2
ENST00000440481.1
FAM126A
family with sequence similarity 126, member A
chr13_-_46543805 0.02 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr1_+_145524891 0.02 ENST00000369304.3
ITGA10
integrin, alpha 10
chr9_-_20621834 0.02 ENST00000429426.2
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chrX_+_106163626 0.02 ENST00000336803.1
CLDN2
claudin 2
chr5_-_20575959 0.02 ENST00000507958.1
CDH18
cadherin 18, type 2

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.1 GO:0035548 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0032765 lymphotoxin A production(GO:0032641) positive regulation of mast cell cytokine production(GO:0032765) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.0 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.0 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.0 GO:1905033 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.0 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.0 GO:0060166 olfactory pit development(GO:0060166)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.0 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030109 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse