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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZFHX3

Z-value: 0.25

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Transcription factors associated with ZFHX3

Gene Symbol Gene ID Gene Info
ENSG00000140836.10 zinc finger homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZFHX3hg19_v2_chr16_-_73093597_730935970.335.2e-01Click!

Activity profile of ZFHX3 motif

Sorted Z-values of ZFHX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_30899924 0.16 ENST00000359086.3
surfactant associated 2
chr5_+_140625147 0.13 ENST00000231173.3
protocadherin beta 15
chr14_+_39703112 0.11 ENST00000555143.1
ENST00000280082.3
melanoma inhibitory activity 2
chr15_+_76352178 0.10 ENST00000388942.3
chromosome 15 open reading frame 27
chr16_-_69385681 0.08 ENST00000288025.3
transmembrane emp24 protein transport domain containing 6
chr15_-_76352069 0.08 ENST00000305435.10
ENST00000563910.1
neuregulin 4
chr19_-_58864848 0.07 ENST00000263100.3
alpha-1-B glycoprotein
chr3_-_161089289 0.07 ENST00000497137.1
serine palmitoyltransferase, small subunit B
chrM_-_14670 0.07 ENST00000361681.2
mitochondrially encoded NADH dehydrogenase 6
chr14_+_38033252 0.06 ENST00000554829.1
RP11-356O9.1
chr12_-_91546926 0.05 ENST00000550758.1
decorin
chr16_-_75284758 0.05 ENST00000561970.1
breast cancer anti-estrogen resistance 1
chr7_-_100026280 0.05 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
zinc finger, CW type with PWWP domain 1
chr11_-_559377 0.05 ENST00000486629.1
chromosome 11 open reading frame 35
chr2_+_133174147 0.05 ENST00000329321.3
G protein-coupled receptor 39
chr2_-_14541060 0.05 ENST00000418420.1
ENST00000417751.1
long intergenic non-protein coding RNA 276
chr12_-_131200810 0.05 ENST00000536002.1
ENST00000544034.1
RIMS binding protein 2
RP11-662M24.2
chr22_-_22337204 0.05 ENST00000430142.1
ENST00000357179.5
topoisomerase (DNA) III beta
chr12_+_65996599 0.04 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
chr8_-_145754428 0.04 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
chromosome 8 open reading frame 82
chr12_+_59989918 0.04 ENST00000547379.1
ENST00000549465.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr1_+_162601774 0.04 ENST00000415555.1
discoidin domain receptor tyrosine kinase 2
chr12_-_10321754 0.04 ENST00000539518.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr2_+_190541153 0.04 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ankyrin and armadillo repeat containing
chr4_-_100356291 0.04 ENST00000476959.1
ENST00000482593.1
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr7_+_48211048 0.04 ENST00000435803.1
ATP-binding cassette, sub-family A (ABC1), member 13
chr9_+_44868935 0.03 ENST00000448436.2
RP11-160N1.10
chr8_+_104831440 0.03 ENST00000515551.1
regulating synaptic membrane exocytosis 2
chr5_+_60933634 0.03 ENST00000505642.1
chromosome 5 open reading frame 64
chr4_-_100356551 0.03 ENST00000209665.4
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_+_17685422 0.03 ENST00000395774.1
retinoic acid induced 1
chr19_+_50016610 0.03 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr6_-_32374900 0.03 ENST00000374995.3
ENST00000374993.1
ENST00000414363.1
ENST00000540315.1
ENST00000544175.1
ENST00000429232.2
ENST00000454136.3
ENST00000446536.2
butyrophilin-like 2 (MHC class II associated)
chr7_+_100026406 0.03 ENST00000414441.1
methylphosphate capping enzyme
chrM_+_10053 0.03 ENST00000361227.2
mitochondrially encoded NADH dehydrogenase 3
chr20_+_42187682 0.03 ENST00000373092.3
ENST00000373077.1
serum/glucocorticoid regulated kinase 2
chr7_+_143806607 0.03 ENST00000408979.2
olfactory receptor, family 2, subfamily A, member 2
chr20_+_42187608 0.03 ENST00000373100.1
serum/glucocorticoid regulated kinase 2
chrM_+_10464 0.03 ENST00000361335.1
mitochondrially encoded NADH dehydrogenase 4L
chr12_-_2944184 0.02 ENST00000337508.4
nuclear receptor interacting protein 2
chrM_+_8527 0.02 ENST00000361899.2
mitochondrially encoded ATP synthase 6
chrX_-_15288154 0.02 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ankyrin repeat and SOCS box containing 9
chr7_-_44580861 0.02 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1-like 1
chrM_+_14741 0.02 ENST00000361789.2
mitochondrially encoded cytochrome b
chrX_+_1710484 0.02 ENST00000313871.3
ENST00000381261.3
A kinase (PRKA) anchor protein 17A
chr11_-_107729287 0.02 ENST00000375682.4
solute carrier family 35, member F2
chrM_+_9207 0.02 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr17_-_26697304 0.02 ENST00000536498.1
vitronectin
chr19_+_926000 0.02 ENST00000263620.3
AT rich interactive domain 3A (BRIGHT-like)
chr6_-_161085291 0.02 ENST00000316300.5
lipoprotein, Lp(a)
chr9_-_123812542 0.02 ENST00000223642.1
complement component 5
chr17_+_41052808 0.02 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
glucose-6-phosphatase, catalytic subunit
chr1_-_160549235 0.02 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84 molecule
chr6_-_152793728 0.02 ENST00000495090.2
spectrin repeat containing, nuclear envelope 1
chr19_-_46234119 0.01 ENST00000317683.3
F-box protein 46
chr6_-_31681839 0.01 ENST00000409239.1
ENST00000461287.1
lymphocyte antigen 6 complex, locus G6E (pseudogene)
Uncharacterized protein
chr22_+_39101728 0.01 ENST00000216044.5
ENST00000484657.1
GTP binding protein 1
chr14_+_23709555 0.01 ENST00000430154.2
chromosome 14 open reading frame 164
chr16_-_15474904 0.01 ENST00000534094.1
nuclear pore complex interacting protein family, member A5
chr16_+_87636474 0.01 ENST00000284262.2
junctophilin 3
chr8_-_87242589 0.01 ENST00000419776.2
ENST00000297524.3
solute carrier family 7 (anionic amino acid transporter), member 13
chr12_+_59989791 0.01 ENST00000552432.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr1_+_170632250 0.01 ENST00000367760.3
paired related homeobox 1
chr5_+_95066823 0.01 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr6_+_28317685 0.01 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
zinc finger with KRAB and SCAN domains 3
chr2_-_40680578 0.01 ENST00000455476.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr4_-_155511887 0.01 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr12_-_11184006 0.01 ENST00000390675.2
taste receptor, type 2, member 31
chr8_+_98900132 0.01 ENST00000520016.1
matrilin 2
chr10_-_74283694 0.01 ENST00000398763.4
ENST00000418483.2
ENST00000489666.2
mitochondrial calcium uptake 1
chr4_-_22444733 0.01 ENST00000508133.1
G protein-coupled receptor 125
chrX_-_15619076 0.01 ENST00000252519.3
angiotensin I converting enzyme 2
chr4_-_69111401 0.01 ENST00000332644.5
transmembrane protease, serine 11B
chrX_-_110655306 0.01 ENST00000371993.2
doublecortin
chr13_-_30880979 0.01 ENST00000414289.1
katanin p60 subunit A-like 1
chr9_-_95298314 0.01 ENST00000344604.5
ENST00000375540.1
extracellular matrix protein 2, female organ and adipocyte specific
chr12_+_131438443 0.01 ENST00000261654.5
G protein-coupled receptor 133
chr21_+_40824003 0.01 ENST00000452550.1
SH3 domain binding glutamic acid-rich protein
chr13_-_30881134 0.01 ENST00000380617.3
ENST00000441394.1
katanin p60 subunit A-like 1
chr6_+_34204642 0.00 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr3_+_77088989 0.00 ENST00000461745.1
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr7_+_130126012 0.00 ENST00000341441.5
mesoderm specific transcript
chr6_+_126070726 0.00 ENST00000368364.3
hes-related family bHLH transcription factor with YRPW motif 2
chr3_-_114477787 0.00 ENST00000464560.1
zinc finger and BTB domain containing 20
chr3_+_46919235 0.00 ENST00000449590.1
parathyroid hormone 1 receptor
chr4_-_149365827 0.00 ENST00000344721.4
nuclear receptor subfamily 3, group C, member 2
chr19_+_54466179 0.00 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr7_+_150725510 0.00 ENST00000461373.1
ENST00000358849.4
ENST00000297504.6
ENST00000542328.1
ENST00000498578.1
ENST00000356058.4
ENST00000477719.1
ENST00000477092.1
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr4_-_68829226 0.00 ENST00000396188.2
transmembrane protease, serine 11A
chr3_+_69915363 0.00 ENST00000451708.1
microphthalmia-associated transcription factor
chr11_-_107729504 0.00 ENST00000265836.7
solute carrier family 35, member F2
chr8_-_18541603 0.00 ENST00000428502.2
pleckstrin and Sec7 domain containing 3
chr12_+_54410664 0.00 ENST00000303406.4
homeobox C4

Network of associatons between targets according to the STRING database.

First level regulatory network of ZFHX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)