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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SREBF1_TFE3

Z-value: 0.65

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Transcription factors associated with SREBF1_TFE3

Gene Symbol Gene ID Gene Info
SREBF1
ENSG00000072310.12 sterol regulatory element binding transcription factor 1
TFE3
ENSG00000068323.12 transcription factor binding to IGHM enhancer 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SREBF1hg19_v2_chr17_-_17740287_177403160.513.0e-01Click!
TFE3hg19_v2_chrX_-_48901012_48901050-0.354.9e-01Click!

Activity profile of SREBF1_TFE3 motif

Sorted Z-values of SREBF1_TFE3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_72668805 0.88 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr11_-_1785139 0.71 ENST00000236671.2
CTSD
cathepsin D
chr16_-_5083917 0.61 ENST00000312251.3
ENST00000381955.3
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr17_+_42422629 0.58 ENST00000589536.1
ENST00000587109.1
ENST00000587518.1
GRN
granulin
chr17_+_78075361 0.52 ENST00000577106.1
ENST00000390015.3
GAA
glucosidase, alpha; acid
chr19_-_36545649 0.50 ENST00000292894.1
THAP8
THAP domain containing 8
chr17_+_78075498 0.50 ENST00000302262.3
GAA
glucosidase, alpha; acid
chr16_+_28986134 0.49 ENST00000352260.7
SPNS1
spinster homolog 1 (Drosophila)
chr17_-_7137582 0.47 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr7_+_4815238 0.46 ENST00000348624.4
ENST00000401897.1
AP5Z1
adaptor-related protein complex 5, zeta 1 subunit
chr19_+_10812108 0.44 ENST00000250237.5
ENST00000592254.1
QTRT1
queuine tRNA-ribosyltransferase 1
chr4_+_159131596 0.43 ENST00000512481.1
TMEM144
transmembrane protein 144
chr17_+_42422637 0.42 ENST00000053867.3
ENST00000588143.1
GRN
granulin
chr19_-_10764509 0.42 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr17_+_42422662 0.40 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN
granulin
chrX_-_102565932 0.40 ENST00000372674.1
ENST00000372677.3
BEX2
brain expressed X-linked 2
chr17_+_1627834 0.40 ENST00000419248.1
ENST00000418841.1
WDR81
WD repeat domain 81
chr20_-_44519839 0.40 ENST00000372518.4
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr17_+_6915730 0.39 ENST00000548577.1
RNASEK
ribonuclease, RNase K
chr19_+_40873617 0.38 ENST00000599353.1
PLD3
phospholipase D family, member 3
chr4_+_76439095 0.38 ENST00000506261.1
THAP6
THAP domain containing 6
chr16_+_2570431 0.38 ENST00000563556.1
AMDHD2
amidohydrolase domain containing 2
chr19_+_40854559 0.38 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
PLD3
phospholipase D family, member 3
chr22_-_36903069 0.37 ENST00000216187.6
ENST00000423980.1
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr17_+_6915798 0.36 ENST00000402093.1
RNASEK
ribonuclease, RNase K
chr16_+_28986085 0.35 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
SPNS1
spinster homolog 1 (Drosophila)
chr8_-_11660077 0.35 ENST00000533405.1
RP11-297N6.4
Uncharacterized protein
chr16_+_4421841 0.34 ENST00000304735.3
VASN
vasorin
chr16_-_5083589 0.33 ENST00000563578.1
ENST00000562346.2
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr19_-_5680891 0.33 ENST00000309324.4
C19orf70
chromosome 19 open reading frame 70
chr1_-_154193091 0.33 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
C1orf43
chromosome 1 open reading frame 43
chr17_-_7137857 0.33 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr3_-_49395705 0.32 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr11_+_67159416 0.32 ENST00000307980.2
ENST00000544620.1
RAD9A
RAD9 homolog A (S. pombe)
chr6_-_33385870 0.31 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr3_-_49395892 0.31 ENST00000419783.1
GPX1
glutathione peroxidase 1
chr19_-_40854281 0.30 ENST00000392035.2
C19orf47
chromosome 19 open reading frame 47
chr16_-_1525016 0.30 ENST00000262318.8
ENST00000448525.1
CLCN7
chloride channel, voltage-sensitive 7
chr19_-_1237990 0.30 ENST00000382477.2
ENST00000215376.6
ENST00000590083.1
C19orf26
chromosome 19 open reading frame 26
chr16_+_2570340 0.29 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2
amidohydrolase domain containing 2
chr16_-_67514982 0.29 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr17_+_3539744 0.28 ENST00000046640.3
ENST00000381870.3
CTNS
cystinosin, lysosomal cystine transporter
chr9_+_131084846 0.28 ENST00000608951.1
COQ4
coenzyme Q4
chr1_-_156265438 0.27 ENST00000362007.1
C1orf85
chromosome 1 open reading frame 85
chr16_-_28503357 0.27 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr13_+_113951607 0.27 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr17_+_73975292 0.26 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
TEN1
TEN1 CST complex subunit
chr16_-_28503080 0.26 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr20_-_36156264 0.26 ENST00000445723.1
ENST00000414080.1
BLCAP
bladder cancer associated protein
chr15_+_44084040 0.26 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr17_-_76124812 0.25 ENST00000592063.1
ENST00000589271.1
ENST00000322933.4
ENST00000589553.1
TMC6
transmembrane channel-like 6
chr17_+_78075324 0.25 ENST00000570803.1
GAA
glucosidase, alpha; acid
chr11_-_1606513 0.25 ENST00000382171.2
KRTAP5-1
keratin associated protein 5-1
chr5_-_180242576 0.25 ENST00000514438.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr7_+_99746514 0.25 ENST00000341942.5
ENST00000441173.1
LAMTOR4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr9_-_90589402 0.25 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
CDK20
cyclin-dependent kinase 20
chr20_+_44519948 0.25 ENST00000354880.5
ENST00000191018.5
CTSA
cathepsin A
chr6_-_33385854 0.25 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr13_+_113951532 0.24 ENST00000332556.4
LAMP1
lysosomal-associated membrane protein 1
chr7_+_100271446 0.24 ENST00000419828.1
ENST00000427895.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr2_+_242673994 0.24 ENST00000321264.4
ENST00000537090.1
ENST00000403782.1
ENST00000342518.6
D2HGDH
D-2-hydroxyglutarate dehydrogenase
chr3_+_50654821 0.24 ENST00000457064.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr10_+_69644404 0.24 ENST00000212015.6
SIRT1
sirtuin 1
chr20_+_44520009 0.24 ENST00000607482.1
ENST00000372459.2
CTSA
cathepsin A
chr17_-_65992544 0.23 ENST00000580729.1
RP11-855A2.5
RP11-855A2.5
chr16_-_28503327 0.23 ENST00000535392.1
ENST00000395653.4
CLN3
ceroid-lipofuscinosis, neuronal 3
chr3_+_51428704 0.23 ENST00000323686.4
RBM15B
RNA binding motif protein 15B
chr17_+_6915902 0.23 ENST00000570898.1
ENST00000552842.1
RNASEK
ribonuclease, RNase K
chr1_+_153004800 0.23 ENST00000392661.3
SPRR1B
small proline-rich protein 1B
chr10_+_99258625 0.22 ENST00000370664.3
UBTD1
ubiquitin domain containing 1
chr19_-_40854417 0.22 ENST00000582006.1
ENST00000582783.1
C19orf47
chromosome 19 open reading frame 47
chr7_+_100271355 0.22 ENST00000436220.1
ENST00000424361.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr19_-_49016418 0.22 ENST00000270238.3
LMTK3
lemur tyrosine kinase 3
chr22_-_20850128 0.22 ENST00000328879.4
KLHL22
kelch-like family member 22
chr7_-_27196267 0.21 ENST00000242159.3
HOXA7
homeobox A7
chr19_+_7587555 0.21 ENST00000601003.1
MCOLN1
mucolipin 1
chr19_+_7587491 0.21 ENST00000264079.6
MCOLN1
mucolipin 1
chr19_+_10764937 0.21 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr9_-_131709858 0.21 ENST00000372586.3
DOLK
dolichol kinase
chr6_-_44225231 0.21 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
SLC35B2
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr1_+_10093188 0.20 ENST00000377153.1
UBE4B
ubiquitination factor E4B
chrX_-_102565858 0.20 ENST00000449185.1
ENST00000536889.1
BEX2
brain expressed X-linked 2
chr19_+_5681153 0.20 ENST00000579559.1
ENST00000577222.1
HSD11B1L
RPL36
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr2_-_47572207 0.20 ENST00000441997.1
AC073283.4
AC073283.4
chr7_-_27135591 0.20 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr1_-_27682962 0.20 ENST00000486046.1
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr5_-_1112141 0.20 ENST00000264930.5
SLC12A7
solute carrier family 12 (potassium/chloride transporter), member 7
chr5_+_149865377 0.20 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr2_-_220042825 0.19 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr19_-_48018203 0.19 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr8_-_145688231 0.19 ENST00000530374.1
CYHR1
cysteine/histidine-rich 1
chr4_-_113627966 0.19 ENST00000505632.1
RP11-148B6.2
RP11-148B6.2
chr17_+_3539998 0.19 ENST00000452111.1
ENST00000574776.1
ENST00000441220.2
ENST00000414524.2
CTNS
cystinosin, lysosomal cystine transporter
chr16_-_425205 0.19 ENST00000448854.1
TMEM8A
transmembrane protein 8A
chr9_-_90589586 0.19 ENST00000325303.8
ENST00000375883.3
CDK20
cyclin-dependent kinase 20
chr12_+_112451222 0.19 ENST00000552052.1
ERP29
endoplasmic reticulum protein 29
chr16_+_5083950 0.19 ENST00000588623.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr22_+_38203898 0.19 ENST00000323205.6
ENST00000248924.6
ENST00000445195.1
GCAT
glycine C-acetyltransferase
chr11_-_71814422 0.19 ENST00000278671.5
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr19_+_1275917 0.19 ENST00000469144.1
C19orf24
chromosome 19 open reading frame 24
chr12_-_90103077 0.18 ENST00000551310.1
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr2_+_240323439 0.18 ENST00000428471.1
ENST00000413029.1
AC062017.1
Uncharacterized protein
chr5_-_110074603 0.18 ENST00000515278.2
TMEM232
transmembrane protein 232
chr22_-_36903101 0.18 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr1_+_152957707 0.18 ENST00000368762.1
SPRR1A
small proline-rich protein 1A
chr11_-_110968081 0.18 ENST00000603154.1
RP11-89C3.4
RP11-89C3.4
chr19_+_797392 0.18 ENST00000350092.4
ENST00000349038.4
ENST00000586481.1
ENST00000585535.1
PTBP1
polypyrimidine tract binding protein 1
chr16_+_88923494 0.17 ENST00000567895.1
ENST00000301021.3
ENST00000565504.1
ENST00000567312.1
ENST00000568583.1
ENST00000561840.1
TRAPPC2L
trafficking protein particle complex 2-like
chr22_+_21996549 0.17 ENST00000248958.4
SDF2L1
stromal cell-derived factor 2-like 1
chr2_+_120187465 0.17 ENST00000409826.1
ENST00000417645.1
TMEM37
transmembrane protein 37
chr6_-_163834852 0.17 ENST00000604200.1
CAHM
colon adenocarcinoma hypermethylated (non-protein coding)
chr15_-_76352069 0.17 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr17_-_76124711 0.17 ENST00000306591.7
ENST00000590602.1
TMC6
transmembrane channel-like 6
chr17_-_79791118 0.17 ENST00000576431.1
ENST00000575061.1
ENST00000455127.2
ENST00000572645.1
ENST00000538396.1
ENST00000573478.1
FAM195B
family with sequence similarity 195, member B
chr11_-_71814276 0.17 ENST00000538404.1
ENST00000535107.1
ENST00000545249.1
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr12_+_51633061 0.17 ENST00000551313.1
DAZAP2
DAZ associated protein 2
chr17_+_79935418 0.17 ENST00000306729.7
ENST00000306739.4
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr17_-_73851285 0.17 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WBP2
WW domain binding protein 2
chr19_-_3985455 0.17 ENST00000309311.6
EEF2
eukaryotic translation elongation factor 2
chr19_-_36499521 0.17 ENST00000397428.3
ENST00000503121.1
ENST00000340477.5
ENST00000324444.3
ENST00000490730.1
SYNE4
spectrin repeat containing, nuclear envelope family member 4
chr3_-_19988462 0.17 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr7_+_99070527 0.17 ENST00000379724.3
ZNF789
zinc finger protein 789
chr14_-_45431091 0.17 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr5_-_154230130 0.16 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chr1_+_44440575 0.16 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr1_-_155211017 0.16 ENST00000536770.1
ENST00000368373.3
GBA
glucosidase, beta, acid
chr14_+_24458093 0.16 ENST00000558753.1
ENST00000537912.1
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chr19_-_13227534 0.16 ENST00000588229.1
ENST00000357720.4
TRMT1
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr4_-_100242549 0.16 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr20_+_18118486 0.16 ENST00000432901.3
PET117
PET117 homolog (S. cerevisiae)
chr19_+_6464243 0.16 ENST00000600229.1
ENST00000356762.3
CRB3
crumbs homolog 3 (Drosophila)
chr16_+_2098003 0.16 ENST00000439673.2
ENST00000350773.4
TSC2
tuberous sclerosis 2
chr16_+_2097970 0.16 ENST00000382538.6
ENST00000401874.2
ENST00000353929.4
TSC2
tuberous sclerosis 2
chr14_-_94443065 0.15 ENST00000555287.1
ASB2
ankyrin repeat and SOCS box containing 2
chr7_+_100464760 0.15 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr7_+_102073966 0.15 ENST00000495936.1
ENST00000356387.2
ENST00000478730.2
ENST00000468241.1
ENST00000403646.3
ORAI2
ORAI calcium release-activated calcium modulator 2
chr19_-_5720248 0.15 ENST00000360614.3
LONP1
lon peptidase 1, mitochondrial
chr5_-_176730676 0.15 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24
RAB24, member RAS oncogene family
chr12_-_109027643 0.15 ENST00000388962.3
ENST00000550948.1
SELPLG
selectin P ligand
chr19_-_8386238 0.15 ENST00000301457.2
NDUFA7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr2_+_220042933 0.15 ENST00000430297.2
FAM134A
family with sequence similarity 134, member A
chr7_-_150777920 0.15 ENST00000353841.2
ENST00000297532.6
FASTK
Fas-activated serine/threonine kinase
chr9_+_131084815 0.15 ENST00000300452.3
ENST00000609948.1
COQ4
coenzyme Q4
chr19_-_5680499 0.15 ENST00000587589.1
C19orf70
chromosome 19 open reading frame 70
chr4_-_87028478 0.15 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr5_-_175964366 0.15 ENST00000274811.4
RNF44
ring finger protein 44
chr19_-_15236470 0.14 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr11_+_66360665 0.14 ENST00000310190.4
CCS
copper chaperone for superoxide dismutase
chr19_-_40324767 0.14 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr9_-_34665983 0.14 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
RP11-195F19.5
HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr14_-_106068065 0.14 ENST00000390541.2
IGHE
immunoglobulin heavy constant epsilon
chr17_+_37356528 0.14 ENST00000225430.4
RPL19
ribosomal protein L19
chr12_-_108154705 0.14 ENST00000547188.1
PRDM4
PR domain containing 4
chr6_+_87865262 0.14 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr22_-_31536480 0.14 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr1_-_154909329 0.14 ENST00000368467.3
PMVK
phosphomevalonate kinase
chr19_+_6464502 0.14 ENST00000308243.7
CRB3
crumbs homolog 3 (Drosophila)
chr17_+_37356555 0.14 ENST00000579374.1
RPL19
ribosomal protein L19
chr7_+_74379083 0.14 ENST00000361825.7
GATSL1
GATS protein-like 1
chr20_-_2821271 0.14 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr19_-_36545128 0.14 ENST00000538849.1
THAP8
THAP domain containing 8
chr8_-_71157595 0.14 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr6_-_33385902 0.14 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr1_-_101360374 0.14 ENST00000535414.1
EXTL2
exostosin-like glycosyltransferase 2
chr19_-_12833361 0.14 ENST00000592287.1
TNPO2
transportin 2
chr5_-_159739483 0.14 ENST00000519673.1
ENST00000541762.1
CCNJL
cyclin J-like
chr19_-_13227463 0.14 ENST00000437766.1
ENST00000221504.8
TRMT1
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr13_+_36920569 0.13 ENST00000379848.2
SPG20OS
SPG20 opposite strand
chr8_-_145331153 0.13 ENST00000377412.4
KM-PA-2
KM-PA-2 protein; Uncharacterized protein
chr20_+_2821340 0.13 ENST00000380445.3
ENST00000380469.3
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr9_-_91793675 0.13 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr19_-_5340730 0.13 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS
protein tyrosine phosphatase, receptor type, S
chr5_+_140514782 0.13 ENST00000231134.5
PCDHB5
protocadherin beta 5
chrX_+_10126488 0.13 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr19_-_3500635 0.13 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr21_-_38445470 0.13 ENST00000399098.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr12_-_125473600 0.13 ENST00000308736.2
DHX37
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chrX_+_153657009 0.13 ENST00000449556.1
ATP6AP1
ATPase, H+ transporting, lysosomal accessory protein 1
chr12_+_51632666 0.13 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr19_+_40854363 0.13 ENST00000599685.1
ENST00000392032.2
PLD3
phospholipase D family, member 3
chr16_-_75150665 0.12 ENST00000300051.4
ENST00000450168.2
LDHD
lactate dehydrogenase D
chr1_+_92545862 0.12 ENST00000370382.3
ENST00000342818.3
BTBD8
BTB (POZ) domain containing 8
chr19_-_18632861 0.12 ENST00000262809.4
ELL
elongation factor RNA polymerase II
chr16_-_30134441 0.12 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr3_-_122512619 0.12 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr12_+_117176090 0.12 ENST00000257575.4
ENST00000407967.3
ENST00000392549.2
RNFT2
ring finger protein, transmembrane 2
chr3_+_127317066 0.12 ENST00000265056.7
MCM2
minichromosome maintenance complex component 2
chr14_+_105941118 0.12 ENST00000550577.1
ENST00000538259.2
CRIP2
cysteine-rich protein 2
chr11_-_63376013 0.12 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr19_+_12848299 0.12 ENST00000357332.3
ASNA1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr6_+_138188351 0.12 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr19_+_572543 0.12 ENST00000333511.3
ENST00000573216.1
ENST00000353555.4
BSG
basigin (Ok blood group)
chr1_-_155211065 0.12 ENST00000427500.3
GBA
glucosidase, beta, acid
chr3_+_158519654 0.12 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1
major facilitator superfamily domain containing 1
chr22_-_39268308 0.12 ENST00000407418.3
CBX6
chromobox homolog 6
chr6_-_84937314 0.12 ENST00000257766.4
ENST00000403245.3
KIAA1009
KIAA1009
chr6_+_139349903 0.12 ENST00000461027.1
ABRACL
ABRA C-terminal like
chr20_-_2821756 0.12 ENST00000356872.3
ENST00000439542.1
PCED1A
PC-esterase domain containing 1A
chr1_+_11796177 0.12 ENST00000400895.2
ENST00000376629.4
ENST00000376627.2
ENST00000314340.5
ENST00000452018.2
ENST00000510878.1
AGTRAP
angiotensin II receptor-associated protein
chr3_-_20227720 0.12 ENST00000412997.1
SGOL1
shugoshin-like 1 (S. pombe)

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF1_TFE3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0043181 vacuolar sequestering(GO:0043181)
0.2 0.8 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 0.8 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.6 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.1 0.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.3 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.3 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.3 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.7 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.2 GO:0019516 lactate oxidation(GO:0019516)
0.1 0.2 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.1 0.3 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1 0.2 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.2 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.1 0.9 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.3 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.6 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.9 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.2 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.3 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.0 GO:0071873 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.3 GO:0009227 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:2000340 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338) positive regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000340)
0.0 0.0 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.0 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.2 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.1 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.0 0.1 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.1 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.0 GO:0043132 NAD transport(GO:0043132)
0.0 0.9 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.2 GO:0030210 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.0 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.0 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.0 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.3 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.0 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of mitochondrial DNA metabolic process(GO:1901860) response to methionine(GO:1904640)
0.0 0.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.0 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.0 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.0 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.0 GO:0050787 detoxification of mercury ion(GO:0050787)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:2000851 positive regulation of saliva secretion(GO:0046878) positive regulation of glucocorticoid secretion(GO:2000851)
0.0 0.1 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.0 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:1902164 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.0 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.0 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.0 GO:0036090 cleavage furrow ingression(GO:0036090)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.5 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.6 GO:0097413 Lewy body(GO:0097413)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 3.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.0 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.0 GO:0019034 viral replication complex(GO:0019034)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.0 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.3 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 0.9 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.4 GO:0016898 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.1 0.3 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.3 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.9 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.3 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.9 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.2 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.0 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.5 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.8 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.0 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.0 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.4 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.0 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.0 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.0 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.0 GO:0002060 nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism