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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for XBP1

Z-value: 0.74

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Transcription factors associated with XBP1

Gene Symbol Gene ID Gene Info
ENSG00000100219.12 X-box binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
XBP1hg19_v2_chr22_-_29196546_291965850.721.1e-01Click!

Activity profile of XBP1 motif

Sorted Z-values of XBP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_171758344 0.44 ENST00000336824.4
ENST00000423424.1
fibronectin type III domain containing 3B
chr3_-_57583130 0.42 ENST00000303436.6
ADP-ribosylation factor 4
chr6_+_43968306 0.38 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
chromosome 6 open reading frame 223
chr11_-_64646086 0.35 ENST00000320631.3
EH-domain containing 1
chr6_+_83903061 0.30 ENST00000369724.4
ENST00000539997.1
RWD domain containing 2A
chr5_-_121413974 0.28 ENST00000231004.4
lysyl oxidase
chr3_-_57583052 0.26 ENST00000496292.1
ENST00000489843.1
ADP-ribosylation factor 4
chr21_-_18985158 0.26 ENST00000339775.6
BTG family, member 3
chr3_-_57583185 0.25 ENST00000463880.1
ADP-ribosylation factor 4
chr20_-_62199427 0.25 ENST00000427522.2
helicase with zinc finger 2, transcriptional coactivator
chr2_-_214017151 0.24 ENST00000452786.1
IKAROS family zinc finger 2 (Helios)
chr1_-_24126023 0.23 ENST00000429356.1
UDP-galactose-4-epimerase
chr10_+_112257596 0.23 ENST00000369583.3
dual specificity phosphatase 5
chr19_+_33182823 0.22 ENST00000397061.3
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr10_-_128077024 0.22 ENST00000368679.4
ENST00000368676.4
ENST00000448723.1
ADAM metallopeptidase domain 12
chr1_-_119682812 0.20 ENST00000537870.1
tryptophanyl tRNA synthetase 2, mitochondrial
chr21_-_18985230 0.20 ENST00000457956.1
ENST00000348354.6
BTG family, member 3
chr6_-_83902933 0.18 ENST00000512866.1
ENST00000510258.1
ENST00000503094.1
ENST00000283977.4
ENST00000513973.1
ENST00000508748.1
phosphoglucomutase 3
chr20_-_17662705 0.17 ENST00000455029.2
ribosome binding protein 1
chr9_+_139377947 0.17 ENST00000354376.1
chromosome 9 open reading frame 163
chr1_+_26758849 0.16 ENST00000533087.1
ENST00000531312.1
ENST00000525165.1
ENST00000525326.1
ENST00000525546.1
ENST00000436153.2
ENST00000530781.1
dehydrodolichyl diphosphate synthase
chr10_-_99205607 0.16 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
exosome component 1
chr1_-_11120057 0.16 ENST00000376957.2
spermidine synthase
chr10_-_18948208 0.15 ENST00000607346.1
ARL5B antisense RNA 1
chr11_-_118927880 0.15 ENST00000527038.2
hypoxia up-regulated 1
chr5_+_176730769 0.15 ENST00000303204.4
ENST00000503216.1
PRELI domain containing 1
chr1_+_27669719 0.15 ENST00000473280.1
synaptotagmin-like 1
chr7_+_16793160 0.15 ENST00000262067.4
tetraspanin 13
chr12_-_133405409 0.14 ENST00000545875.1
ENST00000456883.2
golgin A3
chr5_-_171881362 0.14 ENST00000519643.1
SH3 and PX domains 2B
chr4_+_128982490 0.14 ENST00000394288.3
ENST00000432347.2
ENST00000264584.5
ENST00000441387.1
ENST00000427266.1
ENST00000354456.3
La ribonucleoprotein domain family, member 1B
chr20_-_17662878 0.14 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
ribosome binding protein 1
chr3_-_10362725 0.13 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
SEC13 homolog (S. cerevisiae)
chr5_+_154238149 0.13 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CCR4-NOT transcription complex, subunit 8
chr12_-_28123206 0.13 ENST00000542963.1
ENST00000535992.1
parathyroid hormone-like hormone
chr7_-_128045984 0.13 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr2_+_64681219 0.13 ENST00000238875.5
lectin, galactoside-binding-like
chr11_-_66056478 0.13 ENST00000431556.2
ENST00000528575.1
Yip1 interacting factor homolog A (S. cerevisiae)
chr22_+_20850171 0.13 ENST00000445987.1
mediator complex subunit 15
chr7_-_6523688 0.13 ENST00000490996.1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr2_+_85132749 0.13 ENST00000233143.4
thymosin beta 10
chr15_-_60690932 0.12 ENST00000559818.1
annexin A2
chr12_+_107349497 0.12 ENST00000548125.1
ENST00000280756.4
chromosome 12 open reading frame 23
chr19_-_8373173 0.12 ENST00000537716.2
ENST00000301458.5
CD320 molecule
chr11_-_118927561 0.12 ENST00000530473.1
hypoxia up-regulated 1
chr11_-_68039364 0.12 ENST00000533310.1
ENST00000304271.6
ENST00000527280.1
chromosome 11 open reading frame 24
chr1_+_21835858 0.12 ENST00000539907.1
ENST00000540617.1
ENST00000374840.3
alkaline phosphatase, liver/bone/kidney
chr1_-_24126051 0.12 ENST00000445705.1
UDP-galactose-4-epimerase
chr17_-_42276574 0.12 ENST00000589805.1
ataxin 7-like 3
chr14_-_24664540 0.11 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
transmembrane 9 superfamily member 1
chrX_+_9431324 0.11 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr1_+_26758790 0.11 ENST00000427245.2
ENST00000525682.2
ENST00000236342.7
ENST00000526219.1
ENST00000374185.3
ENST00000360009.2
dehydrodolichyl diphosphate synthase
chr12_+_58120044 0.11 ENST00000542466.2
AGAP2 antisense RNA 1
chr11_-_118927816 0.11 ENST00000534233.1
ENST00000532752.1
ENST00000525859.1
ENST00000404233.3
ENST00000532421.1
ENST00000543287.1
ENST00000527310.2
ENST00000529972.1
hypoxia up-regulated 1
chr6_-_43596899 0.11 ENST00000307126.5
ENST00000452781.1
GTP binding protein 2
chr10_+_104678032 0.11 ENST00000369878.4
ENST00000369875.3
cyclin M2
chr17_-_27277615 0.11 ENST00000583747.1
ENST00000584236.1
PHD finger protein 12
chr19_+_29704142 0.11 ENST00000587859.1
ENST00000590607.1
CTB-32O4.2
chr5_-_171881491 0.10 ENST00000311601.5
SH3 and PX domains 2B
chr1_-_119683251 0.10 ENST00000369426.5
ENST00000235521.4
tryptophanyl tRNA synthetase 2, mitochondrial
chr8_+_56014949 0.10 ENST00000327381.6
XK, Kell blood group complex subunit-related family, member 4
chr8_-_124054484 0.10 ENST00000419562.2
derlin 1
chr8_+_104384616 0.10 ENST00000520337.1
collagen triple helix repeat containing 1
chr11_+_17298342 0.10 ENST00000530964.1
nucleobindin 2
chr9_-_35072585 0.10 ENST00000448530.1
valosin containing protein
chr19_-_54618650 0.10 ENST00000391757.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr10_+_75504105 0.10 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24 family member C
chr17_+_7184986 0.10 ENST00000317370.8
ENST00000571308.1
solute carrier family 2 (facilitated glucose transporter), member 4
chr14_+_102430855 0.10 ENST00000360184.4
dynein, cytoplasmic 1, heavy chain 1
chr1_-_161087802 0.10 ENST00000368010.3
prefoldin subunit 2
chr5_-_176730676 0.10 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24, member RAS oncogene family
chr17_+_46048497 0.10 ENST00000583352.1
CDK5 regulatory subunit associated protein 3
chr22_+_38864041 0.10 ENST00000216014.4
ENST00000409006.3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr12_-_106641728 0.09 ENST00000378026.4
cytoskeleton-associated protein 4
chr19_+_17186577 0.09 ENST00000595618.1
ENST00000594824.1
myosin IXB
chr10_+_32735177 0.09 ENST00000545067.1
coiled-coil domain containing 7
chr2_-_242255060 0.09 ENST00000413241.1
ENST00000423693.1
ENST00000428482.1
high density lipoprotein binding protein
chr19_+_55477711 0.09 ENST00000448584.2
ENST00000537859.1
ENST00000585500.1
ENST00000427260.2
ENST00000538819.1
ENST00000263437.6
NLR family, pyrin domain containing 2
chr14_-_24664776 0.09 ENST00000530468.1
ENST00000528010.1
ENST00000396854.4
ENST00000524835.1
ENST00000261789.4
ENST00000525592.1
transmembrane 9 superfamily member 1
chr9_+_101984577 0.09 ENST00000223641.4
Sec61 beta subunit
chr14_-_50087312 0.09 ENST00000298289.6
ribosomal protein L36a-like
chr19_-_19030157 0.09 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
coatomer protein complex, subunit epsilon
chr7_+_128379449 0.09 ENST00000479257.1
calumenin
chr7_-_6523755 0.08 ENST00000436575.1
ENST00000258739.4
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr19_+_47104553 0.08 ENST00000598871.1
ENST00000594523.1
calmodulin 3 (phosphorylase kinase, delta)
chr14_+_69951457 0.08 ENST00000322564.7
pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
chr4_-_83351005 0.08 ENST00000295470.5
heterogeneous nuclear ribonucleoprotein D-like
chr5_+_154238042 0.08 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
CCR4-NOT transcription complex, subunit 8
chr12_-_28122980 0.08 ENST00000395868.3
ENST00000534890.1
parathyroid hormone-like hormone
chr19_+_49468558 0.08 ENST00000331825.6
ferritin, light polypeptide
chr9_-_34523027 0.08 ENST00000399775.2
energy homeostasis associated
chrX_-_153059811 0.08 ENST00000427365.2
ENST00000444450.1
ENST00000370093.1
isocitrate dehydrogenase 3 (NAD+) gamma
chr15_-_60690163 0.08 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
annexin A2
chr17_+_8339164 0.08 ENST00000582665.1
ENST00000334527.7
ENST00000299734.7
nudE neurodevelopment protein 1-like 1
chr19_-_54619006 0.08 ENST00000391759.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr19_-_4670345 0.08 ENST00000599630.1
ENST00000262947.3
chromosome 19 open reading frame 10
chr16_+_2479390 0.08 ENST00000397066.4
cyclin F
chr3_+_127771212 0.07 ENST00000243253.3
ENST00000481210.1
Sec61 alpha 1 subunit (S. cerevisiae)
chr19_-_29704448 0.07 ENST00000304863.4
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr11_-_118927735 0.07 ENST00000526656.1
hypoxia up-regulated 1
chr12_-_133405288 0.07 ENST00000204726.3
golgin A3
chr5_+_154237778 0.07 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
CCR4-NOT transcription complex, subunit 8
chr7_-_19157248 0.07 ENST00000242261.5
twist family bHLH transcription factor 1
chr15_-_75165651 0.07 ENST00000562363.1
ENST00000564529.1
ENST00000268099.9
secretory carrier membrane protein 2
chr4_+_128982416 0.07 ENST00000326639.6
La ribonucleoprotein domain family, member 1B
chr9_-_35732362 0.07 ENST00000314888.9
ENST00000540444.1
talin 1
chr2_-_33824336 0.07 ENST00000431950.1
ENST00000403368.1
ENST00000441530.2
family with sequence similarity 98, member A
chr16_-_66959429 0.07 ENST00000420652.1
ENST00000299759.6
Ras-related associated with diabetes
chr9_+_114393634 0.07 ENST00000556107.1
ENST00000374294.3
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr2_-_88927092 0.07 ENST00000303236.3
eukaryotic translation initiation factor 2-alpha kinase 3
chr11_+_64851666 0.07 ENST00000525509.1
ENST00000294258.3
ENST00000526334.1
zinc finger protein-like 1
chr1_-_87379785 0.07 ENST00000401030.3
ENST00000370554.1
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr2_+_27255806 0.07 ENST00000238788.9
ENST00000404032.3
transmembrane protein 214
chr11_-_118972575 0.07 ENST00000432443.2
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr3_-_139108475 0.07 ENST00000515006.1
ENST00000513274.1
ENST00000514508.1
ENST00000507777.1
ENST00000512153.1
ENST00000333188.5
coatomer protein complex, subunit beta 2 (beta prime)
chr16_+_777118 0.07 ENST00000562141.1
hydroxyacylglutathione hydrolase-like
chr19_+_50353944 0.07 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
prostate tumor overexpressed 1
chr7_+_127292234 0.07 ENST00000354725.3
staphylococcal nuclease and tudor domain containing 1
chr18_-_34408693 0.07 ENST00000587382.1
ENST00000589049.1
ENST00000587129.1
tubulin polyglutamylase complex subunit 2
chr17_+_46048471 0.06 ENST00000578018.1
ENST00000579175.1
CDK5 regulatory subunit associated protein 3
chr9_+_35732312 0.06 ENST00000353704.2
cAMP responsive element binding protein 3
chr4_-_119757239 0.06 ENST00000280551.6
SEC24 family member D
chr3_-_128369643 0.06 ENST00000296255.3
ribophorin I
chrX_-_153059958 0.06 ENST00000370092.3
ENST00000217901.5
isocitrate dehydrogenase 3 (NAD+) gamma
chr19_+_19030497 0.06 ENST00000438170.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr21_+_45138941 0.06 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
pyridoxal (pyridoxine, vitamin B6) kinase
chr19_-_10444188 0.06 ENST00000293677.6
ribonucleoprotein, PTB-binding 1
chr1_+_228270361 0.06 ENST00000272102.5
ENST00000540651.1
ADP-ribosylation factor 1
chr3_-_156272872 0.06 ENST00000476217.1
signal sequence receptor, gamma (translocon-associated protein gamma)
chr18_+_44497455 0.06 ENST00000592005.1
katanin p60 subunit A-like 2
chr19_+_50354393 0.06 ENST00000391842.1
prostate tumor overexpressed 1
chr1_-_45988542 0.06 ENST00000424390.1
peroxiredoxin 1
chr5_+_126853301 0.06 ENST00000296666.8
ENST00000442138.2
ENST00000512635.2
proline-rich coiled-coil 1
chr19_+_50354430 0.06 ENST00000599732.1
prostate tumor overexpressed 1
chr12_+_48722763 0.05 ENST00000335017.1
H1 histone family, member N, testis-specific
chr22_+_45148432 0.05 ENST00000389774.2
ENST00000396119.2
ENST00000336963.4
ENST00000356099.6
ENST00000412433.1
Rho GTPase activating protein 8
chrX_+_153060090 0.05 ENST00000370086.3
ENST00000370085.3
signal sequence receptor, delta
chr3_+_50284321 0.05 ENST00000451956.1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr1_-_154946792 0.05 ENST00000412170.1
SHC (Src homology 2 domain containing) transforming protein 1
chr4_-_47916613 0.05 ENST00000381538.3
ENST00000329043.3
nuclear transcription factor, X-box binding-like 1
chr6_+_116692102 0.05 ENST00000359564.2
dermatan sulfate epimerase
chr1_-_155145721 0.05 ENST00000295682.4
keratinocyte associated protein 2
chr18_-_34408802 0.05 ENST00000590842.1
tubulin polyglutamylase complex subunit 2
chr6_+_7108210 0.05 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
ras responsive element binding protein 1
chr19_+_36606654 0.05 ENST00000588385.1
ENST00000585746.1
tubulin folding cofactor B
chr5_+_112196919 0.05 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
signal recognition particle 19kDa
chr7_+_128379346 0.05 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
calumenin
chr6_-_7313381 0.05 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
signal sequence receptor, alpha
chr22_+_21271714 0.05 ENST00000354336.3
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr4_-_119757322 0.05 ENST00000379735.5
SEC24 family member D
chr11_+_65819802 0.05 ENST00000528302.1
ENST00000322535.6
ENST00000524627.1
ENST00000533595.1
ENST00000530322.1
splicing factor 3b, subunit 2, 145kDa
chr12_-_109125285 0.05 ENST00000552871.1
ENST00000261401.3
coronin, actin binding protein, 1C
chr5_+_154238096 0.05 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CCR4-NOT transcription complex, subunit 8
chr2_-_15701422 0.05 ENST00000441750.1
ENST00000281513.5
neuroblastoma amplified sequence
chr19_-_39421377 0.05 ENST00000430193.3
ENST00000600042.1
ENST00000221431.6
seryl-tRNA synthetase 2, mitochondrial
chr16_-_28222797 0.05 ENST00000569951.1
ENST00000565698.1
exportin 6
chr4_-_47916543 0.04 ENST00000507489.1
nuclear transcription factor, X-box binding-like 1
chr2_-_170430366 0.04 ENST00000453153.2
ENST00000445210.1
FAST kinase domains 1
chr17_+_8339189 0.04 ENST00000585098.1
ENST00000380025.4
ENST00000402554.3
ENST00000584866.1
ENST00000582490.1
nudE neurodevelopment protein 1-like 1
chr5_+_9546306 0.04 ENST00000508179.1
small nucleolar RNA host gene 18 (non-protein coding)
chr17_+_15848231 0.04 ENST00000304222.2
adenosine A2b receptor
chr13_+_26042960 0.04 ENST00000255283.8
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr6_+_7107999 0.04 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
ras responsive element binding protein 1
chr2_-_99952769 0.04 ENST00000409434.1
ENST00000434323.1
ENST00000264255.3
thioredoxin domain containing 9
chr17_+_8339340 0.04 ENST00000580012.1
nudE neurodevelopment protein 1-like 1
chr19_+_50354462 0.04 ENST00000601675.1
prostate tumor overexpressed 1
chr18_-_44497308 0.04 ENST00000585916.1
ENST00000324794.7
ENST00000545673.1
protein inhibitor of activated STAT, 2
chr6_+_33168637 0.04 ENST00000374677.3
solute carrier family 39 (zinc transporter), member 7
chr1_+_1567474 0.04 ENST00000356026.5
matrix metallopeptidase 23B
chrX_+_47050236 0.04 ENST00000377351.4
ubiquitin-like modifier activating enzyme 1
chr2_-_242254595 0.04 ENST00000441124.1
ENST00000391976.2
high density lipoprotein binding protein
chr2_-_182521699 0.04 ENST00000374969.2
ENST00000339098.5
ENST00000374970.2
ceramide kinase-like
chr18_-_34409116 0.03 ENST00000334295.4
tubulin polyglutamylase complex subunit 2
chrX_+_47050798 0.03 ENST00000412206.1
ENST00000427561.1
ubiquitin-like modifier activating enzyme 1
chr13_+_46039037 0.03 ENST00000349995.5
component of oligomeric golgi complex 3
chr6_+_33168597 0.03 ENST00000374675.3
solute carrier family 39 (zinc transporter), member 7
chr2_+_171785824 0.03 ENST00000452526.2
golgi reassembly stacking protein 2, 55kDa
chr17_-_8059638 0.03 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
period circadian clock 1
chr10_+_89419370 0.03 ENST00000361175.4
ENST00000456849.1
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr1_+_145576007 0.03 ENST00000369298.1
protein inhibitor of activated STAT, 3
chr5_-_176730733 0.03 ENST00000504395.1
RAB24, member RAS oncogene family
chr19_+_19030478 0.03 ENST00000247003.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr13_-_52027134 0.03 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr4_+_40058411 0.03 ENST00000261435.6
ENST00000515550.1
NEDD4 binding protein 2
chr19_+_16187816 0.03 ENST00000588410.1
tropomyosin 4
chr4_-_83350580 0.03 ENST00000349655.4
ENST00000602300.1
heterogeneous nuclear ribonucleoprotein D-like
chr6_+_7107830 0.03 ENST00000379933.3
ras responsive element binding protein 1
chr10_-_22292675 0.03 ENST00000376946.1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr18_+_34409069 0.03 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
KIAA1328
chr1_+_6845384 0.03 ENST00000303635.7
calmodulin binding transcription activator 1
chr1_+_145575980 0.02 ENST00000393045.2
protein inhibitor of activated STAT, 3
chr10_+_64893039 0.02 ENST00000277746.6
ENST00000435510.2
nuclear receptor binding factor 2
chr10_+_32735030 0.02 ENST00000277657.6
ENST00000362006.5
coiled-coil domain containing 7
chr4_+_190992087 0.02 ENST00000553598.1
double homeobox 4 like 7
chr6_-_111927062 0.02 ENST00000359831.4
TRAF3 interacting protein 2
chr18_-_34408902 0.02 ENST00000593035.1
ENST00000383056.3
ENST00000588909.1
ENST00000590337.1
tubulin polyglutamylase complex subunit 2
chr9_-_112260531 0.02 ENST00000374541.2
ENST00000262539.3
protein tyrosine phosphatase, non-receptor type 3
chr15_-_43622736 0.02 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
leucine carboxyl methyltransferase 2
chr2_-_33824382 0.02 ENST00000238823.8
family with sequence similarity 98, member A
chr8_-_38126675 0.02 ENST00000531823.1
ENST00000534339.1
ENST00000524616.1
ENST00000422581.2
ENST00000424479.2
ENST00000419686.2
phosphatidic acid phosphatase type 2 domain containing 1B

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.1 0.3 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.9 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.2 GO:0044035 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.2 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.0 0.1 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0051495 positive regulation of cytoskeleton organization(GO:0051495)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.0 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.0 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.2 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport