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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX15_MGA

Z-value: 0.99

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Transcription factors associated with TBX15_MGA

Gene Symbol Gene ID Gene Info
ENSG00000092607.9 T-box transcription factor 15
ENSG00000174197.12 MAX dimerization protein MGA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MGAhg19_v2_chr15_+_41952591_41952672-0.805.6e-02Click!
TBX15hg19_v2_chr1_-_119532127_1195321790.079.0e-01Click!

Activity profile of TBX15_MGA motif

Sorted Z-values of TBX15_MGA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_46531127 2.09 ENST00000601033.1
CTC-344H19.4
chr8_-_25281747 1.16 ENST00000421054.2
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr1_-_11907829 0.97 ENST00000376480.3
natriuretic peptide A
chr6_-_160166218 0.96 ENST00000537657.1
superoxide dismutase 2, mitochondrial
chr14_+_95078714 0.87 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr1_-_153066998 0.73 ENST00000368750.3
small proline-rich protein 2E
chr2_+_228678550 0.73 ENST00000409189.3
ENST00000358813.4
chemokine (C-C motif) ligand 20
chr3_+_167453026 0.59 ENST00000472941.1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr20_+_44098346 0.53 ENST00000372676.3
WAP four-disulfide core domain 2
chr6_+_30295036 0.51 ENST00000376659.5
ENST00000428555.1
tripartite motif containing 39
chr6_+_32132360 0.48 ENST00000333845.6
ENST00000395512.1
ENST00000432129.1
EGF-like-domain, multiple 8
chr22_+_27068766 0.47 ENST00000435162.1
ENST00000437071.1
ENST00000440816.1
ENST00000421253.1
CTA-211A9.5
chr21_+_30503282 0.44 ENST00000399925.1
MAP3K7 C-terminal like
chr12_+_56473939 0.44 ENST00000450146.2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr6_+_30294612 0.43 ENST00000440271.1
ENST00000396551.3
ENST00000376656.4
ENST00000540416.1
ENST00000428728.1
ENST00000396548.1
ENST00000428404.1
tripartite motif containing 39
chr7_-_76255444 0.42 ENST00000454397.1
POM121 and ZP3 fusion
chr7_-_143956815 0.41 ENST00000493325.1
olfactory receptor, family 2, subfamily A, member 7
chr4_+_57371509 0.40 ENST00000360096.2
ADP-ribosylation factor-like 9
chr2_+_154728426 0.40 ENST00000392825.3
ENST00000434213.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr19_-_14016877 0.40 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
chromosome 19 open reading frame 57
chr11_+_93754513 0.39 ENST00000315765.9
hephaestin-like 1
chr6_-_31620095 0.39 ENST00000424176.1
ENST00000456622.1
BCL2-associated athanogene 6
chr17_-_7232585 0.37 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
neuralized E3 ubiquitin protein ligase 4
chr11_+_120081475 0.37 ENST00000328965.4
OAF homolog (Drosophila)
chr7_+_143013198 0.37 ENST00000343257.2
chloride channel, voltage-sensitive 1
chr8_+_73449625 0.36 ENST00000523207.1
potassium voltage-gated channel, Shab-related subfamily, member 2
chr17_-_1619568 0.35 ENST00000571595.1
MIR22 host gene (non-protein coding)
chr17_-_46657473 0.35 ENST00000332503.5
homeobox B4
chr12_-_58145889 0.35 ENST00000547853.1
cyclin-dependent kinase 4
chr17_+_77021702 0.35 ENST00000392445.2
ENST00000354124.3
C1q and tumor necrosis factor related protein 1
chr1_+_26737253 0.34 ENST00000326279.6
lin-28 homolog A (C. elegans)
chr6_-_31619697 0.34 ENST00000434444.1
BCL2-associated athanogene 6
chr12_+_57853918 0.34 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI family zinc finger 1
chr20_+_44098385 0.34 ENST00000217425.5
ENST00000339946.3
WAP four-disulfide core domain 2
chr12_-_96793142 0.33 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
cyclin-dependent kinase 17
chr11_+_7559485 0.32 ENST00000527790.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_-_146859623 0.32 ENST00000379448.4
ENST00000513320.1
zinc finger protein 827
chr9_-_140082983 0.32 ENST00000323927.2
anaphase promoting complex subunit 2
chrX_+_46772065 0.32 ENST00000455411.1
jade family PHD finger 3
chr1_-_113257905 0.31 ENST00000464951.1
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr3_-_49459878 0.31 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
aminomethyltransferase
chr17_-_57784755 0.31 ENST00000537860.1
ENST00000393038.2
ENST00000409433.2
peptidyl-tRNA hydrolase 2
chr19_+_55987998 0.30 ENST00000591164.1
zinc finger protein 628
chr8_-_11660077 0.30 ENST00000533405.1
Uncharacterized protein
chr5_-_147286065 0.30 ENST00000318315.4
ENST00000515291.1
chromosome 5 open reading frame 46
chr1_-_153044083 0.30 ENST00000341611.2
small proline-rich protein 2B
chr11_-_111749767 0.29 ENST00000542429.1
ferredoxin-fold anticodon binding domain containing 1
chr20_+_44509857 0.28 ENST00000372523.1
ENST00000372520.1
zinc finger, SWIM-type containing 1
chr3_+_52422899 0.28 ENST00000480649.1
dynein, axonemal, heavy chain 1
chr6_-_31619742 0.28 ENST00000433828.1
ENST00000456286.1
BCL2-associated athanogene 6
chr1_+_38512799 0.28 ENST00000432922.1
ENST00000428151.1
RP5-884C9.2
chr1_-_26633067 0.28 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBX domain protein 11
chr4_+_160188889 0.27 ENST00000264431.4
Rap guanine nucleotide exchange factor (GEF) 2
chr11_+_107643129 0.27 ENST00000447610.1
Uncharacterized protein
chr17_-_76356148 0.27 ENST00000587578.1
ENST00000330871.2
suppressor of cytokine signaling 3
chr12_+_53400176 0.26 ENST00000551002.1
ENST00000420463.3
ENST00000416762.3
ENST00000549481.1
ENST00000552490.1
eukaryotic translation initiation factor 4B
chr6_-_30815936 0.26 ENST00000442852.1
XXbac-BPG27H4.8
chr12_-_25801478 0.26 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
intermediate filament tail domain containing 1
chr17_+_25958174 0.26 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
lectin, galactoside-binding, soluble, 9
chr3_-_109056419 0.25 ENST00000335658.6
developmental pluripotency associated 4
chr18_-_30050395 0.25 ENST00000269209.6
ENST00000399218.4
GRB2 associated, regulator of MAPK1
chr11_+_111749650 0.25 ENST00000528125.1
chromosome 11 open reading frame 1
chr15_+_76016293 0.25 ENST00000332145.2
outer dense fiber of sperm tails 3-like 1
chr7_-_27135591 0.25 ENST00000343060.4
ENST00000355633.5
homeobox A1
chrX_-_19689106 0.24 ENST00000379716.1
SH3-domain kinase binding protein 1
chr1_+_27114418 0.24 ENST00000078527.4
phosphatidylinositol glycan anchor biosynthesis, class V
chr1_+_145507587 0.24 ENST00000330165.8
ENST00000369307.3
RNA binding motif protein 8A
chr11_+_61447845 0.23 ENST00000257215.5
diacylglycerol lipase, alpha
chr5_-_137514333 0.23 ENST00000411594.2
ENST00000430331.1
bromodomain containing 8
chr4_-_186732241 0.23 ENST00000421639.1
sorbin and SH3 domain containing 2
chr16_-_2205352 0.23 ENST00000563192.1
RP11-304L19.5
chr17_+_63096903 0.23 ENST00000582940.1
RP11-160O5.1
chr8_-_22549856 0.22 ENST00000522910.1
early growth response 3
chr1_-_153029980 0.22 ENST00000392653.2
small proline-rich protein 2A
chrX_-_106146547 0.22 ENST00000276173.4
ENST00000411805.1
ripply transcriptional repressor 1
chr6_-_31619892 0.22 ENST00000454165.1
ENST00000428326.1
ENST00000452994.1
BCL2-associated athanogene 6
chr16_-_69418553 0.22 ENST00000569542.2
telomeric repeat binding factor 2
chr4_-_44450814 0.22 ENST00000360029.3
potassium channel tetramerization domain containing 8
chr1_+_38022513 0.22 ENST00000296218.7
dynein, axonemal, light intermediate chain 1
chr17_+_76210367 0.22 ENST00000592734.1
ENST00000587746.1
baculoviral IAP repeat containing 5
chr1_-_205290865 0.21 ENST00000367157.3
NUAK family, SNF1-like kinase, 2
chr16_+_77233294 0.21 ENST00000378644.4
synaptonemal complex central element protein 1-like
chr19_-_42721819 0.21 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
death effector domain containing 2
chr11_-_125932685 0.21 ENST00000527967.1
cell adhesion associated, oncogene regulated
chr21_+_30502806 0.21 ENST00000399928.1
ENST00000399926.1
MAP3K7 C-terminal like
chr12_+_58148842 0.21 ENST00000266643.5
membrane-associated ring finger (C3HC4) 9
chr1_+_15736359 0.21 ENST00000375980.4
EF-hand domain family, member D2
chr1_+_26737292 0.20 ENST00000254231.4
lin-28 homolog A (C. elegans)
chr6_-_31620149 0.20 ENST00000435080.1
ENST00000375976.4
ENST00000441054.1
BCL2-associated athanogene 6
chr12_-_18890940 0.20 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
phospholipase C, zeta 1
chr5_+_140571902 0.20 ENST00000239446.4
protocadherin beta 10
chr16_-_81110683 0.19 ENST00000565253.1
ENST00000378611.4
ENST00000299578.5
chromosome 16 open reading frame 46
chr2_-_175869936 0.19 ENST00000409900.3
chimerin 1
chrX_+_15808569 0.19 ENST00000380308.3
ENST00000307771.7
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr21_+_30968360 0.19 ENST00000333765.4
GRIK1 antisense RNA 2
chr2_-_39664206 0.19 ENST00000484274.1
mitogen-activated protein kinase kinase kinase kinase 3
chr17_-_1553346 0.19 ENST00000301336.6
Rab interacting lysosomal protein
chr11_-_133826852 0.19 ENST00000533871.2
ENST00000321016.8
immunoglobulin superfamily, member 9B
chr8_-_82395461 0.18 ENST00000256104.4
fatty acid binding protein 4, adipocyte
chr7_+_76090993 0.18 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
deltex homolog 2 (Drosophila)
chr7_-_71801980 0.18 ENST00000329008.5
calneuron 1
chr7_+_34697846 0.18 ENST00000381553.3
ENST00000465305.1
ENST00000360581.1
ENST00000381542.1
ENST00000359791.1
ENST00000531252.1
neuropeptide S receptor 1
chr9_+_140083099 0.18 ENST00000322310.5
Sjogren syndrome nuclear autoantigen 1
chrX_+_107334983 0.18 ENST00000457035.1
ENST00000545696.1
autophagy related 4A, cysteine peptidase
chr11_-_119599794 0.18 ENST00000264025.3
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr3_+_127770455 0.17 ENST00000464451.1
Sec61 alpha 1 subunit (S. cerevisiae)
chr17_+_9066252 0.17 ENST00000436734.1
netrin 1
chr16_-_66968055 0.17 ENST00000568572.1
family with sequence similarity 96, member B
chrM_+_10758 0.17 ENST00000361381.2
mitochondrially encoded NADH dehydrogenase 4
chr11_-_6502580 0.17 ENST00000423813.2
ENST00000396777.3
ADP-ribosylation factor interacting protein 2
chrX_-_70473957 0.17 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
zinc finger, MYM-type 3
chr11_-_6502534 0.17 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ADP-ribosylation factor interacting protein 2
chr11_+_18477369 0.17 ENST00000396213.3
ENST00000280706.2
lactate dehydrogenase A-like 6A
chr1_-_25256368 0.16 ENST00000308873.6
runt-related transcription factor 3
chr11_-_111749878 0.16 ENST00000260257.4
ferredoxin-fold anticodon binding domain containing 1
chr20_+_1115821 0.16 ENST00000435720.1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr9_+_34990219 0.16 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DnaJ (Hsp40) homolog, subfamily B, member 5
chr19_+_3762645 0.16 ENST00000330133.4
mitochondrial ribosomal protein L54
chr7_+_140373619 0.16 ENST00000483369.1
aarF domain containing kinase 2
chr4_-_186456652 0.16 ENST00000284767.5
ENST00000284770.5
PDZ and LIM domain 3
chr20_+_2517253 0.16 ENST00000358864.1
transmembrane channel-like 2
chr6_-_13487825 0.16 ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chrX_+_56259316 0.16 ENST00000468660.1
Kruppel-like factor 8
chr17_-_46682321 0.16 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr16_+_4666475 0.16 ENST00000591895.1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr17_+_76356516 0.15 ENST00000592569.1
RP11-806H10.4
chr3_-_66551351 0.15 ENST00000273261.3
leucine-rich repeats and immunoglobulin-like domains 1
chr17_-_79869077 0.15 ENST00000570391.1
phosphate cytidylyltransferase 2, ethanolamine
chr4_-_186456766 0.15 ENST00000284771.6
PDZ and LIM domain 3
chr15_-_83316254 0.15 ENST00000567678.1
ENST00000450751.2
cytoplasmic polyadenylation element binding protein 1
chrX_-_138287168 0.15 ENST00000436198.1
fibroblast growth factor 13
chr3_-_39196049 0.15 ENST00000514182.1
cysteine-serine-rich nuclear protein 1
chr18_-_45457192 0.15 ENST00000586514.1
ENST00000591214.1
ENST00000589877.1
SMAD family member 2
chr14_-_65569244 0.15 ENST00000557277.1
ENST00000556892.1
MYC associated factor X
chr1_-_161039753 0.15 ENST00000368015.1
Rho GTPase activating protein 30
chr17_+_47653471 0.14 ENST00000513748.1
neurexophilin 3
chr11_+_73358690 0.14 ENST00000545798.1
ENST00000539157.1
ENST00000546251.1
ENST00000535582.1
ENST00000538227.1
ENST00000543524.1
pleckstrin homology domain containing, family B (evectins) member 1
chr19_+_3762703 0.14 ENST00000589174.1
mitochondrial ribosomal protein L54
chr16_-_67450325 0.14 ENST00000348579.2
zinc finger, DHHC-type containing 1
chr1_+_41445413 0.14 ENST00000541520.1
CTP synthase 1
chr1_+_204485571 0.14 ENST00000454264.2
ENST00000367183.3
Mdm4 p53 binding protein homolog (mouse)
chr2_-_27718052 0.14 ENST00000264703.3
fibronectin type III domain containing 4
chr17_-_79869340 0.14 ENST00000538936.2
phosphate cytidylyltransferase 2, ethanolamine
chr11_+_73358594 0.14 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
pleckstrin homology domain containing, family B (evectins) member 1
chrX_+_122318113 0.14 ENST00000371264.3
glutamate receptor, ionotropic, AMPA 3
chr14_+_55033815 0.14 ENST00000554335.1
sterile alpha motif domain containing 4A
chr12_-_49351228 0.14 ENST00000541959.1
ENST00000447318.2
ADP-ribosylation factor 3
chr5_-_139283982 0.14 ENST00000340391.3
neuregulin 2
chr12_-_50101003 0.14 ENST00000550488.1
formin-like 3
chr8_+_11660227 0.14 ENST00000443614.2
ENST00000525900.1
farnesyl-diphosphate farnesyltransferase 1
chr17_-_79869243 0.14 ENST00000538721.2
ENST00000573636.2
ENST00000571105.1
ENST00000576343.1
ENST00000572473.1
phosphate cytidylyltransferase 2, ethanolamine
chr1_-_161039647 0.14 ENST00000368013.3
Rho GTPase activating protein 30
chr9_+_75766652 0.14 ENST00000257497.6
annexin A1
chr11_-_124981475 0.14 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr9_+_102584128 0.13 ENST00000338488.4
ENST00000395097.2
nuclear receptor subfamily 4, group A, member 3
chr10_+_7860460 0.13 ENST00000344293.5
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
chr17_-_1012305 0.13 ENST00000291107.2
active BCR-related
chr1_+_8378140 0.13 ENST00000377479.2
solute carrier family 45, member 1
chr12_-_102133191 0.13 ENST00000392924.1
ENST00000266743.2
ENST00000392927.3
synaptonemal complex protein 3
chr5_-_88180342 0.13 ENST00000502983.1
myocyte enhancer factor 2C
chr1_+_165796753 0.13 ENST00000367879.4
uridine-cytidine kinase 2
chr1_+_207002222 0.13 ENST00000270218.6
interleukin 19
chr20_+_44657845 0.13 ENST00000243964.3
solute carrier family 12 (potassium/chloride transporter), member 5
chr22_+_39966758 0.13 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
calcium channel, voltage-dependent, T type, alpha 1I subunit
chrX_-_70474499 0.13 ENST00000353904.2
zinc finger, MYM-type 3
chr17_-_74533734 0.13 ENST00000589342.1
cytoglobin
chr10_-_131762105 0.13 ENST00000368648.3
ENST00000355311.5
early B-cell factor 3
chr17_-_47755338 0.13 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
speckle-type POZ protein
chr5_+_176560595 0.13 ENST00000508896.1
nuclear receptor binding SET domain protein 1
chr11_-_76155618 0.13 ENST00000530759.1
RP11-111M22.3
chr21_-_42880075 0.13 ENST00000332149.5
transmembrane protease, serine 2
chr17_-_79869004 0.13 ENST00000573927.1
ENST00000331285.3
ENST00000572157.1
phosphate cytidylyltransferase 2, ethanolamine
chr17_-_7120525 0.13 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
discs, large homolog 4 (Drosophila)
chr3_+_186330712 0.13 ENST00000411641.2
ENST00000273784.5
alpha-2-HS-glycoprotein
chr19_+_45973120 0.13 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr15_+_41062159 0.12 ENST00000344320.6
chromosome 15 open reading frame 62
chr3_+_63805017 0.12 ENST00000295896.8
chromosome 3 open reading frame 49
chr20_+_62492566 0.12 ENST00000369916.3
abhydrolase domain containing 16B
chr19_-_6333614 0.12 ENST00000301452.4
alkaline ceramidase 1
chr14_+_55034599 0.12 ENST00000392067.3
ENST00000357634.3
sterile alpha motif domain containing 4A
chrX_+_54556633 0.12 ENST00000336470.4
ENST00000360845.2
guanine nucleotide binding protein-like 3 (nucleolar)-like
chr11_+_10772847 0.12 ENST00000524523.1
CTR9, Paf1/RNA polymerase II complex component
chr17_+_73257742 0.12 ENST00000579761.1
ENST00000245539.6
mitochondrial ribosomal protein S7
chr7_-_20826504 0.12 ENST00000418710.2
ENST00000361443.4
Sp8 transcription factor
chr3_+_160117062 0.12 ENST00000497311.1
structural maintenance of chromosomes 4
chr21_-_42879909 0.12 ENST00000458356.1
ENST00000398585.3
ENST00000424093.1
transmembrane protease, serine 2
chrM_+_10464 0.12 ENST00000361335.1
mitochondrially encoded NADH dehydrogenase 4L
chr6_-_130536774 0.12 ENST00000532763.1
sterile alpha motif domain containing 3
chr3_+_107364683 0.12 ENST00000413213.1
bobby sox homolog (Drosophila)
chr5_-_132112907 0.12 ENST00000458488.2
septin 8
chr8_-_123793048 0.12 ENST00000607710.1
RP11-44N11.2
chr1_-_113258090 0.12 ENST00000309276.6
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr2_-_74776586 0.12 ENST00000420535.1
lysyl oxidase-like 3
chr8_+_56014949 0.12 ENST00000327381.6
XK, Kell blood group complex subunit-related family, member 4
chr9_-_34397800 0.11 ENST00000297623.2
chromosome 9 open reading frame 24
chr6_+_108616243 0.11 ENST00000421954.1
lactation elevated 1
chr5_+_110407390 0.11 ENST00000344895.3
thymic stromal lymphopoietin
chr7_-_99527243 0.11 ENST00000312891.2
gap junction protein, gamma 3, 30.2kDa
chr5_-_132112921 0.11 ENST00000378721.4
ENST00000378701.1
septin 8
chr8_-_95907423 0.11 ENST00000396133.3
ENST00000308108.4
cyclin E2

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX15_MGA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:1990637 response to prolactin(GO:1990637)
0.2 0.7 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 1.0 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.2 1.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 1.4 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) natural killer cell tolerance induction(GO:0002519) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.2 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.4 GO:0035803 egg coat formation(GO:0035803)
0.1 0.2 GO:2001280 myoblast migration involved in skeletal muscle regeneration(GO:0014839) positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.2 GO:0007343 egg activation(GO:0007343)
0.1 0.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.2 GO:0014028 notochord formation(GO:0014028)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.2 GO:0060032 notochord regression(GO:0060032)
0.1 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.4 GO:0048539 bone marrow development(GO:0048539)
0.0 0.3 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.9 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.1 GO:1900205 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.1 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.3 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:1903824 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.0 0.3 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.5 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0071506 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.1 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:2000848 positive regulation of corticosteroid hormone secretion(GO:2000848)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.0 GO:1904204 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.1 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.0 0.1 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.0 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.0 GO:0031929 TOR signaling(GO:0031929) regulation of TOR signaling(GO:0032006)
0.0 0.1 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.1 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.0 GO:0072040 regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072039) negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072040) mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:1901145) negative regulation of somatic stem cell population maintenance(GO:1904673)
0.0 1.2 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:0007507 heart development(GO:0007507)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.0 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.1 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.0 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.0 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.0 GO:0061145 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.0 GO:0061386 noradrenergic neuron differentiation(GO:0003357) closure of optic fissure(GO:0061386)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.3 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.0 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.0 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.0 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0098759 interleukin-8-mediated signaling pathway(GO:0038112) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.2 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.0 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.5 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.4 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 1.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 1.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.0 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 0.9 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.7 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 0.4 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.1 1.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.4 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.3 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 1.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.0 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.1 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.0 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.0 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.0 PID FOXO PATHWAY FoxO family signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling