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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for POU5F1_POU2F3

Z-value: 0.81

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Transcription factors associated with POU5F1_POU2F3

Gene Symbol Gene ID Gene Info
POU5F1
ENSG00000204531.11 POU class 5 homeobox 1
POU2F3
ENSG00000137709.5 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU5F1hg19_v2_chr6_-_31138439_311384750.768.2e-02Click!
POU2F3hg19_v2_chr11_+_120110863_120110908-0.128.3e-01Click!

Activity profile of POU5F1_POU2F3 motif

Sorted Z-values of POU5F1_POU2F3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_38171681 1.91 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr1_-_153013588 1.75 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr1_-_153044083 1.73 ENST00000341611.2
SPRR2B
small proline-rich protein 2B
chr1_-_153066998 1.57 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr17_+_38171614 1.46 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr6_+_26251835 1.36 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr9_-_35658007 1.33 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr1_-_153029980 0.99 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr9_+_136325089 0.77 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1
calcium channel flower domain containing 1
chr7_-_17500294 0.70 ENST00000439046.1
AC019117.2
AC019117.2
chr5_+_159895275 0.64 ENST00000517927.1
MIR146A
microRNA 146a
chr12_+_113344582 0.57 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113344811 0.55 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_-_7245125 0.55 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr2_+_89952792 0.55 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr6_+_27861190 0.53 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr12_+_113354341 0.53 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr19_+_41305085 0.50 ENST00000303961.4
EGLN2
egl-9 family hypoxia-inducible factor 2
chr7_+_22766766 0.50 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr6_+_31588478 0.49 ENST00000376007.4
ENST00000376033.2
PRRC2A
proline-rich coiled-coil 2A
chr2_-_113594279 0.49 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr1_-_153113927 0.48 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr6_+_26217159 0.47 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr12_+_93115281 0.47 ENST00000549856.1
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr1_-_153363452 0.45 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr19_-_1021113 0.44 ENST00000333175.5
ENST00000356663.3
TMEM259
transmembrane protein 259
chr19_+_56111680 0.44 ENST00000301073.3
ZNF524
zinc finger protein 524
chr12_-_7245018 0.43 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr19_-_41903161 0.42 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr1_+_32666188 0.40 ENST00000421922.2
CCDC28B
coiled-coil domain containing 28B
chr6_+_131571535 0.37 ENST00000474850.2
AKAP7
A kinase (PRKA) anchor protein 7
chr12_-_7245080 0.37 ENST00000541042.1
ENST00000540242.1
C1R
complement component 1, r subcomponent
chr11_-_18258342 0.37 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr6_+_31895467 0.36 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr12_+_132312931 0.35 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr12_+_7053172 0.35 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr12_+_122064398 0.35 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr12_-_123201337 0.35 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr18_-_61311485 0.34 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr19_-_1132207 0.34 ENST00000438103.2
SBNO2
strawberry notch homolog 2 (Drosophila)
chr7_-_155437075 0.34 ENST00000401694.1
AC009403.2
Protein LOC100506302
chr16_-_74808710 0.34 ENST00000219368.3
ENST00000544337.1
FA2H
fatty acid 2-hydroxylase
chr19_-_12267524 0.33 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
ZNF625
zinc finger protein 625
chr1_+_149822620 0.33 ENST00000369159.2
HIST2H2AA4
histone cluster 2, H2aa4
chr2_+_90248739 0.33 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr7_-_100183742 0.33 ENST00000310300.6
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr2_-_152118276 0.33 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr16_-_28936007 0.33 ENST00000568703.1
ENST00000567483.1
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr17_+_62461569 0.32 ENST00000603557.1
ENST00000605096.1
MILR1
mast cell immunoglobulin-like receptor 1
chr6_+_31895480 0.32 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr19_-_44123734 0.31 ENST00000598676.1
ZNF428
zinc finger protein 428
chr12_-_11175219 0.31 ENST00000390673.2
TAS2R19
taste receptor, type 2, member 19
chr2_-_61108449 0.31 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr1_+_32538520 0.31 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
TMEM39B
transmembrane protein 39B
chrX_-_55020511 0.30 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_+_90192768 0.30 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr19_-_17516449 0.29 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr7_-_41742697 0.29 ENST00000242208.4
INHBA
inhibin, beta A
chr1_-_153085984 0.29 ENST00000468739.1
SPRR2F
small proline-rich protein 2F
chr1_+_32538492 0.29 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr12_+_122064673 0.29 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr15_-_80263506 0.29 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr6_-_27860956 0.29 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr19_+_41305330 0.28 ENST00000593972.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr22_+_22764088 0.28 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr12_+_7052974 0.28 ENST00000544681.1
ENST00000537087.1
C12orf57
chromosome 12 open reading frame 57
chr12_-_7245152 0.28 ENST00000542220.2
C1R
complement component 1, r subcomponent
chr12_-_123187890 0.27 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr1_+_152975488 0.27 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr4_+_40194609 0.27 ENST00000508513.1
RHOH
ras homolog family member H
chr9_-_116062045 0.26 ENST00000478815.1
RNF183
ring finger protein 183
chr2_+_68962014 0.26 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr17_-_47841485 0.26 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr11_+_313503 0.26 ENST00000528780.1
ENST00000328221.5
IFITM1
interferon induced transmembrane protein 1
chr8_+_72755367 0.25 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr6_-_27114577 0.25 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr3_-_186262166 0.24 ENST00000307944.5
CRYGS
crystallin, gamma S
chr20_+_361261 0.24 ENST00000217233.3
TRIB3
tribbles pseudokinase 3
chr5_-_119669160 0.24 ENST00000514240.1
CTC-552D5.1
CTC-552D5.1
chr6_-_26032288 0.24 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr5_+_43033818 0.24 ENST00000607830.1
CTD-2035E11.4
CTD-2035E11.4
chr5_-_73936544 0.23 ENST00000509127.2
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr6_-_27100529 0.23 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ
histone cluster 1, H2bj
chr1_-_149814478 0.23 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr1_-_152539248 0.23 ENST00000368789.1
LCE3E
late cornified envelope 3E
chr4_+_76481258 0.23 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr12_-_122018114 0.23 ENST00000539394.1
KDM2B
lysine (K)-specific demethylase 2B
chr12_-_10573149 0.23 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
KLRC3
killer cell lectin-like receptor subfamily C, member 3
chr19_-_19281054 0.23 ENST00000424583.2
ENST00000410050.1
ENST00000409224.1
ENST00000409447.2
MEF2B
myocyte enhancer factor 2B
chr16_-_4323015 0.22 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr12_+_93096619 0.22 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr2_+_105050794 0.21 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr19_-_54974894 0.21 ENST00000333834.4
LENG9
leukocyte receptor cluster (LRC) member 9
chr19_+_19144666 0.21 ENST00000535288.1
ENST00000538663.1
ARMC6
armadillo repeat containing 6
chr5_-_172198190 0.21 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr15_+_67358163 0.21 ENST00000327367.4
SMAD3
SMAD family member 3
chrY_+_15418467 0.21 ENST00000595988.1
AC010877.1
Uncharacterized protein
chr5_-_150473127 0.21 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr17_+_40118805 0.21 ENST00000591072.1
ENST00000587679.1
ENST00000393888.1
ENST00000441615.2
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr12_+_7053228 0.20 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr7_+_79763271 0.20 ENST00000442586.1
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr5_-_177580855 0.20 ENST00000514354.1
ENST00000511078.1
NHP2
NHP2 ribonucleoprotein
chr7_+_141478242 0.20 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr19_+_19144384 0.20 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
ARMC6
armadillo repeat containing 6
chr14_+_89029323 0.20 ENST00000554602.1
ZC3H14
zinc finger CCCH-type containing 14
chr6_-_27782548 0.20 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr12_-_116714564 0.20 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr1_-_3566627 0.20 ENST00000419924.2
ENST00000270708.7
WRAP73
WD repeat containing, antisense to TP73
chr11_-_568369 0.20 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG
MIR210 host gene (non-protein coding)
chr4_+_5526883 0.19 ENST00000195455.2
C4orf6
chromosome 4 open reading frame 6
chr15_-_41522889 0.19 ENST00000458580.2
ENST00000314992.5
ENST00000558396.1
EXD1
exonuclease 3'-5' domain containing 1
chr10_+_81891416 0.19 ENST00000372270.2
PLAC9
placenta-specific 9
chr10_+_24528108 0.19 ENST00000438429.1
KIAA1217
KIAA1217
chr3_-_87039662 0.19 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr11_+_102188224 0.19 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr1_-_153348067 0.19 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chr1_+_15272271 0.19 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr12_-_86650077 0.19 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr5_-_141030943 0.19 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1
FCH and double SH3 domains 1
chr1_+_92545862 0.19 ENST00000370382.3
ENST00000342818.3
BTBD8
BTB (POZ) domain containing 8
chr19_-_893200 0.19 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
MED16
mediator complex subunit 16
chr5_+_132009675 0.19 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4
chr1_-_198906528 0.18 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr17_+_45908974 0.18 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr6_-_26124138 0.18 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr11_+_102188272 0.17 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr2_+_66918558 0.17 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr16_-_75285380 0.17 ENST00000393420.6
ENST00000162330.5
BCAR1
breast cancer anti-estrogen resistance 1
chr19_-_3971050 0.17 ENST00000545797.2
ENST00000596311.1
DAPK3
death-associated protein kinase 3
chr13_-_43566301 0.17 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chr7_-_3083472 0.17 ENST00000356408.3
CARD11
caspase recruitment domain family, member 11
chrX_+_154114635 0.17 ENST00000369446.2
F8A1
coagulation factor VIII-associated 1
chrX_+_36053908 0.17 ENST00000378660.2
CHDC2
calponin homology domain containing 2
chr12_-_10978957 0.17 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr1_-_6052463 0.17 ENST00000378156.4
NPHP4
nephronophthisis 4
chr6_-_11232891 0.17 ENST00000379433.5
ENST00000379446.5
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr6_-_29527702 0.17 ENST00000377050.4
UBD
ubiquitin D
chr5_-_177580777 0.16 ENST00000314397.4
NHP2
NHP2 ribonucleoprotein
chr1_+_188874798 0.16 ENST00000445072.1
LINC01035
long intergenic non-protein coding RNA 1035
chr18_+_1099004 0.16 ENST00000581556.1
RP11-78F17.1
RP11-78F17.1
chr11_-_62609281 0.16 ENST00000525239.1
ENST00000538098.2
WDR74
WD repeat domain 74
chr17_-_15501932 0.16 ENST00000583965.1
CDRT1
CMT1A duplicated region transcript 1
chr18_+_63417864 0.16 ENST00000536984.2
CDH7
cadherin 7, type 2
chr8_-_125577940 0.16 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr14_+_104177607 0.16 ENST00000429169.1
AL049840.1
Uncharacterized protein; cDNA FLJ53535
chr12_+_78359999 0.16 ENST00000550503.1
NAV3
neuron navigator 3
chr1_-_2458026 0.16 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chr16_+_4666475 0.16 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr10_+_52094298 0.16 ENST00000595931.1
AC069547.1
HCG1745369; PRO3073; Uncharacterized protein
chrX_+_107288280 0.16 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr19_+_39903185 0.15 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr19_+_50094866 0.15 ENST00000418929.2
PRR12
proline rich 12
chr16_+_4845379 0.15 ENST00000588606.1
ENST00000586005.1
SMIM22
small integral membrane protein 22
chr12_+_93096759 0.15 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr14_+_55033815 0.15 ENST00000554335.1
SAMD4A
sterile alpha motif domain containing 4A
chr4_-_144826682 0.15 ENST00000358615.4
ENST00000437468.2
GYPE
glycophorin E (MNS blood group)
chr3_+_157261116 0.15 ENST00000468043.1
ENST00000459838.1
ENST00000461040.1
ENST00000449199.2
ENST00000426338.2
C3orf55
chromosome 3 open reading frame 55
chr12_-_58212487 0.15 ENST00000549994.1
AVIL
advillin
chr15_-_65117807 0.15 ENST00000559239.1
ENST00000268043.4
ENST00000333425.6
PIF1
PIF1 5'-to-3' DNA helicase
chr9_+_35658262 0.15 ENST00000378407.3
ENST00000378406.1
ENST00000426546.2
ENST00000327351.2
ENST00000421582.2
CCDC107
coiled-coil domain containing 107
chr3_-_192445289 0.15 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr9_-_35080013 0.15 ENST00000378643.3
FANCG
Fanconi anemia, complementation group G
chr1_-_209792111 0.15 ENST00000455193.1
LAMB3
laminin, beta 3
chr11_+_64085560 0.14 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
PRDX5
peroxiredoxin 5
chr15_+_65337708 0.14 ENST00000334287.2
SLC51B
solute carrier family 51, beta subunit
chr11_-_105010320 0.14 ENST00000532895.1
ENST00000530950.1
CARD18
caspase recruitment domain family, member 18
chr19_+_12175596 0.14 ENST00000441304.2
ZNF844
zinc finger protein 844
chr11_+_111782934 0.14 ENST00000304298.3
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr9_-_117880477 0.14 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
TNC
tenascin C
chr16_+_90089008 0.14 ENST00000268699.4
GAS8
growth arrest-specific 8
chr15_+_41245160 0.14 ENST00000444189.2
ENST00000446533.3
CHAC1
ChaC, cation transport regulator homolog 1 (E. coli)
chr14_+_65007177 0.14 ENST00000247207.6
HSPA2
heat shock 70kDa protein 2
chr5_-_147162078 0.14 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr12_+_49621658 0.13 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr19_+_3572925 0.13 ENST00000333651.6
ENST00000417382.1
ENST00000453933.1
ENST00000262949.7
HMG20B
high mobility group 20B
chr1_-_149783914 0.13 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF
histone cluster 2, H2bf
chr2_+_28618532 0.13 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr10_+_106113515 0.13 ENST00000369704.3
ENST00000312902.5
CCDC147
coiled-coil domain containing 147
chr17_+_36858694 0.13 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr9_+_132099158 0.13 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr8_+_7752151 0.13 ENST00000302247.2
DEFB4A
defensin, beta 4A
chr15_+_45406519 0.13 ENST00000323030.5
DUOXA2
dual oxidase maturation factor 2
chr8_-_23282820 0.13 ENST00000520871.1
LOXL2
lysyl oxidase-like 2
chr12_-_106697974 0.13 ENST00000553039.1
CKAP4
cytoskeleton-associated protein 4
chr19_-_18314799 0.13 ENST00000481914.2
RAB3A
RAB3A, member RAS oncogene family
chr4_+_154622652 0.13 ENST00000260010.6
TLR2
toll-like receptor 2
chr19_+_45445524 0.13 ENST00000591600.1
APOC4
apolipoprotein C-IV
chrX_+_154611749 0.13 ENST00000369505.3
F8A2
coagulation factor VIII-associated 2
chr1_-_206306107 0.13 ENST00000436158.1
ENST00000455672.1
RP11-38J22.6
RP11-38J22.6
chr19_-_4065730 0.13 ENST00000601588.1
ZBTB7A
zinc finger and BTB domain containing 7A
chr20_+_33292068 0.13 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr6_+_131958436 0.13 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chrX_-_24665353 0.12 ENST00000379144.2
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr5_-_177580933 0.12 ENST00000274606.3
NHP2
NHP2 ribonucleoprotein
chr6_+_46761118 0.12 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr12_+_133707204 0.12 ENST00000426665.2
ZNF10
zinc finger protein 10
chr17_-_4852332 0.12 ENST00000572383.1
PFN1
profilin 1
chr5_-_13944652 0.12 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr19_-_19144243 0.12 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SUGP2
SURP and G patch domain containing 2
chr8_+_107593198 0.12 ENST00000517686.1
OXR1
oxidation resistance 1

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 0.8 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.5 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.5 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 7.5 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.3 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.1 0.3 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.4 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.2 GO:0050975 sensory perception of touch(GO:0050975) maintenance of synapse structure(GO:0099558) presynaptic active zone organization(GO:1990709)
0.1 0.8 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.1 0.2 GO:0070668 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.3 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.2 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.1 0.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.2 GO:0018277 protein deamination(GO:0018277)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.2 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 2.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.4 GO:0042756 drinking behavior(GO:0042756)
0.0 0.0 GO:0060775 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.1 GO:0061145 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.2 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.3 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.1 GO:0052360 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.4 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.5 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:1990619 positive regulation of chondrocyte proliferation(GO:1902732) histone H3-K9 deacetylation(GO:1990619)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0042335 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.3 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.3 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.2 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.1 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:1903367 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 1.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.1 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.0 GO:0061183 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 0.1 GO:1903770 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.0 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.0 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.2 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.0 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.4 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.0 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.0 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.1 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.0 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.0 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.5 GO:0001533 cornified envelope(GO:0001533)
0.1 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.5 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.2 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.4 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 2.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.0 GO:0009346 citrate lyase complex(GO:0009346)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.0 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.2 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.3 GO:0034711 inhibin binding(GO:0034711)
0.1 0.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 3.4 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.0 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.0 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.0 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0047888 fatty acid peroxidase activity(GO:0047888)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 4.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)