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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBP

Z-value: 2.42

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Transcription factors associated with TBP

Gene Symbol Gene ID Gene Info
TBP
ENSG00000112592.8 TATA-box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBPhg19_v2_chr6_+_170863421_170863484-0.805.6e-02Click!

Activity profile of TBP motif

Sorted Z-values of TBP motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153013588 5.40 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr1_-_153044083 4.27 ENST00000341611.2
SPRR2B
small proline-rich protein 2B
chr11_-_18270182 4.09 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr11_+_18287721 3.90 ENST00000356524.4
SAA1
serum amyloid A1
chr11_+_18287801 3.89 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr19_+_10381769 3.60 ENST00000423829.2
ENST00000588645.1
ICAM1
intercellular adhesion molecule 1
chr4_-_74904398 3.04 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr4_+_74606223 2.79 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr1_-_153363452 2.69 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr1_+_153330322 2.63 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr19_-_6720686 2.54 ENST00000245907.6
C3
complement component 3
chr15_+_45722727 2.45 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr1_+_37940153 2.32 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr6_-_26250835 2.09 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr9_-_35658007 2.05 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr6_-_133035185 2.04 ENST00000367928.4
VNN1
vanin 1
chr7_-_41742697 2.04 ENST00000242208.4
INHBA
inhibin, beta A
chr6_+_26156551 1.96 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr4_+_74735102 1.94 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr1_+_152881014 1.81 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr6_+_27861190 1.73 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr1_+_153003671 1.63 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr17_+_77021702 1.63 ENST00000392445.2
ENST00000354124.3
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr11_-_615570 1.63 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr11_-_1619524 1.59 ENST00000412090.1
KRTAP5-2
keratin associated protein 5-2
chr17_-_38859996 1.59 ENST00000264651.2
KRT24
keratin 24
chr4_+_74702214 1.57 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr12_-_52845910 1.51 ENST00000252252.3
KRT6B
keratin 6B
chr6_-_26108355 1.47 ENST00000338379.4
HIST1H1T
histone cluster 1, H1t
chr3_+_101546827 1.47 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr11_-_102826434 1.44 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr6_-_27100529 1.42 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ
histone cluster 1, H2bj
chr5_+_53686658 1.34 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr16_+_2880369 1.21 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr18_+_68002675 1.18 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr2_+_40973618 1.14 ENST00000420187.1
AC007317.1
AC007317.1
chr9_+_130911723 1.11 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr10_+_91087651 1.10 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr19_-_10946949 1.05 ENST00000214869.2
ENST00000591695.1
TMED1
transmembrane emp24 protein transport domain containing 1
chr13_-_43566301 1.03 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chr2_+_113763031 1.02 ENST00000259211.6
IL36A
interleukin 36, alpha
chr2_+_90248739 1.01 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr17_-_79792909 0.97 ENST00000330261.4
ENST00000570394.1
PPP1R27
protein phosphatase 1, regulatory subunit 27
chr16_+_82068830 0.96 ENST00000199936.4
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr19_-_12912688 0.95 ENST00000435703.1
PRDX2
peroxiredoxin 2
chr6_-_27806117 0.94 ENST00000330180.2
HIST1H2AK
histone cluster 1, H2ak
chr20_+_31823792 0.94 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPIFA1
BPI fold containing family A, member 1
chr1_+_149822620 0.92 ENST00000369159.2
HIST2H2AA4
histone cluster 2, H2aa4
chr6_+_26104104 0.91 ENST00000377803.2
HIST1H4C
histone cluster 1, H4c
chr11_-_102651343 0.90 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr11_-_62432641 0.90 ENST00000528405.1
ENST00000524958.1
ENST00000525675.1
RP11-831H9.11
C11orf48
Uncharacterized protein
chromosome 11 open reading frame 48
chr19_+_46732988 0.89 ENST00000437936.1
IGFL1
IGF-like family member 1
chr9_+_140135665 0.86 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr10_+_91152303 0.84 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr12_-_49582593 0.83 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr6_-_26032288 0.82 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr19_-_10946871 0.81 ENST00000589638.1
TMED1
transmembrane emp24 protein transport domain containing 1
chr18_-_61329118 0.79 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr19_+_54705025 0.79 ENST00000441429.1
RPS9
ribosomal protein S9
chr16_+_82068585 0.78 ENST00000563491.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr6_+_31783291 0.77 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
HSPA1A
heat shock 70kDa protein 1A
chr17_+_80186908 0.77 ENST00000582743.1
ENST00000578684.1
ENST00000577650.1
ENST00000582715.1
SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
chr12_-_92539614 0.77 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr17_-_39661947 0.77 ENST00000590425.1
KRT13
keratin 13
chr11_-_58275578 0.76 ENST00000360374.2
OR5B21
olfactory receptor, family 5, subfamily B, member 21
chr6_-_3157760 0.76 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr17_+_16284399 0.76 ENST00000535788.1
UBB
ubiquitin B
chr6_-_3227877 0.76 ENST00000259818.7
TUBB2B
tubulin, beta 2B class IIb
chrX_-_115594160 0.75 ENST00000371894.4
CXorf61
cancer/testis antigen 83
chr16_+_82068873 0.75 ENST00000566213.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr20_-_43753104 0.74 ENST00000372785.3
WFDC12
WAP four-disulfide core domain 12
chr6_-_10747802 0.74 ENST00000606522.1
ENST00000606652.1
RP11-421M1.8
RP11-421M1.8
chr15_-_41166414 0.74 ENST00000220507.4
RHOV
ras homolog family member V
chr12_+_27623565 0.73 ENST00000535986.1
SMCO2
single-pass membrane protein with coiled-coil domains 2
chr20_-_43883197 0.73 ENST00000338380.2
SLPI
secretory leukocyte peptidase inhibitor
chr11_-_64646086 0.73 ENST00000320631.3
EHD1
EH-domain containing 1
chr16_+_2880157 0.72 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr1_-_149814478 0.72 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr21_-_43735628 0.72 ENST00000291525.10
ENST00000518498.1
TFF3
trefoil factor 3 (intestinal)
chr21_-_43735446 0.72 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr19_+_572543 0.71 ENST00000333511.3
ENST00000573216.1
ENST00000353555.4
BSG
basigin (Ok blood group)
chr9_+_130911770 0.71 ENST00000372998.1
LCN2
lipocalin 2
chr17_-_39780819 0.70 ENST00000311208.8
KRT17
keratin 17
chr17_+_79849872 0.70 ENST00000584197.1
ENST00000583839.1
ANAPC11
anaphase promoting complex subunit 11
chr6_-_26216872 0.70 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr2_+_152214098 0.69 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_-_141338377 0.68 ENST00000510041.1
PCDH12
protocadherin 12
chr4_-_57547454 0.68 ENST00000556376.2
HOPX
HOP homeobox
chr16_+_89989687 0.68 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
TUBB3
Tubulin beta-3 chain
chr11_+_43964055 0.68 ENST00000528572.1
C11orf96
chromosome 11 open reading frame 96
chr8_-_73793975 0.67 ENST00000523881.1
RP11-1145L24.1
RP11-1145L24.1
chr5_+_43033818 0.67 ENST00000607830.1
CTD-2035E11.4
CTD-2035E11.4
chr12_-_49582837 0.67 ENST00000547939.1
ENST00000546918.1
ENST00000552924.1
TUBA1A
tubulin, alpha 1a
chr6_-_27860956 0.66 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr17_+_29248918 0.66 ENST00000581548.1
ENST00000580525.1
ADAP2
ArfGAP with dual PH domains 2
chr8_-_8639956 0.65 ENST00000522213.1
RP11-211C9.1
RP11-211C9.1
chr3_-_111314230 0.65 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr19_+_49375649 0.64 ENST00000200453.5
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr6_-_27840099 0.64 ENST00000328488.2
HIST1H3I
histone cluster 1, H3i
chr22_-_19466643 0.63 ENST00000474226.1
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr17_+_40458130 0.62 ENST00000587646.1
STAT5A
signal transducer and activator of transcription 5A
chr4_+_76481258 0.62 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr4_-_57547870 0.62 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chr19_+_49468558 0.61 ENST00000331825.6
FTL
ferritin, light polypeptide
chr14_-_55369525 0.61 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1
GTP cyclohydrolase 1
chr11_-_2950642 0.60 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr17_+_79849523 0.59 ENST00000572639.1
ENST00000579978.1
ENST00000344877.5
ENST00000582222.1
ENST00000577425.1
ENST00000571024.2
ENST00000574924.2
ENST00000572851.2
ENST00000357385.3
ENST00000584314.1
ENST00000571874.2
ENST00000578550.1
ENST00000577747.1
ENST00000579133.1
ANAPC11
anaphase promoting complex subunit 11
chr3_+_122044084 0.59 ENST00000264474.3
ENST00000479204.1
CSTA
cystatin A (stefin A)
chr19_+_18118972 0.58 ENST00000593560.2
ENST00000222250.4
ARRDC2
arrestin domain containing 2
chr11_+_68451943 0.58 ENST00000265643.3
GAL
galanin/GMAP prepropeptide
chr11_-_9025541 0.58 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
NRIP3
nuclear receptor interacting protein 3
chr1_+_144339738 0.57 ENST00000538264.1
AL592284.1
Protein LOC642441
chr22_-_19466454 0.55 ENST00000494054.1
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr10_-_47181681 0.54 ENST00000452267.1
FAM25B
family with sequence similarity 25, member B
chr17_+_17991218 0.54 ENST00000395726.4
ENST00000579601.1
ENST00000580929.1
ENST00000583355.1
DRG2
developmentally regulated GTP binding protein 2
chr16_-_2014804 0.54 ENST00000526522.1
ENST00000527302.1
ENST00000529806.1
ENST00000563194.1
ENST00000343262.4
RPS2
ribosomal protein S2
chr5_-_141338627 0.53 ENST00000231484.3
PCDH12
protocadherin 12
chr22_+_39916558 0.53 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr14_+_71108460 0.52 ENST00000256367.2
TTC9
tetratricopeptide repeat domain 9
chr4_+_22999152 0.52 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr19_+_12944722 0.52 ENST00000591495.1
MAST1
microtubule associated serine/threonine kinase 1
chr8_-_95220775 0.51 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr17_+_79849782 0.51 ENST00000392376.3
ANAPC11
anaphase promoting complex subunit 11
chr8_-_6735451 0.51 ENST00000297439.3
DEFB1
defensin, beta 1
chr14_+_75745477 0.50 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr19_+_54704990 0.49 ENST00000391753.2
RPS9
ribosomal protein S9
chr2_+_135596106 0.49 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr7_-_92777606 0.49 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr10_+_48247669 0.49 ENST00000457620.1
FAM25G
family with sequence similarity 25, member G
chr20_+_30193083 0.49 ENST00000376112.3
ENST00000376105.3
ID1
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr12_-_121476959 0.48 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr3_+_173116225 0.47 ENST00000457714.1
NLGN1
neuroligin 1
chr22_-_19466683 0.47 ENST00000399523.1
ENST00000421968.2
ENST00000447868.1
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr2_+_135596180 0.47 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr6_+_46761118 0.47 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr5_-_16742330 0.46 ENST00000505695.1
ENST00000427430.2
MYO10
myosin X
chr11_-_102714534 0.45 ENST00000299855.5
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr6_+_26217159 0.45 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr15_-_44969022 0.45 ENST00000560110.1
PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr6_-_137539651 0.44 ENST00000543628.1
IFNGR1
interferon gamma receptor 1
chr19_+_54704718 0.44 ENST00000391752.1
ENST00000402367.1
ENST00000391751.3
RPS9
ribosomal protein S9
chr3_+_75713481 0.43 ENST00000308062.3
ENST00000464571.1
FRG2C
FSHD region gene 2 family, member C
chr16_+_71392616 0.42 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
CALB2
calbindin 2
chr4_+_103422471 0.42 ENST00000226574.4
ENST00000394820.4
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr17_-_8113542 0.41 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
AURKB
aurora kinase B
chr5_-_180671172 0.41 ENST00000512805.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr17_+_60447579 0.41 ENST00000450662.2
EFCAB3
EF-hand calcium binding domain 3
chr22_+_29876197 0.40 ENST00000310624.6
NEFH
neurofilament, heavy polypeptide
chr17_-_39780634 0.40 ENST00000577817.2
KRT17
keratin 17
chr8_-_56987057 0.40 ENST00000518875.1
RPS20
ribosomal protein S20
chr19_+_34856078 0.40 ENST00000589399.1
ENST00000589640.1
ENST00000591204.1
GPI
glucose-6-phosphate isomerase
chr17_-_39781054 0.39 ENST00000463128.1
KRT17
keratin 17
chr1_+_41448820 0.39 ENST00000372616.1
CTPS1
CTP synthase 1
chr6_-_30585009 0.38 ENST00000376511.2
PPP1R10
protein phosphatase 1, regulatory subunit 10
chr17_-_73150599 0.38 ENST00000392566.2
ENST00000581874.1
HN1
hematological and neurological expressed 1
chr7_-_134143841 0.38 ENST00000285930.4
AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr14_+_93389425 0.38 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chr1_-_8086343 0.38 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERRFI1
ERBB receptor feedback inhibitor 1
chr17_+_74729060 0.38 ENST00000587459.1
RP11-318A15.7
Uncharacterized protein
chr6_+_27107053 0.37 ENST00000354348.2
HIST1H4I
histone cluster 1, H4i
chr16_+_58533951 0.37 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG4
NDRG family member 4
chr12_+_56435637 0.37 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr19_-_12912601 0.36 ENST00000334482.5
PRDX2
peroxiredoxin 2
chr1_-_95007193 0.36 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr20_+_31823091 0.35 ENST00000601172.1
AL121901.1
Nasopharyngeal carcinoma-related protein YH1; Uncharacterized protein
chr22_-_19466732 0.35 ENST00000263202.10
ENST00000360834.4
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr2_-_151344172 0.35 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr17_+_16284604 0.35 ENST00000395839.1
ENST00000395837.1
UBB
ubiquitin B
chr17_+_16284104 0.34 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
UBB
ubiquitin B
chr6_+_26199737 0.34 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr12_-_125399573 0.34 ENST00000339647.5
UBC
ubiquitin C
chr15_+_76629064 0.34 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr8_-_23261589 0.34 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
LOXL2
lysyl oxidase-like 2
chr5_-_180670880 0.34 ENST00000511566.1
ENST00000511900.1
ENST00000504726.1
ENST00000512968.1
ENST00000376817.4
ENST00000513027.1
ENST00000503081.1
ENST00000456394.2
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr1_+_31885963 0.34 ENST00000373709.3
SERINC2
serine incorporator 2
chr17_-_79849438 0.33 ENST00000331204.4
ENST00000505490.2
ALYREF
Aly/REF export factor
chr1_-_27481401 0.33 ENST00000263980.3
SLC9A1
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
chr7_+_129015484 0.33 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr6_-_27114577 0.32 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr6_-_15548591 0.32 ENST00000509674.1
DTNBP1
dystrobrevin binding protein 1
chr21_+_33031935 0.32 ENST00000270142.6
ENST00000389995.4
SOD1
superoxide dismutase 1, soluble
chr11_-_2160611 0.32 ENST00000416167.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr19_-_12912657 0.31 ENST00000301522.2
PRDX2
peroxiredoxin 2
chr21_+_45905448 0.30 ENST00000449713.1
AP001065.15
AP001065.15
chr22_+_41865109 0.30 ENST00000216254.4
ENST00000396512.3
ACO2
aconitase 2, mitochondrial
chr1_+_33546714 0.30 ENST00000294517.6
ENST00000358680.3
ENST00000373443.3
ENST00000398167.1
ADC
arginine decarboxylase
chr1_-_209825674 0.30 ENST00000367030.3
ENST00000356082.4
LAMB3
laminin, beta 3
chr17_-_4889508 0.30 ENST00000574606.2
CAMTA2
calmodulin binding transcription activator 2
chr3_+_193853927 0.30 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr17_+_39421591 0.30 ENST00000391355.1
KRTAP9-6
keratin associated protein 9-6
chr1_+_202830876 0.29 ENST00000456105.2
RP11-480I12.7
RP11-480I12.7
chr2_+_85132749 0.29 ENST00000233143.4
TMSB10
thymosin beta 10
chr6_+_27806319 0.29 ENST00000606613.1
ENST00000396980.3
HIST1H2BN
histone cluster 1, H2bn
chr14_-_47120956 0.29 ENST00000298283.3
RPL10L
ribosomal protein L10-like
chr12_-_121477039 0.28 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr18_-_33077942 0.28 ENST00000334598.7
INO80C
INO80 complex subunit C
chr1_-_1009683 0.28 ENST00000453464.2
RNF223
ring finger protein 223
chr12_+_13044787 0.28 ENST00000534831.1
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr7_+_142829162 0.28 ENST00000291009.3
PIP
prolactin-induced protein
chr20_+_55926625 0.28 ENST00000452119.1
RAE1
ribonucleic acid export 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.8 2.5 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.8 2.3 GO:2000627 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.7 2.0 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.6 3.6 GO:0097368 membrane to membrane docking(GO:0022614) establishment of Sertoli cell barrier(GO:0097368)
0.4 1.6 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.4 1.8 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.4 1.8 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 6.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.2 2.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.2 0.9 GO:0042710 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.2 0.6 GO:1902310 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.2 0.8 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 1.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 2.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 4.5 GO:0002544 chronic inflammatory response(GO:0002544)
0.2 1.6 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 0.6 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.2 0.8 GO:0035425 autocrine signaling(GO:0035425)
0.2 0.8 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.2 0.6 GO:0051795 positive regulation of catagen(GO:0051795)
0.2 7.8 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.2 0.5 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 11.9 GO:0018149 peptide cross-linking(GO:0018149)
0.2 1.4 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.2 0.5 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.2 0.5 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.2 0.6 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.3 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.4 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.1 1.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.4 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.1 2.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.4 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 0.4 GO:1900738 dense core granule biogenesis(GO:0061110) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 1.8 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.8 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 1.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.3 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.3 GO:0018277 protein deamination(GO:0018277)
0.1 0.3 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.1 0.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.4 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.5 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 1.9 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 1.6 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.5 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.5 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.2 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.4 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1 0.8 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.1 3.7 GO:0006953 acute-phase response(GO:0006953)
0.1 0.2 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 0.3 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.7 GO:0046689 response to mercury ion(GO:0046689)
0.1 0.3 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.6 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.2 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.1 0.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.9 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.3 GO:0035900 isocitrate metabolic process(GO:0006102) response to isolation stress(GO:0035900)
0.0 1.6 GO:0007398 ectoderm development(GO:0007398)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 1.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.4 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.9 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0032902 nerve growth factor production(GO:0032902)
0.0 0.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.7 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.4 GO:0046851 negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.0 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.4 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.7 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:0040031 snRNA modification(GO:0040031)
0.0 3.5 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.0 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.1 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.0 0.0 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.0 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.0 0.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 1.6 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.3 GO:0008211 glucocorticoid metabolic process(GO:0008211)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 2.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 11.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 12.9 GO:0001533 cornified envelope(GO:0001533)
0.2 2.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.5 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 0.7 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 4.5 GO:0000786 nucleosome(GO:0000786)
0.1 0.5 GO:1990037 Lewy body core(GO:1990037)
0.1 0.4 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 4.0 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.4 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 2.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 3.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.9 GO:0032433 filopodium tip(GO:0032433)
0.0 4.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0031906 late endosome lumen(GO:0031906) multivesicular body lumen(GO:0097486)
0.0 1.9 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 4.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.2 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.4 GO:0042583 chromaffin granule(GO:0042583)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 4.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 2.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.3 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 2.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0097386 glial cell projection(GO:0097386)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 2.8 GO:0034774 secretory granule lumen(GO:0034774)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.5 6.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 2.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.4 2.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.4 2.0 GO:0034711 inhibin binding(GO:0034711)
0.3 2.0 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2 10.2 GO:0042056 chemoattractant activity(GO:0042056)
0.2 1.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.5 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.2 0.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 1.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 1.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.6 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.3 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.1 0.8 GO:0005549 odorant binding(GO:0005549)
0.1 0.3 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 2.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.4 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 0.3 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.4 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.4 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 1.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.6 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.4 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.2 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.2 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 1.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 1.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 4.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0030346 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) protein phosphatase 2B binding(GO:0030346)
0.0 1.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.5 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 5.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 1.8 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 1.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 3.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 2.8 GO:0002020 protease binding(GO:0002020)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 1.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 3.4 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 13.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 6.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 2.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 2.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 10.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 8.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 4.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.4 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 1.8 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 3.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 2.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)