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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZBTB49

Z-value: 0.30

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Transcription factors associated with ZBTB49

Gene Symbol Gene ID Gene Info
ENSG00000168826.11 zinc finger and BTB domain containing 49

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB49hg19_v2_chr4_+_4291924_42920110.059.3e-01Click!

Activity profile of ZBTB49 motif

Sorted Z-values of ZBTB49 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_118943930 0.17 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
chr4_+_53525573 0.15 ENST00000503051.1
USP46 antisense RNA 1
chr11_-_2950642 0.10 ENST00000314222.4
pleckstrin homology-like domain, family A, member 2
chr1_+_79115503 0.10 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr2_-_61244550 0.10 ENST00000421319.1
pseudouridylate synthase 10
chr6_-_109776901 0.09 ENST00000431946.1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr16_+_810728 0.09 ENST00000563941.1
ENST00000545450.2
ENST00000566549.1
mesothelin
chr2_+_47799601 0.08 ENST00000601243.1
CDNA: FLJ23120 fis, clone LNG07989; HCG1987724; Uncharacterized protein
chr16_+_811073 0.06 ENST00000382862.3
ENST00000563651.1
mesothelin
chr16_-_28621353 0.06 ENST00000567512.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr5_-_146833222 0.06 ENST00000534907.1
dihydropyrimidinase-like 3
chr15_-_55488817 0.06 ENST00000569386.1
ribosomal L24 domain containing 1
chr15_+_90728145 0.06 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr3_-_49055991 0.05 ENST00000441576.2
ENST00000420952.2
ENST00000341949.4
ENST00000395462.4
DALR anticodon binding domain containing 3
chr19_-_51466681 0.05 ENST00000456750.2
kallikrein-related peptidase 6
chr22_-_19166343 0.05 ENST00000215882.5
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr17_+_80009741 0.05 ENST00000578552.1
ENST00000320548.4
ENST00000581578.1
ENST00000583885.1
ENST00000583641.1
ENST00000581418.1
ENST00000355130.2
ENST00000306823.6
ENST00000392358.2
G protein pathway suppressor 1
chr17_-_80009650 0.04 ENST00000310496.4
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_+_140474181 0.04 ENST00000194155.4
protocadherin beta 2
chr4_+_128886424 0.04 ENST00000398965.1
chromosome 4 open reading frame 29
chr19_-_4182530 0.04 ENST00000601571.1
ENST00000601488.1
ENST00000305232.6
ENST00000381935.3
ENST00000337491.2
sirtuin 6
chr8_+_24151553 0.04 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chr19_-_54567035 0.04 ENST00000366170.2
ENST00000425006.2
V-set and transmembrane domain containing 1
chr2_+_95873257 0.04 ENST00000425953.1
AC092835.2
chr11_-_63993601 0.04 ENST00000545812.1
ENST00000394547.3
ENST00000317459.6
tRNA phosphotransferase 1
chr19_-_42894420 0.04 ENST00000597255.1
ENST00000222032.5
cornifelin
chr8_+_99129513 0.03 ENST00000522319.1
ENST00000401707.2
processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
chr14_+_35591928 0.03 ENST00000605870.1
ENST00000557404.3
KIAA0391
chr14_+_35591509 0.03 ENST00000604073.1
KIAA0391
chr19_+_50145328 0.03 ENST00000360565.3
SR-related CTD-associated factor 1
chr1_-_36863481 0.03 ENST00000315732.2
LSM10, U7 small nuclear RNA associated
chr11_+_63993738 0.03 ENST00000441250.2
ENST00000279206.3
nudix (nucleoside diphosphate linked moiety X)-type motif 22
chr22_-_20256054 0.03 ENST00000043402.7
reticulon 4 receptor
chr17_+_54671047 0.03 ENST00000332822.4
noggin
chr11_-_63993690 0.03 ENST00000394546.2
ENST00000541278.1
tRNA phosphotransferase 1
chr15_+_75639372 0.03 ENST00000566313.1
ENST00000568059.1
ENST00000568881.1
nei endonuclease VIII-like 1 (E. coli)
chr20_+_5731083 0.03 ENST00000445603.1
ENST00000442185.1
chromosome 20 open reading frame 196
chr2_+_234160217 0.03 ENST00000392017.4
ENST00000347464.5
ENST00000444735.1
ENST00000373525.5
ENST00000419681.1
autophagy related 16-like 1 (S. cerevisiae)
chr15_+_93749295 0.03 ENST00000599897.1
AC112693.2
chr10_+_64893039 0.03 ENST00000277746.6
ENST00000435510.2
nuclear receptor binding factor 2
chr11_+_108094786 0.02 ENST00000601453.1
ataxia telangiectasia mutated
chr3_+_52232102 0.02 ENST00000469224.1
ENST00000394965.2
ENST00000310271.2
ENST00000484952.1
aminolevulinate, delta-, synthase 1
chr14_+_35591735 0.02 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391
chr22_-_20255212 0.02 ENST00000416372.1
reticulon 4 receptor
chr15_+_75639773 0.02 ENST00000567657.1
nei endonuclease VIII-like 1 (E. coli)
chr18_+_32558208 0.02 ENST00000436190.2
microtubule-associated protein, RP/EB family, member 2
chr6_-_159240415 0.02 ENST00000367075.3
ezrin
chr3_-_184971817 0.02 ENST00000440662.1
ENST00000456310.1
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr7_-_44613494 0.02 ENST00000431640.1
ENST00000258772.5
DEAD (Asp-Glu-Ala-Asp) box helicase 56
chr20_+_33134619 0.02 ENST00000374837.3
microtubule-associated protein 1 light chain 3 alpha
chr19_+_17862274 0.02 ENST00000596536.1
ENST00000593870.1
ENST00000598086.1
ENST00000598932.1
ENST00000595023.1
ENST00000594068.1
ENST00000596507.1
ENST00000595033.1
ENST00000597718.1
FCH domain only 1
chr19_-_59070239 0.02 ENST00000595957.1
ENST00000253023.3
ubiquitin-conjugating enzyme E2M
chr18_+_32558380 0.02 ENST00000588349.2
microtubule-associated protein, RP/EB family, member 2
chr9_-_7800067 0.02 ENST00000358227.4
transmembrane protein 261
chr9_+_134378289 0.02 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
protein-O-mannosyltransferase 1
chrX_+_52780318 0.02 ENST00000375515.3
ENST00000276049.6
synovial sarcoma, X breakpoint 2B
chr14_+_35591858 0.02 ENST00000603544.1
KIAA0391
chr22_-_29196546 0.02 ENST00000403532.3
ENST00000216037.6
X-box binding protein 1
chr12_+_53835383 0.02 ENST00000429243.2
proline rich 13
chr22_+_21996549 0.02 ENST00000248958.4
stromal cell-derived factor 2-like 1
chr17_-_80231557 0.02 ENST00000392334.2
ENST00000314028.6
casein kinase 1, delta
chr1_-_151319283 0.02 ENST00000392746.3
regulatory factor X, 5 (influences HLA class II expression)
chr19_+_29097595 0.02 ENST00000587961.1
AC079466.1
chr12_+_124155652 0.02 ENST00000426174.2
ENST00000303372.5
tectonic family member 2
chr2_+_234160340 0.02 ENST00000417017.1
ENST00000392020.4
ENST00000392018.1
autophagy related 16-like 1 (S. cerevisiae)
chr14_-_23446900 0.01 ENST00000556731.1
ajuba LIM protein
chr6_-_43655511 0.01 ENST00000372133.3
ENST00000372116.1
ENST00000427312.1
mitochondrial ribosomal protein S18A
chr19_+_18669809 0.01 ENST00000602094.1
KxDL motif containing 1
chr2_+_27498289 0.01 ENST00000296097.3
ENST00000420191.1
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr14_+_77924204 0.01 ENST00000555133.1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chrX_+_64887512 0.01 ENST00000360270.5
moesin
chr9_-_88874519 0.01 ENST00000376001.3
ENST00000339137.3
chromosome 9 open reading frame 153
chr16_+_69166418 0.01 ENST00000314423.7
ENST00000562237.1
ENST00000567460.1
ENST00000566227.1
ENST00000352319.4
ENST00000563094.1
cirrhosis, autosomal recessive 1A (cirhin)
chr2_+_27237615 0.01 ENST00000458529.1
ENST00000402218.1
microtubule-associated protein, RP/EB family, member 3
chr1_-_220101944 0.01 ENST00000366926.3
ENST00000536992.1
solute carrier family 30, member 10
chr20_+_1115821 0.01 ENST00000435720.1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr22_-_42017021 0.01 ENST00000263256.6
desumoylating isopeptidase 1
chr6_-_109777128 0.01 ENST00000358807.3
ENST00000358577.3
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr8_-_16043780 0.01 ENST00000445506.2
macrophage scavenger receptor 1
chr3_-_172428959 0.01 ENST00000475381.1
ENST00000538775.1
ENST00000273512.3
ENST00000543711.1
neutral cholesterol ester hydrolase 1
chr20_-_32700075 0.01 ENST00000374980.2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr12_+_53835425 0.01 ENST00000549924.1
proline rich 13
chr22_-_29196511 0.01 ENST00000344347.5
X-box binding protein 1
chr14_+_79746249 0.01 ENST00000428277.2
neurexin 3
chr1_+_182808474 0.01 ENST00000367549.3
DEAH (Asp-Glu-Ala-His) box helicase 9
chr16_+_81069433 0.01 ENST00000299575.4
ATM interactor
chr15_+_75639296 0.01 ENST00000564500.1
ENST00000355059.4
ENST00000566752.1
nei endonuclease VIII-like 1 (E. coli)
chr16_-_28415162 0.01 ENST00000398944.3
ENST00000398943.3
ENST00000380876.4
eukaryotic translation initiation factor 3, subunit C-like
chr22_-_37915247 0.01 ENST00000251973.5
caspase recruitment domain family, member 10
chr8_+_24151620 0.01 ENST00000437154.2
ADAM metallopeptidase domain 28
chr12_+_53835539 0.01 ENST00000547368.1
ENST00000379786.4
ENST00000551945.1
proline rich 13
chr22_-_29196030 0.01 ENST00000405219.3
X-box binding protein 1
chr1_+_24117627 0.01 ENST00000400061.1
lysophospholipase II
chr16_+_28722809 0.01 ENST00000566866.1
eukaryotic translation initiation factor 3, subunit C
chr8_-_42396721 0.01 ENST00000518384.1
solute carrier family 20 (phosphate transporter), member 2
chr14_-_35591433 0.01 ENST00000261475.5
ENST00000555644.1
protein phosphatase 2, regulatory subunit B'', gamma
chr9_-_123676827 0.01 ENST00000546084.1
TNF receptor-associated factor 1
chr8_+_58907104 0.01 ENST00000361488.3
family with sequence similarity 110, member B
chr14_+_31959154 0.01 ENST00000550005.1
nucleotide binding protein-like
chr19_-_51611623 0.01 ENST00000421832.2
cytosolic thiouridylase subunit 1
chr2_+_27498331 0.00 ENST00000402462.1
ENST00000404433.1
ENST00000406962.1
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr14_+_79745746 0.00 ENST00000281127.7
neurexin 3
chr19_-_6481776 0.00 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENN/MADD domain containing 1C
chr14_-_35591156 0.00 ENST00000554361.1
protein phosphatase 2, regulatory subunit B'', gamma
chr1_+_8021713 0.00 ENST00000338639.5
ENST00000493678.1
ENST00000377493.5
parkinson protein 7
chr12_+_83080724 0.00 ENST00000548305.1
transmembrane and tetratricopeptide repeat containing 2
chr1_+_46806452 0.00 ENST00000536062.1
NOP2/Sun domain family, member 4
chr3_+_39424828 0.00 ENST00000273158.4
ENST00000431510.1
solute carrier family 25, member 38
chr13_-_100624012 0.00 ENST00000267294.4
Zic family member 5
chr12_+_40618764 0.00 ENST00000343742.2
leucine-rich repeat kinase 2
chr14_+_79745682 0.00 ENST00000557594.1
neurexin 3
chr16_-_18937480 0.00 ENST00000532700.2
SMG1 phosphatidylinositol 3-kinase-related kinase
chr16_+_28722684 0.00 ENST00000331666.6
ENST00000395587.1
ENST00000569690.1
ENST00000564243.1
eukaryotic translation initiation factor 3, subunit C
chrX_+_16185604 0.00 ENST00000400004.2
melanoma antigen family B, 17
chr16_+_30406721 0.00 ENST00000320159.2
zinc finger protein 48
chr7_-_103629963 0.00 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
reelin
chr9_-_97401782 0.00 ENST00000375326.4
fructose-1,6-bisphosphatase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB49

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.0 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.0 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619)
0.0 0.0 GO:1900100 epithelial cell differentiation involved in salivary gland development(GO:0060690) epithelial cell maturation involved in salivary gland development(GO:0060691) regulation of plasma cell differentiation(GO:1900098) positive regulation of plasma cell differentiation(GO:1900100) regulation of lactation(GO:1903487) positive regulation of lactation(GO:1903489)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.0 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)