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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TFAP2B

Z-value: 1.12

Motif logo

Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
ENSG00000008196.8 transcription factor AP-2 beta

Activity profile of TFAP2B motif

Sorted Z-values of TFAP2B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_7760457 0.82 ENST00000576384.1
LSM domain containing 1
chr19_-_18717627 0.75 ENST00000392386.3
cytokine receptor-like factor 1
chr5_+_131409476 0.74 ENST00000296871.2
colony stimulating factor 2 (granulocyte-macrophage)
chr12_-_89746264 0.65 ENST00000548755.1
dual specificity phosphatase 6
chr7_+_65958693 0.63 ENST00000445681.1
ENST00000452565.1
GS1-124K5.4
chr2_-_132249955 0.62 ENST00000309451.6
mitotic spindle organizing protein 2A
chr19_+_12944722 0.53 ENST00000591495.1
microtubule associated serine/threonine kinase 1
chr19_+_55897699 0.49 ENST00000558131.1
ENST00000558752.1
ENST00000458349.2
ribosomal protein L28
chr19_-_19739321 0.45 ENST00000588461.1
lysophosphatidic acid receptor 2
chr17_-_7760779 0.44 ENST00000335155.5
ENST00000575071.1
LSM domain containing 1
chr2_+_130939827 0.43 ENST00000409255.1
ENST00000455239.1
mitotic spindle organizing protein 2B
chr7_-_100065686 0.42 ENST00000423266.1
ENST00000456330.1
TSC22 domain family, member 4
chr19_+_13228917 0.41 ENST00000586171.1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr11_-_64052111 0.40 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BCL2-associated agonist of cell death
chr9_+_130922537 0.39 ENST00000372994.1
chromosome 9 open reading frame 16
chr22_-_31742218 0.39 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
POZ (BTB) and AT hook containing zinc finger 1
chr19_+_572543 0.39 ENST00000333511.3
ENST00000573216.1
ENST00000353555.4
basigin (Ok blood group)
chr1_+_152881014 0.38 ENST00000368764.3
ENST00000392667.2
involucrin
chr20_-_49639631 0.38 ENST00000424171.1
ENST00000439216.1
ENST00000371571.4
potassium voltage-gated channel, subfamily G, member 1
chr9_+_136325089 0.37 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
calcium channel flower domain containing 1
chr17_-_61777459 0.37 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIM domain containing 2
chr12_-_122238913 0.37 ENST00000537157.1
AC084018.1
chr8_-_145018905 0.37 ENST00000398774.2
plectin
chr16_-_66959429 0.36 ENST00000420652.1
ENST00000299759.6
Ras-related associated with diabetes
chr19_+_41107249 0.36 ENST00000396819.3
latent transforming growth factor beta binding protein 4
chr19_-_55865908 0.34 ENST00000590900.1
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr16_+_88772866 0.34 ENST00000453996.2
ENST00000312060.5
ENST00000378384.3
ENST00000567949.1
ENST00000564921.1
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr22_+_42665742 0.33 ENST00000332965.3
ENST00000415205.1
ENST00000446578.1
Z83851.3
chr20_-_44516256 0.33 ENST00000372519.3
spermatogenesis associated 25
chr20_+_62327996 0.32 ENST00000369996.1
tumor necrosis factor receptor superfamily, member 6b, decoy
chr20_+_44462749 0.32 ENST00000372541.1
sorting nexin family member 21
chr2_-_220408260 0.32 ENST00000373891.2
chondroitin polymerizing factor
chr14_+_65170820 0.31 ENST00000555982.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr1_+_209929446 0.31 ENST00000479796.1
TRAF3 interacting protein 3
chr8_+_142402089 0.30 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
protein tyrosine phosphatase type IVA, member 3
chr12_-_30907822 0.29 ENST00000540436.1
caprin family member 2
chr4_-_1723040 0.29 ENST00000382936.3
ENST00000536901.1
ENST00000303277.2
transmembrane protein 129
chr19_+_50706866 0.28 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
myosin, heavy chain 14, non-muscle
chr16_-_67970990 0.28 ENST00000358514.4
proteasome (prosome, macropain) subunit, beta type, 10
chr22_-_50708781 0.28 ENST00000449719.2
ENST00000330651.6
mitogen-activated protein kinase 11
chr17_+_1627834 0.27 ENST00000419248.1
ENST00000418841.1
WD repeat domain 81
chr17_+_7748233 0.27 ENST00000570632.1
lysine (K)-specific demethylase 6B
chr19_+_19144384 0.27 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr11_+_809647 0.27 ENST00000321153.4
ribosomal protein, large, P2
chr17_-_48133054 0.27 ENST00000499842.1
RP11-1094H24.4
chr2_+_96012397 0.27 ENST00000468529.1
Kv channel interacting protein 3, calsenilin
chr17_-_8093471 0.26 ENST00000389017.4
chromosome 17 open reading frame 59
chr2_-_220408430 0.26 ENST00000243776.6
chondroitin polymerizing factor
chr1_-_1535455 0.26 ENST00000422725.1
chromosome 1 open reading frame 233
chr10_-_35930219 0.26 ENST00000374694.1
frizzled family receptor 8
chr1_-_44497024 0.25 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr16_+_2255710 0.25 ENST00000397124.1
ENST00000565250.1
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr16_+_2255841 0.25 ENST00000301725.7
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr9_-_131534160 0.25 ENST00000291900.2
zyg-11 related, cell cycle regulator
chr17_-_72869140 0.25 ENST00000583917.1
ENST00000293195.5
ENST00000442102.2
ferredoxin reductase
chr17_-_79869340 0.24 ENST00000538936.2
phosphate cytidylyltransferase 2, ethanolamine
chr1_+_155051379 0.24 ENST00000418360.2
ephrin-A3
chr11_+_809961 0.24 ENST00000530797.1
ribosomal protein, large, P2
chr11_-_62379752 0.24 ENST00000466671.1
ENST00000466886.1
echinoderm microtubule associated protein like 3
chr11_+_111169565 0.24 ENST00000528846.1
colorectal cancer associated 2
chr19_-_42758040 0.24 ENST00000593944.1
Ets2 repressor factor
chr14_+_92980111 0.24 ENST00000216487.7
ENST00000557762.1
Ras and Rab interactor 3
chr9_-_131534188 0.23 ENST00000414921.1
zyg-11 related, cell cycle regulator
chr14_+_23341513 0.23 ENST00000546834.1
low density lipoprotein receptor-related protein 10
chr16_-_2827128 0.23 ENST00000494946.2
ENST00000409477.1
ENST00000572954.1
ENST00000262306.7
ENST00000409906.4
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
chrX_-_83442915 0.23 ENST00000262752.2
ENST00000543399.1
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr8_-_70983506 0.23 ENST00000276594.2
PR domain containing 14
chr7_+_76139741 0.23 ENST00000334348.3
ENST00000419923.2
ENST00000448265.3
ENST00000443097.2
uroplakin 3B
chr8_-_145047688 0.22 ENST00000356346.3
plectin
chr15_+_73976715 0.22 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276 molecule
chr1_+_33722080 0.22 ENST00000483388.1
ENST00000539719.1
zinc finger protein 362
chr9_-_139268068 0.22 ENST00000371734.3
ENST00000371732.5
ENST00000315908.7
caspase recruitment domain family, member 9
chr1_-_21948906 0.22 ENST00000374761.2
ENST00000599760.1
RAP1 GTPase activating protein
chr19_+_55897297 0.22 ENST00000431533.2
ENST00000428193.2
ENST00000558815.1
ENST00000560583.1
ENST00000560055.1
ENST00000559463.1
ribosomal protein L28
chr19_+_38397839 0.21 ENST00000222345.6
signal-induced proliferation-associated 1 like 3
chr5_-_134369973 0.21 ENST00000265340.7
paired-like homeodomain 1
chr16_+_30907927 0.21 ENST00000279804.2
ENST00000395019.3
cardiotrophin 1
chr16_+_2867164 0.21 ENST00000455114.1
ENST00000450020.3
protease, serine, 21 (testisin)
chr17_-_17399701 0.21 ENST00000225688.3
ENST00000579152.1
RAS, dexamethasone-induced 1
chr17_-_73874654 0.21 ENST00000254816.2
tripartite motif containing 47
chr17_-_72869086 0.21 ENST00000581530.1
ENST00000420580.2
ENST00000455107.2
ENST00000413947.2
ENST00000581219.1
ENST00000582944.1
ferredoxin reductase
chr3_+_75713481 0.20 ENST00000308062.3
ENST00000464571.1
FSHD region gene 2 family, member C
chr7_-_27142290 0.20 ENST00000222718.5
homeobox A2
chr3_-_158450231 0.20 ENST00000479756.1
retinoic acid receptor responder (tazarotene induced) 1
chr11_+_111169976 0.20 ENST00000398035.2
colorectal cancer associated 2
chr3_-_52090461 0.20 ENST00000296483.6
ENST00000495880.1
dual specificity phosphatase 7
chr11_-_72852320 0.20 ENST00000422375.1
FCH and double SH3 domains 2
chr8_-_144655141 0.19 ENST00000398882.3
maestro heat-like repeat family member 6
chr8_-_2585929 0.19 ENST00000519393.1
ENST00000520842.1
ENST00000520570.1
ENST00000517357.1
ENST00000517984.1
ENST00000523971.1
RP11-134O21.1
chr19_+_45251804 0.19 ENST00000164227.5
B-cell CLL/lymphoma 3
chr19_+_42387228 0.19 ENST00000354532.3
ENST00000599846.1
ENST00000347545.4
Rho guanine nucleotide exchange factor (GEF) 1
chr3_-_138048682 0.19 ENST00000383180.2
NME/NM23 family member 9
chr15_-_74501310 0.19 ENST00000423167.2
ENST00000432245.2
stimulated by retinoic acid 6
chr17_+_79953310 0.19 ENST00000582355.2
alveolar soft part sarcoma chromosome region, candidate 1
chr17_+_4613918 0.19 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
arrestin, beta 2
chr22_-_38484922 0.19 ENST00000428572.1
BAI1-associated protein 2-like 2
chr8_-_11058847 0.18 ENST00000297303.4
ENST00000416569.2
XK, Kell blood group complex subunit-related family, member 6
chr12_+_6493319 0.18 ENST00000536876.1
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr19_+_17858547 0.18 ENST00000600676.1
ENST00000600209.1
ENST00000596309.1
ENST00000598539.1
ENST00000597474.1
ENST00000593385.1
ENST00000598067.1
ENST00000593833.1
FCH domain only 1
chr12_-_48152853 0.18 ENST00000171000.4
Rap guanine nucleotide exchange factor (GEF) 3
chr19_+_40697514 0.18 ENST00000253055.3
mitogen-activated protein kinase kinase kinase 10
chr22_+_50781723 0.18 ENST00000359139.3
ENST00000395741.3
ENST00000395744.3
protein phosphatase 6, regulatory subunit 2
chr19_+_7710774 0.18 ENST00000602355.1
syntaxin binding protein 2
chr21_+_45719921 0.18 ENST00000349048.4
phosphofructokinase, liver
chr16_-_28503080 0.18 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
ceroid-lipofuscinosis, neuronal 3
chr8_-_21988558 0.18 ENST00000312841.8
hair growth associated
chr16_-_30538079 0.18 ENST00000562803.1
zinc finger protein 768
chr3_-_50360192 0.18 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
hyaluronoglucosaminidase 2
chr19_+_17858509 0.18 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCH domain only 1
chr1_-_40782938 0.18 ENST00000372736.3
ENST00000372748.3
collagen, type IX, alpha 2
chr14_+_102196739 0.17 ENST00000556973.1
Uncharacterized protein
chr21_-_45078019 0.17 ENST00000542962.1
heat shock transcription factor 2 binding protein
chr3_+_42544084 0.17 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
vasoactive intestinal peptide receptor 1
chr19_+_45971246 0.17 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FBJ murine osteosarcoma viral oncogene homolog B
chr11_+_65082289 0.17 ENST00000279249.2
CDC42 effector protein (Rho GTPase binding) 2
chr5_+_177540444 0.17 ENST00000274605.5
NEDD4 binding protein 3
chr11_+_810221 0.17 ENST00000530398.1
ribosomal protein, large, P2
chr11_+_64002292 0.17 ENST00000426086.2
vascular endothelial growth factor B
chr1_-_2345236 0.17 ENST00000508384.1
peroxisomal biogenesis factor 10
chrX_-_153744434 0.17 ENST00000369643.1
ENST00000393572.1
family with sequence similarity 3, member A
chr12_+_48152774 0.17 ENST00000549243.1
solute carrier family 48 (heme transporter), member 1
chr19_+_35629702 0.17 ENST00000351325.4
FXYD domain containing ion transport regulator 1
chr11_+_43964055 0.16 ENST00000528572.1
chromosome 11 open reading frame 96
chr9_-_140009130 0.16 ENST00000497375.1
ENST00000371579.2
dipeptidyl-peptidase 7
chr20_-_49639612 0.16 ENST00000396017.3
ENST00000433903.1
potassium voltage-gated channel, subfamily G, member 1
chr12_+_57854274 0.16 ENST00000528432.1
GLI family zinc finger 1
chr3_-_138048653 0.16 ENST00000460099.1
NME/NM23 family member 9
chr8_-_146017736 0.16 ENST00000528957.1
ribosomal protein L8
chr14_+_65171315 0.16 ENST00000394691.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr19_-_19739007 0.16 ENST00000586703.1
ENST00000591042.1
ENST00000407877.3
lysophosphatidic acid receptor 2
chr2_+_45878790 0.16 ENST00000306156.3
protein kinase C, epsilon
chr9_+_116917807 0.16 ENST00000356083.3
collagen, type XXVII, alpha 1
chr1_+_1447517 0.15 ENST00000378756.3
ENST00000378755.5
ATPase family, AAA domain containing 3A
chr10_+_104154229 0.15 ENST00000428099.1
ENST00000369966.3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr16_-_88772761 0.15 ENST00000567844.1
ENST00000312838.4
ring finger protein 166
chr1_+_46269248 0.15 ENST00000361297.2
ENST00000372009.2
microtubule associated serine/threonine kinase 2
chr19_-_42724261 0.15 ENST00000595337.1
death effector domain containing 2
chr3_-_48470838 0.15 ENST00000358459.4
ENST00000358536.4
plexin B1
chr22_-_20255212 0.15 ENST00000416372.1
reticulon 4 receptor
chr15_-_74501360 0.15 ENST00000323940.5
stimulated by retinoic acid 6
chr10_+_103825080 0.15 ENST00000299238.5
Hermansky-Pudlak syndrome 6
chr6_-_33385854 0.15 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr19_+_13229126 0.15 ENST00000292431.4
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr2_+_74741569 0.15 ENST00000233638.7
T-cell leukemia homeobox 2
chr1_+_209929377 0.15 ENST00000400959.3
ENST00000367025.3
TRAF3 interacting protein 3
chr4_-_84030996 0.15 ENST00000411416.2
placenta-specific 8
chr2_-_28113965 0.15 ENST00000302188.3
ribokinase
chr16_+_2285817 0.14 ENST00000564065.1
deoxyribonuclease I-like 2
chr1_-_147245445 0.14 ENST00000430508.1
gap junction protein, alpha 5, 40kDa
chr12_+_110011571 0.14 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
mevalonate kinase
chr1_-_25291475 0.14 ENST00000338888.3
ENST00000399916.1
runt-related transcription factor 3
chr7_+_150076406 0.14 ENST00000329630.5
zinc finger protein 775
chr4_-_1107306 0.14 ENST00000433731.2
ENST00000333673.5
ENST00000382968.5
ring finger protein 212
chr5_-_141338377 0.14 ENST00000510041.1
protocadherin 12
chr16_-_30537839 0.14 ENST00000380412.5
zinc finger protein 768
chr1_-_147245484 0.14 ENST00000271348.2
gap junction protein, alpha 5, 40kDa
chr14_+_65171099 0.14 ENST00000247226.7
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr12_-_122018346 0.14 ENST00000377069.4
lysine (K)-specific demethylase 2B
chr6_+_30294612 0.14 ENST00000440271.1
ENST00000396551.3
ENST00000376656.4
ENST00000540416.1
ENST00000428728.1
ENST00000396548.1
ENST00000428404.1
tripartite motif containing 39
chr7_+_76139925 0.14 ENST00000394849.1
uroplakin 3B
chr11_+_10326612 0.14 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
adrenomedullin
chrX_+_53449805 0.13 ENST00000414955.2
RIB43A domain with coiled-coils 1
chr19_+_47778119 0.13 ENST00000552360.2
proline rich 24
chr12_-_57634475 0.13 ENST00000393825.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr16_+_57126428 0.13 ENST00000290776.8
copine II
chr7_+_76139833 0.13 ENST00000257632.5
uroplakin 3B
chr19_+_42724423 0.13 ENST00000301215.3
ENST00000597945.1
zinc finger protein 526
chr6_+_33378517 0.13 ENST00000428274.1
PHD finger protein 1
chr6_-_31864977 0.13 ENST00000395728.3
ENST00000375528.4
euchromatic histone-lysine N-methyltransferase 2
chrX_-_78622805 0.13 ENST00000373298.2
integral membrane protein 2A
chr17_-_33446735 0.13 ENST00000460118.2
ENST00000335858.7
RAD51 paralog D
chr1_+_156084461 0.13 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
lamin A/C
chr2_-_55459437 0.13 ENST00000401408.1
clathrin heavy chain linker domain containing 1
chr3_-_150481218 0.13 ENST00000482706.1
siah E3 ubiquitin protein ligase 2
chr20_+_61904556 0.13 ENST00000522403.2
ENST00000550188.1
ADP-ribosylation factor GTPase activating protein 1
chr14_+_24422795 0.13 ENST00000313250.5
ENST00000558263.1
ENST00000543741.2
ENST00000421831.1
ENST00000397073.2
ENST00000308178.8
ENST00000382761.3
ENST00000397075.3
ENST00000397074.3
ENST00000559632.1
ENST00000558581.1
dehydrogenase/reductase (SDR family) member 4
chr11_+_63606558 0.13 ENST00000350490.7
ENST00000502399.3
MAP/microtubule affinity-regulating kinase 2
chrX_-_153744507 0.13 ENST00000442929.1
ENST00000426266.1
ENST00000359889.5
ENST00000369641.3
ENST00000447601.2
ENST00000434658.2
family with sequence similarity 3, member A
chr5_-_157002775 0.13 ENST00000257527.4
ADAM metallopeptidase domain 19
chr8_+_134203303 0.13 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
WNT1 inducible signaling pathway protein 1
chr19_+_41119794 0.13 ENST00000593463.1
latent transforming growth factor beta binding protein 4
chr19_+_10828795 0.13 ENST00000389253.4
ENST00000355667.6
ENST00000408974.4
dynamin 2
chr12_-_48152611 0.13 ENST00000389212.3
Rap guanine nucleotide exchange factor (GEF) 3
chr12_+_53693466 0.12 ENST00000267103.5
ENST00000548632.1
chromosome 12 open reading frame 10
chr2_+_178977143 0.12 ENST00000286070.5
RNA binding motif protein 45
chr11_-_417388 0.12 ENST00000332725.3
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr12_+_133067157 0.12 ENST00000261673.6
fibrosin-like 1
chr17_+_34087888 0.12 ENST00000586491.1
ENST00000588628.1
ENST00000285023.4
chromosome 17 open reading frame 50
chr5_+_176730769 0.12 ENST00000303204.4
ENST00000503216.1
PRELI domain containing 1
chr11_-_64014379 0.12 ENST00000309318.3
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr20_-_3154162 0.12 ENST00000360342.3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr5_+_141016508 0.12 ENST00000444782.1
ENST00000521367.1
ENST00000297164.3
RELT-like 2
chr11_-_64013663 0.12 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr7_+_150549565 0.12 ENST00000360937.4
ENST00000416793.2
ENST00000483043.1
amine oxidase, copper containing 1
chr8_-_146017765 0.12 ENST00000532702.1
ENST00000394920.2
ENST00000527914.1
ribosomal protein L8
chr22_+_31199037 0.12 ENST00000424224.1
oxysterol binding protein 2
chr20_-_31124186 0.12 ENST00000375678.3
chromosome 20 open reading frame 112
chr5_+_149980622 0.12 ENST00000394243.1
synaptopodin
chr6_+_30294186 0.12 ENST00000458516.1
tripartite motif containing 39
chr3_+_133524459 0.12 ENST00000484684.1
signal recognition particle receptor, B subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.6 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.3 GO:0003294 pulmonary valve formation(GO:0003193) atrial ventricular junction remodeling(GO:0003294) foramen ovale closure(GO:0035922) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.1 0.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.4 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.4 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.3 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.2 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0060032 notochord regression(GO:0060032)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.1 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 0.1 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.4 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.1 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.0 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:0071504 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.5 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0090678 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.2 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.2 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.0 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.0 GO:0031133 cellular magnesium ion homeostasis(GO:0010961) regulation of axon diameter(GO:0031133)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.0 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.6 GO:0038202 TORC1 signaling(GO:0038202)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.0 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) regulation of metanephric glomerular mesangial cell proliferation(GO:0072301) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.0 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.8 GO:1903146 regulation of mitophagy(GO:1903146)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 1.0 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.3 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.6 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.5 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 0.3 GO:0086076 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.1 0.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.2 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.2 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins