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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for PITX2
Z-value: 0.20
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Transcription factors associated with PITX2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
PITX2
|
ENSG00000164093.11 | paired like homeodomain 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PITX2 | hg19_v2_chr4_-_111544254_111544270 | -0.66 | 1.5e-01 | Click! |
Activity profile of PITX2 motif
Sorted Z-values of PITX2 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_+_70916119 | 0.09 |
ENST00000246896.3
ENST00000511674.1 |
HTN1
|
histatin 1 |
| chr3_-_49837254 | 0.07 |
ENST00000412678.2
ENST00000343366.4 ENST00000487256.1 |
CDHR4
|
cadherin-related family member 4 |
| chr9_-_98268883 | 0.07 |
ENST00000551630.1
ENST00000548420.1 |
PTCH1
|
patched 1 |
| chr14_+_75988851 | 0.06 |
ENST00000555504.1
|
BATF
|
basic leucine zipper transcription factor, ATF-like |
| chr4_-_68620053 | 0.06 |
ENST00000420975.2
ENST00000226413.4 |
GNRHR
|
gonadotropin-releasing hormone receptor |
| chr16_-_12070468 | 0.06 |
ENST00000538896.1
|
RP11-166B2.1
|
Putative NPIP-like protein LOC729978 |
| chr7_-_128415844 | 0.05 |
ENST00000249389.2
|
OPN1SW
|
opsin 1 (cone pigments), short-wave-sensitive |
| chr9_+_8858102 | 0.04 |
ENST00000447950.1
ENST00000430766.1 |
RP11-75C9.1
|
RP11-75C9.1 |
| chr5_-_64920115 | 0.04 |
ENST00000381018.3
ENST00000274327.7 |
TRIM23
|
tripartite motif containing 23 |
| chr6_+_130339710 | 0.04 |
ENST00000526087.1
ENST00000533560.1 ENST00000361794.2 |
L3MBTL3
|
l(3)mbt-like 3 (Drosophila) |
| chr19_-_19314162 | 0.03 |
ENST00000420605.3
ENST00000544883.1 ENST00000538165.2 ENST00000331552.7 |
NR2C2AP
|
nuclear receptor 2C2-associated protein |
| chr17_+_4643300 | 0.03 |
ENST00000433935.1
|
ZMYND15
|
zinc finger, MYND-type containing 15 |
| chr17_+_4643337 | 0.03 |
ENST00000592813.1
|
ZMYND15
|
zinc finger, MYND-type containing 15 |
| chr2_-_65659762 | 0.03 |
ENST00000440972.1
|
SPRED2
|
sprouty-related, EVH1 domain containing 2 |
| chrM_+_9207 | 0.03 |
ENST00000362079.2
|
MT-CO3
|
mitochondrially encoded cytochrome c oxidase III |
| chr3_+_139062838 | 0.03 |
ENST00000310776.4
ENST00000465056.1 ENST00000465373.1 |
MRPS22
|
mitochondrial ribosomal protein S22 |
| chr1_-_31230650 | 0.03 |
ENST00000294507.3
|
LAPTM5
|
lysosomal protein transmembrane 5 |
| chr1_+_205538165 | 0.03 |
ENST00000536357.1
|
MFSD4
|
major facilitator superfamily domain containing 4 |
| chrX_-_48931648 | 0.03 |
ENST00000376386.3
ENST00000376390.4 |
PRAF2
|
PRA1 domain family, member 2 |
| chr11_-_75017734 | 0.03 |
ENST00000532525.1
|
ARRB1
|
arrestin, beta 1 |
| chr22_-_39096661 | 0.03 |
ENST00000216039.5
|
JOSD1
|
Josephin domain containing 1 |
| chr1_-_165414414 | 0.03 |
ENST00000359842.5
|
RXRG
|
retinoid X receptor, gamma |
| chr15_+_41221536 | 0.03 |
ENST00000249749.5
|
DLL4
|
delta-like 4 (Drosophila) |
| chr6_-_53013620 | 0.02 |
ENST00000259803.7
|
GCM1
|
glial cells missing homolog 1 (Drosophila) |
| chr9_-_127358087 | 0.02 |
ENST00000475178.1
|
NR6A1
|
nuclear receptor subfamily 6, group A, member 1 |
| chr9_-_8857776 | 0.02 |
ENST00000481079.1
|
PTPRD
|
protein tyrosine phosphatase, receptor type, D |
| chr3_+_158787098 | 0.02 |
ENST00000397832.2
ENST00000451172.1 ENST00000482126.1 |
IQCJ
|
IQ motif containing J |
| chr12_+_7941989 | 0.02 |
ENST00000229307.4
|
NANOG
|
Nanog homeobox |
| chrX_-_33357558 | 0.02 |
ENST00000288447.4
|
DMD
|
dystrophin |
| chr11_-_36619771 | 0.02 |
ENST00000311485.3
ENST00000527033.1 ENST00000532616.1 |
RAG2
|
recombination activating gene 2 |
| chr17_-_40021656 | 0.02 |
ENST00000319121.3
|
KLHL11
|
kelch-like family member 11 |
| chrX_+_107069063 | 0.02 |
ENST00000262843.6
|
MID2
|
midline 2 |
| chr18_-_47017956 | 0.02 |
ENST00000584895.1
ENST00000332968.6 ENST00000580210.1 ENST00000579408.1 |
RPL17-C18orf32
RPL17
|
RPL17-C18orf32 readthrough ribosomal protein L17 |
| chr4_-_36245561 | 0.01 |
ENST00000506189.1
|
ARAP2
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| chr13_-_36429763 | 0.01 |
ENST00000379893.1
|
DCLK1
|
doublecortin-like kinase 1 |
| chr9_+_34458771 | 0.01 |
ENST00000437363.1
ENST00000242317.4 |
DNAI1
|
dynein, axonemal, intermediate chain 1 |
| chr4_-_76912070 | 0.01 |
ENST00000395711.4
ENST00000356260.5 |
SDAD1
|
SDA1 domain containing 1 |
| chr11_-_119217365 | 0.01 |
ENST00000360167.4
ENST00000555262.1 ENST00000449574.2 ENST00000445041.2 |
MFRP
C1QTNF5
|
membrane frizzled-related protein C1q and tumor necrosis factor related protein 5 |
| chr17_-_46657473 | 0.01 |
ENST00000332503.5
|
HOXB4
|
homeobox B4 |
| chr19_+_2476116 | 0.01 |
ENST00000215631.4
ENST00000587345.1 |
GADD45B
|
growth arrest and DNA-damage-inducible, beta |
| chr3_+_158787041 | 0.01 |
ENST00000471575.1
ENST00000476809.1 ENST00000485419.1 |
IQCJ-SCHIP1
|
IQCJ-SCHIP1 readthrough |
| chr17_-_4643161 | 0.01 |
ENST00000574412.1
|
CXCL16
|
chemokine (C-X-C motif) ligand 16 |
| chr6_-_160209471 | 0.01 |
ENST00000539948.1
|
TCP1
|
t-complex 1 |
| chr11_+_61522844 | 0.01 |
ENST00000265460.5
|
MYRF
|
myelin regulatory factor |
| chr9_-_110251836 | 0.01 |
ENST00000374672.4
|
KLF4
|
Kruppel-like factor 4 (gut) |
| chr16_-_5116025 | 0.01 |
ENST00000472572.3
ENST00000315997.5 ENST00000422873.1 ENST00000350219.4 |
C16orf89
|
chromosome 16 open reading frame 89 |
| chr11_-_5248294 | 0.01 |
ENST00000335295.4
|
HBB
|
hemoglobin, beta |
| chr12_+_40787194 | 0.01 |
ENST00000425730.2
ENST00000454784.4 |
MUC19
|
mucin 19, oligomeric |
| chr2_+_3622893 | 0.01 |
ENST00000407445.3
ENST00000403564.1 |
RPS7
|
ribosomal protein S7 |
| chr10_-_61900762 | 0.01 |
ENST00000355288.2
|
ANK3
|
ankyrin 3, node of Ranvier (ankyrin G) |
| chr10_-_49482907 | 0.01 |
ENST00000374201.3
ENST00000407470.4 |
FRMPD2
|
FERM and PDZ domain containing 2 |
| chr13_-_95131923 | 0.01 |
ENST00000377028.5
ENST00000446125.1 |
DCT
|
dopachrome tautomerase |
| chr17_+_79495397 | 0.01 |
ENST00000417245.2
ENST00000334850.7 |
FSCN2
|
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) |
| chr13_+_73632897 | 0.01 |
ENST00000377687.4
|
KLF5
|
Kruppel-like factor 5 (intestinal) |
| chr1_+_201979645 | 0.00 |
ENST00000367284.5
ENST00000367283.3 |
ELF3
|
E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| chr18_-_3880051 | 0.00 |
ENST00000584874.1
|
DLGAP1
|
discs, large (Drosophila) homolog-associated protein 1 |
| chr2_+_201994569 | 0.00 |
ENST00000457277.1
|
CFLAR
|
CASP8 and FADD-like apoptosis regulator |
| chr7_-_122840015 | 0.00 |
ENST00000194130.2
|
SLC13A1
|
solute carrier family 13 (sodium/sulfate symporter), member 1 |
| chr16_+_58010339 | 0.00 |
ENST00000290871.5
ENST00000441824.2 |
TEPP
|
testis, prostate and placenta expressed |
| chr8_-_10512569 | 0.00 |
ENST00000382483.3
|
RP1L1
|
retinitis pigmentosa 1-like 1 |
| chr3_-_69249863 | 0.00 |
ENST00000478263.1
ENST00000462512.1 |
FRMD4B
|
FERM domain containing 4B |
Network of associatons between targets according to the STRING database.
First level regulatory network of PITX2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0010157 | response to chlorate(GO:0010157) |
| 0.0 | 0.1 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0004968 | gonadotropin-releasing hormone receptor activity(GO:0004968) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.0 | 0.1 | REACTOME OPSINS | Genes involved in Opsins |