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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RAD21_SMC3

Z-value: 1.02

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Transcription factors associated with RAD21_SMC3

Gene Symbol Gene ID Gene Info
RAD21
ENSG00000164754.8 RAD21 cohesin complex component
SMC3
ENSG00000108055.9 structural maintenance of chromosomes 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMC3hg19_v2_chr10_+_112327425_112327516-0.853.3e-02Click!
RAD21hg19_v2_chr8_-_117886732_117886767-0.796.1e-02Click!

Activity profile of RAD21_SMC3 motif

Sorted Z-values of RAD21_SMC3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_45722727 1.93 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr2_+_114737472 1.41 ENST00000420161.1
AC110769.3
AC110769.3
chr6_+_138188551 1.38 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_+_37940153 1.30 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr6_+_138188351 1.27 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr14_+_24630465 1.20 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
IRF9
interferon regulatory factor 9
chr6_+_138188378 1.19 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr12_-_7245125 1.12 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr5_-_139726181 1.10 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr12_-_58159361 0.94 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr12_-_7245018 0.92 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr18_-_26941900 0.91 ENST00000577674.1
CTD-2515C13.2
CTD-2515C13.2
chr2_+_228678550 0.89 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr11_+_118826999 0.87 ENST00000264031.2
UPK2
uroplakin 2
chr12_-_7245080 0.85 ENST00000541042.1
ENST00000540242.1
C1R
complement component 1, r subcomponent
chr10_+_104154229 0.79 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr14_+_52118694 0.73 ENST00000554778.1
FRMD6
FERM domain containing 6
chr8_-_11873043 0.67 ENST00000527396.1
RP11-481A20.11
Protein LOC101060662
chr2_+_27309605 0.66 ENST00000260599.6
ENST00000260598.5
ENST00000429697.1
KHK
ketohexokinase (fructokinase)
chr12_-_7245152 0.65 ENST00000542220.2
C1R
complement component 1, r subcomponent
chr15_-_38856836 0.64 ENST00000450598.2
ENST00000559830.1
ENST00000558164.1
ENST00000310803.5
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr9_+_71650645 0.60 ENST00000396366.2
FXN
frataxin
chr1_-_146989697 0.57 ENST00000437831.1
LINC00624
long intergenic non-protein coding RNA 624
chr17_-_48277552 0.52 ENST00000507689.1
COL1A1
collagen, type I, alpha 1
chr15_-_34502197 0.52 ENST00000557877.1
KATNBL1
katanin p80 subunit B-like 1
chr17_+_76356516 0.52 ENST00000592569.1
RP11-806H10.4
RP11-806H10.4
chr16_-_22012419 0.46 ENST00000537222.2
ENST00000424898.2
ENST00000286143.6
PDZD9
PDZ domain containing 9
chr7_-_45957011 0.45 ENST00000417621.1
IGFBP3
insulin-like growth factor binding protein 3
chr14_-_23292596 0.44 ENST00000554741.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_-_26220366 0.43 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr19_-_55652290 0.43 ENST00000589745.1
TNNT1
troponin T type 1 (skeletal, slow)
chr12_-_82752159 0.43 ENST00000552377.1
CCDC59
coiled-coil domain containing 59
chr1_+_840205 0.43 ENST00000607769.1
RP11-54O7.16
RP11-54O7.16
chr8_+_24772455 0.39 ENST00000433454.2
NEFM
neurofilament, medium polypeptide
chr7_-_45956856 0.39 ENST00000428530.1
IGFBP3
insulin-like growth factor binding protein 3
chr16_+_66638685 0.37 ENST00000565003.1
CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr9_+_131901710 0.36 ENST00000524946.2
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr20_+_48807351 0.36 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr9_+_116917807 0.35 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr11_+_73675873 0.34 ENST00000537753.1
ENST00000542350.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr1_+_16767195 0.34 ENST00000504551.2
ENST00000457722.2
ENST00000406746.1
ENST00000443980.2
NECAP2
NECAP endocytosis associated 2
chr7_-_6388389 0.34 ENST00000578372.1
FAM220A
family with sequence similarity 220, member A
chr1_-_63782888 0.34 ENST00000436475.2
LINC00466
long intergenic non-protein coding RNA 466
chr9_+_103189458 0.33 ENST00000398977.2
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr1_+_16767167 0.33 ENST00000337132.5
NECAP2
NECAP endocytosis associated 2
chr3_+_9774164 0.33 ENST00000426583.1
BRPF1
bromodomain and PHD finger containing, 1
chr5_+_172571445 0.33 ENST00000231668.9
ENST00000351486.5
ENST00000352523.6
ENST00000393770.4
BNIP1
BCL2/adenovirus E1B 19kDa interacting protein 1
chr1_-_8075693 0.32 ENST00000467067.1
ERRFI1
ERBB receptor feedback inhibitor 1
chr2_-_220025263 0.32 ENST00000457600.1
NHEJ1
nonhomologous end-joining factor 1
chr11_+_120039685 0.32 ENST00000530303.1
ENST00000319763.1
AP000679.2
Uncharacterized protein
chr16_-_90085824 0.31 ENST00000002501.6
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr12_+_58176525 0.31 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr17_+_41561317 0.31 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
DHX8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chrX_+_23801280 0.31 ENST00000379251.3
ENST00000379253.3
ENST00000379254.1
ENST00000379270.4
SAT1
spermidine/spermine N1-acetyltransferase 1
chr6_-_44225231 0.31 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
SLC35B2
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr2_+_113342011 0.31 ENST00000324913.5
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr17_+_7591639 0.30 ENST00000396463.2
WRAP53
WD repeat containing, antisense to TP53
chr16_+_22308717 0.30 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
POLR3E
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr1_+_212208919 0.30 ENST00000366991.4
ENST00000542077.1
DTL
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr10_+_81107216 0.29 ENST00000394579.3
ENST00000225174.3
PPIF
peptidylprolyl isomerase F
chr7_-_5569588 0.29 ENST00000417101.1
ACTB
actin, beta
chr20_-_34542548 0.29 ENST00000305978.2
SCAND1
SCAN domain containing 1
chr19_-_55653259 0.29 ENST00000593194.1
TNNT1
troponin T type 1 (skeletal, slow)
chr1_-_35325400 0.29 ENST00000521580.2
SMIM12
small integral membrane protein 12
chr6_+_31105426 0.29 ENST00000547221.1
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr11_-_407103 0.28 ENST00000526395.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr17_+_48556158 0.28 ENST00000258955.2
RSAD1
radical S-adenosyl methionine domain containing 1
chr20_-_1447467 0.27 ENST00000353088.2
ENST00000350991.4
NSFL1C
NSFL1 (p97) cofactor (p47)
chr19_-_49496557 0.27 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1
glycogen synthase 1 (muscle)
chr19_+_49496782 0.27 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr21_+_42741979 0.26 ENST00000543692.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr17_-_7518145 0.26 ENST00000250113.7
ENST00000571597.1
FXR2
fragile X mental retardation, autosomal homolog 2
chr14_-_75079026 0.26 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2
chr8_-_11325047 0.26 ENST00000531804.1
FAM167A
family with sequence similarity 167, member A
chr15_+_75074410 0.26 ENST00000439220.2
CSK
c-src tyrosine kinase
chr11_+_44117219 0.25 ENST00000532479.1
ENST00000527014.1
EXT2
exostosin glycosyltransferase 2
chr16_+_2255447 0.25 ENST00000562352.1
ENST00000562479.1
ENST00000301724.10
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr19_+_45690646 0.25 ENST00000591569.1
AC006126.3
Uncharacterized protein
chr17_+_38137073 0.25 ENST00000541736.1
PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr19_+_49496705 0.25 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr3_-_50340996 0.24 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr16_-_2390704 0.24 ENST00000301732.5
ENST00000382381.3
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr9_+_103189405 0.24 ENST00000395067.2
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr7_-_99679324 0.24 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
ZNF3
zinc finger protein 3
chr22_-_19132154 0.24 ENST00000252137.6
DGCR14
DiGeorge syndrome critical region gene 14
chr11_+_60691924 0.23 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A
transmembrane protein 132A
chr1_+_28844778 0.23 ENST00000411533.1
RCC1
regulator of chromosome condensation 1
chr17_-_1090599 0.23 ENST00000544583.2
ABR
active BCR-related
chr2_-_128643496 0.23 ENST00000272647.5
AMMECR1L
AMMECR1-like
chr9_+_130965651 0.23 ENST00000475805.1
ENST00000341179.7
ENST00000372923.3
DNM1
dynamin 1
chr19_-_3547305 0.23 ENST00000589063.1
MFSD12
major facilitator superfamily domain containing 12
chr19_-_36001386 0.23 ENST00000461300.1
DMKN
dermokine
chr12_-_113573495 0.22 ENST00000446861.3
RASAL1
RAS protein activator like 1 (GAP1 like)
chr10_-_6622258 0.22 ENST00000263125.5
PRKCQ
protein kinase C, theta
chr16_-_19897455 0.22 ENST00000568214.1
ENST00000569479.1
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chrX_+_49020121 0.22 ENST00000415364.1
ENST00000376338.3
ENST00000425285.1
MAGIX
MAGI family member, X-linked
chr20_-_1447547 0.22 ENST00000476071.1
NSFL1C
NSFL1 (p97) cofactor (p47)
chr20_-_30311703 0.22 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2L1
BCL2-like 1
chr17_-_19265855 0.22 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9D1
B9 protein domain 1
chr7_-_27219632 0.22 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr16_+_75032901 0.21 ENST00000335325.4
ENST00000320619.6
ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr10_-_6622201 0.21 ENST00000539722.1
ENST00000397176.2
PRKCQ
protein kinase C, theta
chr7_-_91509972 0.21 ENST00000425936.1
MTERF
mitochondrial transcription termination factor
chr4_+_7045042 0.21 ENST00000310074.7
ENST00000512388.1
TADA2B
transcriptional adaptor 2B
chr19_-_6481776 0.21 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C
DENN/MADD domain containing 1C
chr10_-_49732281 0.21 ENST00000374170.1
ARHGAP22
Rho GTPase activating protein 22
chr10_-_15413035 0.21 ENST00000378116.4
ENST00000455654.1
FAM171A1
family with sequence similarity 171, member A1
chr15_-_40212363 0.21 ENST00000299092.3
GPR176
G protein-coupled receptor 176
chr22_+_22764088 0.21 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr12_-_95510743 0.21 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr19_-_1876156 0.21 ENST00000565797.1
CTB-31O20.2
CTB-31O20.2
chr11_+_73000449 0.20 ENST00000535931.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr10_+_12391685 0.19 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr19_+_16222678 0.19 ENST00000586682.1
RAB8A
RAB8A, member RAS oncogene family
chr17_-_8286484 0.19 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
RPL26
ribosomal protein L26
chr8_-_145550571 0.19 ENST00000332324.4
DGAT1
diacylglycerol O-acyltransferase 1
chr9_-_38069208 0.19 ENST00000377707.3
ENST00000377700.4
SHB
Src homology 2 domain containing adaptor protein B
chr1_+_20208870 0.19 ENST00000375120.3
OTUD3
OTU domain containing 3
chr8_+_42948641 0.19 ENST00000518991.1
ENST00000331373.5
POMK
protein-O-mannose kinase
chr12_-_51663728 0.19 ENST00000603864.1
ENST00000605426.1
SMAGP
small cell adhesion glycoprotein
chr18_-_47721447 0.19 ENST00000285039.7
MYO5B
myosin VB
chr12_+_51985001 0.19 ENST00000354534.6
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr16_+_2867164 0.19 ENST00000455114.1
ENST00000450020.3
PRSS21
protease, serine, 21 (testisin)
chr17_+_7591747 0.19 ENST00000534050.1
WRAP53
WD repeat containing, antisense to TP53
chr19_+_49977466 0.19 ENST00000596435.1
ENST00000344019.3
ENST00000597551.1
ENST00000204637.2
ENST00000600429.1
FLT3LG
fms-related tyrosine kinase 3 ligand
chr12_-_113574028 0.19 ENST00000546530.1
ENST00000261729.5
RASAL1
RAS protein activator like 1 (GAP1 like)
chr17_-_33469299 0.18 ENST00000586869.1
ENST00000360831.5
ENST00000442241.4
NLE1
notchless homolog 1 (Drosophila)
chr11_+_46368956 0.18 ENST00000543978.1
DGKZ
diacylglycerol kinase, zeta
chr11_+_46369077 0.18 ENST00000456247.2
ENST00000421244.2
ENST00000318201.8
DGKZ
diacylglycerol kinase, zeta
chr1_-_113249678 0.18 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC
ras homolog family member C
chr9_-_94712434 0.18 ENST00000375708.3
ROR2
receptor tyrosine kinase-like orphan receptor 2
chr17_-_19265982 0.18 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
B9D1
B9 protein domain 1
chr11_+_46368975 0.18 ENST00000527911.1
DGKZ
diacylglycerol kinase, zeta
chr22_-_30783075 0.17 ENST00000215798.6
RNF215
ring finger protein 215
chr17_+_38137050 0.17 ENST00000264639.4
PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr5_-_140998616 0.17 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1
diaphanous-related formin 1
chr10_-_6019984 0.17 ENST00000525219.2
IL15RA
interleukin 15 receptor, alpha
chr1_+_154244987 0.17 ENST00000328703.7
ENST00000457918.2
ENST00000483970.2
ENST00000435087.1
ENST00000532105.1
HAX1
HCLS1 associated protein X-1
chr1_+_145524891 0.17 ENST00000369304.3
ITGA10
integrin, alpha 10
chr1_-_6761855 0.17 ENST00000426784.1
ENST00000377573.5
ENST00000377577.5
ENST00000294401.7
DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11
chr9_-_132404374 0.17 ENST00000277459.4
ENST00000450050.2
ENST00000277458.4
ASB6
ankyrin repeat and SOCS box containing 6
chr4_-_171011084 0.17 ENST00000337664.4
AADAT
aminoadipate aminotransferase
chr17_+_1958388 0.17 ENST00000399849.3
HIC1
hypermethylated in cancer 1
chrX_+_49969405 0.17 ENST00000376042.1
CCNB3
cyclin B3
chr10_-_76995769 0.17 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr22_-_22307199 0.16 ENST00000397495.4
ENST00000263212.5
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr2_+_234263120 0.16 ENST00000264057.2
ENST00000427930.1
DGKD
diacylglycerol kinase, delta 130kDa
chr10_+_35416223 0.16 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chrX_-_27417088 0.16 ENST00000608735.1
ENST00000422048.1
RP11-268G12.1
RP11-268G12.1
chr9_+_34646651 0.16 ENST00000378842.3
GALT
galactose-1-phosphate uridylyltransferase
chr12_-_89918982 0.16 ENST00000549504.1
POC1B
POC1 centriolar protein B
chr16_-_30441293 0.16 ENST00000565758.1
ENST00000567983.1
ENST00000319285.4
DCTPP1
dCTP pyrophosphatase 1
chr16_+_2255710 0.16 ENST00000397124.1
ENST00000565250.1
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chrX_+_47053208 0.16 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
UBA1
ubiquitin-like modifier activating enzyme 1
chr3_-_190040223 0.16 ENST00000295522.3
CLDN1
claudin 1
chr10_+_17272608 0.16 ENST00000421459.2
VIM
vimentin
chr5_-_146833222 0.15 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr16_+_2867228 0.15 ENST00000005995.3
ENST00000574813.1
PRSS21
protease, serine, 21 (testisin)
chr11_-_117102768 0.15 ENST00000532301.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr5_+_148521381 0.15 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr2_+_171785824 0.15 ENST00000452526.2
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr6_-_32920794 0.15 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr6_+_35310312 0.15 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD
peroxisome proliferator-activated receptor delta
chr16_+_15737124 0.15 ENST00000396355.1
ENST00000396353.2
NDE1
nudE neurodevelopment protein 1
chr19_+_16222439 0.15 ENST00000300935.3
RAB8A
RAB8A, member RAS oncogene family
chr19_+_4791722 0.15 ENST00000269856.3
FEM1A
fem-1 homolog a (C. elegans)
chr9_+_103189660 0.15 ENST00000374886.3
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr8_+_67341239 0.15 ENST00000320270.2
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr16_+_69345243 0.15 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr16_-_69788816 0.15 ENST00000268802.5
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr11_+_61520075 0.15 ENST00000278836.5
MYRF
myelin regulatory factor
chr2_+_171785012 0.14 ENST00000234160.4
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr17_+_65375082 0.14 ENST00000584471.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr6_+_151186554 0.14 ENST00000367321.3
ENST00000367307.4
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr2_+_196440692 0.14 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr9_+_34646624 0.14 ENST00000450095.2
ENST00000556278.1
GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr16_+_55357672 0.14 ENST00000290552.7
IRX6
iroquois homeobox 6
chr9_+_129622904 0.14 ENST00000319119.4
ZBTB34
zinc finger and BTB domain containing 34
chrX_-_46618490 0.14 ENST00000328306.4
SLC9A7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr19_-_36001286 0.14 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
DMKN
dermokine
chr9_+_130965677 0.14 ENST00000393594.3
ENST00000486160.1
DNM1
dynamin 1
chr16_-_49315731 0.14 ENST00000219197.6
CBLN1
cerebellin 1 precursor
chr4_+_56814968 0.14 ENST00000422247.2
CEP135
centrosomal protein 135kDa
chr11_+_62554860 0.14 ENST00000533861.1
ENST00000333449.4
TMEM179B
transmembrane protein 179B
chr17_+_73629500 0.14 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr22_+_31160239 0.13 ENST00000445781.1
ENST00000401475.1
OSBP2
oxysterol binding protein 2
chr2_+_131113580 0.13 ENST00000175756.5
PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr1_-_113249734 0.13 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC
ras homolog family member C
chr1_+_64239657 0.13 ENST00000371080.1
ENST00000371079.1
ROR1
receptor tyrosine kinase-like orphan receptor 1
chr7_+_89783689 0.13 ENST00000297205.2
STEAP1
six transmembrane epithelial antigen of the prostate 1
chr16_+_89642120 0.13 ENST00000268720.5
ENST00000319518.8
CPNE7
copine VII
chr3_-_128369643 0.13 ENST00000296255.3
RPN1
ribophorin I
chr13_-_88323514 0.13 ENST00000441617.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr11_-_117103208 0.13 ENST00000320934.3
ENST00000530269.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr15_+_75074385 0.13 ENST00000220003.9
CSK
c-src tyrosine kinase
chr5_-_140998481 0.13 ENST00000518047.1
DIAPH1
diaphanous-related formin 1
chr5_+_148521046 0.13 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
ABLIM3
actin binding LIM protein family, member 3
chr15_-_71407806 0.13 ENST00000566432.1
ENST00000567117.1
CT62
cancer/testis antigen 62
chr14_+_101293687 0.13 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chrX_-_102942961 0.13 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
MORF4L2
mortality factor 4 like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of RAD21_SMC3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291) negative regulation of CD40 signaling pathway(GO:2000349)
0.4 1.3 GO:2000627 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.3 0.9 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.3 0.9 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 0.8 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.2 0.5 GO:0032203 telomere formation via telomerase(GO:0032203)
0.2 0.6 GO:0019230 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283) proprioception(GO:0019230)
0.1 0.4 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.1 0.5 GO:0044691 tooth eruption(GO:0044691)
0.1 1.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.3 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.7 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.4 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.1 0.6 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.1 0.3 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.3 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.5 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.3 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.3 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.7 GO:0003383 apical constriction(GO:0003383)
0.1 0.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.2 GO:0090289 regulation of osteoclast proliferation(GO:0090289)
0.1 0.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 3.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.4 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.4 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.2 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.3 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.8 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.0 0.1 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.2 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.6 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.2 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.1 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.2 GO:1902231 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.0 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.1 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738) negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:0010988 regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) protein localization to nucleolus(GO:1902570)
0.0 0.0 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0035106 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051) operant conditioning(GO:0035106)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:0044843 cell cycle G1/S phase transition(GO:0044843)
0.0 0.1 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.0 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 1.3 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.5 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:1903027 asymmetric Golgi ribbon formation(GO:0090164) regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 0.0 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.0 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.0 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 GO:0016234 inclusion body(GO:0016234)
0.2 0.8 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 1.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 0.5 GO:0005584 collagen type I trimer(GO:0005584)
0.1 0.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.5 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.3 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.5 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 3.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 1.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0005874 microtubule(GO:0005874)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 0.8 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.2 3.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.7 GO:0031014 troponin T binding(GO:0031014)
0.1 0.5 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.2 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.0 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.0 GO:0030984 kininogen binding(GO:0030984)
0.0 0.1 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.3 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 4.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.0 GO:0008240 tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.0 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0036041 long-chain fatty acid binding(GO:0036041)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 4.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.7 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation