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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PPARA

Z-value: 1.07

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Transcription factors associated with PPARA

Gene Symbol Gene ID Gene Info
PPARA
ENSG00000186951.12 peroxisome proliferator activated receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PPARAhg19_v2_chr22_+_46546406_465464550.612.0e-01Click!

Activity profile of PPARA motif

Sorted Z-values of PPARA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_103046954 0.98 ENST00000606448.1
FGF14-AS2
FGF14 antisense RNA 2
chr1_+_222988363 0.68 ENST00000450784.1
ENST00000426045.1
ENST00000457955.1
ENST00000444858.1
ENST00000435378.1
ENST00000441676.1
RP11-452F19.3
RP11-452F19.3
chr14_+_76776957 0.62 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr5_-_126409159 0.57 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr8_-_144651024 0.57 ENST00000524906.1
ENST00000532862.1
ENST00000534459.1
MROH6
maestro heat-like repeat family member 6
chr16_-_3422283 0.54 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr15_+_23810903 0.54 ENST00000564592.1
MKRN3
makorin ring finger protein 3
chr16_+_67563250 0.54 ENST00000566907.1
FAM65A
family with sequence similarity 65, member A
chr1_+_222988406 0.53 ENST00000448808.1
ENST00000457636.1
ENST00000439440.1
RP11-452F19.3
RP11-452F19.3
chr16_+_777739 0.51 ENST00000563792.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr14_+_38065052 0.47 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr17_-_70417365 0.47 ENST00000580948.1
LINC00511
long intergenic non-protein coding RNA 511
chr22_+_22676808 0.47 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr22_+_23264766 0.46 ENST00000390331.2
IGLC7
immunoglobulin lambda constant 7
chrX_-_108868390 0.46 ENST00000372101.2
KCNE1L
KCNE1-like
chr3_-_123339343 0.43 ENST00000578202.1
MYLK
myosin light chain kinase
chr3_-_123339418 0.42 ENST00000583087.1
MYLK
myosin light chain kinase
chr3_-_113464906 0.42 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_+_219745020 0.41 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr11_+_66624527 0.40 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr15_+_76352178 0.40 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr15_+_71145578 0.40 ENST00000544974.2
ENST00000558546.1
LRRC49
leucine rich repeat containing 49
chr1_-_152061537 0.40 ENST00000368806.1
TCHHL1
trichohyalin-like 1
chrX_-_55208866 0.40 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr14_-_54418598 0.39 ENST00000609748.1
ENST00000558961.1
BMP4
bone morphogenetic protein 4
chr1_+_184020830 0.39 ENST00000533373.1
ENST00000423085.2
TSEN15
TSEN15 tRNA splicing endonuclease subunit
chr8_-_53626974 0.38 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr2_-_25194476 0.38 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr3_-_45957534 0.37 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr5_+_162887556 0.37 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR
hyaluronan-mediated motility receptor (RHAMM)
chr19_+_2977444 0.36 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr3_+_46449049 0.36 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2
chemokine (C-C motif) receptor-like 2
chr20_-_42816206 0.36 ENST00000372980.3
JPH2
junctophilin 2
chr19_-_49140692 0.35 ENST00000222122.5
DBP
D site of albumin promoter (albumin D-box) binding protein
chr6_+_90272488 0.35 ENST00000485637.1
ENST00000522705.1
ANKRD6
ankyrin repeat domain 6
chr5_-_42811986 0.35 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr1_+_184020811 0.34 ENST00000361641.1
TSEN15
TSEN15 tRNA splicing endonuclease subunit
chr4_+_30721968 0.34 ENST00000361762.2
PCDH7
protocadherin 7
chr2_-_165698662 0.34 ENST00000194871.6
ENST00000445474.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr6_+_108616243 0.33 ENST00000421954.1
LACE1
lactation elevated 1
chr8_-_64080945 0.33 ENST00000603538.1
YTHDF3-AS1
YTHDF3 antisense RNA 1 (head to head)
chr5_-_79287060 0.33 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
MTX3
metaxin 3
chr2_+_97454321 0.33 ENST00000540067.1
CNNM4
cyclin M4
chr15_-_72767490 0.32 ENST00000565181.1
RP11-1007O24.3
RP11-1007O24.3
chr8_+_125486939 0.32 ENST00000303545.3
RNF139
ring finger protein 139
chr17_+_7123207 0.32 ENST00000584103.1
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase, very long chain
chr1_-_91487770 0.31 ENST00000337393.5
ZNF644
zinc finger protein 644
chr10_-_33625154 0.31 ENST00000265371.4
NRP1
neuropilin 1
chr3_-_45957088 0.31 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr11_+_12108410 0.31 ENST00000527997.1
RP13-631K18.5
RP13-631K18.5
chr10_-_105156198 0.31 ENST00000369815.1
ENST00000309579.3
ENST00000337003.4
USMG5
up-regulated during skeletal muscle growth 5 homolog (mouse)
chr3_-_113465065 0.31 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr11_+_86748957 0.31 ENST00000526733.1
ENST00000532959.1
TMEM135
transmembrane protein 135
chr1_-_211752073 0.30 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr7_-_32931623 0.30 ENST00000452926.1
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr5_+_139055055 0.30 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr12_-_15865844 0.30 ENST00000543612.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr1_+_222988464 0.30 ENST00000420335.1
RP11-452F19.3
RP11-452F19.3
chr12_+_25348186 0.30 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYRM5
LYR motif containing 5
chr17_+_48610074 0.29 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chr18_-_19284724 0.29 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr6_+_149068464 0.29 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr11_-_66103932 0.29 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr5_-_42812143 0.29 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr3_-_50605077 0.29 ENST00000426034.1
ENST00000441239.1
C3orf18
chromosome 3 open reading frame 18
chr4_+_24797085 0.29 ENST00000382120.3
SOD3
superoxide dismutase 3, extracellular
chr10_-_16563870 0.29 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr15_+_49715449 0.28 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr11_+_86748863 0.28 ENST00000340353.7
TMEM135
transmembrane protein 135
chr1_-_12679171 0.28 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr8_+_97597148 0.28 ENST00000521590.1
SDC2
syndecan 2
chr11_+_86749035 0.28 ENST00000305494.5
ENST00000535167.1
TMEM135
transmembrane protein 135
chr2_-_177502659 0.28 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr14_-_58893876 0.28 ENST00000555097.1
ENST00000555404.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr2_-_165698521 0.27 ENST00000409184.3
ENST00000392717.2
ENST00000456693.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr4_-_159094194 0.27 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr2_+_171034646 0.27 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr7_+_79764104 0.27 ENST00000351004.3
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr13_+_51913819 0.27 ENST00000419898.2
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr11_-_119249805 0.27 ENST00000527843.1
USP2
ubiquitin specific peptidase 2
chr4_+_41614909 0.27 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr2_-_201936302 0.27 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B
family with sequence similarity 126, member B
chr11_+_86502085 0.27 ENST00000527521.1
PRSS23
protease, serine, 23
chr19_-_4517613 0.26 ENST00000301286.3
PLIN4
perilipin 4
chr5_-_140027175 0.26 ENST00000512088.1
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr9_-_88874519 0.26 ENST00000376001.3
ENST00000339137.3
C9orf153
chromosome 9 open reading frame 153
chr3_+_179322481 0.26 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr4_-_40632757 0.26 ENST00000511902.1
ENST00000505220.1
RBM47
RNA binding motif protein 47
chr4_+_11627248 0.26 ENST00000510095.1
RP11-281P23.2
RP11-281P23.2
chr1_-_27709793 0.26 ENST00000374027.3
ENST00000374025.3
CD164L2
CD164 sialomucin-like 2
chr19_+_17579556 0.25 ENST00000442725.1
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr1_-_85156216 0.25 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr6_+_35227449 0.25 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
ZNF76
zinc finger protein 76
chr1_-_11907829 0.25 ENST00000376480.3
NPPA
natriuretic peptide A
chr14_-_102976135 0.25 ENST00000560748.1
ANKRD9
ankyrin repeat domain 9
chr15_+_82555125 0.25 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B
family with sequence similarity 154, member B
chr1_+_36024107 0.25 ENST00000437806.1
NCDN
neurochondrin
chr7_-_91875358 0.25 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1
KRIT1, ankyrin repeat containing
chr6_+_89790490 0.25 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr5_+_133451254 0.25 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr2_-_99871570 0.24 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr17_-_4806369 0.24 ENST00000293780.4
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
chr10_-_65028817 0.24 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr19_-_55669093 0.24 ENST00000344887.5
TNNI3
troponin I type 3 (cardiac)
chr14_+_37126765 0.24 ENST00000402703.2
PAX9
paired box 9
chr19_+_16771936 0.24 ENST00000187762.2
ENST00000599479.1
TMEM38A
transmembrane protein 38A
chr17_+_38975358 0.24 ENST00000436612.1
ENST00000301665.3
TMEM99
transmembrane protein 99
chr5_+_139927213 0.24 ENST00000310331.2
EIF4EBP3
eukaryotic translation initiation factor 4E binding protein 3
chrX_+_152990302 0.23 ENST00000218104.3
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr15_-_44487408 0.23 ENST00000402883.1
ENST00000417257.1
FRMD5
FERM domain containing 5
chr11_-_1783633 0.23 ENST00000367196.3
CTSD
cathepsin D
chr11_-_117170403 0.23 ENST00000504995.1
BACE1
beta-site APP-cleaving enzyme 1
chr2_+_220309379 0.23 ENST00000451076.1
SPEG
SPEG complex locus
chr1_-_27709816 0.23 ENST00000374030.1
CD164L2
CD164 sialomucin-like 2
chr17_+_48609903 0.23 ENST00000268933.3
EPN3
epsin 3
chr1_-_85156417 0.23 ENST00000422026.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr11_+_111169565 0.23 ENST00000528846.1
COLCA2
colorectal cancer associated 2
chrX_-_109683446 0.23 ENST00000372057.1
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr17_+_48046538 0.23 ENST00000240306.3
DLX4
distal-less homeobox 4
chr21_-_30365136 0.23 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr11_+_1860682 0.22 ENST00000381906.1
TNNI2
troponin I type 2 (skeletal, fast)
chr10_+_22605374 0.22 ENST00000448361.1
COMMD3
COMM domain containing 3
chrX_-_151619746 0.22 ENST00000370314.4
GABRA3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr4_+_26322409 0.22 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr19_-_33360647 0.22 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
SLC7A9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr4_+_106067943 0.21 ENST00000380013.4
ENST00000394764.1
ENST00000413648.2
TET2
tet methylcytosine dioxygenase 2
chr3_+_179322573 0.21 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr14_-_104387831 0.21 ENST00000557040.1
ENST00000414262.2
ENST00000555030.1
ENST00000554713.1
ENST00000553430.1
C14orf2
chromosome 14 open reading frame 2
chr2_-_214014959 0.21 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
IKZF2
IKAROS family zinc finger 2 (Helios)
chr2_-_287299 0.21 ENST00000405290.1
FAM150B
family with sequence similarity 150, member B
chr6_+_89790459 0.21 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr7_+_79765071 0.21 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr17_-_73505961 0.21 ENST00000433559.2
CASKIN2
CASK interacting protein 2
chr5_+_133562095 0.21 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr4_+_30723003 0.21 ENST00000543491.1
PCDH7
protocadherin 7
chr7_-_91875109 0.21 ENST00000412043.2
ENST00000430102.1
ENST00000425073.1
ENST00000394503.2
ENST00000454017.1
ENST00000440209.1
ENST00000413688.1
ENST00000452773.1
ENST00000433016.1
ENST00000394505.2
ENST00000422347.1
ENST00000458493.1
ENST00000425919.1
KRIT1
KRIT1, ankyrin repeat containing
chr8_-_144886321 0.21 ENST00000526832.1
SCRIB
scribbled planar cell polarity protein
chr5_+_112849373 0.21 ENST00000161863.4
ENST00000515883.1
YTHDC2
YTH domain containing 2
chr10_-_119806085 0.21 ENST00000355624.3
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr18_-_59561417 0.21 ENST00000591306.1
RNF152
ring finger protein 152
chr2_+_220299547 0.21 ENST00000312358.7
SPEG
SPEG complex locus
chr1_-_204183071 0.21 ENST00000308302.3
GOLT1A
golgi transport 1A
chr8_-_18666360 0.21 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chr4_-_13485937 0.21 ENST00000330852.5
ENST00000288723.4
ENST00000338176.4
RAB28
RAB28, member RAS oncogene family
chr3_-_42845922 0.20 ENST00000452906.2
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr2_-_178257401 0.20 ENST00000464747.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr12_-_46121554 0.20 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chrX_-_135849484 0.20 ENST00000370620.1
ENST00000535227.1
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr7_+_121513143 0.20 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr1_+_155583012 0.20 ENST00000462250.2
MSTO1
misato 1, mitochondrial distribution and morphology regulator
chr12_+_121163538 0.20 ENST00000242592.4
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr2_+_230787213 0.20 ENST00000409992.1
FBXO36
F-box protein 36
chr2_+_166430619 0.20 ENST00000409420.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr14_-_73360796 0.20 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr12_-_109797249 0.20 ENST00000538041.1
RP11-256L11.1
RP11-256L11.1
chr9_-_96215822 0.20 ENST00000375412.5
FAM120AOS
family with sequence similarity 120A opposite strand
chr15_+_43809797 0.20 ENST00000399453.1
ENST00000300231.5
MAP1A
microtubule-associated protein 1A
chr1_-_211848899 0.20 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NEK2
NIMA-related kinase 2
chr3_-_49726104 0.20 ENST00000383728.3
ENST00000545762.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr8_+_96037255 0.20 ENST00000286687.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr10_-_76995675 0.19 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr19_-_46285646 0.19 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr1_-_85040090 0.19 ENST00000370630.5
CTBS
chitobiase, di-N-acetyl-
chr11_-_111783595 0.19 ENST00000528628.1
CRYAB
crystallin, alpha B
chr17_+_43213004 0.19 ENST00000586346.1
ENST00000398322.3
ENST00000592162.1
ENST00000376955.4
ENST00000321854.8
ACBD4
acyl-CoA binding domain containing 4
chr12_+_54378849 0.19 ENST00000515593.1
HOXC10
homeobox C10
chr2_+_30670077 0.19 ENST00000466477.1
ENST00000465200.1
ENST00000379509.3
ENST00000319406.4
ENST00000488144.1
ENST00000465538.1
ENST00000309052.4
ENST00000359433.1
LCLAT1
lysocardiolipin acyltransferase 1
chr22_-_39239987 0.19 ENST00000333039.2
NPTXR
neuronal pentraxin receptor
chr13_+_32605437 0.19 ENST00000380250.3
FRY
furry homolog (Drosophila)
chr2_-_235405168 0.19 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr19_-_11639910 0.19 ENST00000588998.1
ENST00000586149.1
ECSIT
ECSIT signalling integrator
chr22_+_21321531 0.19 ENST00000405089.1
ENST00000335375.5
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr14_-_74226961 0.19 ENST00000286523.5
ENST00000435371.1
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chr1_-_8586084 0.19 ENST00000464972.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr16_+_776936 0.19 ENST00000549114.1
ENST00000341413.4
ENST00000562187.1
ENST00000564537.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr5_-_162887054 0.19 ENST00000517501.1
NUDCD2
NudC domain containing 2
chr10_+_94050913 0.19 ENST00000358935.2
MARCH5
membrane-associated ring finger (C3HC4) 5
chr3_-_9994021 0.18 ENST00000411976.2
ENST00000412055.1
PRRT3
proline-rich transmembrane protein 3
chr5_-_139930713 0.18 ENST00000602657.1
SRA1
steroid receptor RNA activator 1
chr11_-_790060 0.18 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1
chr1_+_202317815 0.18 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr6_+_170102210 0.18 ENST00000439249.1
ENST00000332290.2
C6orf120
chromosome 6 open reading frame 120
chr12_+_2921788 0.18 ENST00000228799.2
ENST00000419778.2
ENST00000542548.1
ITFG2
integrin alpha FG-GAP repeat containing 2
chr3_+_37284824 0.18 ENST00000431105.1
GOLGA4
golgin A4
chr16_-_28937027 0.18 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr17_+_38219063 0.18 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
THRA
thyroid hormone receptor, alpha
chr19_-_11308190 0.18 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2
KN motif and ankyrin repeat domains 2
chr4_+_41614720 0.18 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr15_+_49715293 0.18 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr12_-_95467267 0.17 ENST00000330677.7
NR2C1
nuclear receptor subfamily 2, group C, member 1
chr20_+_36661910 0.17 ENST00000373433.4
RPRD1B
regulation of nuclear pre-mRNA domain containing 1B
chr12_+_121837905 0.17 ENST00000392465.3
ENST00000554606.1
ENST00000392464.2
ENST00000555076.1
RNF34
ring finger protein 34, E3 ubiquitin protein ligase
chr3_-_122102065 0.17 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
CCDC58
coiled-coil domain containing 58
chr11_+_65190245 0.17 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr17_-_30470154 0.17 ENST00000398832.2
AC090616.2
Uncharacterized protein
chr2_+_103378472 0.17 ENST00000412401.2
TMEM182
transmembrane protein 182
chr2_+_178257372 0.17 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chrX_-_119694538 0.17 ENST00000371322.5
CUL4B
cullin 4B
chr7_+_116165754 0.17 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr9_-_72374848 0.17 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
PTAR1
protein prenyltransferase alpha subunit repeat containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.6 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.5 GO:0060437 lung growth(GO:0060437)
0.1 0.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.4 GO:0048391 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.2 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.5 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.4 GO:0030421 defecation(GO:0030421)
0.1 0.2 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.1 0.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.3 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.3 GO:1905040 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) sensory neuron axon guidance(GO:0097374) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.7 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.2 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.2 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.4 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1 0.2 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.3 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.2 GO:0060460 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.4 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0042335 cuticle development(GO:0042335)
0.0 0.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.6 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.6 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.5 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:0006477 protein sulfation(GO:0006477)
0.0 0.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.1 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.0 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.0 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.0 0.2 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.3 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.5 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.4 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.3 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 1.2 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.4 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.5 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.3 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.4 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.3 GO:0044839 G2/M transition of mitotic cell cycle(GO:0000086) cell cycle G2/M phase transition(GO:0044839)
0.0 0.2 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0061525 hindgut development(GO:0061525)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.0 GO:1904247 modification by virus of host mRNA processing(GO:0046778) regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.0 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.0 GO:0060032 notochord regression(GO:0060032)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.0 GO:1901899 positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.3 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.2 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.0 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.0 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0031415 NatA complex(GO:0031415)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.2 GO:0072534 perineuronal net(GO:0072534)
0.0 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1990175 EH domain binding(GO:1990175)
0.1 0.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.5 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.2 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.2 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0098821 activin receptor activity, type I(GO:0016361) BMP receptor activity(GO:0098821)
0.0 0.1 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.2 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.0 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.5 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887) thyroid hormone binding(GO:0070324)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.0 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.6 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis