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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TCF7L1

Z-value: 0.49

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Transcription factors associated with TCF7L1

Gene Symbol Gene ID Gene Info
TCF7L1
ENSG00000152284.4 transcription factor 7 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L1hg19_v2_chr2_+_85360499_853605980.522.9e-01Click!

Activity profile of TCF7L1 motif

Sorted Z-values of TCF7L1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_55466915 0.46 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr8_-_11660077 0.36 ENST00000533405.1
RP11-297N6.4
Uncharacterized protein
chr13_-_30160925 0.28 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr2_-_241835561 0.28 ENST00000388934.4
C2orf54
chromosome 2 open reading frame 54
chr1_-_200992827 0.25 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr8_+_55467072 0.24 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr2_+_228678550 0.22 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr7_-_105926058 0.22 ENST00000417537.1
NAMPT
nicotinamide phosphoribosyltransferase
chr1_-_219615984 0.20 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr19_-_18717627 0.19 ENST00000392386.3
CRLF1
cytokine receptor-like factor 1
chr17_+_72428266 0.18 ENST00000582473.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr12_-_130529501 0.18 ENST00000561864.1
ENST00000567788.1
RP11-474D1.4
RP11-474D1.3
RP11-474D1.4
RP11-474D1.3
chr6_+_43968306 0.17 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr5_-_175964366 0.16 ENST00000274811.4
RNF44
ring finger protein 44
chr14_+_101293687 0.16 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr19_-_59030921 0.16 ENST00000354590.3
ENST00000596739.1
ZBTB45
zinc finger and BTB domain containing 45
chr19_-_59031118 0.16 ENST00000600990.1
ZBTB45
zinc finger and BTB domain containing 45
chr12_+_70760056 0.15 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr12_-_133464118 0.15 ENST00000540963.1
CHFR
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr8_-_95220775 0.15 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr17_+_7533439 0.14 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr8_-_145047688 0.14 ENST00000356346.3
PLEC
plectin
chr9_+_97766469 0.14 ENST00000433691.2
C9orf3
chromosome 9 open reading frame 3
chr15_+_43885799 0.14 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr4_-_186877481 0.13 ENST00000444781.1
ENST00000432655.1
SORBS2
sorbin and SH3 domain containing 2
chr15_-_82338460 0.13 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr10_+_71562180 0.13 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr14_+_62331592 0.13 ENST00000554436.1
CTD-2277K2.1
CTD-2277K2.1
chr4_-_109090106 0.13 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chr10_+_71561630 0.13 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr3_-_134093395 0.12 ENST00000249883.5
AMOTL2
angiomotin like 2
chr4_-_109089573 0.12 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr12_-_108154705 0.12 ENST00000547188.1
PRDM4
PR domain containing 4
chr11_-_76155618 0.12 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr4_-_146859623 0.12 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827
chr6_-_29527702 0.12 ENST00000377050.4
UBD
ubiquitin D
chr17_+_30813576 0.12 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr4_-_140477910 0.12 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr15_+_96897466 0.11 ENST00000558382.1
ENST00000558499.1
RP11-522B15.3
RP11-522B15.3
chr4_-_120243545 0.11 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr14_+_75230011 0.11 ENST00000552421.1
ENST00000325680.7
ENST00000238571.3
YLPM1
YLP motif containing 1
chr8_-_33424636 0.11 ENST00000256257.1
RNF122
ring finger protein 122
chr8_+_32579321 0.11 ENST00000522402.1
NRG1
neuregulin 1
chr20_+_44509857 0.11 ENST00000372523.1
ENST00000372520.1
ZSWIM1
zinc finger, SWIM-type containing 1
chr5_-_157002775 0.11 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr5_+_66300464 0.11 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr2_+_11679963 0.11 ENST00000263834.5
GREB1
growth regulation by estrogen in breast cancer 1
chr5_+_66124590 0.11 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr7_+_73245193 0.10 ENST00000340958.2
CLDN4
claudin 4
chr17_+_80416482 0.10 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
NARF
nuclear prelamin A recognition factor
chrX_+_125953746 0.10 ENST00000371125.3
CXorf64
chromosome X open reading frame 64
chr7_+_80275953 0.10 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr4_-_70626314 0.10 ENST00000510821.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr1_+_8378140 0.10 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr19_+_11071652 0.10 ENST00000344626.4
ENST00000429416.3
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr12_-_49582593 0.10 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr4_+_79567057 0.10 ENST00000503259.1
ENST00000507802.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr8_+_32579341 0.10 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr16_+_19222479 0.10 ENST00000568433.1
SYT17
synaptotagmin XVII
chr17_-_46035187 0.10 ENST00000300557.2
PRR15L
proline rich 15-like
chr8_-_119964434 0.10 ENST00000297350.4
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr11_-_62474803 0.10 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr12_-_49453557 0.10 ENST00000547610.1
KMT2D
lysine (K)-specific methyltransferase 2D
chr19_-_2328572 0.09 ENST00000252622.10
LSM7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_+_65339820 0.09 ENST00000316409.2
ENST00000449319.2
ENST00000530349.1
FAM89B
family with sequence similarity 89, member B
chr17_+_79679299 0.09 ENST00000331531.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr17_+_9066252 0.09 ENST00000436734.1
NTN1
netrin 1
chr17_-_39093672 0.09 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr12_+_9066472 0.09 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr8_+_11660227 0.09 ENST00000443614.2
ENST00000525900.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr5_+_131593364 0.09 ENST00000253754.3
ENST00000379018.3
PDLIM4
PDZ and LIM domain 4
chr19_+_41256764 0.09 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr19_+_11071546 0.08 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr1_-_32801825 0.08 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr15_+_75074410 0.08 ENST00000439220.2
CSK
c-src tyrosine kinase
chr17_-_7297833 0.08 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr4_-_5894777 0.08 ENST00000324989.7
CRMP1
collapsin response mediator protein 1
chr5_+_133450365 0.08 ENST00000342854.5
ENST00000321603.6
ENST00000321584.4
ENST00000378564.1
ENST00000395029.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr8_+_11660120 0.08 ENST00000220584.4
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr2_-_97534312 0.08 ENST00000442264.1
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr19_-_7990991 0.08 ENST00000318978.4
CTXN1
cortexin 1
chr12_-_49582978 0.08 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr16_-_89007491 0.08 ENST00000327483.5
ENST00000564416.1
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr10_+_71561649 0.08 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chr14_+_59100774 0.08 ENST00000556859.1
ENST00000421793.1
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr1_+_53793885 0.08 ENST00000445039.2
RP4-784A16.5
RP4-784A16.5
chr3_-_148939598 0.08 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr1_-_1334685 0.07 ENST00000400809.3
ENST00000408918.4
CCNL2
cyclin L2
chr7_+_80275752 0.07 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr19_-_40791302 0.07 ENST00000392038.2
ENST00000578123.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr5_+_170846640 0.07 ENST00000274625.5
FGF18
fibroblast growth factor 18
chr13_+_96743093 0.07 ENST00000376705.2
HS6ST3
heparan sulfate 6-O-sulfotransferase 3
chrX_+_46937745 0.07 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
RGN
regucalcin
chr12_-_49582837 0.07 ENST00000547939.1
ENST00000546918.1
ENST00000552924.1
TUBA1A
tubulin, alpha 1a
chr20_+_30555805 0.07 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr12_-_108154925 0.07 ENST00000228437.5
PRDM4
PR domain containing 4
chr7_+_80275621 0.07 ENST00000426978.1
ENST00000432207.1
CD36
CD36 molecule (thrombospondin receptor)
chr10_-_101380121 0.07 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr15_+_75074915 0.07 ENST00000567123.1
ENST00000569462.1
CSK
c-src tyrosine kinase
chr1_+_61330931 0.07 ENST00000371191.1
NFIA
nuclear factor I/A
chr14_-_20922960 0.07 ENST00000553640.1
ENST00000488532.2
OSGEP
O-sialoglycoprotein endopeptidase
chr4_+_79567314 0.07 ENST00000503539.1
ENST00000504675.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr1_+_36348790 0.07 ENST00000373204.4
AGO1
argonaute RISC catalytic component 1
chr22_+_41347363 0.07 ENST00000216225.8
RBX1
ring-box 1, E3 ubiquitin protein ligase
chr21_+_18811205 0.06 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chr19_-_40791211 0.06 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chrX_-_135962923 0.06 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr3_-_134093275 0.06 ENST00000513145.1
ENST00000422605.2
AMOTL2
angiomotin like 2
chr16_-_73082274 0.06 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr15_+_90744745 0.06 ENST00000558051.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr12_+_9067123 0.06 ENST00000543824.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chrX_+_69488174 0.06 ENST00000480877.2
ENST00000307959.8
ARR3
arrestin 3, retinal (X-arrestin)
chr5_-_157002749 0.06 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM19
ADAM metallopeptidase domain 19
chr10_+_11207088 0.06 ENST00000608830.1
CELF2
CUGBP, Elav-like family member 2
chr9_-_34381536 0.06 ENST00000379126.3
ENST00000379127.1
ENST00000379133.3
C9orf24
chromosome 9 open reading frame 24
chr9_+_139221880 0.06 ENST00000392945.3
ENST00000440944.1
GPSM1
G-protein signaling modulator 1
chr11_-_65381643 0.06 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr17_+_80416050 0.06 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
NARF
nuclear prelamin A recognition factor
chr17_-_38020392 0.06 ENST00000346872.3
ENST00000439167.2
ENST00000377945.3
ENST00000394189.2
ENST00000377944.3
ENST00000377958.2
ENST00000535189.1
ENST00000377952.2
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr10_-_45803286 0.06 ENST00000536058.1
OR13A1
olfactory receptor, family 13, subfamily A, member 1
chr18_+_3449821 0.06 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr10_+_7745303 0.06 ENST00000429820.1
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr12_-_49449107 0.06 ENST00000301067.7
KMT2D
lysine (K)-specific methyltransferase 2D
chr1_+_144339738 0.05 ENST00000538264.1
AL592284.1
Protein LOC642441
chr13_-_72440901 0.05 ENST00000359684.2
DACH1
dachshund homolog 1 (Drosophila)
chr17_-_56065484 0.05 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr17_-_7297519 0.05 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chrX_-_110655391 0.05 ENST00000356915.2
ENST00000356220.3
DCX
doublecortin
chr3_+_189349162 0.05 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr5_+_66300446 0.05 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr17_-_61819229 0.05 ENST00000447001.3
ENST00000392950.4
STRADA
STE20-related kinase adaptor alpha
chr7_+_150076406 0.05 ENST00000329630.5
ZNF775
zinc finger protein 775
chr14_+_105941118 0.05 ENST00000550577.1
ENST00000538259.2
CRIP2
cysteine-rich protein 2
chr6_-_32145861 0.05 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr14_-_65409502 0.05 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr9_+_75263565 0.05 ENST00000396237.3
TMC1
transmembrane channel-like 1
chr12_-_109797249 0.05 ENST00000538041.1
RP11-256L11.1
RP11-256L11.1
chr8_+_55471630 0.05 ENST00000522001.1
RP11-53M11.3
RP11-53M11.3
chr8_-_42234745 0.05 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr7_+_80275663 0.05 ENST00000413265.1
CD36
CD36 molecule (thrombospondin receptor)
chr15_-_65670360 0.05 ENST00000327987.4
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chrX_+_69488155 0.05 ENST00000374495.3
ARR3
arrestin 3, retinal (X-arrestin)
chr20_+_55966444 0.05 ENST00000356208.5
ENST00000440234.2
RBM38
RNA binding motif protein 38
chr4_+_79567362 0.05 ENST00000512322.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chrX_-_43832711 0.05 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr2_-_208031542 0.05 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_+_32479430 0.05 ENST00000327300.7
ENST00000492989.1
KHDRBS1
KH domain containing, RNA binding, signal transduction associated 1
chr13_-_72441315 0.05 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1
dachshund homolog 1 (Drosophila)
chr10_+_54074033 0.04 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr13_+_24144796 0.04 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr10_+_7745232 0.04 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr16_-_4852915 0.04 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr2_+_47168313 0.04 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
TTC7A
tetratricopeptide repeat domain 7A
chr15_+_65134088 0.04 ENST00000323544.4
ENST00000437723.1
PLEKHO2
AC069368.3
pleckstrin homology domain containing, family O member 2
Uncharacterized protein
chr10_-_104192405 0.04 ENST00000369937.4
CUEDC2
CUE domain containing 2
chr7_-_27213893 0.04 ENST00000283921.4
HOXA10
homeobox A10
chr4_-_103266355 0.04 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr14_+_39644387 0.04 ENST00000553331.1
ENST00000216832.4
PNN
pinin, desmosome associated protein
chr6_+_143929307 0.04 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr7_-_148581251 0.04 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2
enhancer of zeste homolog 2 (Drosophila)
chrX_-_153599578 0.04 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr12_+_80603233 0.04 ENST00000547103.1
ENST00000458043.2
OTOGL
otogelin-like
chr1_+_47799542 0.04 ENST00000471289.2
ENST00000450808.2
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr17_-_38020379 0.04 ENST00000351680.3
ENST00000346243.3
ENST00000350532.3
ENST00000467757.1
ENST00000439016.2
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr17_-_61819121 0.04 ENST00000245865.5
ENST00000375840.4
ENST00000582137.1
ENST00000579549.1
ENST00000582030.1
ENST00000584110.1
ENST00000580288.1
ENST00000336174.6
ENST00000579340.1
ENST00000580338.1
STRADA
STE20-related kinase adaptor alpha
chr12_+_31477250 0.04 ENST00000313737.4
AC024940.1
AC024940.1
chr2_-_100721923 0.04 ENST00000356421.2
AFF3
AF4/FMR2 family, member 3
chr7_+_80231466 0.04 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr19_+_41257084 0.04 ENST00000601393.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr6_-_151712673 0.04 ENST00000325144.4
ZBTB2
zinc finger and BTB domain containing 2
chrX_-_110655306 0.04 ENST00000371993.2
DCX
doublecortin
chr10_+_71561704 0.04 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr5_-_16936340 0.04 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr14_+_20923350 0.04 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr15_+_80696666 0.04 ENST00000303329.4
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr7_+_139528952 0.04 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr1_-_94079648 0.04 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr9_-_23826298 0.04 ENST00000380117.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr17_+_80416609 0.03 ENST00000577410.1
NARF
nuclear prelamin A recognition factor
chr19_+_1249869 0.03 ENST00000591446.2
MIDN
midnolin
chr8_-_142012169 0.03 ENST00000517453.1
PTK2
protein tyrosine kinase 2
chr21_-_46330545 0.03 ENST00000320216.6
ENST00000397852.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_-_38061522 0.03 ENST00000373062.3
GNL2
guanine nucleotide binding protein-like 2 (nucleolar)
chr2_-_166060571 0.03 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr19_-_48048518 0.03 ENST00000595558.1
ENST00000263351.5
ZNF541
zinc finger protein 541
chr6_-_24645956 0.03 ENST00000543707.1
KIAA0319
KIAA0319
chr14_-_23624511 0.03 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr11_-_18063973 0.03 ENST00000528338.1
TPH1
tryptophan hydroxylase 1
chr15_-_79103757 0.03 ENST00000388820.4
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr2_-_128568721 0.03 ENST00000322313.4
ENST00000393006.1
ENST00000409658.3
ENST00000436787.1
WDR33
WD repeat domain 33
chr7_-_148581360 0.03 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr4_+_79567233 0.03 ENST00000514130.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr13_+_24144509 0.03 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr15_+_41136369 0.03 ENST00000563656.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr1_+_182808474 0.03 ENST00000367549.3
DHX9
DEAH (Asp-Glu-Ala-His) box helicase 9
chr1_-_225840747 0.03 ENST00000366843.2
ENST00000366844.3
ENAH
enabled homolog (Drosophila)
chr1_+_16085244 0.03 ENST00000400773.1
FBLIM1
filamin binding LIM protein 1
chr2_+_47168630 0.03 ENST00000263737.6
TTC7A
tetratricopeptide repeat domain 7A
chr6_-_128222103 0.03 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS
thymocyte selection associated
chr3_+_179280668 0.03 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A
actin-like 6A

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.2 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.3 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.1 GO:1903625 negative regulation of sperm motility(GO:1901318) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.0 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.0 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.2 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.1 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.2 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling