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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for ZKSCAN3
Z-value: 0.40
Motif logo
Transcription factors associated with ZKSCAN3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ZKSCAN3
|
ENSG00000189298.9 | zinc finger with KRAB and SCAN domains 3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZKSCAN3 | hg19_v2_chr6_+_28317685_28317761 | 0.73 | 1.0e-01 | Click! |
Activity profile of ZKSCAN3 motif
Sorted Z-values of ZKSCAN3 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_39786962 | 1.14 |
ENST00000333625.2
|
IFNL1
|
interferon, lambda 1 |
| chr14_-_106069247 | 0.33 |
ENST00000479229.1
|
RP11-731F5.1
|
RP11-731F5.1 |
| chr2_+_191745560 | 0.23 |
ENST00000338435.4
|
GLS
|
glutaminase |
| chr2_-_61244550 | 0.23 |
ENST00000421319.1
|
PUS10
|
pseudouridylate synthase 10 |
| chr12_-_3982548 | 0.22 |
ENST00000397096.2
ENST00000447133.3 ENST00000450737.2 |
PARP11
|
poly (ADP-ribose) polymerase family, member 11 |
| chr19_+_39759154 | 0.18 |
ENST00000331982.5
|
IFNL2
|
interferon, lambda 2 |
| chr5_-_95297534 | 0.17 |
ENST00000513343.1
ENST00000431061.2 |
ELL2
|
elongation factor, RNA polymerase II, 2 |
| chr17_-_62499334 | 0.15 |
ENST00000579996.1
|
DDX5
|
DEAD (Asp-Glu-Ala-Asp) box helicase 5 |
| chr1_+_93913665 | 0.14 |
ENST00000271234.7
ENST00000370256.4 ENST00000260506.8 |
FNBP1L
|
formin binding protein 1-like |
| chr1_+_226250379 | 0.14 |
ENST00000366815.3
ENST00000366814.3 |
H3F3A
|
H3 histone, family 3A |
| chr11_-_111320706 | 0.14 |
ENST00000531398.1
|
POU2AF1
|
POU class 2 associating factor 1 |
| chr12_-_3982511 | 0.14 |
ENST00000427057.2
ENST00000228820.4 |
PARP11
|
poly (ADP-ribose) polymerase family, member 11 |
| chr6_+_116850174 | 0.13 |
ENST00000416171.2
ENST00000368597.2 ENST00000452373.1 ENST00000405399.1 |
FAM26D
|
family with sequence similarity 26, member D |
| chr12_+_109535373 | 0.13 |
ENST00000242576.2
|
UNG
|
uracil-DNA glycosylase |
| chr16_-_832926 | 0.12 |
ENST00000293892.3
|
MSLNL
|
mesothelin-like |
| chr4_-_169239921 | 0.11 |
ENST00000514995.1
ENST00000393743.3 |
DDX60
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| chr19_+_52873166 | 0.10 |
ENST00000424032.2
ENST00000600321.1 ENST00000344085.5 ENST00000597976.1 ENST00000422689.2 |
ZNF880
|
zinc finger protein 880 |
| chr2_+_191221240 | 0.10 |
ENST00000409027.1
ENST00000458193.1 |
INPP1
|
inositol polyphosphate-1-phosphatase |
| chr18_-_74728998 | 0.10 |
ENST00000359645.3
ENST00000397875.3 ENST00000397869.3 ENST00000578193.1 ENST00000578873.1 ENST00000397866.4 ENST00000528160.1 ENST00000527041.1 ENST00000526111.1 ENST00000397865.5 ENST00000382582.3 |
MBP
|
myelin basic protein |
| chr5_+_65018017 | 0.09 |
ENST00000380985.5
ENST00000502464.1 |
NLN
|
neurolysin (metallopeptidase M3 family) |
| chr15_+_41624892 | 0.09 |
ENST00000260359.6
ENST00000450318.1 ENST00000450592.2 ENST00000559596.1 ENST00000414849.2 ENST00000560747.1 ENST00000560177.1 |
NUSAP1
|
nucleolar and spindle associated protein 1 |
| chr1_-_115259337 | 0.08 |
ENST00000369535.4
|
NRAS
|
neuroblastoma RAS viral (v-ras) oncogene homolog |
| chr12_+_109535923 | 0.08 |
ENST00000336865.2
|
UNG
|
uracil-DNA glycosylase |
| chr3_-_10052849 | 0.08 |
ENST00000437616.1
ENST00000429065.2 |
AC022007.5
|
AC022007.5 |
| chr6_-_35656712 | 0.07 |
ENST00000357266.4
ENST00000542713.1 |
FKBP5
|
FK506 binding protein 5 |
| chr2_-_175351744 | 0.07 |
ENST00000295500.4
ENST00000392552.2 ENST00000392551.2 |
GPR155
|
G protein-coupled receptor 155 |
| chr17_-_60142609 | 0.07 |
ENST00000397786.2
|
MED13
|
mediator complex subunit 13 |
| chr2_+_191745535 | 0.07 |
ENST00000320717.3
|
GLS
|
glutaminase |
| chrX_+_153775869 | 0.07 |
ENST00000424839.1
|
IKBKG
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma |
| chr1_+_93913713 | 0.06 |
ENST00000604705.1
ENST00000370253.2 |
FNBP1L
|
formin binding protein 1-like |
| chr3_-_122512619 | 0.06 |
ENST00000383659.1
ENST00000306103.2 |
HSPBAP1
|
HSPB (heat shock 27kDa) associated protein 1 |
| chr5_-_65017921 | 0.05 |
ENST00000381007.4
|
SGTB
|
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta |
| chrX_-_135338503 | 0.05 |
ENST00000370663.5
|
MAP7D3
|
MAP7 domain containing 3 |
| chr10_+_21823079 | 0.04 |
ENST00000377100.3
ENST00000377072.3 ENST00000446906.2 |
MLLT10
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| chr11_-_61062762 | 0.04 |
ENST00000335613.5
|
VWCE
|
von Willebrand factor C and EGF domains |
| chr8_+_123793633 | 0.04 |
ENST00000314393.4
|
ZHX2
|
zinc fingers and homeoboxes 2 |
| chr9_+_127023704 | 0.04 |
ENST00000373596.1
ENST00000425237.1 |
NEK6
|
NIMA-related kinase 6 |
| chr10_+_21823243 | 0.03 |
ENST00000307729.7
ENST00000377091.2 |
MLLT10
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| chr19_-_49258606 | 0.03 |
ENST00000310160.3
|
FUT1
|
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| chr1_-_19811132 | 0.02 |
ENST00000433834.1
|
CAPZB
|
capping protein (actin filament) muscle Z-line, beta |
| chr5_+_140079919 | 0.02 |
ENST00000274712.3
|
ZMAT2
|
zinc finger, matrin-type 2 |
| chr3_+_50316458 | 0.02 |
ENST00000316436.3
|
LSMEM2
|
leucine-rich single-pass membrane protein 2 |
| chr5_-_114598548 | 0.02 |
ENST00000379615.3
ENST00000419445.1 |
PGGT1B
|
protein geranylgeranyltransferase type I, beta subunit |
| chr14_-_80697396 | 0.02 |
ENST00000557010.1
|
DIO2
|
deiodinase, iodothyronine, type II |
| chr16_-_1429010 | 0.02 |
ENST00000513783.1
|
UNKL
|
unkempt family zinc finger-like |
| chr1_-_28415075 | 0.02 |
ENST00000373863.3
ENST00000436342.2 ENST00000540618.1 ENST00000545175.1 |
EYA3
|
eyes absent homolog 3 (Drosophila) |
| chr2_-_167232484 | 0.02 |
ENST00000375387.4
ENST00000303354.6 ENST00000409672.1 |
SCN9A
|
sodium channel, voltage-gated, type IX, alpha subunit |
| chr19_+_32836499 | 0.02 |
ENST00000311921.4
ENST00000544431.1 ENST00000355898.5 |
ZNF507
|
zinc finger protein 507 |
| chr2_-_61244308 | 0.02 |
ENST00000407787.1
ENST00000398658.2 |
PUS10
|
pseudouridylate synthase 10 |
| chr1_-_28415204 | 0.02 |
ENST00000373871.3
|
EYA3
|
eyes absent homolog 3 (Drosophila) |
| chr1_+_156123318 | 0.01 |
ENST00000368285.3
|
SEMA4A
|
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| chr7_+_155089486 | 0.01 |
ENST00000340368.4
ENST00000344756.4 ENST00000425172.1 ENST00000342407.5 |
INSIG1
|
insulin induced gene 1 |
| chr16_-_832054 | 0.00 |
ENST00000543963.1
|
MSLNL
|
mesothelin-like |
| chr19_-_42348692 | 0.00 |
ENST00000330743.3
ENST00000601246.1 |
LYPD4
|
LY6/PLAUR domain containing 4 |
| chrX_-_153775426 | 0.00 |
ENST00000393562.2
|
G6PD
|
glucose-6-phosphate dehydrogenase |
| chr7_-_155089251 | 0.00 |
ENST00000609974.1
|
AC144652.1
|
AC144652.1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZKSCAN3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) |
| 0.0 | 0.3 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.0 | 0.1 | GO:0060623 | pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623) |
| 0.0 | 0.1 | GO:1902809 | regulation of skeletal muscle fiber differentiation(GO:1902809) |
| 0.0 | 0.2 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.0 | 0.1 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.0 | 0.1 | GO:1904209 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 0.0 | 0.2 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.0 | 0.2 | GO:0045008 | depyrimidination(GO:0045008) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.1 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
| 0.0 | 0.1 | GO:0001740 | Barr body(GO:0001740) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.0 | 0.2 | GO:0097506 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 0.0 | 0.1 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) |
| 0.0 | 0.1 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.0 | 0.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |