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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for RFX5
Z-value: 0.35
Motif logo
Transcription factors associated with RFX5
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RFX5
|
ENSG00000143390.13 | regulatory factor X5 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RFX5 | hg19_v2_chr1_-_151319283_151319314 | 0.63 | 1.8e-01 | Click! |
Activity profile of RFX5 motif
Sorted Z-values of RFX5 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_+_33043703 | 0.30 |
ENST00000418931.2
ENST00000535465.1 |
HLA-DPB1
|
major histocompatibility complex, class II, DP beta 1 |
| chr19_+_50031547 | 0.19 |
ENST00000597801.1
|
RCN3
|
reticulocalbin 3, EF-hand calcium binding domain |
| chr19_-_49118067 | 0.14 |
ENST00000593772.1
|
FAM83E
|
family with sequence similarity 83, member E |
| chr6_+_32821924 | 0.13 |
ENST00000374859.2
ENST00000453265.2 |
PSMB9
|
proteasome (prosome, macropain) subunit, beta type, 9 |
| chr6_-_32812420 | 0.13 |
ENST00000374881.2
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8 |
| chr16_-_74808710 | 0.12 |
ENST00000219368.3
ENST00000544337.1 |
FA2H
|
fatty acid 2-hydroxylase |
| chrX_+_125953746 | 0.12 |
ENST00000371125.3
|
CXorf64
|
chromosome X open reading frame 64 |
| chr17_-_19265855 | 0.12 |
ENST00000440841.1
ENST00000395615.1 ENST00000461069.2 |
B9D1
|
B9 protein domain 1 |
| chr17_+_27052892 | 0.11 |
ENST00000579671.1
ENST00000579060.1 |
NEK8
|
NIMA-related kinase 8 |
| chr19_-_6057282 | 0.11 |
ENST00000592281.1
|
RFX2
|
regulatory factor X, 2 (influences HLA class II expression) |
| chr10_-_82116505 | 0.11 |
ENST00000372202.1
ENST00000421924.2 ENST00000453477.1 |
DYDC1
|
DPY30 domain containing 1 |
| chr6_+_26383404 | 0.10 |
ENST00000416795.2
ENST00000494184.1 |
BTN2A2
|
butyrophilin, subfamily 2, member A2 |
| chr3_+_9850199 | 0.09 |
ENST00000452597.1
|
TTLL3
|
tubulin tyrosine ligase-like family, member 3 |
| chr19_+_19496728 | 0.09 |
ENST00000537887.1
ENST00000417582.2 |
GATAD2A
|
GATA zinc finger domain containing 2A |
| chr5_-_149792295 | 0.09 |
ENST00000518797.1
ENST00000524315.1 ENST00000009530.7 ENST00000377795.3 |
CD74
|
CD74 molecule, major histocompatibility complex, class II invariant chain |
| chr1_+_114473350 | 0.09 |
ENST00000503968.1
|
HIPK1
|
homeodomain interacting protein kinase 1 |
| chr6_-_32908792 | 0.08 |
ENST00000418107.2
|
HLA-DMB
|
major histocompatibility complex, class II, DM beta |
| chr19_+_45417921 | 0.08 |
ENST00000252491.4
ENST00000592885.1 ENST00000589781.1 |
APOC1
|
apolipoprotein C-I |
| chr17_+_38137073 | 0.06 |
ENST00000541736.1
|
PSMD3
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 |
| chr6_-_32557610 | 0.06 |
ENST00000360004.5
|
HLA-DRB1
|
major histocompatibility complex, class II, DR beta 1 |
| chr6_-_32634425 | 0.06 |
ENST00000399082.3
ENST00000399079.3 ENST00000374943.4 ENST00000434651.2 |
HLA-DQB1
|
major histocompatibility complex, class II, DQ beta 1 |
| chr19_+_45418067 | 0.06 |
ENST00000589078.1
ENST00000586638.1 |
APOC1
|
apolipoprotein C-I |
| chr1_+_249132512 | 0.06 |
ENST00000505503.1
|
ZNF672
|
zinc finger protein 672 |
| chr6_+_32812568 | 0.06 |
ENST00000414474.1
|
PSMB9
|
proteasome (prosome, macropain) subunit, beta type, 9 |
| chr6_-_32920794 | 0.06 |
ENST00000395305.3
ENST00000395303.3 ENST00000374843.4 ENST00000429234.1 |
HLA-DMA
XXbac-BPG181M17.5
|
major histocompatibility complex, class II, DM alpha Uncharacterized protein |
| chr6_-_32908765 | 0.06 |
ENST00000416244.2
|
HLA-DMB
|
major histocompatibility complex, class II, DM beta |
| chr3_+_9851558 | 0.05 |
ENST00000430718.1
|
TTLL3
|
tubulin tyrosine ligase-like family, member 3 |
| chr22_-_30987837 | 0.05 |
ENST00000335214.6
|
PES1
|
pescadillo ribosomal biogenesis factor 1 |
| chr17_-_19265982 | 0.05 |
ENST00000268841.6
ENST00000261499.4 ENST00000575478.1 |
B9D1
|
B9 protein domain 1 |
| chr6_-_32821599 | 0.05 |
ENST00000354258.4
|
TAP1
|
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| chr17_+_38137050 | 0.05 |
ENST00000264639.4
|
PSMD3
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 |
| chr6_+_26383318 | 0.05 |
ENST00000469230.1
ENST00000490025.1 ENST00000356709.4 ENST00000352867.2 ENST00000493275.1 ENST00000472507.1 ENST00000482536.1 ENST00000432533.2 ENST00000482842.1 |
BTN2A2
|
butyrophilin, subfamily 2, member A2 |
| chr12_-_110841462 | 0.05 |
ENST00000455511.3
ENST00000450008.2 |
ANAPC7
|
anaphase promoting complex subunit 7 |
| chrX_+_19362011 | 0.05 |
ENST00000379806.5
ENST00000545074.1 ENST00000540249.1 ENST00000423505.1 ENST00000417819.1 ENST00000422285.2 ENST00000355808.5 ENST00000379805.3 |
PDHA1
|
pyruvate dehydrogenase (lipoamide) alpha 1 |
| chr7_+_766320 | 0.05 |
ENST00000297440.6
ENST00000313147.5 |
HEATR2
|
HEAT repeat containing 2 |
| chr19_+_19496624 | 0.04 |
ENST00000494516.2
ENST00000360315.3 ENST00000252577.5 |
GATAD2A
|
GATA zinc finger domain containing 2A |
| chr5_+_119799927 | 0.04 |
ENST00000407149.2
ENST00000379551.2 |
PRR16
|
proline rich 16 |
| chr16_+_67381263 | 0.04 |
ENST00000541146.1
ENST00000563189.1 ENST00000290940.7 |
LRRC36
|
leucine rich repeat containing 36 |
| chr6_-_30658745 | 0.04 |
ENST00000376420.5
ENST00000376421.5 |
NRM
|
nurim (nuclear envelope membrane protein) |
| chr11_+_66624527 | 0.04 |
ENST00000393952.3
|
LRFN4
|
leucine rich repeat and fibronectin type III domain containing 4 |
| chr22_+_44576770 | 0.04 |
ENST00000444313.3
ENST00000416291.1 |
PARVG
|
parvin, gamma |
| chr10_+_14880364 | 0.04 |
ENST00000441647.1
|
HSPA14
|
heat shock 70kDa protein 14 |
| chr5_-_55412774 | 0.03 |
ENST00000434982.2
|
ANKRD55
|
ankyrin repeat domain 55 |
| chr4_-_143226979 | 0.03 |
ENST00000514525.1
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa |
| chr4_-_143227088 | 0.03 |
ENST00000511838.1
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa |
| chr10_+_14880157 | 0.03 |
ENST00000378372.3
|
HSPA14
|
heat shock 70kDa protein 14 |
| chr1_-_208417620 | 0.03 |
ENST00000367033.3
|
PLXNA2
|
plexin A2 |
| chr19_-_51014345 | 0.03 |
ENST00000391815.3
ENST00000594350.1 ENST00000601423.1 |
JOSD2
|
Josephin domain containing 2 |
| chr16_+_57844549 | 0.03 |
ENST00000564282.1
|
CTD-2600O9.1
|
uncharacterized protein LOC388282 |
| chr1_+_249132462 | 0.03 |
ENST00000306562.3
|
ZNF672
|
zinc finger protein 672 |
| chr10_-_14880002 | 0.03 |
ENST00000465530.1
|
CDNF
|
cerebral dopamine neurotrophic factor |
| chr6_-_133079022 | 0.02 |
ENST00000525289.1
ENST00000326499.6 |
VNN2
|
vanin 2 |
| chr16_+_67381289 | 0.02 |
ENST00000435835.3
|
LRRC36
|
leucine rich repeat containing 36 |
| chr6_+_26365387 | 0.02 |
ENST00000532865.1
ENST00000530653.1 ENST00000527417.1 |
BTN3A2
|
butyrophilin, subfamily 3, member A2 |
| chr1_-_202936394 | 0.02 |
ENST00000367249.4
|
CYB5R1
|
cytochrome b5 reductase 1 |
| chr3_+_196466710 | 0.02 |
ENST00000327134.3
|
PAK2
|
p21 protein (Cdc42/Rac)-activated kinase 2 |
| chr2_-_201599892 | 0.02 |
ENST00000452787.1
|
AC007163.3
|
AC007163.3 |
| chr6_-_30181156 | 0.02 |
ENST00000418026.1
ENST00000416596.1 ENST00000453195.1 |
TRIM26
|
tripartite motif containing 26 |
| chr4_+_88529681 | 0.02 |
ENST00000399271.1
|
DSPP
|
dentin sialophosphoprotein |
| chr3_+_9851384 | 0.02 |
ENST00000419081.1
ENST00000438596.1 ENST00000417065.1 ENST00000439814.1 ENST00000418745.1 |
TTLL3
|
tubulin tyrosine ligase-like family, member 3 |
| chr13_-_47012325 | 0.02 |
ENST00000409879.2
|
KIAA0226L
|
KIAA0226-like |
| chr11_-_118436707 | 0.02 |
ENST00000264020.2
ENST00000264021.3 |
IFT46
|
intraflagellar transport 46 homolog (Chlamydomonas) |
| chr3_-_169587621 | 0.01 |
ENST00000523069.1
ENST00000316428.5 ENST00000264676.5 |
LRRC31
|
leucine rich repeat containing 31 |
| chr2_+_173600565 | 0.01 |
ENST00000397081.3
|
RAPGEF4
|
Rap guanine nucleotide exchange factor (GEF) 4 |
| chr3_+_66271489 | 0.01 |
ENST00000536651.1
|
SLC25A26
|
solute carrier family 25 (S-adenosylmethionine carrier), member 26 |
| chr8_+_101170134 | 0.01 |
ENST00000520643.1
|
SPAG1
|
sperm associated antigen 1 |
| chr8_+_101170257 | 0.00 |
ENST00000251809.3
|
SPAG1
|
sperm associated antigen 1 |
| chr2_-_242088850 | 0.00 |
ENST00000358649.4
ENST00000452907.1 ENST00000403638.3 ENST00000539818.1 ENST00000415234.1 ENST00000234040.4 |
PASK
|
PAS domain containing serine/threonine kinase |
| chr2_+_173600514 | 0.00 |
ENST00000264111.6
|
RAPGEF4
|
Rap guanine nucleotide exchange factor (GEF) 4 |
| chr19_+_10563567 | 0.00 |
ENST00000344979.3
|
PDE4A
|
phosphodiesterase 4A, cAMP-specific |
| chr1_-_79472365 | 0.00 |
ENST00000370742.3
|
ELTD1
|
EGF, latrophilin and seven transmembrane domain containing 1 |
| chr9_+_43135095 | 0.00 |
ENST00000377437.2
|
AL513478.1
|
Uncharacterized protein |
Network of associatons between targets according to the STRING database.
First level regulatory network of RFX5
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0002399 | MHC class II protein complex assembly(GO:0002399) |
| 0.0 | 0.1 | GO:0010900 | negative regulation of phosphatidylcholine catabolic process(GO:0010900) |
| 0.0 | 0.1 | GO:0002906 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 0.0 | 0.2 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 0.0 | 0.1 | GO:0046967 | cytosol to ER transport(GO:0046967) |
| 0.0 | 0.1 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.0 | 0.1 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
| 0.0 | 0.5 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 0.1 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0070736 | protein-glycine ligase activity, initiating(GO:0070736) |
| 0.0 | 0.1 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.0 | 0.2 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 0.0 | 0.0 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.0 | 0.1 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.0 | 0.1 | GO:0052828 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
| 0.0 | 0.3 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.4 | GO:0042605 | peptide antigen binding(GO:0042605) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |