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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF282

Z-value: 0.31

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Transcription factors associated with ZNF282

Gene Symbol Gene ID Gene Info
ENSG00000170265.7 zinc finger protein 282

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF282hg19_v2_chr7_+_148892557_1488925800.853.1e-02Click!

Activity profile of ZNF282 motif

Sorted Z-values of ZNF282 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_186262166 0.20 ENST00000307944.5
crystallin, gamma S
chr22_-_50970566 0.18 ENST00000405135.1
ENST00000401779.1
outer dense fiber of sperm tails 3B
chr6_+_151358048 0.15 ENST00000450635.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr22_-_50970506 0.15 ENST00000428989.2
ENST00000403326.1
outer dense fiber of sperm tails 3B
chr19_+_7953417 0.12 ENST00000600345.1
ENST00000598224.1
leucine rich repeat containing 8 family, member E
chr8_+_74888417 0.12 ENST00000517439.1
ENST00000312184.5
transmembrane protein 70
chr12_-_46766577 0.12 ENST00000256689.5
solute carrier family 38, member 2
chr18_-_54318353 0.12 ENST00000590954.1
ENST00000540155.1
thioredoxin-like 1
chr5_-_7869108 0.11 ENST00000264669.5
ENST00000507572.1
ENST00000504695.1
FAST kinase domains 3
chr14_+_55590646 0.11 ENST00000553493.1
lectin, galactoside-binding, soluble, 3
chr6_+_10748019 0.10 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
synaptonemal complex protein 2-like
transmembrane protein 14B
chr18_+_54318893 0.10 ENST00000593058.1
WD repeat domain 7
chr3_-_170587974 0.10 ENST00000463836.1
ribosomal protein L22-like 1
chr1_+_17248418 0.09 ENST00000375541.5
ciliary rootlet coiled-coil, rootletin
chr16_-_70239683 0.09 ENST00000601706.1
Uncharacterized protein
chr19_-_49121054 0.08 ENST00000546623.1
ENST00000084795.5
ribosomal protein L18
chr6_-_136571400 0.08 ENST00000418509.2
ENST00000420702.1
ENST00000451457.2
mitochondrial fission regulator 2
chr6_+_144471643 0.08 ENST00000367568.4
syntaxin 11
chr4_+_39460659 0.08 ENST00000513731.1
lipoic acid synthetase
chr6_+_10747986 0.08 ENST00000379542.5
transmembrane protein 14B
chr4_+_52709229 0.07 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
DCN1, defective in cullin neddylation 1, domain containing 4
chr19_-_39390212 0.07 ENST00000437828.1
sirtuin 2
chr6_+_139349817 0.06 ENST00000367660.3
ABRA C-terminal like
chr17_-_73937116 0.06 ENST00000586717.1
ENST00000389570.4
ENST00000319129.5
Fas (TNFRSF6) binding factor 1
chr12_-_13248598 0.06 ENST00000337630.6
ENST00000545699.1
germ cell associated 1
chr14_+_71788096 0.06 ENST00000557151.1
signal-induced proliferation-associated 1 like 1
chr22_-_50970919 0.06 ENST00000329363.4
ENST00000437588.1
outer dense fiber of sperm tails 3B
chr16_+_29467780 0.06 ENST00000395400.3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr11_+_66278080 0.06 ENST00000318312.7
ENST00000526815.1
ENST00000537537.1
ENST00000525809.1
ENST00000455748.2
ENST00000393994.2
Bardet-Biedl syndrome 1
chr2_-_197664366 0.06 ENST00000409364.3
ENST00000263956.3
general transcription factor IIIC, polypeptide 3, 102kDa
chr20_-_62284766 0.05 ENST00000370053.1
stathmin-like 3
chr17_+_42422629 0.05 ENST00000589536.1
ENST00000587109.1
ENST00000587518.1
granulin
chr19_+_39390320 0.05 ENST00000576510.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr9_+_139221880 0.05 ENST00000392945.3
ENST00000440944.1
G-protein signaling modulator 1
chr16_+_30207122 0.05 ENST00000395137.2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr2_-_188378368 0.05 ENST00000392365.1
ENST00000435414.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr6_+_139117251 0.05 ENST00000401414.3
epithelial cell transforming sequence 2 oncogene-like
chr7_+_16828866 0.05 ENST00000597084.1
Uncharacterized protein
chrX_-_49121165 0.05 ENST00000376207.4
ENST00000376199.2
forkhead box P3
chr21_+_35747773 0.05 ENST00000399292.3
ENST00000399299.1
ENST00000399295.2
small integral membrane protein 11
chr1_-_2126192 0.04 ENST00000378546.4
chromosome 1 open reading frame 86
chr12_-_125473600 0.04 ENST00000308736.2
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr19_-_6110457 0.04 ENST00000586302.1
regulatory factor X, 2 (influences HLA class II expression)
chrX_+_47004639 0.04 ENST00000345781.6
RNA binding motif protein 10
chr3_+_10312604 0.04 ENST00000426850.1
TatD DNase domain containing 2
chr17_+_8191815 0.04 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chrX_-_13835461 0.04 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr20_+_62492566 0.04 ENST00000369916.3
abhydrolase domain containing 16B
chr18_+_54318566 0.04 ENST00000589935.1
ENST00000357574.3
WD repeat domain 7
chr1_-_108735440 0.04 ENST00000370041.4
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr22_+_45898712 0.04 ENST00000455233.1
ENST00000348697.2
ENST00000402984.3
ENST00000262722.7
ENST00000327858.6
ENST00000442170.2
ENST00000340923.5
ENST00000439835.1
fibulin 1
chr5_+_65892174 0.04 ENST00000404260.3
ENST00000403625.2
ENST00000406374.1
microtubule associated serine/threonine kinase family member 4
chr10_+_11865347 0.04 ENST00000277570.5
proline and serine-rich protein 2
chr12_+_93964158 0.04 ENST00000549206.1
suppressor of cytokine signaling 2
chr2_-_68479614 0.04 ENST00000234310.3
protein phosphatase 3, regulatory subunit B, alpha
chr5_+_78365577 0.03 ENST00000518666.1
ENST00000521567.1
betaine--homocysteine S-methyltransferase 2
chr10_-_114206649 0.03 ENST00000369404.3
ENST00000369405.3
zinc finger, DHHC-type containing 6
chr13_-_95248511 0.03 ENST00000261296.5
TDP-glucose 4,6-dehydratase
chr1_-_54303934 0.03 ENST00000537333.1
NDC1 transmembrane nucleoporin
chr19_+_44617511 0.03 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
zinc finger protein 225
chr16_+_67204400 0.03 ENST00000563439.1
ENST00000432069.2
ENST00000564992.1
ENST00000564053.1
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr5_+_167718604 0.03 ENST00000265293.4
WW and C2 domain containing 1
chr17_+_44039704 0.03 ENST00000420682.2
ENST00000415613.2
ENST00000571987.1
ENST00000574436.1
ENST00000431008.3
microtubule-associated protein tau
chr11_+_82904858 0.03 ENST00000260047.6
ankyrin repeat domain 42
chr1_+_40723779 0.03 ENST00000372759.3
zinc metallopeptidase STE24
chr6_+_129204337 0.03 ENST00000421865.2
laminin, alpha 2
chr12_+_122150646 0.03 ENST00000449592.2
transmembrane protein 120B
chr17_+_42422637 0.03 ENST00000053867.3
ENST00000588143.1
granulin
chr19_+_7953384 0.03 ENST00000306708.6
leucine rich repeat containing 8 family, member E
chr19_+_39390587 0.03 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chrX_-_47004878 0.03 ENST00000377811.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr1_+_13910479 0.03 ENST00000509009.1
podoplanin
chr1_+_151171012 0.03 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr17_+_7942424 0.03 ENST00000573359.1
arachidonate 15-lipoxygenase, type B
chr17_+_42422662 0.03 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
granulin
chr6_-_17706618 0.03 ENST00000262077.2
ENST00000537253.1
nucleoporin 153kDa
chr1_+_226250379 0.03 ENST00000366815.3
ENST00000366814.3
H3 histone, family 3A
chr6_-_137314371 0.03 ENST00000432330.1
ENST00000418699.1
RP11-55K22.5
chr11_+_63998006 0.03 ENST00000355040.4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr2_+_242289502 0.03 ENST00000451310.1
septin 2
chr3_-_170588163 0.03 ENST00000295830.8
ribosomal protein L22-like 1
chr17_-_77924627 0.03 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1 domain family, member 16
chr15_-_83736091 0.03 ENST00000261721.4
BTB (POZ) domain containing 1
chr19_-_58220517 0.02 ENST00000512439.2
ENST00000426889.1
zinc finger protein 154
chr4_+_39460620 0.02 ENST00000340169.2
ENST00000261434.3
lipoic acid synthetase
chr7_+_139025875 0.02 ENST00000297534.6
chromosome 7 open reading frame 55
chr20_-_33872518 0.02 ENST00000374436.3
eukaryotic translation initiation factor 6
chr14_+_58711539 0.02 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
proteasome (prosome, macropain) subunit, alpha type, 3
chr20_-_43150601 0.02 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
serine incorporator 3
chr16_+_29802036 0.02 ENST00000561482.1
ENST00000160827.4
ENST00000569636.2
ENST00000400750.2
kinesin family member 22
chr1_+_13910757 0.02 ENST00000376061.4
ENST00000513143.1
podoplanin
chr19_-_46285736 0.02 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
dystrophia myotonica-protein kinase
chr1_+_35247859 0.02 ENST00000373362.3
gap junction protein, beta 3, 31kDa
chr1_+_47799446 0.02 ENST00000371873.5
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chrX_-_135849484 0.02 ENST00000370620.1
ENST00000535227.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr15_-_44955842 0.02 ENST00000427534.2
ENST00000559193.1
ENST00000261866.7
ENST00000535302.2
ENST00000558319.1
spastic paraplegia 11 (autosomal recessive)
chr1_-_2126174 0.02 ENST00000400919.3
ENST00000420515.1
ENST00000378543.2
ENST00000400918.3
chromosome 1 open reading frame 86
chr10_+_51572408 0.02 ENST00000374082.1
nuclear receptor coactivator 4
chr2_+_232260254 0.02 ENST00000287590.5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr4_-_153457197 0.02 ENST00000281708.4
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_-_9129735 0.02 ENST00000377424.4
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr5_+_156887027 0.01 ENST00000435489.2
ENST00000311946.7
NIPA-like domain containing 4
chr1_-_54303949 0.01 ENST00000234725.8
NDC1 transmembrane nucleoporin
chr17_+_7942335 0.01 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
arachidonate 15-lipoxygenase, type B
chr1_+_2004901 0.01 ENST00000400921.2
protein kinase C, zeta
chr10_+_51572339 0.01 ENST00000344348.6
nuclear receptor coactivator 4
chr16_+_50727479 0.01 ENST00000531674.1
nucleotide-binding oligomerization domain containing 2
chr4_+_39460689 0.01 ENST00000381846.1
lipoic acid synthetase
chr2_+_219283815 0.01 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
villin 1
chr15_+_51200859 0.01 ENST00000261842.5
adaptor-related protein complex 4, epsilon 1 subunit
chr5_+_150816595 0.01 ENST00000520111.1
ENST00000520701.1
ENST00000429484.2
solute carrier family 36 (proton/amino acid symporter), member 1
chr7_-_158497431 0.01 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
non-SMC condensin II complex, subunit G2
chr5_+_140552218 0.01 ENST00000231137.3
protocadherin beta 7
chr17_+_41323204 0.01 ENST00000542611.1
ENST00000590996.1
ENST00000389312.4
ENST00000589872.1
neighbor of BRCA1 gene 1
chr11_-_321340 0.01 ENST00000526811.1
interferon induced transmembrane protein 3
chr1_+_2005425 0.01 ENST00000461106.2
protein kinase C, zeta
chr15_+_51200871 0.01 ENST00000560508.1
adaptor-related protein complex 4, epsilon 1 subunit
chr8_-_21988558 0.01 ENST00000312841.8
hair growth associated
chrX_-_13835147 0.01 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr13_+_50656307 0.01 ENST00000378180.4
deleted in lymphocytic leukemia 1 (non-protein coding)
chr11_+_100784231 0.00 ENST00000531183.1
Rho GTPase activating protein 42
chr5_+_86415919 0.00 ENST00000515750.1
RP11-72L22.1
chr17_+_55183261 0.00 ENST00000576295.1
A kinase (PRKA) anchor protein 1
chr8_-_23261589 0.00 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
lysyl oxidase-like 2
chr11_+_111957497 0.00 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
succinate dehydrogenase complex, subunit D, integral membrane protein
chr6_-_36807762 0.00 ENST00000244751.2
copine V
chr12_-_49582978 0.00 ENST00000301071.7
tubulin, alpha 1a
chr4_+_88343952 0.00 ENST00000440591.2
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr12_-_49582837 0.00 ENST00000547939.1
ENST00000546918.1
ENST00000552924.1
tubulin, alpha 1a
chr17_-_73389854 0.00 ENST00000578961.1
ENST00000392564.1
ENST00000582582.1
growth factor receptor-bound protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF282

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0002652 regulation of tolerance induction dependent upon immune response(GO:0002652)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.0 0.1 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.0 0.0 GO:0071789 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.0 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.0 0.0 GO:0030327 prenylated protein catabolic process(GO:0030327) CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0070762 nuclear pore transmembrane ring(GO:0070762)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.0 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.0 0.0 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)