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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX8

Z-value: 0.75

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Transcription factors associated with SOX8

Gene Symbol Gene ID Gene Info
SOX8
ENSG00000005513.9 SRY-box transcription factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX8hg19_v2_chr16_+_1031762_1031808-0.138.1e-01Click!

Activity profile of SOX8 motif

Sorted Z-values of SOX8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153029980 0.69 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr1_+_153330322 0.65 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr11_+_18154059 0.61 ENST00000531264.1
MRGPRX3
MAS-related GPR, member X3
chr12_+_113354341 0.60 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_+_13677795 0.56 ENST00000434509.1
AC092635.1
AC092635.1
chr14_+_95078714 0.56 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr1_+_81106951 0.51 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr1_+_152956549 0.48 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr8_+_125283924 0.44 ENST00000517482.1
RP11-383J24.1
RP11-383J24.1
chr22_-_30642728 0.42 ENST00000403987.3
LIF
leukemia inhibitory factor
chr10_-_4285835 0.34 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr2_-_25451065 0.34 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr14_-_21562671 0.33 ENST00000554923.1
ZNF219
zinc finger protein 219
chr2_-_36779411 0.33 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr12_-_96793142 0.32 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17
chr15_+_91445448 0.31 ENST00000558290.1
ENST00000558853.1
ENST00000559999.1
MAN2A2
mannosidase, alpha, class 2A, member 2
chr17_-_43339474 0.28 ENST00000331780.4
SPATA32
spermatogenesis associated 32
chr16_+_82068830 0.28 ENST00000199936.4
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr16_+_82068873 0.26 ENST00000566213.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr8_-_11873043 0.26 ENST00000527396.1
RP11-481A20.11
Protein LOC101060662
chr22_-_50708781 0.26 ENST00000449719.2
ENST00000330651.6
MAPK11
mitogen-activated protein kinase 11
chr16_-_28503357 0.25 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr3_-_54962100 0.23 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr4_+_22999152 0.22 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr3_-_193272741 0.22 ENST00000392443.3
ATP13A4
ATPase type 13A4
chr2_-_214017151 0.22 ENST00000452786.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr1_-_200992827 0.22 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr20_-_5426380 0.22 ENST00000609252.1
ENST00000422352.1
LINC00658
long intergenic non-protein coding RNA 658
chr15_+_45938079 0.21 ENST00000561493.1
SQRDL
sulfide quinone reductase-like (yeast)
chr7_+_6714599 0.21 ENST00000328239.7
ENST00000542006.1
AC073343.1
Uncharacterized protein
chrX_+_18725758 0.21 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr4_+_75174204 0.21 ENST00000332112.4
ENST00000514968.1
ENST00000503098.1
ENST00000502358.1
ENST00000509145.1
ENST00000505212.1
EPGN
epithelial mitogen
chr10_-_75676400 0.20 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chr22_+_45714301 0.20 ENST00000427777.1
FAM118A
family with sequence similarity 118, member A
chr2_+_219646462 0.20 ENST00000258415.4
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr10_-_4285923 0.20 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr6_-_131211534 0.20 ENST00000456097.2
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr18_-_73967160 0.20 ENST00000579714.1
RP11-94B19.7
RP11-94B19.7
chr5_+_89770696 0.20 ENST00000504930.1
ENST00000514483.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr19_-_21950332 0.19 ENST00000598026.1
ZNF100
zinc finger protein 100
chr7_+_6713376 0.19 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
AC073343.1
Uncharacterized protein
chr3_-_100558953 0.19 ENST00000533795.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr17_+_39421591 0.19 ENST00000391355.1
KRTAP9-6
keratin associated protein 9-6
chr10_-_101825151 0.19 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr11_-_9482010 0.19 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr11_+_12308447 0.18 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr12_-_50101165 0.18 ENST00000352151.5
ENST00000335154.5
ENST00000293590.5
FMNL3
formin-like 3
chr17_-_27230035 0.18 ENST00000378895.4
ENST00000394901.3
DHRS13
dehydrogenase/reductase (SDR family) member 13
chr6_-_133079022 0.18 ENST00000525289.1
ENST00000326499.6
VNN2
vanin 2
chr5_+_118788138 0.18 ENST00000256216.6
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr12_-_12714025 0.18 ENST00000539940.1
DUSP16
dual specificity phosphatase 16
chr19_+_1269324 0.17 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
CIRBP
cold inducible RNA binding protein
chr19_-_6333614 0.17 ENST00000301452.4
ACER1
alkaline ceramidase 1
chr15_+_45926919 0.17 ENST00000561735.1
ENST00000260324.7
SQRDL
sulfide quinone reductase-like (yeast)
chr5_+_89770664 0.17 ENST00000503973.1
ENST00000399107.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr10_+_9012087 0.17 ENST00000456526.1
RP11-428L9.2
RP11-428L9.2
chr17_-_43339453 0.17 ENST00000543122.1
SPATA32
spermatogenesis associated 32
chr17_+_2240916 0.17 ENST00000574563.1
SGSM2
small G protein signaling modulator 2
chr17_-_41132410 0.17 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr4_+_9446156 0.16 ENST00000334879.1
DEFB131
defensin, beta 131
chr11_-_125366089 0.16 ENST00000366139.3
ENST00000278919.3
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr2_+_135596106 0.16 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr20_-_1472029 0.16 ENST00000359801.3
SIRPB2
signal-regulatory protein beta 2
chr2_-_228497888 0.15 ENST00000264387.4
ENST00000409066.1
C2orf83
chromosome 2 open reading frame 83
chr14_+_75745477 0.15 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr11_+_57435219 0.14 ENST00000527985.1
ENST00000287169.3
ZDHHC5
zinc finger, DHHC-type containing 5
chr12_-_50101003 0.14 ENST00000550488.1
FMNL3
formin-like 3
chr6_+_80129989 0.14 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr16_-_65106110 0.14 ENST00000562882.1
ENST00000567934.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr4_+_89299994 0.14 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr3_+_49711391 0.14 ENST00000296456.5
ENST00000449966.1
APEH
acylaminoacyl-peptide hydrolase
chr7_+_18548878 0.13 ENST00000456174.2
HDAC9
histone deacetylase 9
chr14_-_68159152 0.13 ENST00000554035.1
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr12_+_24857397 0.13 ENST00000536131.1
RP11-625L16.1
RP11-625L16.1
chr20_+_48807351 0.13 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr3_+_38347427 0.13 ENST00000273173.4
SLC22A14
solute carrier family 22, member 14
chr2_+_204801471 0.13 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chr5_-_68339648 0.13 ENST00000479830.2
CTC-498J12.1
CTC-498J12.1
chr10_-_74114714 0.13 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DNAJB12
DnaJ (Hsp40) homolog, subfamily B, member 12
chr4_-_137020391 0.13 ENST00000569694.1
RP11-775H9.3
RP11-775H9.3
chr12_-_49581152 0.13 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr14_+_32963433 0.13 ENST00000554410.1
AKAP6
A kinase (PRKA) anchor protein 6
chr9_-_128246769 0.13 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr7_+_18548924 0.12 ENST00000524023.1
HDAC9
histone deacetylase 9
chr4_-_70518941 0.12 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr16_+_57769635 0.12 ENST00000379661.3
ENST00000562592.1
ENST00000566726.1
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr6_+_42018614 0.12 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr3_+_98216448 0.12 ENST00000427338.1
OR5K2
olfactory receptor, family 5, subfamily K, member 2
chr12_-_123201337 0.12 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr9_-_130661916 0.12 ENST00000373142.1
ENST00000373146.1
ENST00000373144.3
ST6GALNAC6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_-_203274418 0.12 ENST00000457348.1
RP11-134P9.1
long intergenic non-protein coding RNA 1136
chr17_+_7387677 0.12 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr1_+_38512799 0.12 ENST00000432922.1
ENST00000428151.1
RP5-884C9.2
RP5-884C9.2
chr15_+_81299370 0.12 ENST00000560091.1
C15orf26
chromosome 15 open reading frame 26
chr10_-_81932771 0.12 ENST00000437799.1
ANXA11
annexin A11
chr16_+_87636474 0.11 ENST00000284262.2
JPH3
junctophilin 3
chr7_-_92855762 0.11 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr18_+_71815743 0.11 ENST00000169551.6
ENST00000580087.1
TIMM21
translocase of inner mitochondrial membrane 21 homolog (yeast)
chr2_+_33359473 0.11 ENST00000432635.1
LTBP1
latent transforming growth factor beta binding protein 1
chr2_-_159237472 0.11 ENST00000409187.1
CCDC148
coiled-coil domain containing 148
chr17_+_22022437 0.11 ENST00000540040.1
MTRNR2L1
MT-RNR2-like 1
chrX_+_49091920 0.11 ENST00000376227.3
CCDC22
coiled-coil domain containing 22
chr2_-_3584430 0.11 ENST00000438482.1
ENST00000422961.1
AC108488.4
AC108488.4
chr5_-_160279207 0.11 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr1_-_183538319 0.11 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr1_+_66820058 0.11 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr16_+_57392684 0.11 ENST00000219235.4
CCL22
chemokine (C-C motif) ligand 22
chr12_+_48876275 0.11 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr20_-_47804894 0.11 ENST00000371828.3
ENST00000371856.2
ENST00000360426.4
ENST00000347458.5
ENST00000340954.7
ENST00000371802.1
ENST00000371792.1
ENST00000437404.2
STAU1
staufen double-stranded RNA binding protein 1
chr2_-_170550877 0.11 ENST00000447353.1
CCDC173
coiled-coil domain containing 173
chr20_+_32399093 0.11 ENST00000217402.2
CHMP4B
charged multivesicular body protein 4B
chr16_+_30076052 0.11 ENST00000563987.1
ALDOA
aldolase A, fructose-bisphosphate
chr2_+_166326157 0.11 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr16_+_30387141 0.11 ENST00000566955.1
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr4_+_156680153 0.10 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr6_-_76072719 0.10 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr3_+_173116225 0.10 ENST00000457714.1
NLGN1
neuroligin 1
chr4_-_140544386 0.10 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr19_+_39903185 0.10 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr16_+_30075783 0.10 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chr9_+_99690592 0.10 ENST00000354649.3
NUTM2G
NUT family member 2G
chr12_-_11548496 0.10 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr16_+_22308717 0.10 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
POLR3E
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr5_+_140227048 0.10 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr12_-_11508520 0.10 ENST00000545626.1
ENST00000500254.2
PRB1
proline-rich protein BstNI subfamily 1
chr3_-_141719195 0.10 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr2_+_102615416 0.10 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr6_+_31021225 0.10 ENST00000565192.1
ENST00000562344.1
HCG22
HLA complex group 22
chr9_-_113761720 0.10 ENST00000541779.1
ENST00000374430.2
LPAR1
lysophosphatidic acid receptor 1
chr11_+_10477733 0.10 ENST00000528723.1
AMPD3
adenosine monophosphate deaminase 3
chr2_+_97203082 0.10 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr2_+_113816215 0.10 ENST00000346807.3
IL36RN
interleukin 36 receptor antagonist
chr8_-_91095099 0.09 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr19_+_19144384 0.09 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
ARMC6
armadillo repeat containing 6
chr19_+_45681997 0.09 ENST00000433642.2
BLOC1S3
biogenesis of lysosomal organelles complex-1, subunit 3
chr1_+_161475208 0.09 ENST00000367972.4
ENST00000271450.6
FCGR2A
Fc fragment of IgG, low affinity IIa, receptor (CD32)
chr12_+_1099675 0.09 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr16_+_30075595 0.09 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr18_+_32455201 0.09 ENST00000590831.2
DTNA
dystrobrevin, alpha
chr8_+_7752151 0.09 ENST00000302247.2
DEFB4A
defensin, beta 4A
chr16_+_82068585 0.09 ENST00000563491.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr10_-_128110441 0.09 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr13_-_47012325 0.09 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr18_-_5396271 0.09 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr12_-_123187890 0.09 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr12_+_93130311 0.09 ENST00000344636.3
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr2_-_37501692 0.09 ENST00000443977.1
PRKD3
protein kinase D3
chr5_-_146781153 0.09 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr16_+_31271274 0.08 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr3_-_52090461 0.08 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr16_+_87985029 0.08 ENST00000439677.1
ENST00000286122.7
ENST00000355163.5
ENST00000454563.1
ENST00000479780.2
ENST00000393208.2
ENST00000412691.1
ENST00000355022.4
BANP
BTG3 associated nuclear protein
chr6_+_37012607 0.08 ENST00000423336.1
COX6A1P2
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr6_-_138539627 0.08 ENST00000527246.2
PBOV1
prostate and breast cancer overexpressed 1
chr8_+_87111059 0.08 ENST00000285393.3
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr6_-_134638767 0.08 ENST00000524929.1
SGK1
serum/glucocorticoid regulated kinase 1
chr4_+_110769258 0.08 ENST00000594814.1
LRIT3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr9_+_27524283 0.08 ENST00000276943.2
IFNK
interferon, kappa
chr5_+_156887027 0.08 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chr17_-_34207295 0.08 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr7_+_17414360 0.08 ENST00000419463.1
AC019117.1
AC019117.1
chr5_+_140186647 0.08 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr5_-_133510456 0.08 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr11_+_43702322 0.08 ENST00000395700.4
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr18_-_3845293 0.08 ENST00000400145.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr2_-_151344172 0.08 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr6_-_52668605 0.08 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr4_-_10686475 0.07 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr3_-_49851313 0.07 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr3_-_49459878 0.07 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT
aminomethyltransferase
chr5_-_132948216 0.07 ENST00000265342.7
FSTL4
follistatin-like 4
chr18_-_33702078 0.07 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr6_-_32160622 0.07 ENST00000487761.1
ENST00000375040.3
GPSM3
G-protein signaling modulator 3
chr10_-_131762105 0.07 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr2_-_163695128 0.07 ENST00000332142.5
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr14_-_21562648 0.07 ENST00000555270.1
ZNF219
zinc finger protein 219
chr3_+_173302222 0.07 ENST00000361589.4
NLGN1
neuroligin 1
chr11_-_128457446 0.07 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr18_-_29264467 0.07 ENST00000383131.3
ENST00000237019.7
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr14_+_35591928 0.07 ENST00000605870.1
ENST00000557404.3
KIAA0391
KIAA0391
chr7_-_14026123 0.07 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr3_+_154958715 0.07 ENST00000462531.1
ENST00000490497.1
RP11-451G4.1
RP11-451G4.1
chr1_+_182584314 0.07 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr17_-_66951474 0.07 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr10_+_7745232 0.06 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr18_-_3845321 0.06 ENST00000539435.1
ENST00000400147.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr2_-_120124258 0.06 ENST00000409877.1
ENST00000409523.1
ENST00000409466.2
ENST00000414534.1
C2orf76
chromosome 2 open reading frame 76
chr15_+_25101698 0.06 ENST00000400097.1
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr15_+_80733570 0.06 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr10_-_1779663 0.06 ENST00000381312.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr19_-_42806842 0.06 ENST00000596265.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr12_+_58176525 0.06 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr4_-_144940477 0.06 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
GYPB
glycophorin B (MNS blood group)
chr2_-_70944855 0.06 ENST00000415348.1
ADD2
adducin 2 (beta)
chr2_+_170550944 0.06 ENST00000359744.3
ENST00000438838.1
ENST00000438710.1
ENST00000449906.1
ENST00000498202.2
ENST00000272797.4
PHOSPHO2
KLHL23
phosphatase, orphan 2
kelch-like family member 23
chr15_+_62853562 0.06 ENST00000561311.1
TLN2
talin 2
chr8_+_30496078 0.06 ENST00000517349.1
SMIM18
small integral membrane protein 18
chr4_+_156680143 0.06 ENST00000505154.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr10_-_21186144 0.06 ENST00000377119.1
NEBL
nebulette
chr15_+_40674920 0.06 ENST00000416151.2
ENST00000249776.8
KNSTRN
kinetochore-localized astrin/SPAG5 binding protein
chr12_-_76879852 0.06 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.2 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.2 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.3 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0061571 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.1 GO:0072025 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.0 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 1.2 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.0 GO:1902080 negative regulation of calcium-transporting ATPase activity(GO:1901895) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.0 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.0 GO:0052364 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.0 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.0 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0046514 ceramide catabolic process(GO:0046514)
0.0 0.0 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.0 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.1 GO:0052813 phosphatidylinositol 3-kinase activity(GO:0035004) phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.6 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.3 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.2 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.2 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.0 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated