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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SRF

Z-value: 0.68

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Transcription factors associated with SRF

Gene Symbol Gene ID Gene Info
SRF
ENSG00000112658.6 serum response factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SRFhg19_v2_chr6_+_43139037_431390940.701.2e-01Click!

Activity profile of SRF motif

Sorted Z-values of SRF motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_11907829 0.61 ENST00000376480.3
NPPA
natriuretic peptide A
chr9_+_92219919 0.47 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr5_+_137801160 0.44 ENST00000239938.4
EGR1
early growth response 1
chr22_+_36784632 0.35 ENST00000424761.1
RP4-633O19__A.1
RP4-633O19__A.1
chr20_+_35169885 0.32 ENST00000279022.2
ENST00000346786.2
MYL9
myosin, light chain 9, regulatory
chr4_-_87028478 0.30 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr7_-_94285402 0.28 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr1_+_167599330 0.28 ENST00000367854.3
ENST00000361496.3
RCSD1
RCSD domain containing 1
chr3_-_123339418 0.28 ENST00000583087.1
MYLK
myosin light chain kinase
chr19_-_47975106 0.26 ENST00000539381.1
ENST00000594353.1
ENST00000542837.1
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr8_+_97597148 0.25 ENST00000521590.1
SDC2
syndecan 2
chr3_-_123339343 0.24 ENST00000578202.1
MYLK
myosin light chain kinase
chr7_-_94285472 0.24 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr5_-_142000883 0.24 ENST00000359370.6
FGF1
fibroblast growth factor 1 (acidic)
chr1_+_167599532 0.22 ENST00000537350.1
RCSD1
RCSD domain containing 1
chr8_-_22550815 0.22 ENST00000317216.2
EGR3
early growth response 3
chr8_-_101964738 0.20 ENST00000523938.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr13_-_46742630 0.20 ENST00000416500.1
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_54372877 0.20 ENST00000414489.1
MYADM
myeloid-associated differentiation marker
chr7_-_94285511 0.19 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr2_-_31030277 0.19 ENST00000534090.2
ENST00000295055.8
CAPN13
calpain 13
chr3_+_49027308 0.18 ENST00000383729.4
ENST00000343546.4
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr10_-_64576105 0.18 ENST00000242480.3
ENST00000411732.1
EGR2
early growth response 2
chr20_-_62258394 0.18 ENST00000370077.1
GMEB2
glucocorticoid modulatory element binding protein 2
chr2_-_139259244 0.17 ENST00000414911.1
ENST00000431985.1
AC097721.2
AC097721.2
chr19_+_13135386 0.16 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr8_+_1993173 0.16 ENST00000523438.1
MYOM2
myomesin 2
chr17_-_42875115 0.14 ENST00000591137.1
CTC-296K1.4
CTC-296K1.4
chr19_-_47975417 0.14 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr7_-_559853 0.14 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr22_-_39150947 0.14 ENST00000411587.2
ENST00000420859.1
ENST00000452294.1
ENST00000456894.1
SUN2
Sad1 and UNC84 domain containing 2
chr5_-_169816638 0.13 ENST00000521859.1
ENST00000274629.4
KCNMB1
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr14_-_74226961 0.13 ENST00000286523.5
ENST00000435371.1
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chr15_+_74218787 0.12 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr3_+_187930719 0.12 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr19_+_13135439 0.12 ENST00000586873.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr8_+_1993152 0.12 ENST00000262113.4
MYOM2
myomesin 2
chr1_-_89591749 0.12 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr9_-_98269481 0.11 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1
patched 1
chr6_+_27107053 0.10 ENST00000354348.2
HIST1H4I
histone cluster 1, H4i
chr2_-_106015491 0.10 ENST00000408995.1
ENST00000393353.3
ENST00000322142.8
FHL2
four and a half LIM domains 2
chr7_+_94285637 0.10 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr2_-_106054952 0.10 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr9_-_35691017 0.09 ENST00000378292.3
TPM2
tropomyosin 2 (beta)
chr10_-_90712520 0.09 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr19_-_36247910 0.09 ENST00000587965.1
ENST00000004982.3
HSPB6
heat shock protein, alpha-crystallin-related, B6
chr19_+_2476116 0.09 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr12_+_75874580 0.08 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr9_+_131644781 0.08 ENST00000259324.5
LRRC8A
leucine rich repeat containing 8 family, member A
chr22_+_38004473 0.08 ENST00000414350.3
ENST00000343632.4
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr19_+_54372693 0.08 ENST00000391768.2
MYADM
myeloid-associated differentiation marker
chr10_-_17659357 0.08 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr15_+_96873921 0.08 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr19_+_16177826 0.08 ENST00000589897.1
TPM4
tropomyosin 4
chr1_+_219347203 0.08 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr7_+_143078379 0.08 ENST00000449630.1
ENST00000457235.1
ZYX
zyxin
chr2_-_231989808 0.07 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr7_+_143078652 0.07 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr3_-_9834375 0.07 ENST00000343450.2
ENST00000301964.2
TADA3
transcriptional adaptor 3
chr1_+_219347186 0.07 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr10_-_17659234 0.07 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr5_+_150404904 0.07 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr19_+_13134772 0.07 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr19_+_52102540 0.07 ENST00000601315.1
AC018755.17
AC018755.17
chr19_+_1026298 0.07 ENST00000263097.4
CNN2
calponin 2
chr12_+_52445191 0.07 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr10_+_123922941 0.07 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr3_-_9834463 0.07 ENST00000439043.1
TADA3
transcriptional adaptor 3
chr19_+_57901208 0.06 ENST00000366197.5
ENST00000596282.1
ENST00000597400.1
ENST00000598895.1
ENST00000336128.7
ENST00000596617.1
ZNF548
AC003002.6
zinc finger protein 548
Uncharacterized protein
chr3_+_187930491 0.06 ENST00000443217.1
LPP
LIM domain containing preferred translocation partner in lipoma
chrX_-_153602991 0.06 ENST00000369850.3
ENST00000422373.1
FLNA
filamin A, alpha
chr17_+_73452695 0.06 ENST00000582186.1
ENST00000582455.1
ENST00000581252.1
ENST00000579208.1
KIAA0195
KIAA0195
chr10_+_88428206 0.06 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3
LIM domain binding 3
chr19_+_45971246 0.06 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr11_-_102323740 0.06 ENST00000398136.2
TMEM123
transmembrane protein 123
chr6_+_43139037 0.06 ENST00000265354.4
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr17_-_79481666 0.06 ENST00000575659.1
ACTG1
actin, gamma 1
chr15_+_83776324 0.06 ENST00000379390.6
ENST00000379386.4
ENST00000565774.1
ENST00000565982.1
TM6SF1
transmembrane 6 superfamily member 1
chr7_-_121944491 0.05 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr6_-_123958051 0.05 ENST00000546248.1
TRDN
triadin
chr10_-_29923893 0.05 ENST00000355867.4
SVIL
supervillin
chr1_-_91487806 0.05 ENST00000361321.5
ZNF644
zinc finger protein 644
chr14_+_75745477 0.05 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr6_-_88411911 0.05 ENST00000257787.5
AKIRIN2
akirin 2
chr7_-_27183263 0.05 ENST00000222726.3
HOXA5
homeobox A5
chr19_+_1026566 0.05 ENST00000348419.3
ENST00000565096.2
ENST00000562958.2
ENST00000562075.2
ENST00000607102.1
CNN2
calponin 2
chr2_-_106015527 0.05 ENST00000344213.4
ENST00000358129.4
FHL2
four and a half LIM domains 2
chr19_+_54372639 0.05 ENST00000391769.2
MYADM
myeloid-associated differentiation marker
chr8_-_22550691 0.05 ENST00000519492.1
EGR3
early growth response 3
chr17_+_42634844 0.05 ENST00000315323.3
FZD2
frizzled family receptor 2
chr22_+_38004723 0.05 ENST00000381756.5
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr22_+_45714672 0.05 ENST00000424557.1
FAM118A
family with sequence similarity 118, member A
chr2_-_209118974 0.05 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr5_+_92919043 0.05 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr22_-_50216853 0.04 ENST00000342989.5
ENST00000542442.1
BRD1
bromodomain containing 1
chr5_-_53606396 0.04 ENST00000504924.1
ENST00000507646.2
ENST00000502271.1
ARL15
ADP-ribosylation factor-like 15
chr16_+_4666475 0.04 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr8_-_143696833 0.04 ENST00000356613.2
ARC
activity-regulated cytoskeleton-associated protein
chr6_-_111804905 0.04 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr5_-_111093167 0.04 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr19_+_57901326 0.04 ENST00000596400.1
AC003002.6
Uncharacterized protein
chr9_-_79520989 0.04 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2
prune homolog 2 (Drosophila)
chr2_-_161056762 0.04 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr9_+_36136700 0.04 ENST00000396613.3
ENST00000377959.1
ENST00000377960.4
GLIPR2
GLI pathogenesis-related 2
chr17_+_33474826 0.04 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B
unc-45 homolog B (C. elegans)
chr17_+_3379284 0.03 ENST00000263080.2
ASPA
aspartoacylase
chr1_+_47881744 0.03 ENST00000335071.2
FOXE3
forkhead box E3
chr12_+_59989791 0.03 ENST00000552432.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chrX_-_11284095 0.03 ENST00000303025.6
ENST00000534860.1
ARHGAP6
Rho GTPase activating protein 6
chr8_+_53850991 0.03 ENST00000331251.3
NPBWR1
neuropeptides B/W receptor 1
chr11_-_57282349 0.03 ENST00000528450.1
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr2_-_112237835 0.03 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chrX_+_22056165 0.03 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr19_-_17356697 0.03 ENST00000291442.3
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr4_-_109087906 0.03 ENST00000515500.1
LEF1
lymphoid enhancer-binding factor 1
chr12_+_4382917 0.03 ENST00000261254.3
CCND2
cyclin D2
chr12_+_75874460 0.03 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr12_-_11548496 0.03 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr17_-_10560619 0.03 ENST00000583535.1
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
chr3_+_9834758 0.03 ENST00000485273.1
ENST00000433034.1
ENST00000397256.1
ARPC4
ARPC4-TTLL3
actin related protein 2/3 complex, subunit 4, 20kDa
ARPC4-TTLL3 readthrough
chr2_-_172087824 0.03 ENST00000521943.1
TLK1
tousled-like kinase 1
chr14_+_105266933 0.03 ENST00000555360.1
ZBTB42
zinc finger and BTB domain containing 42
chr12_+_62654119 0.02 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr11_-_47374246 0.02 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
MYBPC3
myosin binding protein C, cardiac
chr5_-_176923803 0.02 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr14_+_74034310 0.02 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr12_-_50616382 0.02 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr2_-_161056802 0.02 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr17_+_7487146 0.02 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr2_-_96811170 0.02 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr6_+_158402860 0.02 ENST00000367122.2
ENST00000367121.3
ENST00000355585.4
ENST00000367113.4
SYNJ2
synaptojanin 2
chr6_-_16761678 0.02 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr5_-_124080203 0.02 ENST00000504926.1
ZNF608
zinc finger protein 608
chr22_+_38004832 0.02 ENST00000405147.3
ENST00000429218.1
ENST00000325180.8
ENST00000337437.4
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr5_-_33892046 0.02 ENST00000352040.3
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr5_+_137774706 0.02 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
REEP2
receptor accessory protein 2
chr12_-_50616122 0.01 ENST00000552823.1
ENST00000552909.1
LIMA1
LIM domain and actin binding 1
chr2_+_191792376 0.01 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr1_-_168106536 0.01 ENST00000537209.1
ENST00000361697.2
ENST00000546300.1
ENST00000367835.1
GPR161
G protein-coupled receptor 161
chr2_-_161264385 0.01 ENST00000409972.1
RBMS1
RNA binding motif, single stranded interacting protein 1
chr9_+_124088860 0.01 ENST00000373806.1
GSN
gelsolin
chr15_-_55581954 0.01 ENST00000336787.1
RAB27A
RAB27A, member RAS oncogene family
chr19_-_35166604 0.01 ENST00000601241.1
SCGB2B2
secretoglobin, family 2B, member 2
chr3_+_9834179 0.01 ENST00000498623.2
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr13_+_27825706 0.01 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
RPL21
ribosomal protein L21
chr5_-_130868688 0.01 ENST00000504575.1
ENST00000513227.1
RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr1_+_11994715 0.01 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
PLOD1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr22_-_36357671 0.01 ENST00000408983.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr10_+_88428370 0.01 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3
LIM domain binding 3
chr7_+_88388628 0.00 ENST00000333190.4
ZNF804B
zinc finger protein 804B
chr19_+_48958766 0.00 ENST00000342291.2
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr22_-_36850991 0.00 ENST00000442579.1
RP5-1119A7.14
RP5-1119A7.14
chrX_-_103499602 0.00 ENST00000372588.4
ESX1
ESX homeobox 1
chr11_-_102323489 0.00 ENST00000361236.3
TMEM123
transmembrane protein 123
chr4_-_83934078 0.00 ENST00000505397.1
LIN54
lin-54 homolog (C. elegans)
chr6_-_159466042 0.00 ENST00000338313.5
TAGAP
T-cell activation RhoGTPase activating protein
chr4_-_109087445 0.00 ENST00000512172.1
LEF1
lymphoid enhancer-binding factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SRF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.6 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.1 0.2 GO:0035284 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.3 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:1903412 response to bile acid(GO:1903412)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.5 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0060849 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.2 GO:1904847 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.1 GO:0010513 regulation of phosphatidylinositol biosynthetic process(GO:0010511) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.6 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.0 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.0 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.6 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression