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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for STAT1_STAT3_BCL6

Z-value: 0.80

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Transcription factors associated with STAT1_STAT3_BCL6

Gene Symbol Gene ID Gene Info
STAT1
ENSG00000115415.14 signal transducer and activator of transcription 1
STAT3
ENSG00000168610.10 signal transducer and activator of transcription 3
BCL6
ENSG00000113916.13 BCL6 transcription repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT3hg19_v2_chr17_-_40540377_40540481-0.552.6e-01Click!
STAT1hg19_v2_chr2_-_191878874_191878976-0.503.2e-01Click!
BCL6hg19_v2_chr3_-_187455680_187455732-0.483.3e-01Click!

Activity profile of STAT1_STAT3_BCL6 motif

Sorted Z-values of STAT1_STAT3_BCL6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_6625605 1.02 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr3_-_50649192 0.87 ENST00000443053.2
ENST00000348721.3
CISH
cytokine inducible SH2-containing protein
chr17_+_6347761 0.58 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A
family with sequence similarity 64, member A
chr12_-_15082050 0.50 ENST00000540097.1
ERP27
endoplasmic reticulum protein 27
chr10_+_6625733 0.49 ENST00000607982.1
ENST00000608526.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr11_+_57531292 0.41 ENST00000524579.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr10_+_35484793 0.36 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr3_+_50649302 0.35 ENST00000446044.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr16_-_8955601 0.31 ENST00000569398.1
ENST00000568968.1
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr10_-_128110441 0.30 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr11_+_76493294 0.28 ENST00000533752.1
TSKU
tsukushi, small leucine rich proteoglycan
chr12_+_122064398 0.26 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr11_-_104817919 0.26 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr5_-_140013224 0.25 ENST00000498971.2
CD14
CD14 molecule
chr12_+_53443963 0.24 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr12_+_53443680 0.21 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr12_-_7244469 0.21 ENST00000538050.1
ENST00000536053.2
C1R
complement component 1, r subcomponent
chr5_-_140013275 0.21 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chrX_-_154563889 0.21 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr3_+_122399697 0.20 ENST00000494811.1
PARP14
poly (ADP-ribose) polymerase family, member 14
chr16_-_67260691 0.20 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29
leucine rich repeat containing 29
chr17_-_41132088 0.19 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr5_-_146781153 0.19 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr9_+_70971815 0.17 ENST00000396392.1
ENST00000396396.1
PGM5
phosphoglucomutase 5
chr2_+_87754989 0.17 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr6_+_26104104 0.17 ENST00000377803.2
HIST1H4C
histone cluster 1, H4c
chr10_+_71444655 0.17 ENST00000434931.2
RP11-242G20.1
Uncharacterized protein
chr22_-_31536480 0.17 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr6_+_46761118 0.17 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr17_+_6347729 0.16 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr22_-_39637135 0.16 ENST00000440375.1
PDGFB
platelet-derived growth factor beta polypeptide
chr7_+_144015218 0.16 ENST00000408951.1
OR2A1
olfactory receptor, family 2, subfamily A, member 1
chr19_+_35168567 0.16 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302
zinc finger protein 302
chr2_-_204398141 0.16 ENST00000428637.1
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr17_-_42994283 0.16 ENST00000593179.1
GFAP
glial fibrillary acidic protein
chr19_-_10613862 0.16 ENST00000592055.1
KEAP1
kelch-like ECH-associated protein 1
chr22_-_31503490 0.16 ENST00000400299.2
SELM
Selenoprotein M
chr11_-_104480019 0.16 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr8_-_27468717 0.15 ENST00000520796.1
ENST00000520491.1
CLU
clusterin
chr3_-_93692781 0.15 ENST00000394236.3
PROS1
protein S (alpha)
chr9_+_136287444 0.15 ENST00000355699.2
ENST00000356589.2
ENST00000371911.3
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr12_-_48276710 0.15 ENST00000550314.1
VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
chr10_-_90751038 0.15 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr12_+_7022909 0.15 ENST00000537688.1
ENO2
enolase 2 (gamma, neuronal)
chr8_-_27469196 0.15 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr12_-_11175219 0.15 ENST00000390673.2
TAS2R19
taste receptor, type 2, member 19
chr15_-_79576156 0.15 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
RP11-17L5.4
RP11-17L5.4
chr19_-_40324767 0.15 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr17_+_36858694 0.14 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr3_+_45430105 0.14 ENST00000430399.1
LARS2
leucyl-tRNA synthetase 2, mitochondrial
chr4_-_155511887 0.14 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr19_-_11688951 0.14 ENST00000589792.1
ACP5
acid phosphatase 5, tartrate resistant
chr7_-_26578407 0.14 ENST00000242109.3
KIAA0087
KIAA0087
chr17_+_2264983 0.14 ENST00000574650.1
SGSM2
small G protein signaling modulator 2
chr7_+_106415457 0.13 ENST00000490162.2
ENST00000470135.1
RP5-884M6.1
RP5-884M6.1
chr12_-_7245018 0.13 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr12_-_120687948 0.13 ENST00000458477.2
PXN
paxillin
chr1_-_147632428 0.13 ENST00000599640.1
BX842679.1
Uncharacterized protein FLJ46360
chr8_-_37351424 0.13 ENST00000522718.1
RP11-150O12.1
RP11-150O12.1
chr19_-_58864848 0.13 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr1_-_153521597 0.13 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chrX_-_153210107 0.13 ENST00000369997.3
ENST00000393700.3
ENST00000412763.1
RENBP
renin binding protein
chr6_+_131571535 0.13 ENST00000474850.2
AKAP7
A kinase (PRKA) anchor protein 7
chr16_-_67260901 0.13 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
LRRC29
AC040160.1
leucine rich repeat containing 29
Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr12_-_49245916 0.13 ENST00000552512.1
ENST00000551468.1
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr15_-_41120896 0.12 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr15_+_57998821 0.12 ENST00000299638.3
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr11_+_844067 0.12 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4
tetraspanin 4
chr13_-_30160925 0.12 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr8_-_27468945 0.12 ENST00000405140.3
CLU
clusterin
chr18_+_66382428 0.12 ENST00000578970.1
ENST00000582371.1
ENST00000584775.1
CCDC102B
coiled-coil domain containing 102B
chr14_-_20881579 0.12 ENST00000556935.1
ENST00000262715.5
ENST00000556549.1
TEP1
telomerase-associated protein 1
chr6_-_36355513 0.12 ENST00000340181.4
ENST00000373737.4
ETV7
ets variant 7
chr11_+_75479850 0.12 ENST00000376262.3
ENST00000604733.1
DGAT2
diacylglycerol O-acyltransferase 2
chr6_-_127840048 0.12 ENST00000467753.1
SOGA3
SOGA family member 3
chr20_-_25320367 0.12 ENST00000450393.1
ENST00000491682.1
ABHD12
abhydrolase domain containing 12
chr1_-_151138422 0.12 ENST00000440902.2
LYSMD1
LysM, putative peptidoglycan-binding, domain containing 1
chr3_-_4793274 0.12 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr1_-_11107280 0.11 ENST00000400897.3
ENST00000400898.3
MASP2
mannan-binding lectin serine peptidase 2
chr11_-_68611721 0.11 ENST00000561996.1
CPT1A
carnitine palmitoyltransferase 1A (liver)
chrX_-_115594160 0.11 ENST00000371894.4
CXorf61
cancer/testis antigen 83
chr14_-_25479811 0.11 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr16_-_3030407 0.11 ENST00000431515.2
ENST00000574385.1
ENST00000576268.1
ENST00000574730.1
ENST00000575632.1
ENST00000573944.1
ENST00000262300.8
PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
chr8_-_27468842 0.11 ENST00000523500.1
CLU
clusterin
chr15_+_57998923 0.11 ENST00000380557.4
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr12_-_42877726 0.11 ENST00000548696.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr8_-_37351344 0.11 ENST00000520422.1
RP11-150O12.1
RP11-150O12.1
chr19_+_44764031 0.11 ENST00000592581.1
ENST00000590668.1
ENST00000588489.1
ENST00000391958.2
ZNF233
zinc finger protein 233
chr12_+_12224331 0.11 ENST00000396367.1
ENST00000266434.4
ENST00000396369.1
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr8_+_82644669 0.11 ENST00000297265.4
CHMP4C
charged multivesicular body protein 4C
chr15_-_23891175 0.11 ENST00000532292.1
MAGEL2
MAGE-like 2
chr19_-_10613361 0.10 ENST00000591039.1
ENST00000591419.1
KEAP1
kelch-like ECH-associated protein 1
chr19_+_56905024 0.10 ENST00000591172.1
ENST00000589888.1
ENST00000587979.1
ENST00000585659.1
ENST00000593109.1
ZNF582-AS1
ZNF582 antisense RNA 1 (head to head)
chr19_+_13228917 0.10 ENST00000586171.1
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr11_+_73498973 0.10 ENST00000537007.1
MRPL48
mitochondrial ribosomal protein L48
chr17_-_39459103 0.10 ENST00000391353.1
KRTAP29-1
keratin associated protein 29-1
chr2_+_220306238 0.10 ENST00000435853.1
SPEG
SPEG complex locus
chr8_-_27469383 0.10 ENST00000519742.1
CLU
clusterin
chr4_-_185694872 0.10 ENST00000505492.1
ACSL1
acyl-CoA synthetase long-chain family member 1
chr19_+_44331555 0.10 ENST00000590950.1
ZNF283
zinc finger protein 283
chr1_+_153631130 0.10 ENST00000368685.5
SNAPIN
SNAP-associated protein
chr11_+_111412271 0.10 ENST00000528102.1
LAYN
layilin
chr5_-_39274617 0.10 ENST00000510188.1
FYB
FYN binding protein
chr5_-_38845812 0.10 ENST00000513480.1
ENST00000512519.1
CTD-2127H9.1
CTD-2127H9.1
chr6_+_41604620 0.10 ENST00000432027.1
MDFI
MyoD family inhibitor
chr4_-_76957214 0.10 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr16_-_21663950 0.10 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr14_-_100841794 0.10 ENST00000556295.1
ENST00000554820.1
WARS
tryptophanyl-tRNA synthetase
chr12_-_42878101 0.10 ENST00000552108.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr2_-_70189397 0.09 ENST00000320256.4
ASPRV1
aspartic peptidase, retroviral-like 1
chr17_-_19265855 0.09 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9D1
B9 protein domain 1
chr6_-_28973037 0.09 ENST00000377179.3
ZNF311
zinc finger protein 311
chr1_+_155006300 0.09 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1
DC-STAMP domain containing 1
chr17_+_74729060 0.09 ENST00000587459.1
RP11-318A15.7
Uncharacterized protein
chr7_-_33842742 0.09 ENST00000420185.1
ENST00000440034.1
RP11-89N17.4
RP11-89N17.4
chr19_+_17326521 0.09 ENST00000593597.1
USE1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr1_+_229440129 0.09 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr16_+_70332956 0.09 ENST00000288071.6
ENST00000393657.2
ENST00000355992.3
ENST00000567706.1
DDX19B
RP11-529K1.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
Uncharacterized protein
chr14_+_76452090 0.09 ENST00000314067.6
ENST00000238628.6
ENST00000556742.1
IFT43
intraflagellar transport 43 homolog (Chlamydomonas)
chr5_-_119669160 0.09 ENST00000514240.1
CTC-552D5.1
CTC-552D5.1
chr14_-_45431091 0.09 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr5_+_61708488 0.09 ENST00000505902.1
IPO11
importin 11
chr19_+_18530184 0.09 ENST00000601357.2
SSBP4
single stranded DNA binding protein 4
chr6_+_106535455 0.09 ENST00000424894.1
PRDM1
PR domain containing 1, with ZNF domain
chr18_-_67629015 0.08 ENST00000579496.1
CD226
CD226 molecule
chr2_-_190044480 0.08 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr6_+_44194762 0.08 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr3_+_187871060 0.08 ENST00000448637.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr19_+_57106647 0.08 ENST00000328070.6
ZNF71
zinc finger protein 71
chr11_-_111782484 0.08 ENST00000533971.1
CRYAB
crystallin, alpha B
chr3_+_46283863 0.08 ENST00000545097.1
ENST00000541018.1
CCR3
chemokine (C-C motif) receptor 3
chr12_-_11184006 0.08 ENST00000390675.2
TAS2R31
taste receptor, type 2, member 31
chr19_-_7167989 0.08 ENST00000600492.1
INSR
insulin receptor
chr16_-_29874211 0.08 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr17_+_48624450 0.08 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
SPATA20
spermatogenesis associated 20
chr20_+_54987305 0.08 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr14_-_100841670 0.08 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
WARS
tryptophanyl-tRNA synthetase
chr11_-_111649074 0.08 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr3_+_77088989 0.08 ENST00000461745.1
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr6_+_292253 0.08 ENST00000603453.1
ENST00000605315.1
ENST00000603881.1
DUSP22
dual specificity phosphatase 22
chr1_+_244227632 0.08 ENST00000598000.1
AL590483.1
Uncharacterized protein; cDNA FLJ42623 fis, clone BRACE3015894
chr19_+_47835404 0.08 ENST00000595464.1
C5AR2
complement component 5a receptor 2
chr22_+_45725524 0.08 ENST00000405548.3
FAM118A
family with sequence similarity 118, member A
chr14_-_81408063 0.08 ENST00000557411.1
CEP128
centrosomal protein 128kDa
chr19_+_49128209 0.08 ENST00000599748.1
ENST00000443164.1
ENST00000599029.1
SPHK2
sphingosine kinase 2
chr17_-_26697304 0.08 ENST00000536498.1
VTN
vitronectin
chr11_+_66025091 0.08 ENST00000526758.1
ENST00000440228.2
KLC2
kinesin light chain 2
chr1_+_153004800 0.08 ENST00000392661.3
SPRR1B
small proline-rich protein 1B
chr19_-_44809121 0.07 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
ZNF235
zinc finger protein 235
chrX_+_107288280 0.07 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr18_-_53253323 0.07 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr14_+_32963433 0.07 ENST00000554410.1
AKAP6
A kinase (PRKA) anchor protein 6
chr1_-_144995074 0.07 ENST00000534536.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr2_+_17935383 0.07 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1
GEN1 Holliday junction 5' flap endonuclease
chr6_+_31730773 0.07 ENST00000415669.2
ENST00000425424.1
SAPCD1
suppressor APC domain containing 1
chr6_+_108977520 0.07 ENST00000540898.1
FOXO3
forkhead box O3
chr3_+_62304648 0.07 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chr7_+_76026832 0.07 ENST00000336517.4
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr12_-_58165870 0.07 ENST00000257848.7
METTL1
methyltransferase like 1
chr1_-_151138323 0.07 ENST00000368908.5
LYSMD1
LysM, putative peptidoglycan-binding, domain containing 1
chr1_+_165864800 0.07 ENST00000469256.2
UCK2
uridine-cytidine kinase 2
chr6_-_39197226 0.07 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chrX_+_129473859 0.07 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr2_+_27760247 0.07 ENST00000447166.1
AC109829.1
Uncharacterized protein
chr16_-_66519747 0.07 ENST00000544589.1
AC132186.1
CDNA FLJ27243 fis, clone SYN08134; Uncharacterized protein
chr7_-_100881041 0.07 ENST00000412417.1
ENST00000414035.1
CLDN15
claudin 15
chr1_+_114472992 0.07 ENST00000514621.1
HIPK1
homeodomain interacting protein kinase 1
chr2_-_28113217 0.07 ENST00000444339.2
RBKS
ribokinase
chr11_-_6462210 0.07 ENST00000265983.3
HPX
hemopexin
chr1_+_182584314 0.07 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr15_+_84322827 0.07 ENST00000286744.5
ENST00000567476.1
ADAMTSL3
ADAMTS-like 3
chr11_+_46740730 0.07 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2
coagulation factor II (thrombin)
chr11_-_9781068 0.07 ENST00000500698.1
RP11-540A21.2
RP11-540A21.2
chr19_+_10196981 0.07 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr11_+_7618413 0.07 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_-_44405623 0.07 ENST00000591815.1
RP11-15A1.3
RP11-15A1.3
chrX_-_62571187 0.07 ENST00000335144.3
SPIN4
spindlin family, member 4
chr6_+_63921399 0.07 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr19_+_44331444 0.07 ENST00000324461.7
ZNF283
zinc finger protein 283
chr19_+_44598492 0.06 ENST00000589680.1
ZNF224
zinc finger protein 224
chr4_+_86396265 0.06 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr11_-_62323702 0.06 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr16_+_67563250 0.06 ENST00000566907.1
FAM65A
family with sequence similarity 65, member A
chr5_+_140501581 0.06 ENST00000194152.1
PCDHB4
protocadherin beta 4
chr1_+_15668240 0.06 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr1_+_6511651 0.06 ENST00000434576.1
ESPN
espin
chr2_+_101591314 0.06 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr17_-_38210644 0.06 ENST00000394128.2
ENST00000394127.2
ENST00000356271.3
ENST00000535071.2
ENST00000580885.1
ENST00000543759.2
ENST00000537674.2
ENST00000580517.1
ENST00000578161.1
MED24
mediator complex subunit 24
chr16_-_89785777 0.06 ENST00000561976.1
VPS9D1
VPS9 domain containing 1
chrX_-_2882296 0.06 ENST00000438544.1
ENST00000381134.3
ENST00000545496.1
ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr11_+_65657875 0.06 ENST00000312579.2
CCDC85B
coiled-coil domain containing 85B
chr16_+_67261008 0.06 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
TMEM208
transmembrane protein 208
chr9_+_125796806 0.06 ENST00000373642.1
GPR21
G protein-coupled receptor 21
chr17_+_76311791 0.06 ENST00000586321.1
AC061992.2
AC061992.2
chr3_-_148939835 0.06 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr19_-_1155118 0.06 ENST00000590998.1
SBNO2
strawberry notch homolog 2 (Drosophila)
chr2_-_197675000 0.06 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr1_-_161207986 0.06 ENST00000506209.1
ENST00000367980.2
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr7_-_27135591 0.06 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr19_+_18530146 0.06 ENST00000348495.6
ENST00000270061.7
SSBP4
single stranded DNA binding protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT1_STAT3_BCL6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.2 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.5 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.3 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.1 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.1 0.2 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.1 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.1 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0090677 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.1 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.1 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.4 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:2000360 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) negative regulation of fertilization(GO:0060467) acrosomal vesicle exocytosis(GO:0060478) regulation of binding of sperm to zona pellucida(GO:2000359) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.0 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.2 GO:0035864 response to potassium ion(GO:0035864)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.0 GO:0032827 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.0 GO:1902024 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.0 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.1 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.0 GO:1902868 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.0 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.0 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.0 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.2 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0001847 opsonin receptor activity(GO:0001847)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.0 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.1 GO:0015227 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.0 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.0 GO:0050135 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels