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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TWIST1_SNAI1

Z-value: 0.85

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Transcription factors associated with TWIST1_SNAI1

Gene Symbol Gene ID Gene Info
ENSG00000122691.8 twist family bHLH transcription factor 1
ENSG00000124216.3 snail family transcriptional repressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SNAI1hg19_v2_chr20_+_48599506_485995360.276.1e-01Click!
TWIST1hg19_v2_chr7_-_19157248_19157295-0.207.0e-01Click!

Activity profile of TWIST1_SNAI1 motif

Sorted Z-values of TWIST1_SNAI1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_150406527 0.79 ENST00000520059.1
glutathione peroxidase 3 (plasma)
chr19_-_18391708 0.69 ENST00000600972.1
jun D proto-oncogene
chr1_+_27668505 0.63 ENST00000318074.5
synaptotagmin-like 1
chr7_+_149411860 0.59 ENST00000486744.1
KRAB-A domain containing 1
chr2_+_121493717 0.59 ENST00000418323.1
GLI family zinc finger 2
chr2_+_220306238 0.55 ENST00000435853.1
SPEG complex locus
chr7_-_120497178 0.47 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
tetraspanin 12
chr15_+_40544749 0.45 ENST00000559617.1
ENST00000560684.1
p21 protein (Cdc42/Rac)-activated kinase 6
chr2_+_219745020 0.44 ENST00000258411.3
wingless-type MMTV integration site family, member 10A
chr1_-_95285652 0.42 ENST00000442418.1
long intergenic non-protein coding RNA 1057
chr17_-_39677971 0.39 ENST00000393976.2
keratin 15
chr1_-_1850697 0.39 ENST00000378598.4
ENST00000416272.1
ENST00000310991.3
transmembrane protein 52
chr19_-_56109119 0.39 ENST00000587678.1
FLT3-interacting zinc finger 1
chr19_+_18794470 0.38 ENST00000321949.8
ENST00000338797.6
CREB regulated transcription coactivator 1
chr19_+_55795493 0.36 ENST00000309383.1
BR serine/threonine kinase 1
chr19_-_48673465 0.35 ENST00000598938.1
ligase I, DNA, ATP-dependent
chr9_-_140142222 0.34 ENST00000344774.4
ENST00000388932.2
family with sequence similarity 166, member A
chr12_+_65174519 0.33 ENST00000229088.6
TBC1 domain family, member 30
chr9_-_138987115 0.33 ENST00000277554.2
NACC family member 2, BEN and BTB (POZ) domain containing
chr17_+_79968655 0.33 ENST00000583744.1
alveolar soft part sarcoma chromosome region, candidate 1
chr11_+_1855645 0.32 ENST00000381968.3
ENST00000381978.3
synaptotagmin VIII
chr1_-_16556038 0.32 ENST00000375605.2
chromosome 1 open reading frame 134
chr17_+_43213004 0.32 ENST00000586346.1
ENST00000398322.3
ENST00000592162.1
ENST00000376955.4
ENST00000321854.8
acyl-CoA binding domain containing 4
chr9_+_92219919 0.31 ENST00000252506.6
ENST00000375769.1
growth arrest and DNA-damage-inducible, gamma
chr19_-_5567842 0.29 ENST00000587632.1
tissue differentiation-inducing non-protein coding RNA
chr19_-_6415695 0.29 ENST00000594496.1
ENST00000594745.1
ENST00000600480.1
KH-type splicing regulatory protein
chr1_+_60280458 0.28 ENST00000455990.1
ENST00000371208.3
hook microtubule-tethering protein 1
chr14_-_23652849 0.28 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr4_-_11430221 0.28 ENST00000514690.1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr21_+_37507210 0.27 ENST00000290354.5
carbonyl reductase 3
chr19_-_10420459 0.27 ENST00000403352.1
ENST00000403903.3
zinc finger, GATA-like protein 1
chr5_-_42811986 0.27 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr19_+_35630926 0.26 ENST00000588081.1
ENST00000589121.1
FXYD domain containing ion transport regulator 1
chr17_+_4843594 0.26 ENST00000570328.1
ring finger protein 167
chr6_-_33160231 0.26 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
collagen, type XI, alpha 2
chr14_-_59932044 0.26 ENST00000395116.1
G protein-coupled receptor 135
chr20_+_43538692 0.26 ENST00000217074.4
ENST00000255136.3
poly(A) binding protein, cytoplasmic 1-like
chr4_+_142557717 0.26 ENST00000320650.4
ENST00000296545.7
interleukin 15
chrX_+_105969893 0.25 ENST00000255499.2
ring finger protein 128, E3 ubiquitin protein ligase
chr20_-_60942361 0.25 ENST00000252999.3
laminin, alpha 5
chr11_+_62379194 0.25 ENST00000525801.1
ENST00000534093.1
retinal outer segment membrane protein 1
chr1_+_8378140 0.25 ENST00000377479.2
solute carrier family 45, member 1
chr17_+_63096903 0.25 ENST00000582940.1
RP11-160O5.1
chr19_-_49843539 0.24 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
chr19_-_17932314 0.24 ENST00000598577.1
ENST00000317306.7
ENST00000379695.5
insulin-like 3 (Leydig cell)
chr19_-_5567996 0.24 ENST00000448587.1
tissue differentiation-inducing non-protein coding RNA
chr9_+_139746792 0.24 ENST00000317446.2
ENST00000445819.1
MAM domain containing 4
chr11_+_65779283 0.23 ENST00000312134.2
cystatin E/M
chr16_-_30393752 0.23 ENST00000566517.1
ENST00000605106.1
septin 1
Uncharacterized protein
chr1_+_3385085 0.23 ENST00000445297.1
Rho guanine nucleotide exchange factor (GEF) 16
chr17_+_78193443 0.23 ENST00000577155.1
solute carrier family 26 (anion exchanger), member 11
chr22_-_46373004 0.23 ENST00000339464.4
wingless-type MMTV integration site family, member 7B
chr17_+_39421591 0.22 ENST00000391355.1
keratin associated protein 9-6
chr1_-_154178803 0.22 ENST00000368525.3
chromosome 1 open reading frame 189
chr14_-_81902516 0.22 ENST00000554710.1
stonin 2
chr19_+_39897943 0.22 ENST00000600033.1
ZFP36 ring finger protein
chr14_+_77425972 0.22 ENST00000553613.1
RP11-7F17.7
chr8_-_53477968 0.21 ENST00000523939.1
ENST00000358543.4
family with sequence similarity 150, member A
chr16_-_850723 0.21 ENST00000248150.4
guanine nucleotide binding protein (G protein), gamma 13
chr21_-_38338773 0.21 ENST00000399120.1
ENST00000419461.1
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr2_-_192016276 0.21 ENST00000413064.1
signal transducer and activator of transcription 4
chr19_-_10628098 0.21 ENST00000590601.1
sphingosine-1-phosphate receptor 5
chr16_-_70712229 0.21 ENST00000562883.2
metastasis suppressor 1-like
chr2_+_172864490 0.21 ENST00000315796.4
methionyl aminopeptidase type 1D (mitochondrial)
chr2_+_205410516 0.20 ENST00000406610.2
ENST00000462231.1
par-3 family cell polarity regulator beta
chr11_+_45168182 0.20 ENST00000526442.1
PR domain containing 11
chr8_+_145726472 0.20 ENST00000528430.1
protein phosphatase 1, regulatory subunit 16A
chr6_-_75994025 0.20 ENST00000518161.1
transmembrane protein 30A
chr11_-_2924720 0.20 ENST00000455942.2
solute carrier family 22 (organic cation transporter), member 18 antisense
chr16_+_3014269 0.19 ENST00000575885.1
ENST00000571007.1
ENST00000319500.6
kringle containing transmembrane protein 2
chr20_+_43538756 0.19 ENST00000537323.1
ENST00000217073.2
poly(A) binding protein, cytoplasmic 1-like
chr16_+_67197288 0.19 ENST00000264009.8
ENST00000421453.1
heat shock transcription factor 4
chr20_+_49348109 0.19 ENST00000396039.1
par-6 family cell polarity regulator beta
chr1_-_85666688 0.19 ENST00000341460.5
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr7_+_74379083 0.19 ENST00000361825.7
GATS protein-like 1
chr19_+_41856816 0.18 ENST00000539627.1
transmembrane protein 91
chr17_-_71258491 0.18 ENST00000397671.1
cleavage and polyadenylation specific factor 4-like
chr13_+_103046954 0.18 ENST00000606448.1
FGF14 antisense RNA 2
chr4_-_168155169 0.18 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr12_+_7055631 0.18 ENST00000543115.1
ENST00000399448.1
protein tyrosine phosphatase, non-receptor type 6
chr8_+_22429205 0.18 ENST00000520207.1
sorbin and SH3 domain containing 3
chr19_-_33793430 0.18 ENST00000498907.2
CCAAT/enhancer binding protein (C/EBP), alpha
chr6_+_1312675 0.18 ENST00000296839.2
forkhead box Q1
chr1_+_33352036 0.18 ENST00000373467.3
hippocalcin
chr5_+_76506706 0.18 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
phosphodiesterase 8B
chr14_+_77647966 0.18 ENST00000554766.1
transmembrane protein 63C
chr4_+_106816644 0.17 ENST00000506666.1
ENST00000503451.1
nephronectin
chr16_-_3086927 0.17 ENST00000572449.1
coiled-coil domain containing 64B
chr6_-_30899924 0.17 ENST00000359086.3
surfactant associated 2
chr7_+_24612848 0.17 ENST00000432190.1
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr10_+_99258625 0.17 ENST00000370664.3
ubiquitin domain containing 1
chr15_+_31658349 0.17 ENST00000558844.1
Kruppel-like factor 13
chr2_+_30670077 0.17 ENST00000466477.1
ENST00000465200.1
ENST00000379509.3
ENST00000319406.4
ENST00000488144.1
ENST00000465538.1
ENST00000309052.4
ENST00000359433.1
lysocardiolipin acyltransferase 1
chr16_+_718086 0.17 ENST00000315082.4
ENST00000563134.1
ras homolog family member T2
chr19_-_12624647 0.17 ENST00000455490.1
zinc finger protein 709
chr1_+_6508100 0.17 ENST00000461727.1
espin
chr7_-_91875358 0.17 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1, ankyrin repeat containing
chr16_+_616995 0.17 ENST00000293874.2
ENST00000409527.2
ENST00000424439.2
ENST00000540585.1
phosphatidylinositol glycan anchor biosynthesis, class Q
NHL repeat containing 4
chr3_+_49059038 0.17 ENST00000451378.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr4_+_166300084 0.16 ENST00000402744.4
carboxypeptidase E
chr8_+_96037255 0.16 ENST00000286687.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr12_+_26274917 0.16 ENST00000538142.1
sarcospan
chr11_-_3013497 0.16 ENST00000448187.1
ENST00000532325.2
ENST00000399614.2
nucleosome assembly protein 1-like 4
chr3_-_11761068 0.16 ENST00000418000.1
ENST00000417206.2
vestigial like 4 (Drosophila)
chr19_-_54676846 0.16 ENST00000301187.4
transmembrane channel-like 4
chr14_-_81902791 0.16 ENST00000557055.1
stonin 2
chr3_-_101395936 0.16 ENST00000461821.1
zinc finger and BTB domain containing 11
chr19_-_44008863 0.16 ENST00000601646.1
pleckstrin homology-like domain, family B, member 3
chr4_+_106816592 0.16 ENST00000379987.2
ENST00000453617.2
ENST00000427316.2
ENST00000514622.1
ENST00000305572.8
nephronectin
chr5_+_139027877 0.16 ENST00000302517.3
CXXC finger protein 5
chr11_-_75141206 0.16 ENST00000376292.4
kelch-like family member 35
chr11_+_560956 0.16 ENST00000397582.3
ENST00000344375.4
ENST00000397583.3
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr14_+_23025534 0.15 ENST00000557595.1
Uncharacterized protein
chr9_+_19408919 0.15 ENST00000380376.1
alkaline ceramidase 2
chr19_-_54676884 0.15 ENST00000376591.4
transmembrane channel-like 4
chr8_+_21881636 0.15 ENST00000520125.1
ENST00000521157.1
ENST00000397940.1
ENST00000522813.1
nucleophosmin/nucleoplasmin 2
chr19_+_5904866 0.15 ENST00000339485.3
vimentin-type intermediate filament associated coiled-coil protein
chr19_-_59010565 0.15 ENST00000594786.1
solute carrier family 27 (fatty acid transporter), member 5
chr4_+_142557771 0.15 ENST00000514653.1
interleukin 15
chr5_+_44809027 0.15 ENST00000507110.1
mitochondrial ribosomal protein S30
chr8_-_81083731 0.15 ENST00000379096.5
tumor protein D52
chr6_+_32811861 0.15 ENST00000453426.1
TAP1 and PSMB8 antisense RNA 1
chr11_+_86511549 0.15 ENST00000533902.2
protease, serine, 23
chr8_+_145490549 0.15 ENST00000340695.2
scleraxis homolog A (mouse)
chr6_+_31540056 0.15 ENST00000418386.2
lymphotoxin alpha
chr7_-_150780487 0.15 ENST00000482202.1
transmembrane and ubiquitin-like domain containing 1
chr7_-_27169801 0.15 ENST00000511914.1
homeobox A4
chr17_-_73761222 0.15 ENST00000437911.1
ENST00000225614.2
galactokinase 1
chr18_+_29078131 0.15 ENST00000585206.1
desmoglein 2
chr8_-_81083890 0.15 ENST00000518937.1
tumor protein D52
chr1_-_40254482 0.14 ENST00000397360.2
ENST00000372827.3
bone morphogenetic protein 8b
chr22_+_27068766 0.14 ENST00000435162.1
ENST00000437071.1
ENST00000440816.1
ENST00000421253.1
CTA-211A9.5
chr17_-_70417365 0.14 ENST00000580948.1
long intergenic non-protein coding RNA 511
chr15_-_44969086 0.14 ENST00000434130.1
ENST00000560780.1
protein associated with topoisomerase II homolog 2 (yeast)
chr15_+_69365272 0.14 ENST00000559914.1
ENST00000558369.1
long intergenic non-protein coding RNA 277
chr7_-_150780609 0.14 ENST00000297533.4
transmembrane and ubiquitin-like domain containing 1
chr15_+_67547163 0.14 ENST00000335894.4
IQ motif containing H
chr11_+_66824276 0.14 ENST00000308831.2
ras homolog family member D
chr14_-_67982146 0.14 ENST00000557779.1
ENST00000557006.1
transmembrane protein 229B
chr2_+_14772810 0.14 ENST00000295092.2
ENST00000331243.4
family with sequence similarity 84, member A
chr11_+_57509020 0.14 ENST00000388857.4
ENST00000528798.1
chromosome 11 open reading frame 31
chr16_-_4664382 0.14 ENST00000591113.1
UBA-like domain containing 1
chr16_+_2106134 0.14 ENST00000467949.1
tuberous sclerosis 2
chr19_-_1490398 0.14 ENST00000588671.1
ENST00000300954.5
proprotein convertase subtilisin/kexin type 4
chr11_+_706219 0.13 ENST00000533500.1
EPS8-like 2
chr12_-_62586543 0.13 ENST00000416284.3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chrX_-_45710920 0.13 ENST00000456532.1
RP5-1158E12.3
chr13_+_95364963 0.13 ENST00000438290.2
SOX21 antisense RNA 1 (head to head)
chr19_-_49565254 0.13 ENST00000593537.1
neurotrophin 4
chr8_-_143823816 0.13 ENST00000246515.1
secreted LY6/PLAUR domain containing 1
chr2_+_74881432 0.13 ENST00000453930.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr8_+_96037205 0.13 ENST00000396124.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr16_+_71660052 0.13 ENST00000567566.1
MARVEL domain containing 3
chr14_-_69262947 0.13 ENST00000557086.1
ZFP36 ring finger protein-like 1
chr15_-_71055878 0.13 ENST00000322954.6
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr11_+_27062272 0.13 ENST00000529202.1
ENST00000533566.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr5_+_170288856 0.13 ENST00000523189.1
RAN binding protein 17
chr19_-_18717627 0.13 ENST00000392386.3
cytokine receptor-like factor 1
chr8_-_144815966 0.13 ENST00000388913.3
family with sequence similarity 83, member H
chr5_-_137071756 0.13 ENST00000394937.3
ENST00000309755.4
kelch-like family member 3
chr11_+_86511569 0.13 ENST00000441050.1
protease, serine, 23
chr6_+_109416684 0.13 ENST00000521522.1
ENST00000524064.1
ENST00000522608.1
ENST00000521503.1
ENST00000519407.1
ENST00000519095.1
ENST00000368968.2
ENST00000522490.1
ENST00000523209.1
ENST00000368970.2
ENST00000520883.1
ENST00000523787.1
centrosomal protein 57kDa-like 1
chr6_+_80341000 0.13 ENST00000369838.4
SH3 domain binding glutamic acid-rich protein like 2
chr7_-_91875109 0.13 ENST00000412043.2
ENST00000430102.1
ENST00000425073.1
ENST00000394503.2
ENST00000454017.1
ENST00000440209.1
ENST00000413688.1
ENST00000452773.1
ENST00000433016.1
ENST00000394505.2
ENST00000422347.1
ENST00000458493.1
ENST00000425919.1
KRIT1, ankyrin repeat containing
chr10_-_46970474 0.13 ENST00000503753.1
ENST00000374321.4
synaptotagmin XV
chr17_-_73844722 0.13 ENST00000586257.1
WW domain binding protein 2
chr14_-_69262789 0.13 ENST00000557022.1
ZFP36 ring finger protein-like 1
chr1_-_223537475 0.12 ENST00000344029.6
ENST00000494793.2
ENST00000366878.4
ENST00000366877.3
sushi domain containing 4
chr5_+_94890840 0.12 ENST00000504763.1
arylsulfatase family, member K
chr7_+_2687173 0.12 ENST00000403167.1
tweety family member 3
chr6_+_31950150 0.12 ENST00000537134.1
complement component 4A (Rodgers blood group)
chr12_-_121972556 0.12 ENST00000545022.1
lysine (K)-specific demethylase 2B
chr8_-_145753940 0.12 ENST00000532827.1
chromosome 8 open reading frame 82
chr2_+_220306745 0.12 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG complex locus
chr8_-_99306564 0.12 ENST00000430223.2
NIPA-like domain containing 2
chr3_+_42544084 0.12 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
vasoactive intestinal peptide receptor 1
chr15_+_81071684 0.12 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199
chr12_-_53601055 0.12 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
integrin, beta 7
chr12_-_132628847 0.12 ENST00000397333.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr15_-_71055769 0.12 ENST00000539319.1
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr8_+_67687773 0.12 ENST00000518388.1
serum/glucocorticoid regulated kinase family, member 3
chr4_-_2420335 0.12 ENST00000503000.1
zinc finger, FYVE domain containing 28
chr1_-_22215192 0.12 ENST00000374673.3
heparan sulfate proteoglycan 2
chr1_+_178694300 0.12 ENST00000367635.3
Ral GEF with PH domain and SH3 binding motif 2
chr4_-_177116772 0.12 ENST00000280191.2
spermatogenesis associated 4
chr11_+_27062860 0.12 ENST00000528583.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr19_+_3708338 0.12 ENST00000590545.1
tight junction protein 3
chr19_+_7710774 0.12 ENST00000602355.1
syntaxin binding protein 2
chr5_+_7373230 0.12 ENST00000500616.2
CTD-2296D1.5
chr2_+_120517174 0.12 ENST00000263708.2
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr2_-_228028829 0.12 ENST00000396625.3
ENST00000329662.7
collagen, type IV, alpha 4
chr8_-_12612962 0.11 ENST00000398246.3
LON peptidase N-terminal domain and ring finger 1
chr2_+_17721920 0.11 ENST00000295156.4
visinin-like 1
chr2_-_169746878 0.11 ENST00000282074.2
SPC25, NDC80 kinetochore complex component
chr8_+_107670064 0.11 ENST00000312046.6
oxidation resistance 1
chr12_-_46663734 0.11 ENST00000550173.1
solute carrier family 38, member 1
chr16_+_30675654 0.11 ENST00000287468.5
ENST00000395073.2
fibrosin
chr2_+_66666432 0.11 ENST00000495021.2
Meis homeobox 1
chr19_+_2249308 0.11 ENST00000592877.1
ENST00000221496.4
anti-Mullerian hormone
chr20_+_9049742 0.11 ENST00000437503.1
phospholipase C, beta 4

Network of associatons between targets according to the STRING database.

First level regulatory network of TWIST1_SNAI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 0.5 GO:0045062 extrathymic T cell selection(GO:0045062)
0.2 0.5 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.1 0.8 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.4 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.5 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.1 0.3 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.1 0.2 GO:0061193 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.3 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.2 GO:0003164 His-Purkinje system development(GO:0003164)
0.1 0.1 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 0.2 GO:0060032 notochord regression(GO:0060032)
0.1 0.3 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 0.4 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.3 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.5 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.1 GO:1902232 regulation of interleukin-4-mediated signaling pathway(GO:1902214) regulation of positive thymic T cell selection(GO:1902232)
0.0 0.2 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.5 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) transformation of host cell by virus(GO:0019087) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) renal water absorption(GO:0070295)
0.0 0.1 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.1 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0021557 optic cup structural organization(GO:0003409) oculomotor nerve development(GO:0021557) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.7 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.0 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.0 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.0 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
0.0 0.1 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.0 GO:0010360 negative regulation of anion channel activity(GO:0010360) negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738) negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.0 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.0 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0006311 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.6 GO:0060042 retina morphogenesis in camera-type eye(GO:0060042)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0035768 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.0 0.0 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0015911 plasma membrane long-chain fatty acid transport(GO:0015911)
0.0 0.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.0 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.2 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.0 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.0 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0035976 AP1 complex(GO:0035976)
0.1 0.1 GO:0031300 intrinsic component of organelle membrane(GO:0031300)
0.1 0.3 GO:0043260 laminin-11 complex(GO:0043260)
0.1 0.3 GO:0034678 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)
0.1 0.2 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.2 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0036284 tubulobulbar complex(GO:0036284)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 0.3 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.0 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.9 GO:0008430 selenium binding(GO:0008430)
0.1 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.2 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.1 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.0 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.0 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.0 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.0 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts