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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for THRB
Z-value: 0.25
Motif logo
Transcription factors associated with THRB
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
THRB
|
ENSG00000151090.13 | thyroid hormone receptor beta |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| THRB | hg19_v2_chr3_-_24207039_24207086 | 0.74 | 9.0e-02 | Click! |
Activity profile of THRB motif
Sorted Z-values of THRB motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_77997785 | 0.12 |
ENST00000478255.1
|
AK5
|
adenylate kinase 5 |
| chr3_+_172361483 | 0.12 |
ENST00000598405.1
|
AC007919.2
|
HCG1787166; PRO1163; Uncharacterized protein |
| chr8_-_131028782 | 0.10 |
ENST00000519020.1
|
FAM49B
|
family with sequence similarity 49, member B |
| chr8_-_100905925 | 0.08 |
ENST00000518171.1
|
COX6C
|
cytochrome c oxidase subunit VIc |
| chr4_+_189321881 | 0.06 |
ENST00000512839.1
ENST00000513313.1 |
LINC01060
|
long intergenic non-protein coding RNA 1060 |
| chr19_-_52643157 | 0.06 |
ENST00000597013.1
ENST00000600228.1 ENST00000596290.1 |
ZNF616
|
zinc finger protein 616 |
| chr8_-_100905363 | 0.06 |
ENST00000524245.1
|
COX6C
|
cytochrome c oxidase subunit VIc |
| chr20_+_3024266 | 0.06 |
ENST00000245983.2
ENST00000359100.2 ENST00000359987.1 |
GNRH2
|
gonadotropin-releasing hormone 2 |
| chr5_+_131746575 | 0.05 |
ENST00000337752.2
ENST00000378947.3 ENST00000407797.1 |
C5orf56
|
chromosome 5 open reading frame 56 |
| chr13_+_27844464 | 0.05 |
ENST00000241463.4
|
RASL11A
|
RAS-like, family 11, member A |
| chr17_-_73840614 | 0.05 |
ENST00000586108.1
|
UNC13D
|
unc-13 homolog D (C. elegans) |
| chrX_+_101854096 | 0.05 |
ENST00000246174.2
ENST00000537008.1 ENST00000541409.1 |
ARMCX5
|
armadillo repeat containing, X-linked 5 |
| chr8_-_100905850 | 0.04 |
ENST00000520271.1
ENST00000522940.1 ENST00000523016.1 ENST00000517682.2 ENST00000297564.2 |
COX6C
|
cytochrome c oxidase subunit VIc |
| chr2_-_9563469 | 0.04 |
ENST00000484735.1
ENST00000456913.2 |
ITGB1BP1
|
integrin beta 1 binding protein 1 |
| chr8_+_22102626 | 0.04 |
ENST00000519237.1
ENST00000397802.4 |
POLR3D
|
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| chr2_-_9563216 | 0.04 |
ENST00000467606.1
ENST00000494563.1 ENST00000460001.1 |
ITGB1BP1
|
integrin beta 1 binding protein 1 |
| chr17_-_73839792 | 0.04 |
ENST00000590762.1
|
UNC13D
|
unc-13 homolog D (C. elegans) |
| chr11_+_73498898 | 0.03 |
ENST00000535529.1
ENST00000497094.2 ENST00000411840.2 ENST00000535277.1 ENST00000398483.3 ENST00000542303.1 |
MRPL48
|
mitochondrial ribosomal protein L48 |
| chr6_+_151042224 | 0.03 |
ENST00000358517.2
|
PLEKHG1
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 1 |
| chr9_+_100069933 | 0.03 |
ENST00000529487.1
|
CCDC180
|
coiled-coil domain containing 180 |
| chr11_+_73498973 | 0.02 |
ENST00000537007.1
|
MRPL48
|
mitochondrial ribosomal protein L48 |
| chr6_+_77484663 | 0.02 |
ENST00000607287.1
|
RP11-354K4.2
|
RP11-354K4.2 |
| chr10_+_123970670 | 0.02 |
ENST00000496913.2
|
TACC2
|
transforming, acidic coiled-coil containing protein 2 |
| chr4_+_114214125 | 0.02 |
ENST00000509550.1
|
ANK2
|
ankyrin 2, neuronal |
| chr8_+_22102611 | 0.02 |
ENST00000306433.4
|
POLR3D
|
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| chr10_+_35456444 | 0.02 |
ENST00000361599.4
|
CREM
|
cAMP responsive element modulator |
| chr12_-_21810726 | 0.02 |
ENST00000396076.1
|
LDHB
|
lactate dehydrogenase B |
| chr20_+_37434329 | 0.02 |
ENST00000299824.1
ENST00000373331.2 |
PPP1R16B
|
protein phosphatase 1, regulatory subunit 16B |
| chr2_-_73869508 | 0.02 |
ENST00000272425.3
|
NAT8
|
N-acetyltransferase 8 (GCN5-related, putative) |
| chr3_+_50606901 | 0.02 |
ENST00000455834.1
|
HEMK1
|
HemK methyltransferase family member 1 |
| chr10_+_62538089 | 0.02 |
ENST00000519078.2
ENST00000395284.3 ENST00000316629.4 |
CDK1
|
cyclin-dependent kinase 1 |
| chr1_-_154164534 | 0.02 |
ENST00000271850.7
ENST00000368530.2 |
TPM3
|
tropomyosin 3 |
| chr2_+_200472779 | 0.02 |
ENST00000427045.1
ENST00000419243.1 |
AC093590.1
|
AC093590.1 |
| chr12_-_21810765 | 0.02 |
ENST00000450584.1
ENST00000350669.1 |
LDHB
|
lactate dehydrogenase B |
| chr11_+_5617858 | 0.01 |
ENST00000380097.3
|
TRIM6
|
tripartite motif containing 6 |
| chr8_+_28174649 | 0.01 |
ENST00000301908.3
|
PNOC
|
prepronociceptin |
| chr16_-_69368774 | 0.01 |
ENST00000562949.1
|
RP11-343C2.12
|
Conserved oligomeric Golgi complex subunit 8 |
| chr11_+_5617976 | 0.01 |
ENST00000445329.1
|
TRIM6
|
tripartite motif containing 6 |
| chr15_-_35838348 | 0.01 |
ENST00000561411.1
ENST00000256538.4 ENST00000440392.2 |
DPH6
|
diphthamine biosynthesis 6 |
| chr1_-_207224307 | 0.01 |
ENST00000315927.4
|
YOD1
|
YOD1 deubiquitinase |
| chr3_+_50606577 | 0.01 |
ENST00000434410.1
ENST00000232854.4 |
HEMK1
|
HemK methyltransferase family member 1 |
| chr17_+_7533439 | 0.01 |
ENST00000441599.2
ENST00000380450.4 ENST00000416273.3 ENST00000575903.1 ENST00000576830.1 ENST00000571153.1 ENST00000575618.1 ENST00000576152.1 |
SHBG
|
sex hormone-binding globulin |
| chr1_-_113498616 | 0.01 |
ENST00000433570.4
ENST00000538576.1 ENST00000458229.1 |
SLC16A1
|
solute carrier family 16 (monocarboxylate transporter), member 1 |
| chr12_+_54378923 | 0.01 |
ENST00000303460.4
|
HOXC10
|
homeobox C10 |
| chr21_-_37914898 | 0.01 |
ENST00000399136.1
|
CLDN14
|
claudin 14 |
| chr15_+_35838446 | 0.01 |
ENST00000559210.1
|
DPH6-AS1
|
DPH6 antisense RNA 1 (head to head) |
| chr15_-_101084446 | 0.00 |
ENST00000538112.2
ENST00000559639.1 ENST00000558884.2 |
CERS3
|
ceramide synthase 3 |
| chr2_-_9563319 | 0.00 |
ENST00000497105.1
ENST00000360635.3 ENST00000359712.3 |
ITGB1BP1
|
integrin beta 1 binding protein 1 |
| chr15_-_101084881 | 0.00 |
ENST00000284382.4
|
CERS3
|
ceramide synthase 3 |
| chr17_-_73840774 | 0.00 |
ENST00000207549.4
|
UNC13D
|
unc-13 homolog D (C. elegans) |
| chr11_+_46366799 | 0.00 |
ENST00000532868.2
|
DGKZ
|
diacylglycerol kinase, zeta |
| chr7_+_102937869 | 0.00 |
ENST00000249269.4
ENST00000428154.1 ENST00000420236.2 |
PMPCB
|
peptidase (mitochondrial processing) beta |
| chr1_-_113498943 | 0.00 |
ENST00000369626.3
|
SLC16A1
|
solute carrier family 16 (monocarboxylate transporter), member 1 |
| chr11_-_18747727 | 0.00 |
ENST00000513874.1
|
IGSF22
|
immunoglobulin superfamily, member 22 |
Network of associatons between targets according to the STRING database.
First level regulatory network of THRB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0006172 | ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) |
| 0.0 | 0.1 | GO:0002432 | granuloma formation(GO:0002432) |
| 0.0 | 0.1 | GO:2000567 | memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0023025 | MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |