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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZIC1

Z-value: 0.49

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Transcription factors associated with ZIC1

Gene Symbol Gene ID Gene Info
ZIC1
ENSG00000152977.5 Zic family member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC1hg19_v2_chr3_+_147127142_147127171-0.138.0e-01Click!

Activity profile of ZIC1 motif

Sorted Z-values of ZIC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_7105056 0.31 ENST00000504402.1
ENST00000499242.2
ENST00000501888.2
RP11-367J11.3
RP11-367J11.3
chr13_-_45048386 0.29 ENST00000472477.1
TSC22D1
TSC22 domain family, member 1
chr5_+_150406527 0.22 ENST00000520059.1
GPX3
glutathione peroxidase 3 (plasma)
chr2_-_99552620 0.21 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211L
KIAA1211-like
chr11_+_65779283 0.19 ENST00000312134.2
CST6
cystatin E/M
chr2_+_46769798 0.19 ENST00000238738.4
RHOQ
ras homolog family member Q
chr11_-_559377 0.19 ENST00000486629.1
C11orf35
chromosome 11 open reading frame 35
chr6_+_31540056 0.18 ENST00000418386.2
LTA
lymphotoxin alpha
chr4_+_24797085 0.18 ENST00000382120.3
SOD3
superoxide dismutase 3, extracellular
chr1_-_244615425 0.18 ENST00000366535.3
ADSS
adenylosuccinate synthase
chr1_+_61869748 0.18 ENST00000357977.5
NFIA
nuclear factor I/A
chr16_+_30996502 0.17 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
HSD3B7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr4_-_129208030 0.17 ENST00000503872.1
PGRMC2
progesterone receptor membrane component 2
chr6_-_35656685 0.17 ENST00000539068.1
ENST00000540787.1
FKBP5
FK506 binding protein 5
chr11_+_22646739 0.16 ENST00000428556.2
AC103801.2
AC103801.2
chr4_-_129207942 0.16 ENST00000503588.1
PGRMC2
progesterone receptor membrane component 2
chr17_+_60704762 0.16 ENST00000303375.5
MRC2
mannose receptor, C type 2
chr15_+_96904487 0.15 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr14_+_36295638 0.15 ENST00000543183.1
BRMS1L
breast cancer metastasis-suppressor 1-like
chr11_+_67777751 0.15 ENST00000316367.6
ENST00000007633.8
ENST00000342456.6
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr14_+_36295504 0.14 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr5_-_64920115 0.14 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr9_+_124329336 0.14 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr6_-_35656712 0.14 ENST00000357266.4
ENST00000542713.1
FKBP5
FK506 binding protein 5
chr5_-_126409159 0.14 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr19_+_55987998 0.13 ENST00000591164.1
ZNF628
zinc finger protein 628
chr6_+_90272488 0.13 ENST00000485637.1
ENST00000522705.1
ANKRD6
ankyrin repeat domain 6
chrX_+_77166172 0.13 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr10_-_62493223 0.13 ENST00000373827.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr18_+_76829441 0.13 ENST00000458297.2
ATP9B
ATPase, class II, type 9B
chr15_+_81589254 0.12 ENST00000394652.2
IL16
interleukin 16
chr1_+_2487800 0.12 ENST00000355716.4
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr19_+_41509851 0.12 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr4_-_89444883 0.11 ENST00000273968.4
PYURF
PIGY upstream reading frame
chr10_-_33623826 0.11 ENST00000374867.2
NRP1
neuropilin 1
chr3_+_49027771 0.11 ENST00000475629.1
ENST00000444213.1
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chrX_+_53078465 0.11 ENST00000375466.2
GPR173
G protein-coupled receptor 173
chr19_+_45409011 0.11 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr7_-_73256838 0.11 ENST00000297873.4
WBSCR27
Williams Beuren syndrome chromosome region 27
chr18_+_76829385 0.11 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATP9B
ATPase, class II, type 9B
chr16_-_4665023 0.11 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr19_+_13135790 0.10 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr2_+_169926047 0.10 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr19_+_50169081 0.10 ENST00000246784.3
BCL2L12
BCL2-like 12 (proline rich)
chr19_-_2740036 0.10 ENST00000586572.1
ENST00000269740.4
AC006538.4
SLC39A3
Uncharacterized protein
solute carrier family 39 (zinc transporter), member 3
chr10_-_33623564 0.09 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr4_+_95916947 0.09 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr16_-_4664860 0.09 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1
UBA-like domain containing 1
chr1_+_100316041 0.09 ENST00000370165.3
ENST00000370163.3
ENST00000294724.4
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr1_+_95699704 0.08 ENST00000370202.4
RWDD3
RWD domain containing 3
chrX_+_68835911 0.08 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chrX_+_46771848 0.08 ENST00000218343.4
PHF16
jade family PHD finger 3
chr12_+_13197218 0.08 ENST00000197268.8
KIAA1467
KIAA1467
chr11_+_66824346 0.08 ENST00000532559.1
RHOD
ras homolog family member D
chr6_-_168720382 0.08 ENST00000610183.1
ENST00000607983.1
ENST00000366795.3
DACT2
dishevelled-binding antagonist of beta-catenin 2
chr10_-_33624002 0.08 ENST00000432372.2
NRP1
neuropilin 1
chr19_+_54024251 0.08 ENST00000253144.9
ZNF331
zinc finger protein 331
chr6_-_34216766 0.07 ENST00000481533.1
ENST00000468145.1
ENST00000413013.2
ENST00000394990.4
ENST00000335352.3
C6orf1
chromosome 6 open reading frame 1
chr6_-_138428613 0.07 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr7_-_135412925 0.07 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr6_-_146285221 0.07 ENST00000367503.3
ENST00000438092.2
ENST00000275233.7
SHPRH
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr15_-_71407833 0.07 ENST00000449977.2
CT62
cancer/testis antigen 62
chr12_-_2966193 0.07 ENST00000382678.3
AC005841.1
Uncharacterized protein ENSP00000372125
chr17_-_4464081 0.07 ENST00000574154.1
GGT6
gamma-glutamyltransferase 6
chr1_+_95699740 0.07 ENST00000429514.2
ENST00000263893.6
RWDD3
RWD domain containing 3
chr1_+_100315613 0.06 ENST00000361915.3
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr16_-_31100284 0.06 ENST00000280606.6
PRSS53
protease, serine, 53
chr12_-_11036844 0.06 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr9_-_123639600 0.06 ENST00000373896.3
PHF19
PHD finger protein 19
chr8_-_82754427 0.06 ENST00000353788.4
ENST00000520618.1
ENST00000518183.1
ENST00000396330.2
ENST00000519119.1
ENST00000345957.4
SNX16
sorting nexin 16
chr10_-_36813162 0.06 ENST00000440465.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr18_+_61420169 0.06 ENST00000425392.1
ENST00000336429.2
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr16_+_28857916 0.06 ENST00000563591.1
SH2B1
SH2B adaptor protein 1
chr17_-_43045439 0.06 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chr7_-_102789629 0.05 ENST00000417955.1
ENST00000341533.4
ENST00000425379.1
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D
chr14_+_57735614 0.05 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr4_-_40632757 0.05 ENST00000511902.1
ENST00000505220.1
RBM47
RNA binding motif protein 47
chr15_+_41245160 0.05 ENST00000444189.2
ENST00000446533.3
CHAC1
ChaC, cation transport regulator homolog 1 (E. coli)
chr11_+_66824276 0.05 ENST00000308831.2
RHOD
ras homolog family member D
chr2_-_97534312 0.05 ENST00000442264.1
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr13_-_29069232 0.05 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1
fms-related tyrosine kinase 1
chr3_+_50192457 0.05 ENST00000414301.1
ENST00000450338.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr19_-_35992780 0.05 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr1_+_233749739 0.05 ENST00000366621.3
KCNK1
potassium channel, subfamily K, member 1
chr9_-_123639445 0.05 ENST00000312189.6
PHF19
PHD finger protein 19
chr3_+_50192499 0.05 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_-_33642151 0.05 ENST00000543586.1
TRIM62
tripartite motif containing 62
chrX_-_153979315 0.05 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GAB3
GRB2-associated binding protein 3
chr10_+_60094735 0.05 ENST00000373910.4
UBE2D1
ubiquitin-conjugating enzyme E2D 1
chr14_+_57735725 0.05 ENST00000431972.2
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr7_-_100493744 0.05 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr6_-_3912207 0.04 ENST00000566733.1
RP1-140K8.5
RP1-140K8.5
chr17_-_3796334 0.04 ENST00000381771.2
ENST00000348335.2
ENST00000158166.5
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr3_+_148847371 0.04 ENST00000296051.2
ENST00000460120.1
HPS3
Hermansky-Pudlak syndrome 3
chr11_-_73309112 0.04 ENST00000450446.2
FAM168A
family with sequence similarity 168, member A
chr19_+_42773371 0.04 ENST00000571942.2
CIC
capicua transcriptional repressor
chr7_+_2671663 0.04 ENST00000407643.1
TTYH3
tweety family member 3
chr19_+_13135731 0.04 ENST00000587260.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr16_+_838614 0.04 ENST00000262315.9
ENST00000455171.2
CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr12_-_59314246 0.04 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr9_-_93195771 0.04 ENST00000425666.1
ENST00000436671.1
RP11-389K14.3
RP11-389K14.3
chr6_+_31949801 0.04 ENST00000428956.2
ENST00000498271.1
C4A
complement component 4A (Rodgers blood group)
chr1_+_24120143 0.04 ENST00000374501.1
LYPLA2
lysophospholipase II
chr1_+_93544821 0.04 ENST00000370303.4
MTF2
metal response element binding transcription factor 2
chr11_-_2193025 0.04 ENST00000333684.5
ENST00000381178.1
ENST00000381175.1
ENST00000352909.3
TH
tyrosine hydroxylase
chr12_+_27091426 0.04 ENST00000546072.1
ENST00000327214.5
FGFR1OP2
FGFR1 oncogene partner 2
chr4_+_95917383 0.04 ENST00000512312.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_-_204436344 0.04 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr21_+_45148735 0.04 ENST00000327574.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr12_+_57390745 0.04 ENST00000600202.1
HBCBP
HBcAg-binding protein; Uncharacterized protein
chr4_-_40632140 0.04 ENST00000514782.1
RBM47
RNA binding motif protein 47
chr11_+_67071050 0.04 ENST00000376757.5
SSH3
slingshot protein phosphatase 3
chr12_+_27091316 0.04 ENST00000229395.3
FGFR1OP2
FGFR1 oncogene partner 2
chr15_+_77713222 0.03 ENST00000558176.1
HMG20A
high mobility group 20A
chr4_-_40632844 0.03 ENST00000505414.1
RBM47
RNA binding motif protein 47
chr10_+_21823243 0.03 ENST00000307729.7
ENST00000377091.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr19_-_14586125 0.03 ENST00000292513.3
PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr15_+_80351910 0.03 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr4_+_26578293 0.03 ENST00000512840.1
TBC1D19
TBC1 domain family, member 19
chr19_+_42772659 0.03 ENST00000572681.2
CIC
capicua transcriptional repressor
chr14_-_24017647 0.03 ENST00000555334.1
ZFHX2
zinc finger homeobox 2
chr2_-_75745823 0.03 ENST00000452003.1
EVA1A
eva-1 homolog A (C. elegans)
chr11_+_7598239 0.03 ENST00000525597.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr11_-_46142505 0.03 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr10_-_64028466 0.03 ENST00000395265.1
ENST00000373789.3
ENST00000395260.3
RTKN2
rhotekin 2
chr17_-_3794021 0.03 ENST00000381769.2
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr7_-_3214287 0.03 ENST00000404626.3
AC091801.1
LOC392621; Uncharacterized protein
chr17_-_39183452 0.03 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chrX_+_24711997 0.03 ENST00000379068.3
ENST00000379059.3
POLA1
polymerase (DNA directed), alpha 1, catalytic subunit
chr11_+_75526212 0.03 ENST00000356136.3
UVRAG
UV radiation resistance associated
chr15_+_73976715 0.03 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276
CD276 molecule
chr19_-_6433765 0.03 ENST00000321510.6
SLC25A41
solute carrier family 25, member 41
chr10_+_21823079 0.03 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr11_+_66824303 0.03 ENST00000533360.1
RHOD
ras homolog family member D
chr1_+_2487631 0.03 ENST00000409119.1
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr2_+_46770531 0.03 ENST00000482449.2
RHOQ
ras homolog family member Q
chr17_-_7080883 0.02 ENST00000570576.1
ASGR1
asialoglycoprotein receptor 1
chr2_-_29297127 0.02 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr19_+_34287751 0.02 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr1_-_1711508 0.02 ENST00000378625.1
NADK
NAD kinase
chr16_+_28858004 0.02 ENST00000322610.8
SH2B1
SH2B adaptor protein 1
chr5_+_112312399 0.02 ENST00000515408.1
ENST00000513585.1
DCP2
decapping mRNA 2
chr19_-_50169064 0.02 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
IRF3
interferon regulatory factor 3
chr17_-_39211463 0.02 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chrX_+_13707235 0.02 ENST00000464506.1
RAB9A
RAB9A, member RAS oncogene family
chr10_-_101945771 0.02 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr6_+_28109703 0.02 ENST00000457389.2
ENST00000330236.6
ZKSCAN8
zinc finger with KRAB and SCAN domains 8
chr4_-_186733363 0.02 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr11_-_46142615 0.02 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chrX_+_52926322 0.02 ENST00000430150.2
ENST00000452021.2
ENST00000412319.1
FAM156B
family with sequence similarity 156, member B
chr5_+_112312454 0.02 ENST00000543319.1
DCP2
decapping mRNA 2
chr14_-_65409502 0.02 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr15_+_63340553 0.02 ENST00000334895.5
TPM1
tropomyosin 1 (alpha)
chr17_+_18280976 0.02 ENST00000399134.4
EVPLL
envoplakin-like
chr17_-_53809473 0.02 ENST00000575734.1
TMEM100
transmembrane protein 100
chr17_-_39222131 0.02 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr1_+_93544791 0.02 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
MTF2
metal response element binding transcription factor 2
chr4_-_40632881 0.02 ENST00000511598.1
RBM47
RNA binding motif protein 47
chr17_+_28804380 0.02 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
GOSR1
golgi SNAP receptor complex member 1
chr1_+_16370271 0.02 ENST00000375679.4
CLCNKB
chloride channel, voltage-sensitive Kb
chr22_-_23922448 0.02 ENST00000438703.1
ENST00000330377.2
IGLL1
immunoglobulin lambda-like polypeptide 1
chr12_-_15038779 0.02 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr18_-_52989525 0.02 ENST00000457482.3
TCF4
transcription factor 4
chr17_-_39203519 0.01 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr2_-_27938593 0.01 ENST00000379677.2
AC074091.13
Uncharacterized protein
chr9_-_139357413 0.01 ENST00000277537.6
SEC16A
SEC16 homolog A (S. cerevisiae)
chr4_-_47839966 0.01 ENST00000273857.4
ENST00000505909.1
ENST00000502252.1
CORIN
corin, serine peptidase
chr19_+_35940486 0.01 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr17_-_62208169 0.01 ENST00000606895.1
ERN1
endoplasmic reticulum to nucleus signaling 1
chr17_-_5372229 0.01 ENST00000433302.3
DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chrX_+_153770421 0.01 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr14_-_65409438 0.01 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr6_+_90272339 0.01 ENST00000522779.1
ANKRD6
ankyrin repeat domain 6
chr17_-_5372068 0.01 ENST00000572490.1
DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr17_-_40428359 0.01 ENST00000293328.3
STAT5B
signal transducer and activator of transcription 5B
chr19_-_46142362 0.01 ENST00000586770.1
ENST00000591721.1
EML2
echinoderm microtubule associated protein like 2
chr12_-_27091183 0.01 ENST00000544548.1
ENST00000261191.7
ENST00000537336.1
ASUN
asunder spermatogenesis regulator
chr19_+_37095719 0.01 ENST00000423582.1
ZNF382
zinc finger protein 382
chr20_+_61924532 0.01 ENST00000358894.6
ENST00000326996.6
ENST00000435874.1
COL20A1
collagen, type XX, alpha 1
chr22_+_21369316 0.01 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chr8_+_110656344 0.01 ENST00000499579.1
RP11-422N16.3
Uncharacterized protein
chr4_+_111397216 0.01 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr21_-_39870339 0.01 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr13_+_102104980 0.01 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr11_+_120207787 0.01 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr7_-_107968921 0.01 ENST00000442580.1
NRCAM
neuronal cell adhesion molecule
chr16_-_2379688 0.01 ENST00000567910.1
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr9_+_35792151 0.01 ENST00000342694.2
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr12_+_27091387 0.01 ENST00000544111.1
FGFR1OP2
FGFR1 oncogene partner 2
chr4_-_66536196 0.01 ENST00000511294.1
EPHA5
EPH receptor A5
chr1_-_231004220 0.01 ENST00000366663.5
C1orf198
chromosome 1 open reading frame 198
chr7_+_107384579 0.01 ENST00000222597.2
ENST00000415884.2
CBLL1
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chrX_+_53078273 0.01 ENST00000332582.4
GPR173
G protein-coupled receptor 173
chr4_-_4228616 0.01 ENST00000296358.4
OTOP1
otopetrin 1
chr19_+_46806856 0.00 ENST00000300862.3
HIF3A
hypoxia inducible factor 3, alpha subunit
chr3_-_45837959 0.00 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr11_-_62689046 0.00 ENST00000306960.3
ENST00000543973.1
CHRM1
cholinergic receptor, muscarinic 1
chr11_+_64002292 0.00 ENST00000426086.2
VEGFB
vascular endothelial growth factor B
chr18_+_11752783 0.00 ENST00000585642.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr1_+_89990431 0.00 ENST00000330947.2
ENST00000358200.4
LRRC8B
leucine rich repeat containing 8 family, member B

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.3 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) sensory neuron axon guidance(GO:0097374) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.2 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.2 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 0.1 GO:2000646 lipid transport involved in lipid storage(GO:0010877) regulation of Cdc42 protein signal transduction(GO:0032489) positive regulation of receptor catabolic process(GO:2000646)
0.0 0.2 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.0 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.0 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.0 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0044301 climbing fiber(GO:0044301)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.0 GO:0031084 BLOC-2 complex(GO:0031084)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.0 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.0 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol