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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RELB

Z-value: 1.42

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Transcription factors associated with RELB

Gene Symbol Gene ID Gene Info
RELB
ENSG00000104856.9 RELB proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELBhg19_v2_chr19_+_45504688_455047820.954.0e-03Click!

Activity profile of RELB motif

Sorted Z-values of RELB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_74864386 3.14 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr7_+_22766766 2.77 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr2_+_113735575 2.70 ENST00000376489.2
ENST00000259205.4
IL36G
interleukin 36, gamma
chr11_+_18287801 2.29 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr11_+_18287721 2.28 ENST00000356524.4
SAA1
serum amyloid A1
chr4_-_74904398 2.21 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr1_-_153113927 2.07 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr1_+_37940153 1.99 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr6_+_138188351 1.98 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_+_138188551 1.85 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr14_+_103589789 1.77 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr6_+_138188378 1.57 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr22_-_30642728 1.44 ENST00000403987.3
LIF
leukemia inhibitory factor
chr5_-_150460914 1.30 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr12_-_49259643 1.26 ENST00000309739.5
RND1
Rho family GTPase 1
chr5_-_150460539 1.20 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr11_+_102188272 1.20 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr4_+_74702214 1.19 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr10_+_12391685 1.13 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr4_-_74964904 1.10 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr11_+_102188224 1.04 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr5_-_150467221 1.04 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr4_+_74735102 0.98 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr14_+_103243813 0.98 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3
chr21_-_44898015 0.97 ENST00000332440.3
LINC00313
long intergenic non-protein coding RNA 313
chr10_+_104154229 0.96 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr6_+_32821924 0.93 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr2_-_36779411 0.85 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr17_+_40440481 0.82 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr14_-_35873856 0.81 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr19_+_45504688 0.79 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr17_+_48351785 0.64 ENST00000507382.1
TMEM92
transmembrane protein 92
chr8_+_72755367 0.59 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr6_-_29527702 0.58 ENST00000377050.4
UBD
ubiquitin D
chr4_+_103423055 0.57 ENST00000505458.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr2_-_191885686 0.55 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr10_+_30722866 0.54 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr7_+_76054224 0.52 ENST00000394857.3
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr14_+_75988851 0.52 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr6_+_126221034 0.50 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr6_-_36355513 0.46 ENST00000340181.4
ENST00000373737.4
ETV7
ets variant 7
chr16_-_2059748 0.46 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr14_-_69446034 0.45 ENST00000193403.6
ACTN1
actinin, alpha 1
chr20_+_44035200 0.45 ENST00000372717.1
ENST00000360981.4
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr2_-_27718052 0.45 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr16_-_30134266 0.45 ENST00000484663.1
ENST00000478356.1
MAPK3
mitogen-activated protein kinase 3
chr3_-_186262166 0.45 ENST00000307944.5
CRYGS
crystallin, gamma S
chr17_-_27053216 0.44 ENST00000292090.3
TLCD1
TLC domain containing 1
chr14_+_64971438 0.44 ENST00000555321.1
ZBTB1
zinc finger and BTB domain containing 1
chr12_-_92539614 0.44 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr9_-_136344197 0.44 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr6_+_292253 0.43 ENST00000603453.1
ENST00000605315.1
ENST00000603881.1
DUSP22
dual specificity phosphatase 22
chr16_-_30134441 0.43 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr2_+_89952792 0.42 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr12_+_96588143 0.40 ENST00000228741.3
ENST00000547249.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr12_-_122018114 0.40 ENST00000539394.1
KDM2B
lysine (K)-specific demethylase 2B
chr1_+_156611900 0.40 ENST00000457777.2
ENST00000424639.1
BCAN
brevican
chr11_+_64052692 0.40 ENST00000377702.4
GPR137
G protein-coupled receptor 137
chr22_+_31644309 0.37 ENST00000425203.1
LIMK2
LIM domain kinase 2
chr2_-_163175133 0.37 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr11_+_10477733 0.37 ENST00000528723.1
AMPD3
adenosine monophosphate deaminase 3
chr17_+_45908974 0.37 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr16_+_50730910 0.36 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr19_-_4540486 0.36 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr5_-_149792295 0.36 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr5_+_140579162 0.36 ENST00000536699.1
ENST00000354757.3
PCDHB11
protocadherin beta 11
chr1_-_186649543 0.36 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr11_+_73000449 0.36 ENST00000535931.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr16_-_30134524 0.35 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3
mitogen-activated protein kinase 3
chr20_+_44035847 0.35 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr6_+_15401075 0.35 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr5_-_150521192 0.35 ENST00000523714.1
ENST00000521749.1
ANXA6
annexin A6
chr1_-_6321035 0.34 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr8_-_65711310 0.33 ENST00000310193.3
CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
chr15_+_57891609 0.32 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr6_-_36355486 0.32 ENST00000538992.1
ETV7
ets variant 7
chr1_+_35225339 0.32 ENST00000339480.1
GJB4
gap junction protein, beta 4, 30.3kDa
chr9_+_130547958 0.31 ENST00000421939.1
ENST00000373265.2
CDK9
cyclin-dependent kinase 9
chr16_+_2059872 0.31 ENST00000567649.1
NPW
neuropeptide W
chr9_+_33240157 0.31 ENST00000379721.3
SPINK4
serine peptidase inhibitor, Kazal type 4
chrX_+_108780347 0.31 ENST00000372103.1
NXT2
nuclear transport factor 2-like export factor 2
chr5_-_146833222 0.30 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr3_+_52454971 0.30 ENST00000465863.1
PHF7
PHD finger protein 7
chr1_+_110453203 0.29 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr6_+_116782527 0.29 ENST00000368606.3
ENST00000368605.1
FAM26F
family with sequence similarity 26, member F
chr12_+_96588368 0.28 ENST00000547860.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr14_-_64970494 0.28 ENST00000608382.1
ZBTB25
zinc finger and BTB domain containing 25
chr3_-_156878482 0.27 ENST00000295925.4
CCNL1
cyclin L1
chr11_-_58345569 0.27 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr12_+_57623907 0.27 ENST00000553529.1
ENST00000554310.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr14_+_71788096 0.27 ENST00000557151.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr19_+_18492973 0.27 ENST00000595973.2
GDF15
growth differentiation factor 15
chr1_-_183559693 0.27 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr2_+_242498135 0.26 ENST00000318407.3
BOK
BCL2-related ovarian killer
chr9_-_130517522 0.26 ENST00000373274.3
ENST00000420366.1
SH2D3C
SH2 domain containing 3C
chr12_-_49318715 0.26 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr1_-_173886491 0.26 ENST00000367698.3
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr6_+_33378517 0.25 ENST00000428274.1
PHF1
PHD finger protein 1
chr6_-_32821599 0.25 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr2_+_201987200 0.25 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr3_+_171844762 0.25 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr11_+_64052454 0.23 ENST00000539833.1
GPR137
G protein-coupled receptor 137
chr11_+_123396307 0.23 ENST00000456860.2
GRAMD1B
GRAM domain containing 1B
chr14_+_23299088 0.23 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr14_-_64971893 0.23 ENST00000555220.1
ZBTB25
zinc finger and BTB domain containing 25
chr19_-_4831701 0.23 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr21_+_34775698 0.22 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr12_+_57624059 0.22 ENST00000557427.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr12_-_125473600 0.22 ENST00000308736.2
DHX37
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr1_+_95975672 0.21 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr2_+_234826016 0.21 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr7_-_111202511 0.21 ENST00000452895.1
ENST00000452753.1
ENST00000331762.3
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr9_-_139334247 0.21 ENST00000371712.3
INPP5E
inositol polyphosphate-5-phosphatase, 72 kDa
chr12_-_108991778 0.21 ENST00000549447.1
TMEM119
transmembrane protein 119
chr1_+_202830876 0.21 ENST00000456105.2
RP11-480I12.7
RP11-480I12.7
chr11_+_64052266 0.21 ENST00000539851.1
GPR137
G protein-coupled receptor 137
chr14_-_69262916 0.21 ENST00000553375.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr3_+_184032419 0.19 ENST00000352767.3
ENST00000427141.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr20_-_2451395 0.19 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
chr7_+_18548878 0.19 ENST00000456174.2
HDAC9
histone deacetylase 9
chr16_+_3096638 0.18 ENST00000336577.4
MMP25
matrix metallopeptidase 25
chr12_+_57623869 0.18 ENST00000414700.3
ENST00000557703.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr16_+_53738053 0.18 ENST00000394647.3
FTO
fat mass and obesity associated
chr19_-_10679697 0.18 ENST00000335766.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr16_-_2059797 0.18 ENST00000563630.1
ZNF598
zinc finger protein 598
chr10_+_114710425 0.18 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr18_+_21529811 0.18 ENST00000588004.1
LAMA3
laminin, alpha 3
chr17_+_37793318 0.17 ENST00000336308.5
STARD3
StAR-related lipid transfer (START) domain containing 3
chr18_+_2846972 0.17 ENST00000254528.3
EMILIN2
elastin microfibril interfacer 2
chr15_-_72668185 0.17 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA
hexosaminidase A (alpha polypeptide)
chr21_+_45287112 0.17 ENST00000448287.1
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr2_+_64681103 0.17 ENST00000464281.1
LGALSL
lectin, galactoside-binding-like
chr14_+_96858454 0.17 ENST00000555570.1
AK7
adenylate kinase 7
chr15_+_45544426 0.17 ENST00000347644.3
ENST00000560438.1
SLC28A2
solute carrier family 28 (concentrative nucleoside transporter), member 2
chr5_-_43313269 0.16 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr21_+_34775772 0.16 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr1_-_204436344 0.16 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr3_-_5229982 0.16 ENST00000600805.1
AC026202.1
Uncharacterized protein
chr3_-_151176497 0.16 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr4_-_185395191 0.16 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr17_-_39942322 0.16 ENST00000449889.1
ENST00000465293.1
JUP
junction plakoglobin
chr20_-_44600810 0.16 ENST00000322927.2
ENST00000426788.1
ZNF335
zinc finger protein 335
chr4_-_170897045 0.16 ENST00000508313.1
RP11-205M3.3
RP11-205M3.3
chr7_+_18548924 0.16 ENST00000524023.1
HDAC9
histone deacetylase 9
chr2_-_27592867 0.16 ENST00000451130.2
EIF2B4
eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
chr11_+_126262027 0.16 ENST00000526311.1
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr3_+_184032283 0.16 ENST00000346169.2
ENST00000414031.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr12_+_7053172 0.16 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr1_+_156119466 0.15 ENST00000414683.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr2_+_68870721 0.15 ENST00000303786.3
PROKR1
prokineticin receptor 1
chr1_-_113249678 0.15 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC
ras homolog family member C
chr9_-_32526184 0.15 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr3_+_184032313 0.15 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr7_-_22539771 0.15 ENST00000406890.2
ENST00000424363.1
STEAP1B
STEAP family member 1B
chr12_+_57623477 0.15 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr2_-_61108449 0.15 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr16_-_4850471 0.15 ENST00000592019.1
ENST00000586153.1
ROGDI
rogdi homolog (Drosophila)
chr8_+_22022800 0.15 ENST00000397814.3
BMP1
bone morphogenetic protein 1
chr12_+_57624119 0.15 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr21_-_33984456 0.14 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
AP000275.65
C21orf59
Uncharacterized protein
chromosome 21 open reading frame 59
chr1_-_155211017 0.14 ENST00000536770.1
ENST00000368373.3
GBA
glucosidase, beta, acid
chr10_+_77056181 0.14 ENST00000526759.1
ENST00000533822.1
ZNF503-AS1
ZNF503 antisense RNA 1
chr6_+_42018614 0.14 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr16_+_73420942 0.14 ENST00000554640.1
ENST00000562661.1
ENST00000561875.1
RP11-140I24.1
RP11-140I24.1
chrX_-_24665208 0.14 ENST00000356768.4
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr9_-_32526299 0.14 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr7_+_86273218 0.14 ENST00000361669.2
GRM3
glutamate receptor, metabotropic 3
chr8_-_128231299 0.14 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr3_+_160822462 0.14 ENST00000468606.1
ENST00000460503.1
NMD3
NMD3 ribosome export adaptor
chr15_-_40600026 0.14 ENST00000456256.2
ENST00000557821.1
PLCB2
phospholipase C, beta 2
chr17_-_77005801 0.14 ENST00000392446.5
CANT1
calcium activated nucleotidase 1
chr4_-_21950356 0.14 ENST00000447367.2
ENST00000382152.2
KCNIP4
Kv channel interacting protein 4
chr15_-_101817616 0.13 ENST00000526049.1
ENST00000398226.3
ENST00000537379.1
VIMP
VCP-interacting membrane protein
chr8_+_55467072 0.13 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr6_-_10838736 0.13 ENST00000536370.1
ENST00000474039.1
MAK
male germ cell-associated kinase
chr10_+_114710211 0.13 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr1_-_156710916 0.13 ENST00000368211.4
MRPL24
mitochondrial ribosomal protein L24
chr19_-_46145696 0.13 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr12_+_57624085 0.12 ENST00000553474.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr14_-_24701539 0.12 ENST00000534348.1
ENST00000524927.1
ENST00000250495.5
NEDD8-MDP1
NEDD8
NEDD8-MDP1 readthrough
neural precursor cell expressed, developmentally down-regulated 8
chr4_-_114900126 0.12 ENST00000541197.1
ARSJ
arylsulfatase family, member J
chr17_-_77005860 0.12 ENST00000591773.1
ENST00000588611.1
ENST00000586916.2
ENST00000592033.1
ENST00000588075.1
ENST00000302345.2
ENST00000591811.1
CANT1
calcium activated nucleotidase 1
chr1_+_110453462 0.12 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr4_+_39046615 0.12 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr17_-_39968406 0.12 ENST00000393928.1
LEPREL4
leprecan-like 4
chr1_-_94079648 0.12 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr20_+_44098346 0.12 ENST00000372676.3
WFDC2
WAP four-disulfide core domain 2
chr20_+_34680698 0.12 ENST00000447825.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr1_+_8021954 0.12 ENST00000377491.1
ENST00000377488.1
PARK7
parkinson protein 7
chr1_+_180165672 0.12 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chrX_-_134186144 0.12 ENST00000370775.2
FAM127B
family with sequence similarity 127, member B
chr1_-_155959853 0.11 ENST00000462460.2
ENST00000368316.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr11_-_64052111 0.11 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BAD
BCL2-associated agonist of cell death
chrX_-_72347916 0.11 ENST00000373518.1
NAP1L6
nucleosome assembly protein 1-like 6
chrX_+_107683096 0.11 ENST00000328300.6
ENST00000361603.2
COL4A5
collagen, type IV, alpha 5
chr3_+_63805017 0.11 ENST00000295896.8
C3orf49
chromosome 3 open reading frame 49
chr22_+_37678505 0.11 ENST00000402997.1
ENST00000405206.3
CYTH4
cytohesin 4
chr12_-_24737089 0.11 ENST00000483544.1
LINC00477
long intergenic non-protein coding RNA 477
chr1_+_46713357 0.11 ENST00000442598.1
RAD54L
RAD54-like (S. cerevisiae)
chr16_+_88636789 0.11 ENST00000301011.5
ENST00000452588.2
ZC3H18
zinc finger CCCH-type containing 18

Network of associatons between targets according to the STRING database.

First level regulatory network of RELB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0090291 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291) negative regulation of CD40 signaling pathway(GO:2000349)
0.7 3.5 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.7 2.8 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.7 2.0 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.4 1.2 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.4 9.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.3 1.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.3 0.8 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.2 1.0 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.2 0.6 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.2 2.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2 0.4 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.2 0.7 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 0.8 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 0.6 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 1.0 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.6 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.5 GO:0060467 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) negative regulation of fertilization(GO:0060467) acrosomal vesicle exocytosis(GO:0060478) regulation of ovarian follicle development(GO:2000354) regulation of binding of sperm to zona pellucida(GO:2000359) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 4.6 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 0.4 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 1.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 1.8 GO:0051601 exocyst localization(GO:0051601)
0.1 0.5 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.1 0.5 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.3 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 1.3 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.2 GO:1903384 enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.2 GO:0042245 RNA repair(GO:0042245)
0.1 0.6 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.3 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.3 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.1 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957) positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.1 GO:0052151 negative regulation of cytolysis(GO:0045918) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.2 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.1 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.3 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 2.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.9 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.3 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.2 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.2 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309) negative regulation of T-helper 17 cell lineage commitment(GO:2000329) regulation of dendritic cell chemotaxis(GO:2000508)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.5 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0090325 regulation of locomotion involved in locomotory behavior(GO:0090325)
0.0 0.2 GO:0060022 hard palate development(GO:0060022)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.4 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.3 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.2 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 2.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 1.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 1.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 4.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.5 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 0.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.1 GO:0070552 BRISC complex(GO:0070552)
0.1 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.8 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0 2.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.5 GO:0097342 ripoptosome(GO:0097342)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 1.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.5 1.4 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.3 5.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 2.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 2.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.1 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 4.6 GO:0042056 chemoattractant activity(GO:0042056)
0.1 2.0 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.5 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.4 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 1.0 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.5 GO:0032190 acrosin binding(GO:0032190)
0.1 3.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.2 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.2 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.1 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.0 1.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.4 GO:0032452 histone demethylase activity(GO:0032452)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 ST STAT3 PATHWAY STAT3 Pathway
0.2 10.4 PID CD40 PATHWAY CD40/CD40L signaling
0.1 4.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 0.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 12.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2 5.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 3.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 8.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 8.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation