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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RUNX1_RUNX2

Z-value: 1.38

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Transcription factors associated with RUNX1_RUNX2

Gene Symbol Gene ID Gene Info
RUNX1
ENSG00000159216.14 RUNX family transcription factor 1
RUNX2
ENSG00000124813.16 RUNX family transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RUNX1hg19_v2_chr21_-_36259445_362595190.739.7e-02Click!
RUNX2hg19_v2_chr6_+_45390222_45390298-0.315.5e-01Click!

Activity profile of RUNX1_RUNX2 motif

Sorted Z-values of RUNX1_RUNX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_1606513 1.64 ENST00000382171.2
KRTAP5-1
keratin associated protein 5-1
chr1_-_235098935 1.13 ENST00000423175.1
RP11-443B7.1
RP11-443B7.1
chr1_+_149239529 1.12 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr6_-_152623231 0.84 ENST00000540663.1
ENST00000537033.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr19_+_56989609 0.79 ENST00000601875.1
ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr22_+_21996549 0.77 ENST00000248958.4
SDF2L1
stromal cell-derived factor 2-like 1
chr10_+_104221137 0.63 ENST00000366277.2
ENST00000238936.4
ENST00000369931.3
TMEM180
transmembrane protein 180
chr11_-_64885111 0.62 ENST00000528598.1
ENST00000310597.4
ZNHIT2
zinc finger, HIT-type containing 2
chr18_+_52385068 0.59 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr17_+_78193443 0.58 ENST00000577155.1
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr15_-_72668805 0.56 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr17_+_73780852 0.56 ENST00000589666.1
UNK
unkempt family zinc finger
chr11_-_1771797 0.55 ENST00000340134.4
IFITM10
interferon induced transmembrane protein 10
chr6_+_159071015 0.54 ENST00000360448.3
SYTL3
synaptotagmin-like 3
chrX_-_54209640 0.51 ENST00000375180.2
ENST00000328235.4
ENST00000477084.1
FAM120C
family with sequence similarity 120C
chr19_+_36134528 0.51 ENST00000591135.1
ETV2
ets variant 2
chr3_+_14058794 0.49 ENST00000424053.1
ENST00000528067.1
ENST00000429201.1
TPRXL
tetra-peptide repeat homeobox-like
chr3_-_131756559 0.48 ENST00000505957.1
CPNE4
copine IV
chr15_-_49170219 0.47 ENST00000558220.1
ENST00000537958.1
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr8_+_144640499 0.47 ENST00000525721.1
ENST00000534018.1
GSDMD
gasdermin D
chr12_-_4754318 0.47 ENST00000536414.1
AKAP3
A kinase (PRKA) anchor protein 3
chr1_+_209929446 0.47 ENST00000479796.1
TRAF3IP3
TRAF3 interacting protein 3
chr2_+_136499287 0.47 ENST00000415164.1
UBXN4
UBX domain protein 4
chr16_-_75467274 0.45 ENST00000566254.1
CFDP1
craniofacial development protein 1
chr19_-_18391708 0.45 ENST00000600972.1
JUND
jun D proto-oncogene
chr7_+_17414360 0.45 ENST00000419463.1
AC019117.1
AC019117.1
chr4_-_184243561 0.43 ENST00000514470.1
ENST00000541814.1
CLDN24
claudin 24
chr16_+_81772633 0.43 ENST00000566191.1
ENST00000565272.1
ENST00000563954.1
ENST00000565054.1
RP11-960L18.1
PLCG2
RP11-960L18.1
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr6_+_45296391 0.42 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr2_-_61389168 0.42 ENST00000607743.1
ENST00000605902.1
RP11-493E12.1
RP11-493E12.1
chr12_-_48276710 0.42 ENST00000550314.1
VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
chr11_+_2923423 0.41 ENST00000312221.5
SLC22A18
solute carrier family 22, member 18
chr20_-_45530365 0.41 ENST00000414085.1
RP11-323C15.2
RP11-323C15.2
chr1_+_179051160 0.41 ENST00000367625.4
ENST00000352445.6
TOR3A
torsin family 3, member A
chr20_+_54987305 0.41 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr17_+_2264983 0.40 ENST00000574650.1
SGSM2
small G protein signaling modulator 2
chr11_+_2923499 0.40 ENST00000449793.2
SLC22A18
solute carrier family 22, member 18
chr19_+_3708338 0.39 ENST00000590545.1
TJP3
tight junction protein 3
chr3_-_169482840 0.38 ENST00000602385.1
TERC
telomerase RNA component
chr5_-_180018540 0.37 ENST00000292641.3
SCGB3A1
secretoglobin, family 3A, member 1
chr12_+_47610315 0.37 ENST00000548348.1
ENST00000549500.1
PCED1B
PC-esterase domain containing 1B
chr1_-_147632428 0.36 ENST00000599640.1
BX842679.1
Uncharacterized protein FLJ46360
chr11_+_7559485 0.36 ENST00000527790.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr14_-_50506589 0.36 ENST00000553914.2
RP11-58E21.3
RP11-58E21.3
chr19_-_6415695 0.35 ENST00000594496.1
ENST00000594745.1
ENST00000600480.1
KHSRP
KH-type splicing regulatory protein
chr5_-_138861926 0.35 ENST00000510817.1
TMEM173
transmembrane protein 173
chr16_+_27226256 0.34 ENST00000567735.1
KDM8
lysine (K)-specific demethylase 8
chr12_-_4754356 0.34 ENST00000540967.1
AKAP3
A kinase (PRKA) anchor protein 3
chr5_-_108063949 0.33 ENST00000606054.1
LINC01023
long intergenic non-protein coding RNA 1023
chr11_-_104480019 0.33 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chrX_-_55208866 0.32 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr14_+_62037287 0.32 ENST00000556569.1
RP11-47I22.3
Uncharacterized protein
chr2_+_37571717 0.32 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr17_+_1633755 0.31 ENST00000545662.1
WDR81
WD repeat domain 81
chr7_+_134832808 0.30 ENST00000275767.3
TMEM140
transmembrane protein 140
chr2_-_207078086 0.30 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr6_+_31515337 0.30 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr4_-_84035868 0.30 ENST00000426923.2
ENST00000509973.1
PLAC8
placenta-specific 8
chr21_+_17909594 0.29 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chr15_-_74494779 0.29 ENST00000571341.1
STRA6
stimulated by retinoic acid 6
chr12_-_96793142 0.29 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17
chr19_+_48969094 0.29 ENST00000595676.1
CTC-273B12.7
Uncharacterized protein
chr5_+_172386517 0.28 ENST00000519522.1
RPL26L1
ribosomal protein L26-like 1
chr22_+_23264766 0.28 ENST00000390331.2
IGLC7
immunoglobulin lambda constant 7
chr14_-_90097910 0.27 ENST00000550332.2
RP11-944C7.1
Protein LOC100506792
chr19_-_30199516 0.27 ENST00000591243.1
C19orf12
chromosome 19 open reading frame 12
chr4_-_84035905 0.27 ENST00000311507.4
PLAC8
placenta-specific 8
chr5_-_94417562 0.27 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chrX_+_153238220 0.27 ENST00000425274.1
TMEM187
transmembrane protein 187
chr15_+_41057818 0.27 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr19_+_9203855 0.27 ENST00000429566.3
OR1M1
olfactory receptor, family 1, subfamily M, member 1
chr7_+_154720173 0.27 ENST00000397551.2
PAXIP1-AS2
PAXIP1 antisense RNA 2
chr7_+_117119187 0.26 ENST00000446805.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr12_+_25205155 0.26 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr1_+_152748848 0.26 ENST00000334371.2
LCE1F
late cornified envelope 1F
chr7_-_96654133 0.26 ENST00000486603.2
ENST00000222598.4
DLX5
distal-less homeobox 5
chr21_-_33957805 0.25 ENST00000300258.3
ENST00000472557.1
TCP10L
t-complex 10-like
chrX_-_106960285 0.25 ENST00000503515.1
ENST00000372397.2
TSC22D3
TSC22 domain family, member 3
chr8_+_58890917 0.25 ENST00000522992.1
RP11-1112C15.1
RP11-1112C15.1
chr9_+_34653861 0.25 ENST00000556792.1
ENST00000318041.9
ENST00000378817.4
IL11RA
interleukin 11 receptor, alpha
chr19_+_35899569 0.25 ENST00000600405.1
AC002511.1
AC002511.1
chr11_-_62358972 0.25 ENST00000278279.3
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chr10_+_43916052 0.25 ENST00000442526.2
RP11-517P14.2
RP11-517P14.2
chr19_+_4769117 0.25 ENST00000540211.1
ENST00000317292.3
ENST00000586721.1
ENST00000592709.1
ENST00000588711.1
ENST00000589639.1
ENST00000591008.1
ENST00000592663.1
ENST00000588758.1
MIR7-3HG
MIR7-3 host gene (non-protein coding)
chr1_-_25291475 0.25 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr6_+_13272904 0.25 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr9_+_136287444 0.25 ENST00000355699.2
ENST00000356589.2
ENST00000371911.3
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr1_+_149871171 0.25 ENST00000369150.1
BOLA1
bolA family member 1
chrX_-_153744434 0.25 ENST00000369643.1
ENST00000393572.1
FAM3A
family with sequence similarity 3, member A
chr12_+_7055631 0.24 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr14_-_81425828 0.24 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr14_+_100531738 0.24 ENST00000555706.1
EVL
Enah/Vasp-like
chr15_-_56757329 0.24 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr16_-_425205 0.24 ENST00000448854.1
TMEM8A
transmembrane protein 8A
chr11_+_65337901 0.24 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
SSSCA1
Sjogren syndrome/scleroderma autoantigen 1
chr8_+_31496809 0.24 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chrX_+_84258832 0.24 ENST00000373173.2
APOOL
apolipoprotein O-like
chr16_-_71918033 0.24 ENST00000425432.1
ENST00000313565.6
ENST00000568666.1
ENST00000562797.1
ENST00000564134.1
ZNF821
zinc finger protein 821
chr19_+_3708376 0.24 ENST00000539908.2
TJP3
tight junction protein 3
chr6_+_24126350 0.24 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
NRSN1
neurensin 1
chr5_-_159766528 0.24 ENST00000505287.2
CCNJL
cyclin J-like
chr17_+_79008940 0.23 ENST00000392411.3
ENST00000575989.1
ENST00000321280.7
ENST00000428708.2
ENST00000575712.1
ENST00000575245.1
ENST00000435091.3
ENST00000321300.6
BAIAP2
BAI1-associated protein 2
chr8_-_146078376 0.23 ENST00000533270.1
ENST00000305103.3
ENST00000402718.3
COMMD5
COMM domain containing 5
chr20_+_54987168 0.23 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr9_-_35563896 0.23 ENST00000399742.2
FAM166B
family with sequence similarity 166, member B
chr11_-_61124776 0.23 ENST00000542361.1
CYB561A3
cytochrome b561 family, member A3
chr22_+_39868786 0.23 ENST00000429402.1
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr6_+_31514622 0.23 ENST00000376146.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr1_-_23521222 0.23 ENST00000374619.1
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr2_+_183943464 0.23 ENST00000354221.4
DUSP19
dual specificity phosphatase 19
chr20_+_48789121 0.23 ENST00000411453.1
RP11-112L6.4
RP11-112L6.4
chr11_-_45940343 0.23 ENST00000532681.1
PEX16
peroxisomal biogenesis factor 16
chr1_+_47264711 0.23 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
CYP4B1
cytochrome P450, family 4, subfamily B, polypeptide 1
chr14_+_75988768 0.22 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr7_+_2685164 0.22 ENST00000400376.2
TTYH3
tweety family member 3
chr17_+_19281034 0.22 ENST00000308406.5
ENST00000299612.7
MAPK7
mitogen-activated protein kinase 7
chrX_-_1331527 0.22 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
CRLF2
cytokine receptor-like factor 2
chr9_+_131902283 0.22 ENST00000436883.1
ENST00000414510.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr19_+_39647271 0.22 ENST00000599657.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr16_+_20911174 0.22 ENST00000568663.1
LYRM1
LYR motif containing 1
chr11_+_34999328 0.21 ENST00000526309.1
PDHX
pyruvate dehydrogenase complex, component X
chr17_+_79935418 0.21 ENST00000306729.7
ENST00000306739.4
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr1_+_149754227 0.21 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr1_-_917497 0.21 ENST00000433179.2
C1orf170
chromosome 1 open reading frame 170
chr2_+_149402009 0.21 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr2_+_242498135 0.21 ENST00000318407.3
BOK
BCL2-related ovarian killer
chr15_+_73976715 0.21 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276
CD276 molecule
chrX_+_47441712 0.21 ENST00000218388.4
ENST00000377018.2
ENST00000456754.2
ENST00000377017.1
ENST00000441738.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr4_+_88896819 0.21 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr19_+_58987786 0.21 ENST00000335841.4
ZNF446
zinc finger protein 446
chr8_+_22436635 0.21 ENST00000452226.1
ENST00000397760.4
ENST00000339162.7
ENST00000397761.2
PDLIM2
PDZ and LIM domain 2 (mystique)
chr11_+_826136 0.21 ENST00000528315.1
ENST00000533803.1
EFCAB4A
EF-hand calcium binding domain 4A
chr7_-_7782204 0.21 ENST00000418534.2
AC007161.5
AC007161.5
chr17_-_39123144 0.21 ENST00000355612.2
KRT39
keratin 39
chr1_+_66999799 0.20 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr16_-_28608424 0.20 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr4_-_140223614 0.20 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr6_-_31745085 0.20 ENST00000375686.3
ENST00000447450.1
VWA7
von Willebrand factor A domain containing 7
chr19_+_42580274 0.20 ENST00000359044.4
ZNF574
zinc finger protein 574
chr11_-_61124711 0.20 ENST00000536915.1
CYB561A3
cytochrome b561 family, member A3
chr1_+_149871135 0.20 ENST00000369152.5
BOLA1
bolA family member 1
chrX_+_54947229 0.20 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO
trophinin
chr7_-_76955563 0.19 ENST00000441833.2
GSAP
gamma-secretase activating protein
chr1_-_168464875 0.19 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr11_-_66103932 0.19 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr11_-_65321198 0.19 ENST00000530426.1
LTBP3
latent transforming growth factor beta binding protein 3
chr19_+_39897943 0.19 ENST00000600033.1
ZFP36
ZFP36 ring finger protein
chr3_+_187957646 0.19 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr10_+_124739964 0.19 ENST00000406217.2
PSTK
phosphoseryl-tRNA kinase
chr5_-_180230830 0.19 ENST00000427865.2
ENST00000514283.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr9_+_4839762 0.19 ENST00000448872.2
ENST00000441844.1
RCL1
RNA terminal phosphate cyclase-like 1
chrX_-_108976449 0.19 ENST00000469857.1
ACSL4
acyl-CoA synthetase long-chain family member 4
chr11_+_1860200 0.19 ENST00000381911.1
TNNI2
troponin I type 2 (skeletal, fast)
chr11_-_796197 0.19 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr17_-_4806369 0.19 ENST00000293780.4
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
chr11_+_6411636 0.19 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr2_+_234826016 0.19 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr17_+_26833250 0.19 ENST00000577936.1
ENST00000579795.1
FOXN1
forkhead box N1
chr19_-_10946949 0.19 ENST00000214869.2
ENST00000591695.1
TMED1
transmembrane emp24 protein transport domain containing 1
chr11_-_62379752 0.19 ENST00000466671.1
ENST00000466886.1
EML3
echinoderm microtubule associated protein like 3
chr3_-_100566492 0.19 ENST00000528490.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr8_-_96281419 0.19 ENST00000286688.5
C8orf37
chromosome 8 open reading frame 37
chr22_+_31031639 0.19 ENST00000343605.4
ENST00000300385.8
SLC35E4
solute carrier family 35, member E4
chr7_-_44105158 0.18 ENST00000297283.3
PGAM2
phosphoglycerate mutase 2 (muscle)
chr7_-_102715172 0.18 ENST00000456695.1
ENST00000455112.2
ENST00000440067.1
FBXL13
F-box and leucine-rich repeat protein 13
chr8_+_27169138 0.18 ENST00000522338.1
PTK2B
protein tyrosine kinase 2 beta
chr22_-_50913371 0.18 ENST00000348911.6
ENST00000380817.3
ENST00000390679.3
SBF1
SET binding factor 1
chr17_+_27895609 0.18 ENST00000581411.2
ENST00000301057.7
TP53I13
tumor protein p53 inducible protein 13
chr6_+_27925019 0.18 ENST00000244623.1
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr17_-_36884451 0.18 ENST00000595377.1
AC006449.1
NS5ATP13TP1; Uncharacterized protein
chr1_+_152758690 0.18 ENST00000368771.1
ENST00000368770.3
LCE1E
late cornified envelope 1E
chrX_-_78622805 0.18 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr17_+_6916957 0.18 ENST00000547302.2
RNASEK-C17orf49
RNASEK-C17orf49 readthrough
chr22_-_43411106 0.18 ENST00000453643.1
ENST00000263246.3
ENST00000337959.4
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr10_+_48359344 0.18 ENST00000412534.1
ENST00000444585.1
ZNF488
zinc finger protein 488
chr12_-_109025849 0.18 ENST00000228463.6
SELPLG
selectin P ligand
chr17_-_19281203 0.18 ENST00000487415.2
B9D1
B9 protein domain 1
chr4_+_71091786 0.18 ENST00000317987.5
FDCSP
follicular dendritic cell secreted protein
chr1_-_21948906 0.18 ENST00000374761.2
ENST00000599760.1
RAP1GAP
RAP1 GTPase activating protein
chr10_+_81891416 0.18 ENST00000372270.2
PLAC9
placenta-specific 9
chr14_+_100531615 0.18 ENST00000392920.3
EVL
Enah/Vasp-like
chr17_+_37821593 0.18 ENST00000578283.1
TCAP
titin-cap
chr11_+_62379194 0.18 ENST00000525801.1
ENST00000534093.1
ROM1
retinal outer segment membrane protein 1
chr19_+_14017116 0.17 ENST00000589606.1
CC2D1A
coiled-coil and C2 domain containing 1A
chr22_+_21400229 0.17 ENST00000342608.4
ENST00000543388.1
ENST00000442047.1
AC002472.13
Leucine-rich repeat-containing protein LOC400891
chr1_+_17634689 0.17 ENST00000375453.1
ENST00000375448.4
PADI4
peptidyl arginine deiminase, type IV
chr1_-_45805752 0.17 ENST00000354383.6
ENST00000355498.2
ENST00000372100.5
ENST00000531105.1
MUTYH
mutY homolog
chr3_+_122399697 0.17 ENST00000494811.1
PARP14
poly (ADP-ribose) polymerase family, member 14
chr17_+_73455788 0.17 ENST00000581519.1
KIAA0195
KIAA0195
chr10_-_375422 0.17 ENST00000434695.2
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr5_-_154230130 0.17 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chr19_+_41509851 0.17 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr22_-_24241117 0.17 ENST00000406213.1
AP000350.4
Uncharacterized protein
chr10_-_10836919 0.17 ENST00000602763.1
ENST00000415590.2
ENST00000434919.2
SFTA1P
surfactant associated 1, pseudogene
chr14_+_62331592 0.17 ENST00000554436.1
CTD-2277K2.1
CTD-2277K2.1
chr21_+_30502806 0.17 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr9_-_131486367 0.17 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr11_-_108093329 0.17 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr2_-_28113217 0.17 ENST00000444339.2
RBKS
ribokinase
chrX_-_100129128 0.17 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX1_RUNX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.4 GO:0038183 bile acid signaling pathway(GO:0038183)
0.1 0.4 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.4 GO:0070376 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.1 0.8 GO:0046618 drug export(GO:0046618)
0.1 0.5 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.4 GO:0002316 follicular B cell differentiation(GO:0002316)
0.1 0.3 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.4 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.5 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.3 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.2 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.4 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.2 GO:2000861 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.3 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.2 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.1 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.2 GO:1904597 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.1 0.5 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.2 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.9 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.2 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.2 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.2 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.0 GO:0035482 gastric motility(GO:0035482) gastric emptying(GO:0035483)
0.0 0.2 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:0019046 release from viral latency(GO:0019046)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.5 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.4 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.1 GO:1901899 positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.0 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.1 GO:0050904 diapedesis(GO:0050904)
0.0 0.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.2 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.2 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.0 0.2 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.2 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.1 GO:0032827 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.1 GO:0044035 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.2 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0 0.3 GO:0045007 depurination(GO:0045007)
0.0 0.6 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.5 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.1 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0042412 taurine biosynthetic process(GO:0042412)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.2 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.1 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.2 GO:0048619 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.2 GO:0035864 response to potassium ion(GO:0035864)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.1 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 1.1 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.2 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.2 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.0 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.1 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.5 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0035905 inhibition of neuroepithelial cell differentiation(GO:0002085) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.1 GO:0061502 uropod organization(GO:0032796) early endosome to recycling endosome transport(GO:0061502)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.3 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.0 GO:0043318 regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.2 GO:0070836 caveola assembly(GO:0070836)
0.0 0.0 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.1 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.0 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.0 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.2 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.0 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.1 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.0 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.0 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.3 GO:0036376 sodium ion export from cell(GO:0036376)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.0 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.0 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0036034 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.0 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.0 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.0 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.0 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419) positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.0 GO:2000542 negative regulation of endodermal cell differentiation(GO:1903225) negative regulation of gastrulation(GO:2000542)
0.0 0.1 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.5 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.4 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.1 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 1.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.0 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.0 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.4 GO:0038181 bile acid receptor activity(GO:0038181)
0.1 0.4 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.3 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.3 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.3 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.3 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.3 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.2 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.2 GO:0033677 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.5 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.5 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0004402 histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0047726 iron-cytochrome-c reductase activity(GO:0047726)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.1 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.0 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.6 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.0 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.0 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.0 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.0 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.1 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.1 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.0 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex