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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX6

Z-value: 0.54

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Transcription factors associated with SOX6

Gene Symbol Gene ID Gene Info
SOX6
ENSG00000110693.11 SRY-box transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX6hg19_v2_chr11_-_16419067_164191080.295.8e-01Click!

Activity profile of SOX6 motif

Sorted Z-values of SOX6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_166702601 0.60 ENST00000428888.1
AC009495.4
AC009495.4
chr10_-_75351088 0.36 ENST00000451492.1
ENST00000413442.1
USP54
ubiquitin specific peptidase 54
chr12_-_58145889 0.30 ENST00000547853.1
CDK4
cyclin-dependent kinase 4
chr6_+_13272904 0.29 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr16_-_3068171 0.28 ENST00000572154.1
ENST00000328796.4
CLDN6
claudin 6
chr13_+_51913819 0.21 ENST00000419898.2
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr6_-_127840048 0.21 ENST00000467753.1
SOGA3
SOGA family member 3
chr12_-_11508520 0.20 ENST00000545626.1
ENST00000500254.2
PRB1
proline-rich protein BstNI subfamily 1
chr1_+_152943122 0.19 ENST00000328051.2
SPRR4
small proline-rich protein 4
chr2_-_114647327 0.19 ENST00000602760.1
RP11-141B14.1
RP11-141B14.1
chr4_-_186732892 0.19 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2
sorbin and SH3 domain containing 2
chr17_+_76037081 0.18 ENST00000588549.1
TNRC6C
trinucleotide repeat containing 6C
chr20_-_52645231 0.18 ENST00000448484.1
BCAS1
breast carcinoma amplified sequence 1
chr12_+_95611536 0.16 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr2_-_231989808 0.16 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr12_-_11548496 0.15 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr3_-_69402828 0.15 ENST00000460709.1
FRMD4B
FERM domain containing 4B
chr6_+_32936942 0.15 ENST00000496118.2
BRD2
bromodomain containing 2
chr12_-_8815299 0.15 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr12_+_95611569 0.15 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
VEZT
vezatin, adherens junctions transmembrane protein
chr12_+_11905413 0.14 ENST00000545027.1
ETV6
ets variant 6
chr8_-_11660077 0.14 ENST00000533405.1
RP11-297N6.4
Uncharacterized protein
chr17_+_1666108 0.13 ENST00000570731.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_-_17571722 0.13 ENST00000301944.2
NXNL1
nucleoredoxin-like 1
chr2_-_208031542 0.12 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr11_-_85430356 0.12 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr20_-_1317555 0.12 ENST00000537552.1
AL136531.1
HCG2043693; Uncharacterized protein
chr22_+_37959647 0.12 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr4_-_68620053 0.12 ENST00000420975.2
ENST00000226413.4
GNRHR
gonadotropin-releasing hormone receptor
chr6_-_31782813 0.11 ENST00000375654.4
HSPA1L
heat shock 70kDa protein 1-like
chr6_-_167040693 0.11 ENST00000366863.2
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_+_95611516 0.11 ENST00000436874.1
VEZT
vezatin, adherens junctions transmembrane protein
chr20_-_39317868 0.11 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr4_-_186732048 0.11 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr4_-_105416039 0.11 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr13_-_41593425 0.11 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr4_-_186732241 0.11 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr22_+_39052632 0.11 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1
chibby homolog 1 (Drosophila)
chr17_+_72667239 0.10 ENST00000402449.4
RAB37
RAB37, member RAS oncogene family
chr1_+_14075903 0.10 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PRDM2
PR domain containing 2, with ZNF domain
chr3_-_114790179 0.10 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_4773205 0.10 ENST00000440139.1
CDYL
chromodomain protein, Y-like
chr18_+_7946839 0.10 ENST00000578916.1
PTPRM
protein tyrosine phosphatase, receptor type, M
chr4_+_54243917 0.10 ENST00000507166.1
FIP1L1
factor interacting with PAPOLA and CPSF1
chr3_-_52719888 0.10 ENST00000458294.1
PBRM1
polybromo 1
chr12_+_124997766 0.10 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr11_-_75236867 0.09 ENST00000376282.3
ENST00000336898.3
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr17_-_56065484 0.09 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chrX_+_107068959 0.09 ENST00000451923.1
MID2
midline 2
chr12_-_58146048 0.09 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4
cyclin-dependent kinase 4
chr4_+_26322987 0.09 ENST00000505958.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr16_+_15528332 0.09 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr3_-_167813672 0.09 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr3_-_167813132 0.09 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr3_+_186649133 0.09 ENST00000417392.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr15_+_89631647 0.09 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2
abhydrolase domain containing 2
chrX_+_80457442 0.09 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr4_+_54243798 0.08 ENST00000337488.6
ENST00000358575.5
ENST00000507922.1
FIP1L1
factor interacting with PAPOLA and CPSF1
chr11_-_10830463 0.08 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr11_+_46402482 0.08 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr10_+_22605304 0.08 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr18_+_13218769 0.08 ENST00000399848.3
ENST00000361205.4
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr11_+_125496619 0.08 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr12_+_25205628 0.08 ENST00000554942.1
LRMP
lymphoid-restricted membrane protein
chr11_-_82708435 0.08 ENST00000525117.1
ENST00000532548.1
RAB30
RAB30, member RAS oncogene family
chr3_+_181429704 0.08 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr18_+_3451646 0.08 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr16_+_30406423 0.08 ENST00000524644.1
ZNF48
zinc finger protein 48
chr5_+_140254884 0.08 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr3_+_52719936 0.08 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr19_-_59030921 0.08 ENST00000354590.3
ENST00000596739.1
ZBTB45
zinc finger and BTB domain containing 45
chr12_+_9066472 0.08 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr11_-_125365435 0.08 ENST00000524435.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr11_-_76155618 0.08 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr4_-_109089573 0.08 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr12_-_8815215 0.08 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr11_+_46402583 0.08 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr12_-_104359475 0.07 ENST00000553183.1
C12orf73
chromosome 12 open reading frame 73
chr4_-_109090106 0.07 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chr4_+_54243862 0.07 ENST00000306932.6
FIP1L1
factor interacting with PAPOLA and CPSF1
chr22_+_32439019 0.07 ENST00000266088.4
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr11_-_8892464 0.07 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5
suppression of tumorigenicity 5
chr21_-_40720995 0.07 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chr11_-_79151695 0.07 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr10_-_13390270 0.07 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1
selenophosphate synthetase 1
chr6_+_32937083 0.07 ENST00000456339.1
BRD2
bromodomain containing 2
chr2_-_208890218 0.07 ENST00000457206.1
ENST00000427836.2
ENST00000389247.4
PLEKHM3
pleckstrin homology domain containing, family M, member 3
chr5_+_140792614 0.07 ENST00000398610.2
PCDHGA10
protocadherin gamma subfamily A, 10
chr2_-_204399976 0.07 ENST00000457812.1
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr17_+_9066252 0.07 ENST00000436734.1
NTN1
netrin 1
chr1_+_14075865 0.06 ENST00000413440.1
PRDM2
PR domain containing 2, with ZNF domain
chr4_+_89300158 0.06 ENST00000502870.1
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr5_+_140235469 0.06 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr11_-_82708519 0.06 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr11_+_63754294 0.06 ENST00000543988.1
OTUB1
OTU domain, ubiquitin aldehyde binding 1
chr15_+_80696666 0.06 ENST00000303329.4
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr16_+_23765948 0.06 ENST00000300113.2
CHP2
calcineurin-like EF-hand protein 2
chr11_+_63753883 0.06 ENST00000538426.1
ENST00000543004.1
OTUB1
OTU domain, ubiquitin aldehyde binding 1
chr17_+_30813576 0.06 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr17_-_76719638 0.06 ENST00000587308.1
CYTH1
cytohesin 1
chr7_-_150924121 0.06 ENST00000441774.1
ENST00000222388.2
ENST00000287844.2
ABCF2
ATP-binding cassette, sub-family F (GCN20), member 2
chr15_+_57211318 0.06 ENST00000557947.1
TCF12
transcription factor 12
chr2_-_70475586 0.06 ENST00000416149.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr17_+_67498396 0.06 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr5_+_140593509 0.06 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr8_+_42195972 0.06 ENST00000532157.1
ENST00000265421.4
ENST00000520008.1
POLB
polymerase (DNA directed), beta
chr1_-_151431674 0.06 ENST00000531094.1
POGZ
pogo transposable element with ZNF domain
chr5_+_140213815 0.06 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr14_-_91884150 0.06 ENST00000553403.1
CCDC88C
coiled-coil domain containing 88C
chr4_-_186877481 0.06 ENST00000444781.1
ENST00000432655.1
SORBS2
sorbin and SH3 domain containing 2
chr11_-_64013663 0.06 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_-_62414070 0.06 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chr16_+_89989687 0.06 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
TUBB3
Tubulin beta-3 chain
chr9_+_112852477 0.06 ENST00000480388.1
AKAP2
A kinase (PRKA) anchor protein 2
chr1_+_47799542 0.06 ENST00000471289.2
ENST00000450808.2
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr2_+_65215604 0.06 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chrX_+_135579670 0.05 ENST00000218364.4
HTATSF1
HIV-1 Tat specific factor 1
chr14_+_103851712 0.05 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3
MAP/microtubule affinity-regulating kinase 3
chr3_+_39509163 0.05 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chr19_+_49468558 0.05 ENST00000331825.6
FTL
ferritin, light polypeptide
chr2_-_47572207 0.05 ENST00000441997.1
AC073283.4
AC073283.4
chr18_+_55102917 0.05 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr3_-_8686479 0.05 ENST00000544814.1
ENST00000427408.1
SSUH2
ssu-2 homolog (C. elegans)
chr7_+_139528952 0.05 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr12_-_109219937 0.05 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr11_+_131781290 0.05 ENST00000425719.2
ENST00000374784.1
NTM
neurotrimin
chr2_-_207078086 0.05 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr18_-_52989217 0.05 ENST00000570287.2
TCF4
transcription factor 4
chr7_+_87563557 0.05 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22
ADAM metallopeptidase domain 22
chr12_+_32260085 0.05 ENST00000548411.1
ENST00000281474.5
ENST00000551086.1
BICD1
bicaudal D homolog 1 (Drosophila)
chr6_-_24877490 0.05 ENST00000540914.1
ENST00000378023.4
FAM65B
family with sequence similarity 65, member B
chr7_-_107643567 0.05 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
LAMB1
laminin, beta 1
chr2_-_70475730 0.05 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr17_+_21729593 0.05 ENST00000581769.1
ENST00000584755.1
UBBP4
ubiquitin B pseudogene 4
chr5_-_176037105 0.05 ENST00000303991.4
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr20_-_3996036 0.05 ENST00000336095.6
RNF24
ring finger protein 24
chr12_-_18890940 0.05 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1
phospholipase C, zeta 1
chr17_+_1945301 0.05 ENST00000572195.1
OVCA2
ovarian tumor suppressor candidate 2
chr3_-_57583130 0.05 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr8_+_11660227 0.05 ENST00000443614.2
ENST00000525900.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr15_-_54025300 0.05 ENST00000559418.1
WDR72
WD repeat domain 72
chr6_-_127840021 0.05 ENST00000465909.2
SOGA3
SOGA family member 3
chr4_-_185726906 0.05 ENST00000513317.1
ACSL1
acyl-CoA synthetase long-chain family member 1
chr4_+_55524085 0.05 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr3_+_39509070 0.05 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr20_-_20693131 0.05 ENST00000202677.7
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr12_-_58145604 0.05 ENST00000552254.1
CDK4
cyclin-dependent kinase 4
chr16_+_54964740 0.05 ENST00000394636.4
IRX5
iroquois homeobox 5
chr19_-_18717627 0.05 ENST00000392386.3
CRLF1
cytokine receptor-like factor 1
chr1_-_26232951 0.05 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr5_-_157002775 0.05 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chrX_-_117107542 0.04 ENST00000371878.1
KLHL13
kelch-like family member 13
chr12_-_58146128 0.04 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4
cyclin-dependent kinase 4
chr11_+_46402744 0.04 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr6_-_109776901 0.04 ENST00000431946.1
MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr2_-_85641162 0.04 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
CAPG
capping protein (actin filament), gelsolin-like
chrX_+_70503433 0.04 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO
non-POU domain containing, octamer-binding
chr19_+_58694742 0.04 ENST00000597528.1
ENST00000594839.1
ZNF274
zinc finger protein 274
chr1_-_212004090 0.04 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr2_+_61293021 0.04 ENST00000402291.1
KIAA1841
KIAA1841
chr21_+_33784670 0.04 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chr10_+_123923105 0.04 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chrX_+_12993202 0.04 ENST00000451311.2
ENST00000380636.1
TMSB4X
thymosin beta 4, X-linked
chr1_+_249200395 0.04 ENST00000355360.4
ENST00000329291.5
ENST00000539153.1
PGBD2
piggyBac transposable element derived 2
chr15_+_79166065 0.04 ENST00000559690.1
ENST00000559158.1
MORF4L1
mortality factor 4 like 1
chr10_+_35415851 0.04 ENST00000374726.3
CREM
cAMP responsive element modulator
chr10_-_128975273 0.04 ENST00000424811.2
FAM196A
family with sequence similarity 196, member A
chr21_-_33104367 0.04 ENST00000286835.7
ENST00000399804.1
SCAF4
SR-related CTD-associated factor 4
chr9_-_98269481 0.04 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1
patched 1
chr7_+_73868439 0.04 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr7_-_107643674 0.04 ENST00000222399.6
LAMB1
laminin, beta 1
chr1_-_207143802 0.04 ENST00000324852.4
ENST00000400962.3
FCAMR
Fc receptor, IgA, IgM, high affinity
chr11_-_44971702 0.04 ENST00000533940.1
ENST00000533937.1
TP53I11
tumor protein p53 inducible protein 11
chr12_-_45269769 0.04 ENST00000548826.1
NELL2
NEL-like 2 (chicken)
chr2_-_225266743 0.04 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chr1_-_32801825 0.04 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr7_+_99699179 0.04 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr10_+_104535994 0.04 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr14_+_100070869 0.04 ENST00000502101.2
RP11-543C4.1
RP11-543C4.1
chr12_-_109797249 0.04 ENST00000538041.1
RP11-256L11.1
RP11-256L11.1
chr15_+_90744745 0.04 ENST00000558051.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr6_-_29527702 0.04 ENST00000377050.4
UBD
ubiquitin D
chr18_+_3449821 0.04 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr6_-_134639180 0.04 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chrX_+_65384052 0.04 ENST00000336279.5
ENST00000458621.1
HEPH
hephaestin
chr16_+_30406721 0.04 ENST00000320159.2
ZNF48
zinc finger protein 48
chr12_+_50479101 0.04 ENST00000551966.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr1_-_6479963 0.04 ENST00000377836.4
ENST00000487437.1
ENST00000489730.1
ENST00000377834.4
HES2
hes family bHLH transcription factor 2
chr4_-_140477910 0.04 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chrX_-_106959631 0.04 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr6_+_13925098 0.04 ENST00000488300.1
ENST00000544682.1
ENST00000420478.2
RNF182
ring finger protein 182
chr1_-_26324534 0.04 ENST00000374284.1
ENST00000441420.1
ENST00000374282.3
PAFAH2
platelet-activating factor acetylhydrolase 2, 40kDa
chr12_-_105478339 0.04 ENST00000424857.2
ENST00000258494.9
ALDH1L2
aldehyde dehydrogenase 1 family, member L2
chr7_+_99006232 0.03 ENST00000403633.2
BUD31
BUD31 homolog (S. cerevisiae)
chr8_+_11660120 0.03 ENST00000220584.4
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr22_+_38004723 0.03 ENST00000381756.5
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr12_+_50898881 0.03 ENST00000301180.5
DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr10_+_24528108 0.03 ENST00000438429.1
KIAA1217
KIAA1217
chr11_+_64949343 0.03 ENST00000279247.6
ENST00000532285.1
ENST00000534373.1
CAPN1
calpain 1, (mu/I) large subunit
chr3_+_112930306 0.03 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.1 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.0 GO:0007343 egg activation(GO:0007343)
0.0 0.0 GO:0038162 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.0 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.0 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.0 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.4 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.0 GO:1904204 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0039713 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors