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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for PBX2
Z-value: 0.37
Motif logo
Transcription factors associated with PBX2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
PBX2
|
ENSG00000204304.7 | PBX homeobox 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PBX2 | hg19_v2_chr6_-_32157947_32157992 | -0.25 | 6.3e-01 | Click! |
Activity profile of PBX2 motif
Sorted Z-values of PBX2 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_-_30642728 | 0.40 |
ENST00000403987.3
|
LIF
|
leukemia inhibitory factor |
| chr18_-_72920372 | 0.18 |
ENST00000581620.1
ENST00000582437.1 |
ZADH2
|
zinc binding alcohol dehydrogenase domain containing 2 |
| chr17_+_7758374 | 0.16 |
ENST00000301599.6
ENST00000574668.1 |
TMEM88
|
transmembrane protein 88 |
| chr2_+_12857043 | 0.14 |
ENST00000381465.2
|
TRIB2
|
tribbles pseudokinase 2 |
| chr10_-_45474237 | 0.10 |
ENST00000448778.1
ENST00000298295.3 |
C10orf10
|
chromosome 10 open reading frame 10 |
| chr9_-_128246769 | 0.09 |
ENST00000444226.1
|
MAPKAP1
|
mitogen-activated protein kinase associated protein 1 |
| chr2_+_12857015 | 0.09 |
ENST00000155926.4
|
TRIB2
|
tribbles pseudokinase 2 |
| chr2_-_31440377 | 0.08 |
ENST00000444918.2
ENST00000403897.3 |
CAPN14
|
calpain 14 |
| chr10_+_69869237 | 0.08 |
ENST00000373675.3
|
MYPN
|
myopalladin |
| chr16_-_11492366 | 0.07 |
ENST00000595360.1
|
CTD-3088G3.8
|
Protein LOC388210 |
| chr3_-_52864680 | 0.06 |
ENST00000406595.1
ENST00000485816.1 ENST00000434759.3 ENST00000346281.5 ENST00000266041.4 |
ITIH4
|
inter-alpha-trypsin inhibitor heavy chain family, member 4 |
| chr7_+_134528635 | 0.06 |
ENST00000445569.2
|
CALD1
|
caldesmon 1 |
| chr15_+_67418047 | 0.05 |
ENST00000540846.2
|
SMAD3
|
SMAD family member 3 |
| chr8_-_6420930 | 0.05 |
ENST00000325203.5
|
ANGPT2
|
angiopoietin 2 |
| chr17_-_29151686 | 0.04 |
ENST00000544695.1
|
CRLF3
|
cytokine receptor-like factor 3 |
| chr17_+_8191815 | 0.04 |
ENST00000226105.6
ENST00000407006.4 ENST00000580434.1 ENST00000439238.3 |
RANGRF
|
RAN guanine nucleotide release factor |
| chr6_+_160211481 | 0.04 |
ENST00000367034.4
|
MRPL18
|
mitochondrial ribosomal protein L18 |
| chr3_+_188889737 | 0.04 |
ENST00000345063.3
|
TPRG1
|
tumor protein p63 regulated 1 |
| chr11_-_62432641 | 0.04 |
ENST00000528405.1
ENST00000524958.1 ENST00000525675.1 |
RP11-831H9.11
C11orf48
|
Uncharacterized protein chromosome 11 open reading frame 48 |
| chr4_-_100065440 | 0.03 |
ENST00000508393.1
ENST00000265512.7 |
ADH4
|
alcohol dehydrogenase 4 (class II), pi polypeptide |
| chr12_-_28124903 | 0.03 |
ENST00000395872.1
ENST00000354417.3 ENST00000201015.4 |
PTHLH
|
parathyroid hormone-like hormone |
| chr16_+_1832902 | 0.03 |
ENST00000262302.9
ENST00000563136.1 ENST00000565987.1 ENST00000543305.1 ENST00000568287.1 ENST00000565134.1 |
NUBP2
|
nucleotide binding protein 2 |
| chr7_-_32529973 | 0.03 |
ENST00000410044.1
ENST00000409987.1 ENST00000409782.1 ENST00000450169.2 |
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| chr14_+_64854958 | 0.03 |
ENST00000555709.2
ENST00000554739.1 ENST00000554768.1 ENST00000216605.8 |
MTHFD1
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase |
| chr3_+_129159039 | 0.03 |
ENST00000507564.1
ENST00000431818.2 ENST00000504021.1 ENST00000349441.2 ENST00000348417.2 ENST00000440957.2 |
IFT122
|
intraflagellar transport 122 homolog (Chlamydomonas) |
| chr14_+_58765305 | 0.03 |
ENST00000445108.1
|
ARID4A
|
AT rich interactive domain 4A (RBP1-like) |
| chr4_+_71019903 | 0.03 |
ENST00000344526.5
|
C4orf40
|
chromosome 4 open reading frame 40 |
| chr17_-_29624343 | 0.03 |
ENST00000247271.4
|
OMG
|
oligodendrocyte myelin glycoprotein |
| chr12_-_28125638 | 0.03 |
ENST00000545234.1
|
PTHLH
|
parathyroid hormone-like hormone |
| chr7_-_112727774 | 0.02 |
ENST00000297146.3
ENST00000501255.2 |
GPR85
|
G protein-coupled receptor 85 |
| chr1_+_207038699 | 0.02 |
ENST00000367098.1
|
IL20
|
interleukin 20 |
| chr3_-_112013071 | 0.02 |
ENST00000487372.1
ENST00000486574.1 ENST00000305815.5 |
SLC9C1
|
solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1 |
| chr8_+_110098850 | 0.02 |
ENST00000518632.1
|
TRHR
|
thyrotropin-releasing hormone receptor |
| chr2_+_27255806 | 0.02 |
ENST00000238788.9
ENST00000404032.3 |
TMEM214
|
transmembrane protein 214 |
| chr7_-_33140498 | 0.01 |
ENST00000448915.1
|
RP9
|
retinitis pigmentosa 9 (autosomal dominant) |
| chr12_+_53835383 | 0.01 |
ENST00000429243.2
|
PRR13
|
proline rich 13 |
| chr5_-_75008244 | 0.01 |
ENST00000510798.1
ENST00000446329.2 |
POC5
|
POC5 centriolar protein |
| chr11_-_2162162 | 0.01 |
ENST00000381389.1
|
IGF2
|
insulin-like growth factor 2 (somatomedin A) |
| chr2_-_99917639 | 0.01 |
ENST00000308528.4
|
LYG1
|
lysozyme G-like 1 |
| chr1_-_39339777 | 0.01 |
ENST00000397572.2
|
MYCBP
|
MYC binding protein |
| chr11_+_69455855 | 0.01 |
ENST00000227507.2
ENST00000536559.1 |
CCND1
|
cyclin D1 |
| chr6_+_53976211 | 0.01 |
ENST00000503951.1
|
MLIP
|
muscular LMNA-interacting protein |
| chr3_-_129158850 | 0.01 |
ENST00000503197.1
ENST00000249910.1 ENST00000429544.2 ENST00000507208.1 |
MBD4
|
methyl-CpG binding domain protein 4 |
| chr14_+_38033252 | 0.01 |
ENST00000554829.1
|
RP11-356O9.1
|
RP11-356O9.1 |
| chr17_-_29151794 | 0.01 |
ENST00000324238.6
|
CRLF3
|
cytokine receptor-like factor 3 |
| chr12_+_53835539 | 0.01 |
ENST00000547368.1
ENST00000379786.4 ENST00000551945.1 |
PRR13
|
proline rich 13 |
| chr6_+_26045603 | 0.01 |
ENST00000540144.1
|
HIST1H3C
|
histone cluster 1, H3c |
| chr2_+_33661382 | 0.00 |
ENST00000402538.3
|
RASGRP3
|
RAS guanyl releasing protein 3 (calcium and DAG-regulated) |
| chr12_+_53835425 | 0.00 |
ENST00000549924.1
|
PRR13
|
proline rich 13 |
| chr3_+_120626919 | 0.00 |
ENST00000273666.6
ENST00000471454.1 ENST00000472879.1 ENST00000497029.1 ENST00000492541.1 |
STXBP5L
|
syntaxin binding protein 5-like |
| chr10_+_124320195 | 0.00 |
ENST00000359586.6
|
DMBT1
|
deleted in malignant brain tumors 1 |
| chr4_+_71017791 | 0.00 |
ENST00000502294.1
|
C4orf40
|
chromosome 4 open reading frame 40 |
| chr3_-_47932759 | 0.00 |
ENST00000441748.2
ENST00000335271.5 |
MAP4
|
microtubule-associated protein 4 |
| chr2_-_190044480 | 0.00 |
ENST00000374866.3
|
COL5A2
|
collagen, type V, alpha 2 |
| chr12_-_39734783 | 0.00 |
ENST00000552961.1
|
KIF21A
|
kinesin family member 21A |
| chr10_+_47894572 | 0.00 |
ENST00000355876.5
|
FAM21B
|
family with sequence similarity 21, member B |
| chr11_+_68228186 | 0.00 |
ENST00000393799.2
ENST00000393800.2 ENST00000528635.1 ENST00000533127.1 ENST00000529907.1 ENST00000529344.1 ENST00000534534.1 ENST00000524845.1 ENST00000265637.4 ENST00000524904.1 ENST00000393801.3 ENST00000265636.5 ENST00000529710.1 |
PPP6R3
|
protein phosphatase 6, regulatory subunit 3 |
| chr3_+_129158926 | 0.00 |
ENST00000347300.2
ENST00000296266.3 |
IFT122
|
intraflagellar transport 122 homolog (Chlamydomonas) |
| chr2_+_20646824 | 0.00 |
ENST00000272233.4
|
RHOB
|
ras homolog family member B |
| chr4_-_100065389 | 0.00 |
ENST00000512499.1
|
ADH4
|
alcohol dehydrogenase 4 (class II), pi polypeptide |
| chrX_+_46696372 | 0.00 |
ENST00000218340.3
|
RP2
|
retinitis pigmentosa 2 (X-linked recessive) |
Network of associatons between targets according to the STRING database.
First level regulatory network of PBX2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.1 | 0.2 | GO:0045081 | negative regulation of interleukin-10 biosynthetic process(GO:0045081) |
| 0.0 | 0.1 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.0 | 0.0 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 0.0 | 0.1 | GO:0050928 | negative regulation of positive chemotaxis(GO:0050928) |
| 0.0 | 0.0 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0005146 | leukemia inhibitory factor receptor binding(GO:0005146) |
| 0.0 | 0.2 | GO:0047522 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
| 0.0 | 0.2 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.0 | 0.0 | GO:0004487 | methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |