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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for STAT5A

Z-value: 0.86

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Transcription factors associated with STAT5A

Gene Symbol Gene ID Gene Info
STAT5A
ENSG00000126561.12 signal transducer and activator of transcription 5A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT5Ahg19_v2_chr17_+_40440481_40440561-0.157.7e-01Click!

Activity profile of STAT5A motif

Sorted Z-values of STAT5A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_133656995 0.64 ENST00000356456.5
ZNF140
zinc finger protein 140
chr20_+_58571419 0.59 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
CDH26
cadherin 26
chr13_+_20268547 0.51 ENST00000601204.1
AL354808.2
AL354808.2
chr8_-_123139423 0.43 ENST00000523792.1
RP11-398G24.2
RP11-398G24.2
chr3_-_165555200 0.41 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr3_-_4927447 0.38 ENST00000449914.1
AC018816.3
Uncharacterized protein
chr16_+_70207686 0.38 ENST00000541793.2
ENST00000314151.8
ENST00000565806.1
ENST00000569347.2
ENST00000536907.2
CLEC18C
C-type lectin domain family 18, member C
chr10_+_6625605 0.38 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr2_+_181988620 0.38 ENST00000428474.1
ENST00000424655.1
AC104820.2
AC104820.2
chr11_-_111320706 0.38 ENST00000531398.1
POU2AF1
POU class 2 associating factor 1
chr7_+_30589829 0.37 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr7_-_139727118 0.36 ENST00000484111.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr15_+_63414760 0.35 ENST00000557972.1
LACTB
lactamase, beta
chrX_+_106045891 0.35 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1D8B
TBC1 domain family, member 8B (with GRAM domain)
chr12_+_66696322 0.35 ENST00000247815.4
HELB
helicase (DNA) B
chr4_+_130017268 0.34 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chr12_+_21207503 0.31 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr2_-_75796837 0.31 ENST00000233712.1
EVA1A
eva-1 homolog A (C. elegans)
chr3_-_160116995 0.30 ENST00000465537.1
ENST00000486856.1
ENST00000468218.1
ENST00000478370.1
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr11_-_71750865 0.30 ENST00000544129.1
NUMA1
nuclear mitotic apparatus protein 1
chr10_-_33625154 0.30 ENST00000265371.4
NRP1
neuropilin 1
chr12_-_15082050 0.29 ENST00000540097.1
ERP27
endoplasmic reticulum protein 27
chr1_-_115632035 0.29 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2
tetraspanin 2
chr11_-_114271139 0.27 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr6_+_32605134 0.27 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr3_-_160117301 0.27 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr1_-_226065330 0.27 ENST00000436966.1
TMEM63A
transmembrane protein 63A
chr7_+_142829162 0.27 ENST00000291009.3
PIP
prolactin-induced protein
chr2_-_98972468 0.26 ENST00000454230.1
AC092675.3
Uncharacterized protein
chr1_-_55230165 0.25 ENST00000371279.3
PARS2
prolyl-tRNA synthetase 2, mitochondrial (putative)
chr14_-_51135005 0.25 ENST00000556735.1
SAV1
salvador homolog 1 (Drosophila)
chr6_+_32605195 0.24 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr8_+_101349823 0.24 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr6_-_56716686 0.24 ENST00000520645.1
DST
dystonin
chr2_+_149894968 0.24 ENST00000409642.3
LYPD6B
LY6/PLAUR domain containing 6B
chr10_+_90484301 0.24 ENST00000404190.1
LIPK
lipase, family member K
chr3_-_139108463 0.24 ENST00000512242.1
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr17_+_61151306 0.23 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr3_-_160117035 0.23 ENST00000489004.1
ENST00000496589.1
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr2_-_55237484 0.23 ENST00000394609.2
RTN4
reticulon 4
chr11_-_111649074 0.23 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr12_-_8815299 0.22 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr2_+_149895207 0.22 ENST00000409876.1
LYPD6B
LY6/PLAUR domain containing 6B
chr9_-_89562104 0.21 ENST00000298743.7
GAS1
growth arrest-specific 1
chr18_-_64271316 0.21 ENST00000540086.1
ENST00000580157.1
CDH19
cadherin 19, type 2
chr17_-_72968837 0.21 ENST00000581676.1
HID1
HID1 domain containing
chr2_-_165630264 0.21 ENST00000452626.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr4_+_38511367 0.21 ENST00000507056.1
RP11-213G21.1
RP11-213G21.1
chr4_+_108815402 0.21 ENST00000503385.1
SGMS2
sphingomyelin synthase 2
chr1_+_158975744 0.21 ENST00000426592.2
IFI16
interferon, gamma-inducible protein 16
chr8_+_109455830 0.20 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr4_+_25378912 0.20 ENST00000510092.1
ENST00000505991.1
ANAPC4
anaphase promoting complex subunit 4
chr20_+_33464368 0.20 ENST00000484354.1
ENST00000493805.2
ENST00000473172.1
ACSS2
acyl-CoA synthetase short-chain family member 2
chr3_-_78719376 0.20 ENST00000495961.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr13_-_51101468 0.19 ENST00000428276.1
RP11-175B12.2
RP11-175B12.2
chr5_+_127039075 0.19 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr2_+_37423618 0.19 ENST00000402297.1
ENST00000397064.2
ENST00000406711.1
ENST00000392061.2
ENST00000397226.2
AC007390.5
CEBPZ antisense RNA 1
chr17_-_34207295 0.19 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr19_-_44809121 0.19 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
ZNF235
zinc finger protein 235
chr19_-_19729725 0.19 ENST00000251203.9
PBX4
pre-B-cell leukemia homeobox 4
chr1_+_59775752 0.19 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr14_-_24977457 0.18 ENST00000250378.3
ENST00000206446.4
CMA1
chymase 1, mast cell
chr19_-_37407172 0.18 ENST00000391711.3
ZNF829
zinc finger protein 829
chr20_+_58251716 0.18 ENST00000355648.4
PHACTR3
phosphatase and actin regulator 3
chr12_+_79357815 0.18 ENST00000547046.1
SYT1
synaptotagmin I
chr17_+_67498396 0.18 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr12_+_133657461 0.18 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
ZNF140
zinc finger protein 140
chr19_-_44405941 0.17 ENST00000587128.1
RP11-15A1.3
RP11-15A1.3
chr12_+_117013656 0.17 ENST00000556529.1
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr17_-_60005365 0.17 ENST00000444766.3
INTS2
integrator complex subunit 2
chr2_-_203735586 0.17 ENST00000454326.1
ENST00000432273.1
ENST00000450143.1
ENST00000411681.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr11_-_82997371 0.17 ENST00000525503.1
CCDC90B
coiled-coil domain containing 90B
chr12_+_44152740 0.17 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
IRAK4
interleukin-1 receptor-associated kinase 4
chr13_-_99404875 0.17 ENST00000376503.5
SLC15A1
solute carrier family 15 (oligopeptide transporter), member 1
chr1_-_245026388 0.17 ENST00000440865.1
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr1_-_197115818 0.17 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr3_+_142342228 0.17 ENST00000337777.3
PLS1
plastin 1
chr8_-_33330595 0.17 ENST00000524021.1
ENST00000335589.3
FUT10
fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
chr7_-_48019101 0.16 ENST00000432627.1
ENST00000258774.5
ENST00000432325.1
ENST00000446009.1
HUS1
HUS1 checkpoint homolog (S. pombe)
chr2_+_163200848 0.16 ENST00000233612.4
GCA
grancalcin, EF-hand calcium binding protein
chr18_+_61575200 0.16 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr1_+_38478432 0.16 ENST00000537711.1
UTP11L
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr10_-_5652705 0.16 ENST00000425246.1
RP11-336A10.5
RP11-336A10.5
chr20_+_5987890 0.16 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr6_+_116892641 0.16 ENST00000487832.2
ENST00000518117.1
RWDD1
RWD domain containing 1
chr18_-_66382289 0.16 ENST00000443099.2
ENST00000562706.1
ENST00000544714.2
TMX3
thioredoxin-related transmembrane protein 3
chr18_-_68004529 0.16 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr14_-_74025625 0.16 ENST00000553558.1
ENST00000563329.1
ENST00000334988.2
ENST00000560393.1
HEATR4
HEAT repeat containing 4
chr19_+_37960240 0.16 ENST00000388801.3
ZNF570
zinc finger protein 570
chr4_-_146019693 0.16 ENST00000514390.1
ANAPC10
anaphase promoting complex subunit 10
chr10_-_6622201 0.16 ENST00000539722.1
ENST00000397176.2
PRKCQ
protein kinase C, theta
chr19_+_57106624 0.16 ENST00000599599.1
ZNF71
zinc finger protein 71
chr9_+_86237963 0.15 ENST00000277124.8
IDNK
idnK, gluconokinase homolog (E. coli)
chr12_+_69080734 0.15 ENST00000378905.2
NUP107
nucleoporin 107kDa
chr9_+_114287433 0.15 ENST00000358151.4
ENST00000355824.3
ENST00000374374.3
ENST00000309235.5
ZNF483
zinc finger protein 483
chr7_+_99425633 0.15 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
CYP3A43
cytochrome P450, family 3, subfamily A, polypeptide 43
chr2_+_112813134 0.15 ENST00000452614.1
TMEM87B
transmembrane protein 87B
chr14_+_39583427 0.15 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
GEMIN2
gem (nuclear organelle) associated protein 2
chr19_-_44952635 0.15 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
ZNF229
zinc finger protein 229
chr1_-_48937821 0.15 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr6_+_122793058 0.15 ENST00000392491.2
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr14_-_36983034 0.15 ENST00000518529.2
SFTA3
surfactant associated 3
chr14_+_90422239 0.15 ENST00000393452.3
ENST00000554180.1
ENST00000393454.2
ENST00000553617.1
ENST00000335725.4
ENST00000357382.3
ENST00000556867.1
ENST00000553527.1
TDP1
tyrosyl-DNA phosphodiesterase 1
chr20_-_52612705 0.14 ENST00000434986.2
BCAS1
breast carcinoma amplified sequence 1
chr1_-_48937682 0.14 ENST00000371843.3
SPATA6
spermatogenesis associated 6
chr17_+_76356516 0.14 ENST00000592569.1
RP11-806H10.4
RP11-806H10.4
chr7_-_42971759 0.14 ENST00000538645.1
ENST00000445517.1
ENST00000223321.4
PSMA2
proteasome (prosome, macropain) subunit, alpha type, 2
chr18_+_61144160 0.14 ENST00000489441.1
ENST00000424602.1
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr11_+_114271367 0.14 ENST00000544582.1
ENST00000545678.1
RBM7
RNA binding motif protein 7
chr3_-_171489085 0.14 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr19_+_52430688 0.14 ENST00000391794.4
ENST00000599683.1
ENST00000600853.1
ZNF613
zinc finger protein 613
chr2_-_68290106 0.14 ENST00000407324.1
ENST00000355848.3
ENST00000409302.1
ENST00000410067.3
C1D
C1D nuclear receptor corepressor
chr11_+_114271251 0.14 ENST00000375490.5
RBM7
RNA binding motif protein 7
chr17_+_32582293 0.14 ENST00000580907.1
ENST00000225831.4
CCL2
chemokine (C-C motif) ligand 2
chr2_+_238969728 0.14 ENST00000416757.1
SCLY
selenocysteine lyase
chr14_+_45605127 0.14 ENST00000556036.1
ENST00000267430.5
FANCM
Fanconi anemia, complementation group M
chr3_+_160117418 0.14 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4
structural maintenance of chromosomes 4
chr14_-_21270561 0.14 ENST00000412779.2
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr6_+_76330355 0.14 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr19_+_44669221 0.14 ENST00000590578.1
ENST00000589160.1
ENST00000337433.5
ENST00000586286.1
ENST00000585560.1
ENST00000586914.1
ENST00000588883.1
ENST00000413984.2
ENST00000588742.1
ENST00000300823.6
ENST00000585678.1
ENST00000586203.1
ENST00000590467.1
ENST00000588795.1
ENST00000588127.1
ZNF226
zinc finger protein 226
chr17_-_60005329 0.14 ENST00000251334.6
INTS2
integrator complex subunit 2
chr1_-_115301235 0.14 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr14_+_22591276 0.14 ENST00000390455.3
TRAV26-1
T cell receptor alpha variable 26-1
chr1_-_182558374 0.14 ENST00000367559.3
ENST00000539397.1
RNASEL
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr14_-_94759595 0.14 ENST00000261994.4
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr7_-_130597935 0.13 ENST00000447307.1
ENST00000418546.1
MIR29B1
microRNA 29a
chr19_+_12203069 0.13 ENST00000430298.2
ENST00000339302.4
ZNF788
ZNF788
zinc finger family member 788
Zinc finger protein 788
chr5_-_42812143 0.13 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr19_-_45004556 0.13 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
ZNF180
zinc finger protein 180
chrX_-_3264682 0.13 ENST00000217939.6
MXRA5
matrix-remodelling associated 5
chr16_+_16481306 0.13 ENST00000422673.2
NPIPA7
nuclear pore complex interacting protein family, member A7
chr22_+_21128167 0.13 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr17_+_6347761 0.13 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A
family with sequence similarity 64, member A
chr21_+_34602377 0.13 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr19_+_58193337 0.13 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
ZNF551
zinc finger protein 551
chr17_+_48823975 0.13 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr8_-_27469383 0.13 ENST00000519742.1
CLU
clusterin
chr8_+_67104940 0.13 ENST00000517689.1
LINC00967
long intergenic non-protein coding RNA 967
chr4_+_86396321 0.13 ENST00000503995.1
ARHGAP24
Rho GTPase activating protein 24
chr17_+_6544328 0.13 ENST00000570330.1
TXNDC17
thioredoxin domain containing 17
chr12_-_21910775 0.13 ENST00000539782.1
LDHB
lactate dehydrogenase B
chr1_-_94344686 0.13 ENST00000528680.1
DNTTIP2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr14_-_100841930 0.13 ENST00000555031.1
ENST00000553395.1
ENST00000553545.1
ENST00000344102.5
ENST00000556338.1
ENST00000392882.2
ENST00000553934.1
WARS
tryptophanyl-tRNA synthetase
chr5_+_112312454 0.13 ENST00000543319.1
DCP2
decapping mRNA 2
chr2_+_196522032 0.13 ENST00000418005.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr20_+_19738792 0.13 ENST00000412571.1
RP1-122P22.2
RP1-122P22.2
chr12_+_28605426 0.13 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chrX_-_20134713 0.13 ENST00000452324.3
MAP7D2
MAP7 domain containing 2
chr11_+_73358594 0.13 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr11_+_36589547 0.13 ENST00000299440.5
RAG1
recombination activating gene 1
chr8_-_102803163 0.13 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr3_-_93692681 0.13 ENST00000348974.4
PROS1
protein S (alpha)
chr19_+_44617511 0.13 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
ZNF225
zinc finger protein 225
chr19_+_8274512 0.13 ENST00000560412.1
CERS4
ceramide synthase 4
chr9_-_94877658 0.13 ENST00000262554.2
ENST00000337841.4
SPTLC1
serine palmitoyltransferase, long chain base subunit 1
chr14_+_63671105 0.13 ENST00000316754.3
RHOJ
ras homolog family member J
chr1_-_144994840 0.12 ENST00000369351.3
ENST00000369349.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_+_158969752 0.12 ENST00000566111.1
IFI16
interferon, gamma-inducible protein 16
chr5_+_173763250 0.12 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
RP11-267A15.1
chr3_+_141144963 0.12 ENST00000510726.1
ZBTB38
zinc finger and BTB domain containing 38
chr11_+_114271314 0.12 ENST00000541475.1
RBM7
RNA binding motif protein 7
chr1_-_144994909 0.12 ENST00000369347.4
ENST00000369354.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr19_+_37407351 0.12 ENST00000455427.2
ENST00000587857.1
ZNF568
zinc finger protein 568
chr2_+_112812778 0.12 ENST00000283206.4
TMEM87B
transmembrane protein 87B
chr4_-_38807199 0.12 ENST00000508364.1
TLR1
toll-like receptor 1
chr8_-_27468717 0.12 ENST00000520796.1
ENST00000520491.1
CLU
clusterin
chr8_-_103884640 0.12 ENST00000520402.1
AZIN1
antizyme inhibitor 1
chr3_+_122296443 0.12 ENST00000464300.2
PARP15
poly (ADP-ribose) polymerase family, member 15
chr16_+_30996502 0.12 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
HSD3B7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr9_+_86238016 0.12 ENST00000530832.1
ENST00000405990.3
ENST00000376417.4
ENST00000376419.4
IDNK
idnK, gluconokinase homolog (E. coli)
chr11_-_104893863 0.12 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
CASP5
caspase 5, apoptosis-related cysteine peptidase
chr4_-_74486109 0.12 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr11_+_121163466 0.12 ENST00000527762.1
ENST00000534230.1
ENST00000392789.2
SC5D
sterol-C5-desaturase
chr6_+_123038689 0.12 ENST00000354275.2
ENST00000368446.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr6_-_5004241 0.12 ENST00000319533.5
ENST00000380051.2
RPP40
ribonuclease P/MRP 40kDa subunit
chr12_+_10658489 0.12 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr15_-_65282274 0.12 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr12_-_62997214 0.12 ENST00000408887.2
C12orf61
chromosome 12 open reading frame 61
chr11_+_114270752 0.12 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr14_-_92333873 0.12 ENST00000435962.2
TC2N
tandem C2 domains, nuclear
chr7_+_5938351 0.12 ENST00000325974.6
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr15_-_65282232 0.12 ENST00000416889.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr19_+_7953417 0.12 ENST00000600345.1
ENST00000598224.1
LRRC8E
leucine rich repeat containing 8 family, member E
chr9_-_25678856 0.11 ENST00000358022.3
TUSC1
tumor suppressor candidate 1
chr10_-_116444371 0.11 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr9_-_75653627 0.11 ENST00000446946.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chrX_-_41449204 0.11 ENST00000378179.3
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr15_+_50474385 0.11 ENST00000267842.5
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr11_-_85430356 0.11 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr4_+_142558078 0.11 ENST00000529613.1
IL15
interleukin 15
chr19_+_44507091 0.11 ENST00000429154.2
ENST00000585632.1
ZNF230
zinc finger protein 230
chr14_-_58893832 0.11 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr6_-_86303523 0.11 ENST00000513865.1
ENST00000369627.2
ENST00000514419.1
ENST00000509338.1
ENST00000314673.3
ENST00000346348.3
SNX14
sorting nexin 14
chr4_-_156298087 0.11 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr2_-_10830093 0.11 ENST00000381685.5
ENST00000345985.3
ENST00000542668.1
ENST00000538384.1
NOL10
nucleolar protein 10
chr11_+_58912240 0.11 ENST00000527629.1
ENST00000361723.3
ENST00000531408.1
FAM111A
family with sequence similarity 111, member A
chr3_-_160823158 0.11 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr11_+_19138670 0.11 ENST00000446113.2
ENST00000399351.3
ZDHHC13
zinc finger, DHHC-type containing 13
chr17_-_39459103 0.11 ENST00000391353.1
KRTAP29-1
keratin associated protein 29-1
chr19_-_41220540 0.11 ENST00000594490.1
ADCK4
aarF domain containing kinase 4

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT5A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.2 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1 0.3 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501)
0.1 0.2 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.2 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.3 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) sensory neuron axon guidance(GO:0097374) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.4 GO:0009820 alkaloid metabolic process(GO:0009820)
0.1 0.2 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.4 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.3 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.3 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0035712 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.2 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.3 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.1 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.2 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.1 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961) calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:1903060 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0051300 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.1 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.0 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 0.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0008355 olfactory learning(GO:0008355)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0070943 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944) neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.0 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.0 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.0 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.0 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.0 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.0 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.0 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.2 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.6 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0070701 mucus layer(GO:0070701)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.0 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.0 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 0.4 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.4 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.3 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.2 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 0.2 GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908)
0.1 0.2 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.0 0.5 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.4 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.0 0.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0000035 acyl binding(GO:0000035)
0.0 0.0 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.0 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.2 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis