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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX4

Z-value: 1.01

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Transcription factors associated with TBX4

Gene Symbol Gene ID Gene Info
TBX4
ENSG00000121075.5 T-box transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX4hg19_v2_chr17_+_59529743_595297980.157.7e-01Click!

Activity profile of TBX4 motif

Sorted Z-values of TBX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_75746664 0.62 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr7_+_107220899 0.61 ENST00000379117.2
ENST00000473124.1
BCAP29
B-cell receptor-associated protein 29
chr9_+_40028620 0.55 ENST00000426179.1
AL353791.1
AL353791.1
chr11_+_73358594 0.44 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr1_+_154378049 0.43 ENST00000512471.1
IL6R
interleukin 6 receptor
chr10_-_16563870 0.42 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr2_-_85895295 0.40 ENST00000428225.1
ENST00000519937.2
SFTPB
surfactant protein B
chr9_-_75567962 0.39 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr11_+_86511569 0.39 ENST00000441050.1
PRSS23
protease, serine, 23
chr1_+_154377669 0.38 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr11_+_86511549 0.36 ENST00000533902.2
PRSS23
protease, serine, 23
chr8_+_73449625 0.36 ENST00000523207.1
KCNB2
potassium voltage-gated channel, Shab-related subfamily, member 2
chr15_+_36994210 0.35 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr16_-_2205352 0.35 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr2_-_111291587 0.34 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr8_-_99954788 0.32 ENST00000523601.1
STK3
serine/threonine kinase 3
chr2_+_219472637 0.32 ENST00000417849.1
PLCD4
phospholipase C, delta 4
chr11_-_85430204 0.31 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr11_+_122709200 0.30 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr2_+_219472488 0.30 ENST00000450993.2
PLCD4
phospholipase C, delta 4
chr11_+_111749650 0.28 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chr4_-_186732048 0.28 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr11_+_111750206 0.28 ENST00000530214.1
ENST00000530799.1
C11orf1
chromosome 11 open reading frame 1
chr11_-_85430356 0.27 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr11_-_125932685 0.27 ENST00000527967.1
CDON
cell adhesion associated, oncogene regulated
chr7_-_105319536 0.26 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr20_+_44098385 0.26 ENST00000217425.5
ENST00000339946.3
WFDC2
WAP four-disulfide core domain 2
chr10_+_7860460 0.26 ENST00000344293.5
TAF3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
chr11_-_85430088 0.25 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr2_+_29033682 0.24 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
SPDYA
speedy/RINGO cell cycle regulator family member A
chr22_-_42342733 0.24 ENST00000402420.1
CENPM
centromere protein M
chr15_+_41913690 0.23 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr11_-_111749767 0.23 ENST00000542429.1
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr4_+_102268904 0.21 ENST00000527564.1
ENST00000529296.1
AP001816.1
Uncharacterized protein
chr1_+_206680879 0.21 ENST00000355294.4
ENST00000367117.3
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr14_+_53196872 0.21 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr7_+_107220660 0.20 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr11_-_34535332 0.20 ENST00000257832.2
ENST00000429939.2
ELF5
E74-like factor 5 (ets domain transcription factor)
chr3_-_93747425 0.20 ENST00000315099.2
STX19
syntaxin 19
chr11_-_85430163 0.19 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr11_-_85779971 0.18 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr11_-_133826852 0.18 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr3_+_107364769 0.18 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr17_-_37557846 0.18 ENST00000394294.3
ENST00000583610.1
ENST00000264658.6
FBXL20
F-box and leucine-rich repeat protein 20
chr13_+_115047097 0.18 ENST00000351487.5
UPF3A
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr14_-_45603657 0.17 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr12_+_57853918 0.17 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1
GLI family zinc finger 1
chr4_-_102268484 0.16 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr11_-_5248294 0.16 ENST00000335295.4
HBB
hemoglobin, beta
chr3_-_49459865 0.16 ENST00000427987.1
AMT
aminomethyltransferase
chr6_+_79577189 0.16 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr16_+_67596310 0.16 ENST00000264010.4
ENST00000401394.1
CTCF
CCCTC-binding factor (zinc finger protein)
chr15_-_90294523 0.16 ENST00000300057.4
MESP1
mesoderm posterior 1 homolog (mouse)
chr14_-_65569244 0.16 ENST00000557277.1
ENST00000556892.1
MAX
MYC associated factor X
chr9_+_71986182 0.15 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr9_+_127023704 0.15 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr2_-_175870085 0.15 ENST00000409156.3
CHN1
chimerin 1
chr2_-_175869936 0.15 ENST00000409900.3
CHN1
chimerin 1
chr10_+_135050908 0.15 ENST00000325980.9
VENTX
VENT homeobox
chr3_+_142315225 0.15 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr7_-_28220354 0.15 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr14_+_75746781 0.15 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr11_-_114271139 0.15 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr3_-_49459878 0.14 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT
aminomethyltransferase
chr4_-_114682936 0.13 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr8_+_123793633 0.13 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr17_-_39222131 0.13 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr2_+_61108771 0.13 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr4_-_114682597 0.13 ENST00000394524.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr2_+_62932779 0.13 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
EHBP1
EH domain binding protein 1
chr5_+_74807886 0.13 ENST00000514296.1
POLK
polymerase (DNA directed) kappa
chr8_-_101724989 0.12 ENST00000517403.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr3_+_107364683 0.12 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr15_-_83474806 0.12 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr11_+_18343800 0.12 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr2_-_61697862 0.12 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr8_-_95907423 0.12 ENST00000396133.3
ENST00000308108.4
CCNE2
cyclin E2
chr16_+_2588012 0.12 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr20_+_44098346 0.11 ENST00000372676.3
WFDC2
WAP four-disulfide core domain 2
chr1_+_27113963 0.11 ENST00000430292.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr11_+_18344106 0.11 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr4_-_102268708 0.11 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chrX_+_123095860 0.11 ENST00000428941.1
STAG2
stromal antigen 2
chr5_-_74807418 0.11 ENST00000405807.4
ENST00000261415.7
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr16_+_57139933 0.11 ENST00000566259.1
CPNE2
copine II
chr12_-_18890940 0.11 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1
phospholipase C, zeta 1
chr11_+_111749942 0.10 ENST00000260276.3
C11orf1
chromosome 11 open reading frame 1
chr9_-_74979420 0.10 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr6_+_7541808 0.10 ENST00000379802.3
DSP
desmoplakin
chr11_+_1940786 0.10 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
TNNT3
troponin T type 3 (skeletal, fast)
chrX_+_46772065 0.10 ENST00000455411.1
PHF16
jade family PHD finger 3
chr3_-_66551397 0.09 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr14_+_85994943 0.09 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr11_+_114271251 0.09 ENST00000375490.5
RBM7
RNA binding motif protein 7
chr22_-_41215291 0.09 ENST00000542412.1
ENST00000544408.1
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr8_+_87111059 0.09 ENST00000285393.3
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr11_-_34535297 0.09 ENST00000532417.1
ELF5
E74-like factor 5 (ets domain transcription factor)
chr1_+_151584544 0.09 ENST00000458013.2
ENST00000368843.3
SNX27
sorting nexin family member 27
chrX_+_123095890 0.09 ENST00000435215.1
STAG2
stromal antigen 2
chr5_+_110407390 0.09 ENST00000344895.3
TSLP
thymic stromal lymphopoietin
chr2_+_61108650 0.09 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr11_+_114270752 0.08 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr10_+_31608054 0.08 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr2_+_62933001 0.08 ENST00000263991.5
ENST00000354487.3
EHBP1
EH domain binding protein 1
chr7_-_76255444 0.08 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr12_-_120241187 0.08 ENST00000392520.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr2_+_103089756 0.08 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr5_+_82767284 0.08 ENST00000265077.3
VCAN
versican
chr6_-_31080336 0.08 ENST00000259870.3
C6orf15
chromosome 6 open reading frame 15
chr1_+_95582881 0.08 ENST00000370203.4
ENST00000456991.1
TMEM56
transmembrane protein 56
chr3_+_137728842 0.08 ENST00000183605.5
CLDN18
claudin 18
chr6_+_167536230 0.08 ENST00000341935.5
ENST00000349984.4
CCR6
chemokine (C-C motif) receptor 6
chr1_+_114471972 0.08 ENST00000369559.4
ENST00000369554.2
HIPK1
homeodomain interacting protein kinase 1
chr14_+_90864504 0.08 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr4_+_140222609 0.08 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr11_-_74660065 0.08 ENST00000525407.1
ENST00000528219.1
ENST00000531852.1
XRRA1
X-ray radiation resistance associated 1
chr13_-_52027134 0.08 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chrX_+_46771848 0.07 ENST00000218343.4
PHF16
jade family PHD finger 3
chr16_+_2587965 0.07 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chrX_+_123095546 0.07 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr17_-_26220366 0.07 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr4_-_146859787 0.07 ENST00000508784.1
ZNF827
zinc finger protein 827
chr17_+_30771279 0.07 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr20_+_11898507 0.07 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr22_+_40441456 0.07 ENST00000402203.1
TNRC6B
trinucleotide repeat containing 6B
chr2_-_37458749 0.07 ENST00000234170.5
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta
chr10_-_98945264 0.07 ENST00000314867.5
SLIT1
slit homolog 1 (Drosophila)
chr17_+_79031415 0.07 ENST00000572073.1
ENST00000573677.1
BAIAP2
BAI1-associated protein 2
chr17_+_35849937 0.06 ENST00000394389.4
DUSP14
dual specificity phosphatase 14
chr18_-_53068911 0.06 ENST00000537856.3
TCF4
transcription factor 4
chr3_-_66551351 0.06 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr4_-_140222358 0.06 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr11_-_111749878 0.06 ENST00000260257.4
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr7_+_133261209 0.06 ENST00000545148.1
EXOC4
exocyst complex component 4
chr5_+_32712363 0.06 ENST00000507141.1
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr13_-_46543805 0.06 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr4_-_102268628 0.06 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr2_-_160473114 0.06 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr5_-_78809950 0.06 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr3_-_133748913 0.05 ENST00000310926.4
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr12_+_50451331 0.05 ENST00000228468.4
ASIC1
acid-sensing (proton-gated) ion channel 1
chrX_+_123480194 0.05 ENST00000371139.4
SH2D1A
SH2 domain containing 1A
chr2_-_219925189 0.05 ENST00000295731.6
IHH
indian hedgehog
chr6_+_39760129 0.05 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr7_-_150675372 0.05 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr5_+_74807581 0.05 ENST00000241436.4
ENST00000352007.5
POLK
polymerase (DNA directed) kappa
chr12_-_53097247 0.05 ENST00000341809.3
ENST00000537195.1
KRT77
keratin 77
chr1_-_11907829 0.05 ENST00000376480.3
NPPA
natriuretic peptide A
chr2_+_17997763 0.05 ENST00000281047.3
MSGN1
mesogenin 1
chr5_+_56469843 0.05 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr5_+_68788594 0.05 ENST00000396442.2
ENST00000380766.2
OCLN
occludin
chr11_+_74660278 0.05 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chrX_+_70443050 0.04 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr11_+_4116054 0.04 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr16_+_2587998 0.04 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr2_+_43864387 0.04 ENST00000282406.4
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr1_+_172628154 0.04 ENST00000340030.3
ENST00000367721.2
FASLG
Fas ligand (TNF superfamily, member 6)
chr7_+_143013198 0.04 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr21_+_30502806 0.03 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr5_+_82767487 0.03 ENST00000343200.5
ENST00000342785.4
VCAN
versican
chr12_+_104324112 0.03 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr3_-_133748758 0.03 ENST00000493729.1
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr10_-_99531709 0.03 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr5_+_56469939 0.03 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr22_-_41215328 0.03 ENST00000434185.1
ENST00000435456.2
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr17_-_8066843 0.03 ENST00000404970.3
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr17_-_39203519 0.03 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr21_+_30503282 0.03 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr3_-_197024394 0.03 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr5_+_60240943 0.03 ENST00000296597.5
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr5_+_125800836 0.03 ENST00000511134.1
GRAMD3
GRAM domain containing 3
chr15_+_90319557 0.02 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr5_+_56469775 0.02 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr5_-_88180342 0.02 ENST00000502983.1
MEF2C
myocyte enhancer factor 2C
chrX_+_16804544 0.02 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr1_+_27114589 0.02 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr18_-_53068782 0.02 ENST00000569012.1
TCF4
transcription factor 4
chrM_+_10464 0.02 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr17_-_61996160 0.02 ENST00000458650.2
ENST00000351388.4
ENST00000323322.5
GH1
growth hormone 1
chr15_-_58357932 0.02 ENST00000347587.3
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr1_+_27114418 0.02 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr13_-_103053946 0.02 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr4_-_114438763 0.02 ENST00000509594.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr1_+_114471809 0.01 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chr10_-_75226166 0.01 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr17_-_61996136 0.01 ENST00000342364.4
GH1
growth hormone 1
chrX_+_47050798 0.01 ENST00000412206.1
ENST00000427561.1
UBA1
ubiquitin-like modifier activating enzyme 1
chr2_+_219081817 0.01 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr20_+_44657845 0.01 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr11_-_62689046 0.01 ENST00000306960.3
ENST00000543973.1
CHRM1
cholinergic receptor, muscarinic 1
chr18_-_53068940 0.01 ENST00000562638.1
TCF4
transcription factor 4
chr12_-_90024360 0.01 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chrX_+_56259316 0.01 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr16_+_85645007 0.01 ENST00000405402.2
GSE1
Gse1 coiled-coil protein
chr4_-_114682719 0.01 ENST00000394522.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr5_+_60241020 0.00 ENST00000511107.1
ENST00000502658.1
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr15_-_44092295 0.00 ENST00000249714.3
ENST00000299969.6
ENST00000319327.6
SERINC4
serine incorporator 4
chr14_+_93897199 0.00 ENST00000553484.1
UNC79
unc-79 homolog (C. elegans)
chr9_+_140032842 0.00 ENST00000371561.3
ENST00000315048.3
GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.3 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.1 0.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.8 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 1.0 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.4 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.2 GO:0090381 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of mesodermal cell fate specification(GO:0042662) cardiac cell fate determination(GO:0060913) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012) negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.3 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0043132 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:0032474 otolith morphogenesis(GO:0032474) otolith development(GO:0048840)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.2 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.3 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.3 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.0 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.6 GO:0035976 AP1 complex(GO:0035976)
0.1 0.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.4 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.2 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.3 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor