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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for REL

Z-value: 2.09

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Transcription factors associated with REL

Gene Symbol Gene ID Gene Info
REL
ENSG00000162924.9 REL proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELhg19_v2_chr2_+_61108771_61108791-0.562.5e-01Click!

Activity profile of REL motif

Sorted Z-values of REL motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_138188351 5.39 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_+_138188551 5.25 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_+_138188378 4.91 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr4_-_74864386 3.91 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr2_+_228678550 3.83 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr5_-_150467221 2.80 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr4_+_74735102 2.61 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr11_+_102188272 2.59 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr14_+_103589789 2.48 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr5_-_150460914 2.41 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr11_+_102188224 2.27 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr4_-_74904398 2.08 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr5_-_150466692 2.00 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr4_+_74702214 1.99 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr10_+_104155450 1.83 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr20_+_43803517 1.82 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chrX_+_115567767 1.69 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr6_-_31550192 1.53 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr10_+_30723045 1.32 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr2_-_113594279 1.27 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr10_+_104154229 1.21 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr10_+_30722866 1.21 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr8_-_23712312 1.20 ENST00000290271.2
STC1
stanniocalcin 1
chr10_+_30723105 1.17 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr14_+_103243813 1.14 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3
chr14_+_75988851 1.07 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr17_-_76356148 1.06 ENST00000587578.1
ENST00000330871.2
SOCS3
suppressor of cytokine signaling 3
chr14_-_35873856 1.02 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr6_+_32821924 1.01 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr3_+_101546827 0.92 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr20_-_43753104 0.87 ENST00000372785.3
WFDC12
WAP four-disulfide core domain 12
chr17_+_40440481 0.87 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr12_+_51632666 0.81 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr6_-_44233361 0.78 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr12_+_102271129 0.77 ENST00000258534.8
DRAM1
DNA-damage regulated autophagy modulator 1
chr1_-_89738528 0.69 ENST00000343435.5
GBP5
guanylate binding protein 5
chr8_+_72755367 0.68 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr9_-_117880477 0.66 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
TNC
tenascin C
chr17_-_4642429 0.65 ENST00000573123.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr5_-_115890554 0.64 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr19_-_46272106 0.64 ENST00000560168.1
SIX5
SIX homeobox 5
chr9_+_130911723 0.62 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr19_+_13988061 0.58 ENST00000339133.5
ENST00000397555.2
NANOS3
nanos homolog 3 (Drosophila)
chr2_-_191885686 0.58 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr17_+_40440094 0.58 ENST00000546010.2
STAT5A
signal transducer and activator of transcription 5A
chr11_-_128392085 0.56 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr16_+_50730910 0.56 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chrX_+_48755183 0.56 ENST00000376563.1
ENST00000376566.4
PQBP1
polyglutamine binding protein 1
chr5_+_118604385 0.55 ENST00000274456.6
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr5_+_118604439 0.55 ENST00000388882.5
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr17_-_56591321 0.54 ENST00000583243.1
MTMR4
myotubularin related protein 4
chr1_+_144339738 0.53 ENST00000538264.1
AL592284.1
Protein LOC642441
chr1_-_205912577 0.52 ENST00000367135.3
ENST00000367134.2
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr9_+_130911770 0.52 ENST00000372998.1
LCN2
lipocalin 2
chr19_+_4229495 0.52 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr6_-_29527702 0.51 ENST00000377050.4
UBD
ubiquitin D
chr1_+_165796753 0.51 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr12_+_102271436 0.51 ENST00000544152.1
DRAM1
DNA-damage regulated autophagy modulator 1
chr12_-_49318715 0.50 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr9_-_136344197 0.49 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr14_-_69446034 0.48 ENST00000193403.6
ACTN1
actinin, alpha 1
chr11_+_73000449 0.48 ENST00000535931.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr6_+_292253 0.48 ENST00000603453.1
ENST00000605315.1
ENST00000603881.1
DUSP22
dual specificity phosphatase 22
chr9_+_130547958 0.48 ENST00000421939.1
ENST00000373265.2
CDK9
cyclin-dependent kinase 9
chr2_-_163175133 0.47 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr20_-_43977055 0.47 ENST00000372733.3
ENST00000537976.1
SDC4
syndecan 4
chr12_-_7281469 0.47 ENST00000542370.1
ENST00000266560.3
RBP5
retinol binding protein 5, cellular
chr22_+_46731596 0.47 ENST00000381019.3
TRMU
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr2_+_162165038 0.45 ENST00000437630.1
PSMD14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr20_+_44746939 0.44 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr11_-_58345569 0.43 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr8_-_123793048 0.43 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr20_+_44746885 0.42 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr5_-_141703713 0.42 ENST00000511815.1
SPRY4
sprouty homolog 4 (Drosophila)
chr12_-_62997214 0.41 ENST00000408887.2
C12orf61
chromosome 12 open reading frame 61
chr2_+_220094479 0.40 ENST00000323348.5
ENST00000453432.1
ENST00000409849.1
ENST00000416565.1
ENST00000410034.3
ENST00000447157.1
ANKZF1
ankyrin repeat and zinc finger domain containing 1
chr19_-_4338838 0.40 ENST00000594605.1
STAP2
signal transducing adaptor family member 2
chr6_-_32122106 0.39 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr17_-_4643114 0.39 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chr10_-_18948208 0.39 ENST00000607346.1
ARL5B-AS1
ARL5B antisense RNA 1
chr10_+_99609996 0.39 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr1_-_8086343 0.38 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERRFI1
ERBB receptor feedback inhibitor 1
chr21_-_34915084 0.37 ENST00000426819.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr5_-_149792295 0.37 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr17_-_4852332 0.35 ENST00000572383.1
PFN1
profilin 1
chr11_+_10476851 0.35 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr1_+_16767195 0.35 ENST00000504551.2
ENST00000457722.2
ENST00000406746.1
ENST00000443980.2
NECAP2
NECAP endocytosis associated 2
chr19_-_4338783 0.35 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr12_+_51632600 0.33 ENST00000549555.1
ENST00000439799.2
ENST00000425012.2
DAZAP2
DAZ associated protein 2
chr3_+_169629354 0.33 ENST00000428432.2
ENST00000335556.3
SAMD7
sterile alpha motif domain containing 7
chr15_+_67430339 0.33 ENST00000439724.3
SMAD3
SMAD family member 3
chr17_+_80477571 0.33 ENST00000335255.5
FOXK2
forkhead box K2
chr3_-_156878482 0.32 ENST00000295925.4
CCNL1
cyclin L1
chr1_+_6845384 0.32 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr7_-_99679324 0.31 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
ZNF3
zinc finger protein 3
chr5_+_14143728 0.31 ENST00000344204.4
ENST00000537187.1
TRIO
trio Rho guanine nucleotide exchange factor
chr19_+_41256764 0.30 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr16_-_88717423 0.30 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA
cytochrome b-245, alpha polypeptide
chr18_+_21529811 0.30 ENST00000588004.1
LAMA3
laminin, alpha 3
chr17_+_26662730 0.30 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr6_+_135502408 0.30 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr6_+_15401075 0.29 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr10_-_91295304 0.29 ENST00000341233.4
ENST00000371790.4
SLC16A12
solute carrier family 16, member 12
chr1_+_110453203 0.28 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr12_-_49504655 0.28 ENST00000551782.1
ENST00000267102.8
LMBR1L
limb development membrane protein 1-like
chr8_-_105601134 0.28 ENST00000276654.5
ENST00000424843.2
LRP12
low density lipoprotein receptor-related protein 12
chr5_-_138842286 0.28 ENST00000515823.1
ECSCR
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr6_-_32821599 0.27 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr14_-_24616426 0.27 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr12_-_76425368 0.27 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr21_+_34775698 0.26 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr1_-_155959853 0.26 ENST00000462460.2
ENST00000368316.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr3_-_179322416 0.26 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr2_+_173940668 0.26 ENST00000375213.3
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr19_-_47734448 0.26 ENST00000439096.2
BBC3
BCL2 binding component 3
chr2_-_27357479 0.25 ENST00000406567.3
ENST00000260643.2
PREB
prolactin regulatory element binding
chr15_+_57891609 0.25 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr1_-_235813290 0.25 ENST00000391854.2
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr1_-_113249948 0.25 ENST00000339083.7
ENST00000369642.3
RHOC
ras homolog family member C
chr2_+_102314161 0.24 ENST00000425019.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_+_220094657 0.24 ENST00000436226.1
ANKZF1
ankyrin repeat and zinc finger domain containing 1
chr14_+_68086515 0.24 ENST00000261783.3
ARG2
arginase 2
chr4_-_76957214 0.24 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr17_-_15469590 0.24 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr21_+_34775772 0.23 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr5_+_133984462 0.23 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr17_-_4643161 0.23 ENST00000574412.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr7_+_143771275 0.23 ENST00000408898.2
OR2A25
olfactory receptor, family 2, subfamily A, member 25
chr18_-_56985776 0.23 ENST00000587244.1
CPLX4
complexin 4
chr3_+_197518100 0.22 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr14_-_24658053 0.22 ENST00000354464.6
IPO4
importin 4
chr1_-_209824643 0.22 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr1_-_6453426 0.22 ENST00000545482.1
ACOT7
acyl-CoA thioesterase 7
chr12_+_50690489 0.22 ENST00000598429.1
AC140061.12
Uncharacterized protein
chr7_+_18548924 0.22 ENST00000524023.1
HDAC9
histone deacetylase 9
chr8_-_119964434 0.21 ENST00000297350.4
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr2_-_18741882 0.21 ENST00000381249.3
RDH14
retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
chr6_-_131291572 0.21 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr19_-_39390212 0.21 ENST00000437828.1
SIRT2
sirtuin 2
chr21_-_34915147 0.21 ENST00000381831.3
ENST00000381839.3
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr12_+_51633061 0.20 ENST00000551313.1
DAZAP2
DAZ associated protein 2
chr1_+_110453462 0.20 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr8_+_144816303 0.20 ENST00000533004.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr1_-_204436344 0.20 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr6_+_12008986 0.20 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr3_+_101280677 0.19 ENST00000309922.6
ENST00000495642.1
TRMT10C
tRNA methyltransferase 10 homolog C (S. cerevisiae)
chr7_+_18548878 0.19 ENST00000456174.2
HDAC9
histone deacetylase 9
chr3_+_47844615 0.19 ENST00000348968.4
DHX30
DEAH (Asp-Glu-Ala-His) box helicase 30
chr1_-_226595648 0.18 ENST00000366790.3
PARP1
poly (ADP-ribose) polymerase 1
chr2_+_114647504 0.18 ENST00000263238.2
ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr16_+_27325202 0.18 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
IL4R
interleukin 4 receptor
chr5_+_154136702 0.18 ENST00000524248.1
LARP1
La ribonucleoprotein domain family, member 1
chr19_-_51471381 0.18 ENST00000594641.1
KLK6
kallikrein-related peptidase 6
chr19_-_4831701 0.18 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr4_-_185395191 0.18 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr16_+_27324983 0.18 ENST00000566117.1
IL4R
interleukin 4 receptor
chr3_-_196230590 0.17 ENST00000318037.3
RNF168
ring finger protein 168, E3 ubiquitin protein ligase
chr3_+_183967409 0.17 ENST00000324557.4
ENST00000402825.3
ECE2
endothelin converting enzyme 2
chr1_-_159894319 0.17 ENST00000320307.4
TAGLN2
transgelin 2
chr1_-_65432171 0.17 ENST00000342505.4
JAK1
Janus kinase 1
chr10_+_89124746 0.16 ENST00000465545.1
NUTM2D
NUT family member 2D
chr13_-_88323218 0.16 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr21_+_34775181 0.16 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr19_+_3721719 0.15 ENST00000589378.1
ENST00000382008.3
TJP3
tight junction protein 3
chr7_-_98741642 0.15 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr11_-_72492903 0.15 ENST00000537947.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr16_+_3096638 0.15 ENST00000336577.4
MMP25
matrix metallopeptidase 25
chr15_-_42302445 0.15 ENST00000413860.2
PLA2G4E
phospholipase A2, group IVE
chr2_+_201987200 0.14 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr3_-_179322436 0.14 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr18_+_3252265 0.14 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr19_+_496454 0.14 ENST00000346144.4
ENST00000215637.3
ENST00000382683.4
MADCAM1
mucosal vascular addressin cell adhesion molecule 1
chr3_-_139108475 0.14 ENST00000515006.1
ENST00000513274.1
ENST00000514508.1
ENST00000507777.1
ENST00000512153.1
ENST00000333188.5
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr2_+_16080659 0.14 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr9_+_101705893 0.14 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr16_+_67571351 0.14 ENST00000428437.2
ENST00000569253.1
FAM65A
family with sequence similarity 65, member A
chr6_-_166075557 0.13 ENST00000539869.2
ENST00000366882.1
PDE10A
phosphodiesterase 10A
chr9_-_132805430 0.13 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1
formin binding protein 1
chr6_-_31774714 0.13 ENST00000375661.5
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_+_4643337 0.13 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr4_-_103749179 0.12 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr11_-_61734599 0.12 ENST00000532601.1
FTH1
ferritin, heavy polypeptide 1
chr19_-_46145696 0.12 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr16_+_84209539 0.12 ENST00000569735.1
DNAAF1
dynein, axonemal, assembly factor 1
chr12_-_56211485 0.12 ENST00000552080.1
ENST00000444631.2
ENST00000336133.3
SARNP
SAP domain containing ribonucleoprotein
chr18_+_21452804 0.12 ENST00000269217.6
LAMA3
laminin, alpha 3
chr17_-_1420182 0.12 ENST00000421807.2
INPP5K
inositol polyphosphate-5-phosphatase K
chr9_+_132934835 0.11 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr20_-_33872518 0.11 ENST00000374436.3
EIF6
eukaryotic translation initiation factor 6
chr1_-_9189144 0.11 ENST00000414642.2
GPR157
G protein-coupled receptor 157
chr2_-_204400113 0.11 ENST00000319170.5
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr19_+_11466062 0.10 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr16_+_3014217 0.10 ENST00000572045.1
KREMEN2
kringle containing transmembrane protein 2
chr8_+_55467072 0.10 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr6_+_30850862 0.10 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr16_+_84209738 0.10 ENST00000564928.1
DNAAF1
dynein, axonemal, assembly factor 1
chr10_+_13142075 0.10 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr6_-_131384347 0.10 ENST00000530481.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr16_-_15736953 0.10 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
KIAA0430
KIAA0430
chr12_-_96793142 0.10 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.5 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291) negative regulation of CD40 signaling pathway(GO:2000349)
1.4 7.2 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.3 3.8 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.8 3.0 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.4 10.9 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.4 4.9 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.3 1.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.3 1.4 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 0.6 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.3 1.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 0.7 GO:0072616 interleukin-18 secretion(GO:0072616)
0.2 1.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2 0.7 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.2 1.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.3 GO:0031620 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.2 0.9 GO:0033590 response to cobalamin(GO:0033590)
0.2 1.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 2.5 GO:0051601 exocyst localization(GO:0051601)
0.1 0.6 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.5 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.5 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.5 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 1.8 GO:0007620 copulation(GO:0007620)
0.1 0.3 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.7 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.5 GO:1904141 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.1 0.5 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 1.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 1.5 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 0.8 GO:0042940 D-amino acid transport(GO:0042940)
0.1 0.6 GO:1904996 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.3 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 0.2 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.2 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.1 0.7 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 0.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.2 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.5 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.5 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.9 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.5 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.6 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.6 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.5 GO:0035589 transepithelial chloride transport(GO:0030321) G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.5 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.8 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 2.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 2.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 1.8 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.1 GO:0033864 regulation of NAD(P)H oxidase activity(GO:0033860) positive regulation of NAD(P)H oxidase activity(GO:0033864)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.0 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.5 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:1903943 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0060022 hard palate development(GO:0060022)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.7 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 0.9 GO:0043196 varicosity(GO:0043196)
0.1 1.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.6 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 2.5 GO:0000145 exocyst(GO:0000145)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.7 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.6 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 3.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 16.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.8 16.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.8 10.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.6 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.1 0.4 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.1 7.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.7 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 4.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.1 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.5 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.7 GO:0045545 syndecan binding(GO:0045545)
0.1 1.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 1.3 GO:0008009 chemokine activity(GO:0008009)
0.1 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 1.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 2.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.6 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 1.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.5 GO:0016918 retinal binding(GO:0016918)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.0 0.0 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 2.6 GO:0000149 SNARE binding(GO:0000149)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 24.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 3.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 7.0 PID IL23 PATHWAY IL23-mediated signaling events
0.1 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 2.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 13.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.9 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 15.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 20.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 3.4 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 5.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 2.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions