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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TLX1_NFIC

Z-value: 1.15

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Transcription factors associated with TLX1_NFIC

Gene Symbol Gene ID Gene Info
TLX1
ENSG00000107807.8 T cell leukemia homeobox 1
NFIC
ENSG00000141905.13 nuclear factor I C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIChg19_v2_chr19_+_3366547_33666190.691.3e-01Click!
TLX1hg19_v2_chr10_+_102891048_1028910780.453.7e-01Click!

Activity profile of TLX1_NFIC motif

Sorted Z-values of TLX1_NFIC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_79086088 2.13 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr7_+_22766766 1.45 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chrX_-_40005865 0.91 ENST00000412952.1
BCOR
BCL6 corepressor
chr8_+_61822605 0.83 ENST00000526936.1
AC022182.1
AC022182.1
chr21_+_17792672 0.78 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr19_-_59010565 0.55 ENST00000594786.1
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr14_-_85996332 0.53 ENST00000380722.1
RP11-497E19.1
RP11-497E19.1
chr6_-_33663474 0.51 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chr1_-_153363452 0.47 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr7_+_143078652 0.47 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr19_+_58111241 0.44 ENST00000597700.1
ENST00000332854.6
ENST00000597864.1
ZNF530
zinc finger protein 530
chr3_+_46742823 0.42 ENST00000326431.3
TMIE
transmembrane inner ear
chr2_+_179317994 0.42 ENST00000375129.4
DFNB59
deafness, autosomal recessive 59
chr21_+_33784957 0.41 ENST00000401402.3
ENST00000382699.3
EVA1C
eva-1 homolog C (C. elegans)
chr7_+_143079000 0.39 ENST00000392910.2
ZYX
zyxin
chr21_+_33784670 0.39 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chr10_-_100174900 0.38 ENST00000370575.4
PYROXD2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr17_+_79369249 0.37 ENST00000574717.2
RP11-1055B8.6
Uncharacterized protein
chr19_+_40871734 0.36 ENST00000359274.5
PLD3
phospholipase D family, member 3
chr19_+_10397648 0.35 ENST00000340992.4
ENST00000393717.2
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr16_+_226658 0.35 ENST00000320868.5
ENST00000397797.1
HBA1
hemoglobin, alpha 1
chr6_+_132129151 0.34 ENST00000360971.2
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr8_-_42065187 0.34 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT
plasminogen activator, tissue
chr9_-_98268883 0.33 ENST00000551630.1
ENST00000548420.1
PTCH1
patched 1
chr13_-_40924439 0.33 ENST00000400432.3
RP11-172E9.2
RP11-172E9.2
chr3_-_131756559 0.32 ENST00000505957.1
CPNE4
copine IV
chr16_+_30751953 0.32 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr12_-_109797249 0.32 ENST00000538041.1
RP11-256L11.1
RP11-256L11.1
chr19_+_10397621 0.31 ENST00000380770.3
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr8_-_42065075 0.31 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
PLAT
plasminogen activator, tissue
chr20_+_48884002 0.31 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr1_-_154178803 0.31 ENST00000368525.3
C1orf189
chromosome 1 open reading frame 189
chr15_+_89182178 0.31 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr16_+_30662085 0.31 ENST00000569864.1
PRR14
proline rich 14
chr6_+_31021973 0.31 ENST00000570223.1
ENST00000566475.1
ENST00000426185.1
HCG22
HLA complex group 22
chr1_+_32674675 0.31 ENST00000409358.1
DCDC2B
doublecortin domain containing 2B
chr20_-_60942361 0.31 ENST00000252999.3
LAMA5
laminin, alpha 5
chr19_+_3708376 0.30 ENST00000539908.2
TJP3
tight junction protein 3
chr19_-_42927251 0.30 ENST00000597001.1
LIPE
lipase, hormone-sensitive
chr17_-_41910505 0.30 ENST00000398389.4
MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr12_-_109025849 0.29 ENST00000228463.6
SELPLG
selectin P ligand
chr19_+_3708338 0.29 ENST00000590545.1
TJP3
tight junction protein 3
chr1_-_200992827 0.29 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr14_-_50999373 0.29 ENST00000554273.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr8_-_145701718 0.28 ENST00000377317.4
FOXH1
forkhead box H1
chr15_+_89182156 0.28 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr9_+_102584128 0.28 ENST00000338488.4
ENST00000395097.2
NR4A3
nuclear receptor subfamily 4, group A, member 3
chr1_+_110453203 0.28 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr10_+_106034637 0.28 ENST00000401888.2
GSTO2
glutathione S-transferase omega 2
chr16_+_75182376 0.28 ENST00000570010.1
ENST00000568079.1
ENST00000464850.1
ENST00000332307.4
ENST00000393430.2
ZFP1
ZFP1 zinc finger protein
chrX_+_27826107 0.28 ENST00000356790.2
MAGEB10
melanoma antigen family B, 10
chr19_+_45312310 0.28 ENST00000589651.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr16_-_67450325 0.27 ENST00000348579.2
ZDHHC1
zinc finger, DHHC-type containing 1
chrX_-_54522558 0.27 ENST00000375135.3
FGD1
FYVE, RhoGEF and PH domain containing 1
chr17_-_74533734 0.27 ENST00000589342.1
CYGB
cytoglobin
chr10_+_102758105 0.26 ENST00000429732.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr1_+_153747746 0.26 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr11_-_66313699 0.26 ENST00000526986.1
ENST00000310442.3
ZDHHC24
zinc finger, DHHC-type containing 24
chr4_-_110723335 0.26 ENST00000394634.2
CFI
complement factor I
chr11_-_65325664 0.25 ENST00000301873.5
LTBP3
latent transforming growth factor beta binding protein 3
chrX_-_102319092 0.25 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr4_-_110723134 0.25 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr2_+_219187871 0.25 ENST00000258362.3
PNKD
paroxysmal nonkinesigenic dyskinesia
chr20_-_60942326 0.25 ENST00000370677.3
ENST00000370692.3
LAMA5
laminin, alpha 5
chr8_+_102064237 0.25 ENST00000514926.1
RP11-302J23.1
RP11-302J23.1
chr9_-_130617029 0.24 ENST00000373203.4
ENG
endoglin
chr2_+_7017796 0.24 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr16_-_2264779 0.24 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr16_-_69385681 0.24 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr3_-_50340996 0.24 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr6_-_53013620 0.24 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr15_+_75487984 0.24 ENST00000563905.1
C15orf39
chromosome 15 open reading frame 39
chr8_-_145331153 0.23 ENST00000377412.4
KM-PA-2
KM-PA-2 protein; Uncharacterized protein
chr17_+_1633755 0.23 ENST00000545662.1
WDR81
WD repeat domain 81
chr18_-_53735601 0.23 ENST00000589754.1
CTD-2008L17.2
CTD-2008L17.2
chr22_+_50639408 0.23 ENST00000380903.2
SELO
Selenoprotein O
chrX_+_46937745 0.23 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
RGN
regucalcin
chr19_+_45312347 0.23 ENST00000270233.6
ENST00000591520.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr17_-_37764128 0.23 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chr22_-_39640756 0.23 ENST00000331163.6
PDGFB
platelet-derived growth factor beta polypeptide
chr7_-_16844611 0.22 ENST00000401412.1
ENST00000419304.2
AGR2
anterior gradient 2
chr7_-_5463175 0.22 ENST00000399537.4
ENST00000430969.1
TNRC18
trinucleotide repeat containing 18
chrX_-_53310791 0.22 ENST00000375365.2
IQSEC2
IQ motif and Sec7 domain 2
chr8_+_104384616 0.22 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr1_+_27153173 0.22 ENST00000374142.4
ZDHHC18
zinc finger, DHHC-type containing 18
chr5_-_1112141 0.22 ENST00000264930.5
SLC12A7
solute carrier family 12 (potassium/chloride transporter), member 7
chr14_-_50999190 0.22 ENST00000557390.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr14_+_73704201 0.22 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr19_-_12946236 0.22 ENST00000589272.1
ENST00000393233.2
RTBDN
retbindin
chr6_-_16761678 0.22 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr19_+_40195101 0.21 ENST00000360675.3
ENST00000601802.1
LGALS14
lectin, galactoside-binding, soluble, 14
chr9_+_34646651 0.21 ENST00000378842.3
GALT
galactose-1-phosphate uridylyltransferase
chr18_-_74728998 0.21 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP
myelin basic protein
chr17_+_7461613 0.21 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr10_+_135160844 0.21 ENST00000423766.1
ENST00000458230.1
PRAP1
proline-rich acidic protein 1
chrX_+_49126294 0.21 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr22_-_31536480 0.21 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr1_+_110453514 0.20 ENST00000369802.3
ENST00000420111.2
CSF1
colony stimulating factor 1 (macrophage)
chr3_+_48264816 0.19 ENST00000296435.2
ENST00000576243.1
CAMP
cathelicidin antimicrobial peptide
chr21_+_46875395 0.19 ENST00000355480.5
COL18A1
collagen, type XVIII, alpha 1
chr3_+_52350335 0.19 ENST00000420323.2
DNAH1
dynein, axonemal, heavy chain 1
chr11_-_111783919 0.19 ENST00000531198.1
ENST00000533879.1
CRYAB
crystallin, alpha B
chr17_-_7082668 0.19 ENST00000573083.1
ENST00000574388.1
ASGR1
asialoglycoprotein receptor 1
chr3_+_38032216 0.19 ENST00000416303.1
VILL
villin-like
chr17_+_7462103 0.19 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr16_+_28996114 0.19 ENST00000395461.3
LAT
linker for activation of T cells
chr1_+_61547405 0.19 ENST00000371189.4
NFIA
nuclear factor I/A
chr11_-_118789613 0.19 ENST00000532899.1
BCL9L
B-cell CLL/lymphoma 9-like
chr21_+_46875424 0.19 ENST00000359759.4
COL18A1
collagen, type XVIII, alpha 1
chr4_-_110723194 0.19 ENST00000394635.3
CFI
complement factor I
chr9_-_130616915 0.18 ENST00000344849.3
ENG
endoglin
chr14_+_105939276 0.18 ENST00000483017.3
CRIP2
cysteine-rich protein 2
chr7_+_150065278 0.18 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr4_-_84255935 0.18 ENST00000513463.1
HPSE
heparanase
chr16_+_30662184 0.17 ENST00000300835.4
PRR14
proline rich 14
chr3_-_53880401 0.17 ENST00000315251.6
CHDH
choline dehydrogenase
chr7_-_16840820 0.17 ENST00000450569.1
AGR2
anterior gradient 2
chr3_-_12200851 0.17 ENST00000287814.4
TIMP4
TIMP metallopeptidase inhibitor 4
chr11_-_65325430 0.17 ENST00000322147.4
LTBP3
latent transforming growth factor beta binding protein 3
chr19_-_40324255 0.17 ENST00000593685.1
ENST00000600611.1
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr14_+_24867992 0.17 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr1_+_113217309 0.17 ENST00000544796.1
ENST00000369644.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr3_+_186915274 0.17 ENST00000312295.4
RTP1
receptor (chemosensory) transporter protein 1
chr6_+_31950150 0.16 ENST00000537134.1
C4A
complement component 4A (Rodgers blood group)
chr21_+_17443521 0.16 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr8_+_24772455 0.16 ENST00000433454.2
NEFM
neurofilament, medium polypeptide
chr1_-_109399682 0.16 ENST00000369995.3
ENST00000370001.3
AKNAD1
AKNA domain containing 1
chr20_-_34025999 0.16 ENST00000374369.3
GDF5
growth differentiation factor 5
chr7_+_143013198 0.16 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr1_-_32264250 0.16 ENST00000528579.1
SPOCD1
SPOC domain containing 1
chr6_-_43595039 0.16 ENST00000307114.7
GTPBP2
GTP binding protein 2
chr21_+_17791648 0.16 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr18_+_43304092 0.16 ENST00000321925.4
ENST00000587601.1
SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr11_+_61717279 0.16 ENST00000378043.4
BEST1
bestrophin 1
chr14_-_76447336 0.15 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr17_-_4806369 0.15 ENST00000293780.4
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
chr15_-_40213080 0.15 ENST00000561100.1
GPR176
G protein-coupled receptor 176
chr11_+_61717336 0.15 ENST00000378042.3
BEST1
bestrophin 1
chrX_-_154688276 0.15 ENST00000369445.2
F8A3
coagulation factor VIII-associated 3
chr19_-_33716750 0.15 ENST00000253188.4
SLC7A10
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
chr5_+_92919043 0.15 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr1_-_32264356 0.14 ENST00000452755.2
SPOCD1
SPOC domain containing 1
chr2_+_234296792 0.14 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chr1_-_44497024 0.14 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr15_+_91446157 0.14 ENST00000559717.1
MAN2A2
mannosidase, alpha, class 2A, member 2
chr12_-_48744554 0.14 ENST00000544117.2
ENST00000548932.1
ENST00000549125.1
ENST00000301042.3
ENST00000547026.1
ZNF641
zinc finger protein 641
chr19_+_1491144 0.14 ENST00000233596.3
REEP6
receptor accessory protein 6
chrX_-_153744434 0.14 ENST00000369643.1
ENST00000393572.1
FAM3A
family with sequence similarity 3, member A
chr6_+_123100853 0.14 ENST00000356535.4
FABP7
fatty acid binding protein 7, brain
chr15_+_75105057 0.13 ENST00000309664.5
ENST00000562810.1
LMAN1L
lectin, mannose-binding, 1 like
chr2_-_217560248 0.13 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr16_-_19896220 0.13 ENST00000562469.1
ENST00000300571.2
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr12_-_54813229 0.13 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr17_+_78193443 0.13 ENST00000577155.1
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr2_+_74229812 0.13 ENST00000305799.7
TET3
tet methylcytosine dioxygenase 3
chrX_-_153744507 0.13 ENST00000442929.1
ENST00000426266.1
ENST00000359889.5
ENST00000369641.3
ENST00000447601.2
ENST00000434658.2
FAM3A
family with sequence similarity 3, member A
chr11_-_71752100 0.13 ENST00000542977.1
NUMA1
nuclear mitotic apparatus protein 1
chr16_+_30662050 0.13 ENST00000568754.1
PRR14
proline rich 14
chr14_-_24047965 0.13 ENST00000397118.3
ENST00000356300.4
JPH4
junctophilin 4
chr2_-_25475120 0.13 ENST00000380746.4
ENST00000402667.1
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr20_-_39317868 0.13 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr12_+_94656297 0.13 ENST00000545312.1
PLXNC1
plexin C1
chr19_+_17579556 0.12 ENST00000442725.1
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr19_+_17326521 0.12 ENST00000593597.1
USE1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr2_-_166930131 0.12 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr6_-_34524049 0.12 ENST00000374037.3
SPDEF
SAM pointed domain containing ETS transcription factor
chrX_+_48681768 0.12 ENST00000430858.1
HDAC6
histone deacetylase 6
chr8_+_22022800 0.12 ENST00000397814.3
BMP1
bone morphogenetic protein 1
chr1_+_152748848 0.12 ENST00000334371.2
LCE1F
late cornified envelope 1F
chr3_+_184080790 0.12 ENST00000430783.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr17_-_74533963 0.12 ENST00000293230.5
CYGB
cytoglobin
chr9_+_34646624 0.12 ENST00000450095.2
ENST00000556278.1
GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr6_-_31550192 0.12 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr7_-_45128472 0.12 ENST00000490531.2
NACAD
NAC alpha domain containing
chr1_-_16539094 0.12 ENST00000270747.3
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr17_-_73874654 0.12 ENST00000254816.2
TRIM47
tripartite motif containing 47
chr11_-_57089671 0.11 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr6_+_31949801 0.11 ENST00000428956.2
ENST00000498271.1
C4A
complement component 4A (Rodgers blood group)
chr15_-_40633101 0.11 ENST00000559313.1
C15orf52
chromosome 15 open reading frame 52
chr7_-_1595107 0.11 ENST00000414730.1
TMEM184A
transmembrane protein 184A
chr11_-_111784005 0.11 ENST00000527899.1
CRYAB
crystallin, alpha B
chr5_-_9903938 0.11 ENST00000511616.1
CTD-2143L24.1
CTD-2143L24.1
chr1_+_110453608 0.11 ENST00000369801.1
CSF1
colony stimulating factor 1 (macrophage)
chr11_-_67771513 0.11 ENST00000227471.2
UNC93B1
unc-93 homolog B1 (C. elegans)
chr7_+_73242069 0.11 ENST00000435050.1
CLDN4
claudin 4
chr7_+_18330035 0.11 ENST00000413509.2
HDAC9
histone deacetylase 9
chrX_-_152760934 0.11 ENST00000370210.1
ENST00000421080.2
HAUS7
HAUS augmin-like complex, subunit 7
chr19_-_44259136 0.11 ENST00000270066.6
SMG9
SMG9 nonsense mediated mRNA decay factor
chr8_-_141728760 0.11 ENST00000430260.2
PTK2
protein tyrosine kinase 2
chr20_+_9049742 0.11 ENST00000437503.1
PLCB4
phospholipase C, beta 4
chrX_+_154114635 0.11 ENST00000369446.2
F8A1
coagulation factor VIII-associated 1
chr11_-_64764435 0.11 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr22_+_46449674 0.11 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr1_-_32169920 0.11 ENST00000373672.3
ENST00000373668.3
COL16A1
collagen, type XVI, alpha 1
chr5_+_150020240 0.10 ENST00000519664.1
SYNPO
synaptopodin
chr15_-_49255632 0.10 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr1_+_113217043 0.10 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_113217345 0.10 ENST00000357443.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr17_+_7461580 0.10 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr12_+_6644443 0.10 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX1_NFIC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:1990637 response to prolactin(GO:1990637)
0.2 0.9 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.4 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.6 GO:1904124 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.3 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.3 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.6 GO:0060481 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481)
0.1 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:1903625 negative regulation of sperm motility(GO:1901318) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.4 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.6 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.3 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.5 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.2 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.1 GO:0048747 muscle fiber development(GO:0048747)
0.1 0.2 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.2 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.4 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.1 0.2 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.1 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.5 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.1 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.0 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.5 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.4 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.3 GO:1900164 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.6 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.2 GO:0051873 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.3 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.2 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.3 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.6 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.0 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.0 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.0 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.0 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.6 GO:0043260 laminin-11 complex(GO:0043260)
0.1 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0036024 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.2 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 0.5 GO:0005055 laminin receptor activity(GO:0005055)
0.1 1.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.4 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.3 GO:0035529 phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.4 GO:0005534 galactose binding(GO:0005534)
0.1 0.3 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.1 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:1990175 EH domain binding(GO:1990175)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.0 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.0 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.5 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543) peptidyl-proline 4-dioxygenase activity(GO:0031545)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors