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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX2

Z-value: 0.62

Motif logo

Transcription factors associated with TBX2

Gene Symbol Gene ID Gene Info
ENSG00000121068.9 T-box transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX2hg19_v2_chr17_+_59477233_59477263-0.513.0e-01Click!

Activity profile of TBX2 motif

Sorted Z-values of TBX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_103876528 0.43 ENST00000522939.1
ENST00000524007.1
HCG15011, isoform CRA_a; Protein LOC100996457
chr6_-_110500826 0.42 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WAS protein family, member 1
chr1_+_35734616 0.40 ENST00000441447.1
zinc finger, MYM-type 4
chr14_+_21467414 0.40 ENST00000554422.1
ENST00000298681.4
solute carrier family 39 (zinc transporter), member 2
chr7_+_107220899 0.40 ENST00000379117.2
ENST00000473124.1
B-cell receptor-associated protein 29
chr3_+_142315294 0.36 ENST00000464320.1
plastin 1
chr7_+_107220660 0.34 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
B-cell receptor-associated protein 29
chr11_-_18956556 0.32 ENST00000302797.3
MAS-related GPR, member X1
chr2_+_29033682 0.32 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
speedy/RINGO cell cycle regulator family member A
chr2_+_102758271 0.31 ENST00000428279.1
interleukin 1 receptor, type I
chr5_-_138780159 0.27 ENST00000512473.1
ENST00000515581.1
ENST00000515277.1
DnaJ (Hsp40) homolog, subfamily C, member 18
chr19_-_43702231 0.24 ENST00000597374.1
ENST00000599371.1
pregnancy specific beta-1-glycoprotein 4
chr17_-_60005365 0.24 ENST00000444766.3
integrator complex subunit 2
chr1_-_183387723 0.23 ENST00000287713.6
nicotinamide nucleotide adenylyltransferase 2
chr7_-_108209897 0.23 ENST00000313516.5
THAP domain containing 5
chr8_-_99954788 0.22 ENST00000523601.1
serine/threonine kinase 3
chr3_+_121554046 0.22 ENST00000273668.2
ENST00000451944.2
ELL associated factor 2
chr3_+_142315225 0.21 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
plastin 1
chr3_-_194207388 0.21 ENST00000457986.1
ATPase type 13A3
chr11_-_112034831 0.21 ENST00000280357.7
interleukin 18 (interferon-gamma-inducing factor)
chr12_+_65672702 0.20 ENST00000538045.1
ENST00000535239.1
methionine sulfoxide reductase B3
chr20_-_45530365 0.20 ENST00000414085.1
RP11-323C15.2
chr11_+_66790816 0.19 ENST00000527043.1
synaptotagmin XII
chr1_+_144989309 0.19 ENST00000596396.1
Uncharacterized protein
chr17_+_46185111 0.19 ENST00000582104.1
ENST00000584335.1
sorting nexin 11
chr8_-_27457494 0.17 ENST00000521770.1
clusterin
chr4_-_89619386 0.17 ENST00000323061.5
nucleosome assembly protein 1-like 5
chr7_-_127032741 0.17 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
zinc finger protein 800
chr16_-_4303767 0.17 ENST00000573268.1
ENST00000573042.1
RP11-95P2.1
chr2_+_189156586 0.16 ENST00000409830.1
GULP, engulfment adaptor PTB domain containing 1
chr2_-_169769787 0.16 ENST00000451987.1
SPC25, NDC80 kinetochore complex component
chr11_-_111649074 0.16 ENST00000534218.1
RP11-108O10.2
chr10_+_135050908 0.16 ENST00000325980.9
VENT homeobox
chr19_+_50832943 0.16 ENST00000542413.1
nuclear receptor subfamily 1, group H, member 2
chr9_+_114287433 0.16 ENST00000358151.4
ENST00000355824.3
ENST00000374374.3
ENST00000309235.5
zinc finger protein 483
chr9_+_26956474 0.16 ENST00000429045.2
intraflagellar transport 74 homolog (Chlamydomonas)
chr20_+_34020827 0.15 ENST00000374375.1
growth differentiation factor 5 opposite strand
chr2_+_102758210 0.15 ENST00000450319.1
interleukin 1 receptor, type I
chr3_+_129207033 0.15 ENST00000507221.1
intraflagellar transport 122 homolog (Chlamydomonas)
chr22_-_29138386 0.15 ENST00000544772.1
checkpoint kinase 2
chr5_-_64858944 0.14 ENST00000508421.1
ENST00000510693.1
ENST00000514814.1
ENST00000515497.1
ENST00000396679.1
centromere protein K
chrX_-_119693745 0.14 ENST00000371323.2
cullin 4B
chr2_+_102758751 0.14 ENST00000442590.1
interleukin 1 receptor, type I
chr2_-_105953912 0.14 ENST00000610036.1
RP11-332H14.2
chr15_-_55581954 0.14 ENST00000336787.1
RAB27A, member RAS oncogene family
chr12_-_12849073 0.14 ENST00000332427.2
ENST00000540796.1
G protein-coupled receptor 19
chr17_-_36884451 0.14 ENST00000595377.1
NS5ATP13TP1; Uncharacterized protein
chr12_+_32112340 0.14 ENST00000540924.1
ENST00000312561.4
KIAA1551
chr1_-_205391178 0.14 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEM domain containing 1
chr19_+_50832895 0.13 ENST00000600355.1
nuclear receptor subfamily 1, group H, member 2
chr8_+_145490549 0.13 ENST00000340695.2
scleraxis homolog A (mouse)
chr4_-_186732048 0.13 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
sorbin and SH3 domain containing 2
chr15_+_69373210 0.13 ENST00000435479.1
ENST00000559870.1
long intergenic non-protein coding RNA 277
RP11-809H16.5
chr14_+_21525981 0.13 ENST00000308227.2
ribonuclease, RNase A family, 8
chr14_-_45603657 0.13 ENST00000396062.3
FK506 binding protein 3, 25kDa
chr6_-_105584560 0.13 ENST00000336775.5
blood vessel epicardial substance
chr15_-_52030293 0.13 ENST00000560491.1
ENST00000267838.3
LysM, putative peptidoglycan-binding, domain containing 2
chr11_+_20409070 0.13 ENST00000331079.6
protein arginine methyltransferase 3
chr11_+_122709200 0.12 ENST00000227348.4
cytotoxic and regulatory T cell molecule
chr11_-_71751715 0.12 ENST00000535947.1
nuclear mitotic apparatus protein 1
chr9_-_35042824 0.12 ENST00000595331.1
FLJ00273
chr1_+_38022572 0.12 ENST00000541606.1
dynein, axonemal, light intermediate chain 1
chr6_-_97731019 0.12 ENST00000275053.4
MMS22-like, DNA repair protein
chr11_+_114271251 0.12 ENST00000375490.5
RNA binding motif protein 7
chr14_+_32546274 0.12 ENST00000396582.2
Rho GTPase activating protein 5
chr17_-_15165854 0.12 ENST00000395936.1
ENST00000395938.2
peripheral myelin protein 22
chr12_+_11905413 0.11 ENST00000545027.1
ets variant 6
chr14_-_55658323 0.11 ENST00000554067.1
ENST00000247191.2
discs, large (Drosophila) homolog-associated protein 5
chr22_-_51001332 0.11 ENST00000406915.3
synaptonemal complex central element protein 3
chr4_-_4249924 0.11 ENST00000254742.2
ENST00000382753.4
ENST00000540397.1
ENST00000538516.1
transmembrane protein 128
chr3_-_197024394 0.11 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
discs, large homolog 1 (Drosophila)
chr16_+_30212378 0.11 ENST00000569485.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chrX_-_119709637 0.11 ENST00000404115.3
cullin 4B
chr14_+_32546145 0.11 ENST00000556611.1
ENST00000539826.2
Rho GTPase activating protein 5
chr13_-_48669232 0.11 ENST00000258648.2
ENST00000378586.1
mediator complex subunit 4
chr16_+_16481306 0.11 ENST00000422673.2
nuclear pore complex interacting protein family, member A7
chr22_+_40441456 0.11 ENST00000402203.1
trinucleotide repeat containing 6B
chr3_-_119379719 0.11 ENST00000493094.1
popeye domain containing 2
chr1_-_52456352 0.10 ENST00000371655.3
RAB3B, member RAS oncogene family
chr12_+_65672423 0.10 ENST00000355192.3
ENST00000308259.5
ENST00000540804.1
ENST00000535664.1
ENST00000541189.1
methionine sulfoxide reductase B3
chr11_-_114271139 0.10 ENST00000325636.4
chromosome 11 open reading frame 71
chr8_-_124428569 0.10 ENST00000521903.1
ATPase family, AAA domain containing 2
chr9_+_40028620 0.10 ENST00000426179.1
AL353791.1
chr11_-_16430399 0.10 ENST00000528252.1
SRY (sex determining region Y)-box 6
chr1_-_205744205 0.10 ENST00000446390.2
RAB7, member RAS oncogene family-like 1
chr7_-_48019101 0.10 ENST00000432627.1
ENST00000258774.5
ENST00000432325.1
ENST00000446009.1
HUS1 checkpoint homolog (S. pombe)
chr2_+_53994927 0.10 ENST00000295304.4
ChaC, cation transport regulator homolog 2 (E. coli)
chr9_+_26956371 0.10 ENST00000380062.5
ENST00000518614.1
intraflagellar transport 74 homolog (Chlamydomonas)
chr2_-_75796837 0.10 ENST00000233712.1
eva-1 homolog A (C. elegans)
chr7_+_108210012 0.09 ENST00000249356.3
DnaJ (Hsp40) homolog, subfamily B, member 9
chr17_-_60005329 0.09 ENST00000251334.6
integrator complex subunit 2
chr7_+_114562172 0.09 ENST00000393486.1
ENST00000257724.3
MyoD family inhibitor domain containing
chr5_+_137514403 0.09 ENST00000513276.1
kinesin family member 20A
chr19_+_46000506 0.09 ENST00000396737.2
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr1_+_172628154 0.09 ENST00000340030.3
ENST00000367721.2
Fas ligand (TNF superfamily, member 6)
chr4_-_153700864 0.09 ENST00000304337.2
tigger transposable element derived 4
chr11_+_114270752 0.09 ENST00000540163.1
RNA binding motif protein 7
chr9_+_127023704 0.09 ENST00000373596.1
ENST00000425237.1
NIMA-related kinase 6
chr19_-_41942344 0.09 ENST00000594660.1
ATP5S-like
chr3_+_32726774 0.09 ENST00000538368.1
CCR4-NOT transcription complex, subunit 10
chr2_+_201994042 0.09 ENST00000417748.1
CASP8 and FADD-like apoptosis regulator
chr14_-_55658252 0.09 ENST00000395425.2
discs, large (Drosophila) homolog-associated protein 5
chr3_+_112930387 0.09 ENST00000485230.1
BOC cell adhesion associated, oncogene regulated
chr8_-_90769422 0.09 ENST00000524190.1
ENST00000523859.1
RP11-37B2.1
chr20_-_1165117 0.09 ENST00000381894.3
transmembrane protein 74B
chr7_-_7782204 0.09 ENST00000418534.2
AC007161.5
chr14_+_77582905 0.09 ENST00000557408.1
transmembrane protein 63C
chr9_-_134585221 0.08 ENST00000372190.3
ENST00000427994.1
Rap guanine nucleotide exchange factor (GEF) 1
chr14_-_35183755 0.08 ENST00000555765.1
cofilin 2 (muscle)
chr11_-_28129656 0.08 ENST00000263181.6
kinesin family member 18A
chrX_-_53461288 0.08 ENST00000375298.4
ENST00000375304.5
hydroxysteroid (17-beta) dehydrogenase 10
chr5_-_68628543 0.08 ENST00000396496.2
ENST00000511257.1
ENST00000383374.2
coiled-coil domain containing 125
chr17_+_30771279 0.08 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr19_-_44405941 0.08 ENST00000587128.1
RP11-15A1.3
chr2_+_120770581 0.08 ENST00000263713.5
erythrocyte membrane protein band 4.1 like 5
chr4_+_140222609 0.08 ENST00000296543.5
ENST00000398947.1
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr4_+_141445333 0.08 ENST00000507667.1
ELMO/CED-12 domain containing 2
chr19_+_52264449 0.08 ENST00000599326.1
ENST00000598953.1
formyl peptide receptor 2
chr2_-_148778323 0.08 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
origin recognition complex, subunit 4
chr3_+_183967409 0.08 ENST00000324557.4
ENST00000402825.3
endothelin converting enzyme 2
chrX_-_53461305 0.08 ENST00000168216.6
hydroxysteroid (17-beta) dehydrogenase 10
chrX_+_105412290 0.08 ENST00000357175.2
ENST00000337685.2
melanoma associated antigen (mutated) 1-like 1
chr6_-_33679452 0.08 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
ubiquinol-cytochrome c reductase complex assembly factor 2
chr9_+_33750515 0.08 ENST00000361005.5
protease, serine, 3
chr3_+_4535155 0.08 ENST00000544951.1
inositol 1,4,5-trisphosphate receptor, type 1
chr19_-_37407172 0.08 ENST00000391711.3
zinc finger protein 829
chr12_-_57443886 0.08 ENST00000300119.3
myosin IA
chr3_+_185431080 0.08 ENST00000296270.1
chromosome 3 open reading frame 65
chr5_+_110559312 0.08 ENST00000508074.1
calcium/calmodulin-dependent protein kinase IV
chr1_+_100111479 0.08 ENST00000263174.4
palmdelphin
chr1_-_245026388 0.08 ENST00000440865.1
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr3_-_61237050 0.08 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
fragile histidine triad
chr1_-_150780757 0.08 ENST00000271651.3
cathepsin K
chr12_-_8815404 0.07 ENST00000359478.2
ENST00000396549.2
microfibrillar associated protein 5
chr6_+_83777374 0.07 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
dopey family member 1
chr6_-_86099898 0.07 ENST00000455071.1
RP11-30P6.6
chr11_+_111412271 0.07 ENST00000528102.1
layilin
chr22_+_18593097 0.07 ENST00000426208.1
tubulin, alpha 8
chr3_+_184016986 0.07 ENST00000417952.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr1_+_178482262 0.07 ENST00000367641.3
ENST00000367639.1
testis expressed 35
chr19_+_19779589 0.07 ENST00000541458.1
zinc finger protein 101
chr1_-_6260896 0.07 ENST00000497965.1
ribosomal protein L22
chr1_+_89829610 0.07 ENST00000370456.4
ENST00000535065.1
guanylate binding protein family, member 6
chr12_-_111180644 0.07 ENST00000551676.1
ENST00000550991.1
ENST00000335007.5
ENST00000340766.5
protein phosphatase 1, catalytic subunit, gamma isozyme
chr19_-_44952635 0.07 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
zinc finger protein 229
chr9_+_17135016 0.07 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
centlein, centrosomal protein
chr11_+_19138670 0.07 ENST00000446113.2
ENST00000399351.3
zinc finger, DHHC-type containing 13
chr22_-_42342733 0.07 ENST00000402420.1
centromere protein M
chr14_-_74025625 0.07 ENST00000553558.1
ENST00000563329.1
ENST00000334988.2
ENST00000560393.1
HEAT repeat containing 4
chr2_+_179184955 0.07 ENST00000315022.2
oxysterol binding protein-like 6
chr11_+_107799118 0.07 ENST00000320578.2
RAB39A, member RAS oncogene family
chr2_-_136743169 0.07 ENST00000264161.4
aspartyl-tRNA synthetase
chr19_-_39523165 0.07 ENST00000509137.2
ENST00000292853.4
F-box protein 27
chr18_-_48723129 0.07 ENST00000592416.1
mex-3 RNA binding family member C
chr7_+_16700806 0.07 ENST00000446596.1
ENST00000438834.1
basic leucine zipper and W2 domains 2
chr12_-_15104040 0.07 ENST00000541644.1
ENST00000545895.1
Rho GDP dissociation inhibitor (GDI) beta
chr7_+_99102267 0.07 ENST00000326775.5
ENST00000451158.1
zinc finger with KRAB and SCAN domains 5
chr12_+_124155652 0.07 ENST00000426174.2
ENST00000303372.5
tectonic family member 2
chr11_-_92931098 0.07 ENST00000326402.4
solute carrier family 36 (proton/amino acid symporter), member 4
chr1_-_46598371 0.07 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr5_-_102898465 0.07 ENST00000507423.1
ENST00000230792.2
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr15_+_89922345 0.07 ENST00000558982.1
long intergenic non-protein coding RNA 925
chr6_-_84937314 0.07 ENST00000257766.4
ENST00000403245.3
KIAA1009
chr13_+_98628886 0.07 ENST00000490680.1
ENST00000539640.1
ENST00000403772.3
importin 5
chr1_+_19967014 0.07 ENST00000428975.1
neuroblastoma 1, DAN family BMP antagonist
chr1_+_201708992 0.07 ENST00000367295.1
neuron navigator 1
chr11_-_85779971 0.06 ENST00000393346.3
phosphatidylinositol binding clathrin assembly protein
chr14_-_23446900 0.06 ENST00000556731.1
ajuba LIM protein
chr12_+_19358228 0.06 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr5_-_131132614 0.06 ENST00000307968.7
ENST00000307954.8
folliculin interacting protein 1
chr11_+_28129795 0.06 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
methyltransferase like 15
chr17_+_35849937 0.06 ENST00000394389.4
dual specificity phosphatase 14
chr1_+_100111580 0.06 ENST00000605497.1
palmdelphin
chr4_-_2243839 0.06 ENST00000511885.2
ENST00000506763.1
ENST00000514395.1
ENST00000502440.1
ENST00000243706.4
ENST00000443786.2
polymerase (DNA directed) nu
HAUS augmin-like complex, subunit 3
chr6_-_34639733 0.06 ENST00000374021.1
chromosome 6 open reading frame 106
chr4_-_185303418 0.06 ENST00000610223.1
ENST00000608785.1
RP11-290F5.1
chr20_+_816695 0.06 ENST00000246100.3
family with sequence similarity 110, member A
chr17_+_19314432 0.06 ENST00000575165.2
ring finger protein 112
chr5_-_145562147 0.06 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
leucyl-tRNA synthetase
chr11_+_129685707 0.06 ENST00000281441.3
transmembrane protein 45B
chr9_-_103115135 0.06 ENST00000537512.1
testis expressed 10
chr12_+_56660633 0.06 ENST00000308197.5
coenzyme Q10 homolog A (S. cerevisiae)
chr2_+_219247021 0.06 ENST00000539932.1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr15_+_67547113 0.06 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQ motif containing H
chr3_+_112709804 0.06 ENST00000383677.3
GTP-binding protein 8 (putative)
chr2_-_103353277 0.06 ENST00000258436.5
major facilitator superfamily domain containing 9
chr4_+_26322185 0.06 ENST00000361572.6
recombination signal binding protein for immunoglobulin kappa J region
chr5_-_55290773 0.06 ENST00000502326.3
ENST00000381298.2
interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr2_-_39664405 0.06 ENST00000341681.5
ENST00000263881.3
mitogen-activated protein kinase kinase kinase kinase 3
chr6_-_26124138 0.06 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chr20_-_271304 0.06 ENST00000400269.3
ENST00000360321.2
chromosome 20 open reading frame 96
chr20_+_25388293 0.06 ENST00000262460.4
ENST00000429262.2
GINS complex subunit 1 (Psf1 homolog)
chr17_+_28804380 0.05 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
golgi SNAP receptor complex member 1
chr15_-_90294523 0.05 ENST00000300057.4
mesoderm posterior 1 homolog (mouse)
chr9_+_123837141 0.05 ENST00000373865.2
centriolin
chr3_+_137728842 0.05 ENST00000183605.5
claudin 18
chr19_-_40772221 0.05 ENST00000441941.2
ENST00000580747.1
v-akt murine thymoma viral oncogene homolog 2
chrX_+_16804544 0.05 ENST00000380122.5
ENST00000398155.4
taxilin gamma
chr7_+_17414360 0.05 ENST00000419463.1
AC019117.1
chr9_+_131452239 0.05 ENST00000372688.4
ENST00000372686.5
SET nuclear oncogene

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.3 GO:0090340 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.1 0.6 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.0 0.1 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.2 GO:0003163 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921)
0.0 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0060971 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 0.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.2 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0051586 peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:0070839 divalent metal ion export(GO:0070839)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.0 GO:1903371 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.1 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:1903764 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.0 0.1 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.5 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.0 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1 0.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.0 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA